EP1711630A2 - Methods of assessing a tissue inflammatory response using expression profiles of endothelial cells - Google Patents

Abstract

The invention provides methods of assessing a tissue inflammatory response, comprising making a quantitative determination of the level of at least five transcripts shown in Table 1, or proteins encoded thereby, in a sample; and comparing the abundance of said transcripts or proteins so determined with the level of said transcript obtained from a control sample. Methods for diagnosis of a condition with which a tissue inflammatory response is associated are also provided, as are gene chip arrays and protein based assays suitable for use in these methods. Assay methods for determining a modulator of a tissue inflammatory response or a condition associated therewith also form part of the invention.

Description

METHODS- OF ASSESSING A TISSUE INFLAMMATORY RESPONSE USING EXPRESSION PROFILES OF ENDOTHELIAL CELLS

Field of the Invention

The present invention relates to gene expression profiles of endothelial cells and to the use of these profiles in the assessment of disease conditions and in therapy.

Background to the Invention

The migration of leucocytes into tissues is a key part of the normal function of the immune system, mucosal surfaces, the uterine endometrium, mammary gland and ovary. However, emigration of leucocytes from the intravascular space into the tissues can also be stimulated by the inflammation response. Inflammation is a response of the body to damage or infection, and typically involves movement of leucocytes and proteins across endothelial walls and into tissues.

The inflammation response involves a number of signalling molecules. Some of these act on the endothelium to cause the endothelial cells to adhere less tightly to one another and/or to make their surfaces adhesive to passing white blood cells. Other signals act as chemoattractants for the leucocytes, or promote expression of adhesion molecules on the leucocytes. Yet other signals regulate leucocyte activation and survival.

Signalling molecules include quick release' mediators that are involved in increased vascular permeability, such as histamine. These act synergistically with the later stage ^process induced' mediators. These later stage mediators include chemokines, which attract leukocytes into areas of inflammation, and cytokines, subsequently released from inflammatory cells and activated endothelial cells. TNF-α, IL-lβ and IL-8 are inflammatory mediators found at high concentrations at sites of inflammation, and endothelial cells possess receptors for these mediators (1-3) .

TNF-α is a prototypical cytokine, which was originally isolated from macrophages, but is now known to be generated by a variety of cells, including lymphocytes, monocytes, neutrophils, T-cells, myocytes and smooth muscle cells. TNF receptor 1 engagement by TNF-α leads to the initiation of apoptosis in a wide variety of cell types. Receptor binding also results in sustained NF-κB activation, required for expression of a repertoire of genes involved not only in the inflammatory response, but also increased cell survival and enhanced resistance to TNF-α-induced apoptosis. Signalling pathways also activated in endothelial cells by TNF-α include the phosphatidylinositol (PI) kinase dependent kinases, stress activated protein kinases (SAPK) and mitogen activated protein kinases (MAPK) (3, 4) .

IL-lβ is another prototypical cytokine. The main source of secreted Il-lβ is monocytes, but it is also generated by a wide variety of other cell types, including, notably, activated macrophages, neutrophils, platelets, T- and B-cells, natural killer (NK) cells, endothelial cells, SMCs (smooth muscle cells) and fibroblasts. IL-lβ is synthesised as a precursor and, once proteolytically cleaved, can activate many cell types with roles in immunity and inflammation. As with TNF-α, IL-lβ activates the NF-κB (nuclear factor KB) survival pathway, as well as MAPK cascades p42/p44, p38 and Jnk (5) .

IL-8 is a chemokine that has been closely linked with angiogenesis . The main sources of IL-8 are monocytes, neutrophils, T-cells, NK cells, endothelial cells, fibroblasts and epithelial cells. IL-8 is involved in the process of leukocyte transmigration into tissues, as well as other aspects of the inflammatory response. Its production is not constitutive but is induced by pro-inflammatory cytokines. IL-8 binds to heparin and induces endothelial cell migration, proliferation and survival in vitro (β) . IL-8 and its receptors appear to be critical in angiogenesis and tumour progression (7, 8).

Molecular mediators of inflammation such as TNF-α, IL-1 and IL-8 act on target cells within inflamed tissues such as endothelial cells, fibroblasts and leukocytes. The effects of combinations of inflammatory mediators such as these three is synergistic - i.e. the action of these factors ^λin concert' is likely to be different from the sum of their individual effects .

The inflammatory response of tissues, such as is typified in inflammatory diseases, typically involves the abnormal or excessive movement of leucocytes and proteins into the tissue. This can result in a large number of acute or chronic inflammation disorders. Leucocyte and protein movement can also play a role in conditions which are not primarily inflammatory diseases, but in which the tissues demonstrate an inflammatory response. For example, the diseases of atherosclerosis and endometriosis may rely on the migration of leucocytes into the lesions. Repair of tissue necrosis that occurs in stroke or heart attack also requires inflammation responses. Tumour growth may be regulated by leucocytes that migrate from the blood into the tumour. These leucocytes release factors that directly promote tumour cell growth and tumour angiogenesis. In addition, leucocytes that migrate into tumours mediate an immune responses towards tumour cell- specific antigens with subsequent anti-tumour effect. The role of inflammation in tumour growth is therefore complex, and involves a balance between stimulatory and inhibitory pathways .

In view of the role of inflammation responses in a wide variety of pathological conditions, there is a continuing need for the development of methods for the assessment or treatment of human medical conditions associated with such responses. In addition, inflammation responses are essential features of physiological processes such as female fertility and wound healing. There is a need for methods to modulate inflammatory responses in order to modulate these processes.

Disclosure of the Invention

We have analysed the changes in transcript abundance which occur when human umbilical vein endothelial cells (HUVECs) are contacted with a mixture of TNF-α, Interleukin-lβ and Interleukin-8. These factors are typically present at increased concentrations in tissues during an inflammatory response and are secreted by a wide variety of cell types over sustained periods.

Primary cell cultures of endothelial cells derived from a number of different individuals were tested in order to obtain a consensus set of transcripts regulated in endothelial cells of multiple individuals during an inflammatory response. Data were analysed using a novel combination of bio-informatic algorithms, including a modified Loess normalisation and a CyberT algorithm.

In addition, we analysed expression in different endothelial cells types obtained from different parts of the body, namely HUVEC, human coronary artery endothelial cells (HCAEC) and human uterine microvascular endothelial cells (UtMVEC) . It was found that many transcripts, including those which were most strongly regulated in HUVECs, were consistently regulated by inflammatory signals in all three cell types.

Thus, in the present invention we have used a novel methodology to identify for the first time a pattern of changes in the regulation of expression of certain genes in endothelial cells responding to inflammatory signals as well as a consensus set of genes whose transcripts are modified in response to inflammatory signals in endothelial cells derived from many individuals, and which are therefore likely to have wide applicability to populations of patients.

Accordingly, the present invention provides a means for assessment of (e.g., diagnosis, prognosis or monitoring of) a tissue inflammatory response or a condition associated therewith. Such a response is typically associated with one of a number of conditions and it may also involve the migration of leucocytes across an endothelium. Therefore, by determining a tissue inflammatory response, a determination may also be made of the condition with which that response may be associated. Also, the finding that a number of transcripts are regulated in these responses and hence conditions, both of genes known as such and from ESTs, allows the provision of novel assay targets and the development of new therapies for such conditions.

Accordingly, in a first aspect, the present invention provides a method of assessing a tissue inflammatory response, comprising: making a quantitative determination of the level of at least five transcripts shown in Table 1, or proteins encoded thereby, in a sample; and comparing the abundance of said transcripts or proteins so determined with the level of said transcripts or proteins obtained from a control sample of cells.

Preferably, the sample comprises cells obtained from a site within a patient believed to be affected by a tissue inflammatory response, suitably endothelial cells, or patient blood, serum or urine.

In another aspect, the invention provides a gene chip array suitable for use in the above-described method of the invention, comprising at least five nucleic acids suitable for detection of at least five transcripts shown in Table 1; optionally a control specific for said transcripts; and optionally at least one control for the gene chip.

In a further aspect, the invention provides a protein based assay suitable for use in the above-described method of the invention, for the assessment of at least five proteins encoded by transcripts including those shown in Table 1; optionally a control specific for said proteins; and optionally at least one control for the assay.

In a further aspect, the invention provides an assay method for determining a modulator of a tissue inflammatory response or a condition associated therewith, wherein said method comprises a) providing a protein encoded by transcripts from Table 1; b) bringing the protein into contact with a candidate modulator of its activity; c) determining whether said candidate modulator is capable of modulating the activity of the protein;

or wherein said method comprises; a) providing an endothelial cell in culture; b) bringing said cell into contact with a candidate modulator of said tissue inflammatory response; and c) determining whether said candidate modulator is capable of modulating the level of at least one transcript selected from the transcripts of Table 1.

Modulators obtained by such methods may be used in a method of modulating tissue inflammatory responses in a human or animal subject, e.g., so as to treat a condition discussed below.

In another aspect, the identification of genes of previously unknown function and of ESTs, has allowed new potential targets for therapeutic intervention to be developed. Thus, the invention provides a vector comprising a sequence encoding a transcript from Table lb operably linked to a promoter for the transcription of said sequence. Such vectors are useful in the expression of proteins which may be therapeutics or therapeutic targets. The vectors may also have direct therapeutic use in themselves, e.g., in gene therapy applications .

Description of the Tables

Table la lists transcripts of genes whose levels are regulated in endothelial cells by inflammatory mediators TNFα, IL-lβ, and IL-8, where the genes have a previously ascribed function.

Table lb lists transcripts of genes or ESTs whose levels are regulated in endothelial cells by inflammatory mediators TNFα, IL-lβ and IL-8, where the genes/ESTs do not have a previously ascribed function. Table 2a provides nucleic acid sequences for each of the probes mentioned in Table la.

Table 2b provides nucleic acid sequences for each of the probes mentioned in Table lb.

Detailed Description of the Invention

Reference herein to Table 1 and 2 is to be construed as meaning Tables la or lb together, or Tables 2a and 2b together, respectively, unless the context is explicit to only one of these component parts of Table 1 or Table 2 respectively.

Conditions associated with tissue inflammatory responses In its first aspect, the present invention is concerned with a method for the assessment of a tissue inflammatory response. It is generally recognised, as is discussed above, that ^• leucocytes are involved in the inflammatory responses of tissues. An inflammatory response may involve the movement of leucocytes across an endothelium. However, proteins which are involved in such an inflammatory response may also cause the movement of leucocytes to the inflamed tissue, may participate in or be responsible for the activation of the leucocytes, the activation and angiogenesis of endothelial cells, or may influence the inflammatory response by inhibiting the apoptosis of leucocytes or endothelial cells.

A tissue inflammatory response is typically involved with a condition or disease state of the patient. By "condition" as used herein is meant any disease state or body response which involves, causes or is associated with the tissue inflammatory response. The tissue inflammatory response may either be excessive or unwanted, for example as may be the case in an inflammatory disease such as those discussed herein below, or may be insufficient, such as, for example in conditions associated with defective adhesion proteins, such as leucocyte adhesion deficiency types 1 and 2 (LAD-1 and LAD-2) .

Tissue inflammatory responses and trans-endothelial leucocyte movement can be affected by changes in the endothelial cells, for example by changes in adhesion molecule expression, which alters the ability of the leucocytes to adhere to the endothelial cells, or alters the chemokine-mediated recruitment of leucocytes to the inflammed tissue. In respect of the present invention, it is preferred that the changes in the endothelial cells are in response to an inflammatory signal .

A condition to be assessed by the method of the invention may be one in which endothelial cells in the location of the inflammatory response or affected by the inflammatory response are altered so as to promote an inflammatory process and allow the movement of leucocytes across that endothelium.

Typically the movement of leucocytes across an endothelium occurs as a response to inflammatory signals. Therefore, a tissue inflammatory response to be assessed by the method of the invention is one in which inflammatory signals are issued. Exemplary of such conditions are inflammatory diseases, vasculitic syndromes, atherosclerosis and associated diseases, conditions involving tumour growth and chronic transplant rejection.

Inflammatory diseases include inflammatory bowel disorders, psoriasis, ischemic reperfusion, adult respiratory distress syndrome, asthma, allergic rhinitis, dermatitis, meningitis, encephalitis, uveitis, diseases involving leucocyte diapedesis, central nervous system inflammatory disorders, Alzheimer's, endometriosis, multiple sclerosis, multiple organ injury syndrome, alcoholic hepatitis, bacterial pneumonia, antigen-antibody complex mediated diseases; inflammation of the lung (including pleurisy, alveolitis, pneumonia, chronic bronchitis, bronchiectasis, cystic fibrosis and COPD) , vasculitis, polyarteritis nodosa, giant cell arteritis, microscopic polyarteritis, pre-eclampsia and autoimmune diseases (such as rheumatoid arthritis, Sjorgen's syndrome, and the multiple forms of renal failure which are primarily due to autoimmune attack directed at the endothelial cells in the kidney glomeruli) .

In atherosclerosis and associated diseases, such as coronary heart disease, peripheral vascular disease and cerebrovascular accident, leucocyte migration across the endothelial layer into blood vessel walls at the site of an atherosclerotic plaque is driven by inflammatory signals from leucocytes associated with the plaque and the underlying endothelial cells. Plaque instability and subsequent rupture leading to thrombosis and vessel stenosis or occlusion may be associated with inflammatory effects on the endothelial cells within the area of the plaque.

Tumour growth may be regulated by leucocytes that migrate from the blood into the tumour, and which release factors that directly promote tumour cell growth and tumour angiogenesis. Thus, cancers and especially those involving solid tumours may also be a relevant therapeutic indication.

Chronic transplant rejection critically involves immune cell migration across blood vessels and immune attack directed towards endothelial cells and hence is suitable for assessment by the method of the invention.

These and other conditions associated with the release of inflammatory signals may be the subject of methods of the present invention.

Assessment of a tissue inflammatory response In the present invention, it will be understood that the determination of cells "obtained from a site" believed to be affected by a tissue inflammatory response is reference to an in vi tro method practiced on a sample after removal from the body. The step of removing the sample, e.g., by biopsy, is not part of the invention as such.

In addition to or as an alternative to techniques such as tissue biopsies, bodily fluids such as blood, serum and urine may be collected to reveal inflammation-induced changes within these fluids. Such changes may be demonstrated by, for example, an alteration in the sample in the abundance of endothelial cell-derived proteins that are encoded by the sequences in table 1.

Accordingly, the present invention provides a method for the diagnosis of a condition with which a tissue inflammatory response is associated comprising the determination of the abundance of endothelial cell-derived proteins encoded by at least five of the transcripts of Table 1 in a sample from a patient suspected of suffering from such a condition.

As explained above, the data obtained in the present invention shows that contacting endothelial cells with TNFα, IL-lβ and IL-8 results in characteristic changes to certain transcripts, taking into account variation between individuals and between different endothelial tissues. These changes may take the form either of a pattern of response or may affect individual transcripts. Accordingly, it is possible to use these characteristic changes as a reference for the diagnosis of conditions such as those discussed above.

In addition to, or as an alternative to, diagnosis, assessment of the condition may be a determination of the severity or precise clinical sub-type of the condition. It may also be a method of prognosis of the future course of the condition. Furthermore assessment can be over a period of time, for example in the monitoring of the treatment of a condition.

In its first aspect, the present invention provides a method of assessing a tissue inflammatory response by comparing the transcript levels in a sample taken from a patient showing an inflammatory response with the transcript levels of the same genes in a control sample.

As discussed above, the sample may be either of cells from a specific tissue demonstrating an inflammatory response, such as endothelial cells, or may alternatively be of a protein- containing bodily fluid, such as blood, serum or urine.

A control sample for the above methods is typically a sample of unaffected cells, that is cells from a tissue not demonstrating a tissue inflammatory response or cells believed not to be affected by the condition. It is preferred that the test and control sample are both of the same cell type and more preferred that the test and control sample are of endothelial cells. Most preferably, the test and control sample are of the same endothelial cell type, i.e. from the same tissue location. If required, the control sample may be taken from a population of subjects. Where a population of subjects is used, the comparison may be made with the average (e.g., mean or median) transcript level in samples of cells from said population. Affected tissue may also be used as a control. Typically the affected tissue will be from a patient other than that from which the test sample was taken. It is generally preferred that, if affected tissue is being used as a control, the patient from which that sample is removed has or is believed to have the same condition as the patient from which the test sample is removed.

In some embodiments, the method of the invention may comprise the use of more than one control; for example the sample to be tested may be compared to a normal or unaffected sample from the same patient and the transcript level of an affected sample from another patient or patients.

As discussed above, the method of the invention allows for the monitoring of a condition, either before, during or after treatment. Where the test sample is from a patient having or believed to have tissue inflammation, it is generally preferred that a sample is also obtained from the patient at an earlier time point, so as to provide a historical record.

In another embodiment, the method allows for assessment of the effectiveness of a particular treatment. By comparing the severity of the tissue inflammation in a single patient at two or more time points, it is possible to determine whether or not a particular treatment regime is having a positive effect. The effectiveness of any one regime may differ from patient to patient, or during the course of the disease. In a preferred embodiment, the invention is performed by looking at the level of a plurality of gene transcripts or plurality of proteins derived from these transcripts. This is because we have found that between individual subjects, the transcript level of individual genes may vary. It is therefore desirable that the transcript level is assessed for several genes. For example, it may be assessed for at least

5, preferably at least 10 and more preferably at least 20 transcripts or proteins derived from transcripts of Table 1.

The level of expression may be determined either for the genes or proteins individually or in specific combinations, or a pattern of expression of a plurality of genes may be determined.

In the first aspect of the present invention, the level of the transcripts assessed is compared in a test and a control sample. It may be that the response to an inflammatory signal causes the level of the transcripts either to rise or to fall. Hence there may be either up-regulation of the transcripts in response to an inflammatory signal or down-regulation. It is not important to the present invention whether there is either up-regulation or down-regulation, but rather that there is change from the control.

As an aid to determining the difference in transcript or protein regulation between a test and a control sample, the specific amount of up- or down-regulation may be determined. This can be expressed as a "fold" increase or decrease. It is not important to the present invention how large is the increase or decrease in transcript level, but rather it is important that there is a significant change from the control. In the present invention it is generally preferred that there be at least a two-fold change, i.e. increase or decrease, in the transcript level. There is no upper limit on the amount of increase or decrease in transcript or protein level, but we have found that a 50-fold change in the level of certain transcripts and apparent e novo upregulation of certain proteins can be demonstrated.

Furthermore, in the assessment of up- or down-regulation of transcript or protein levels, it is not necessary for all transcripts or proteins being assessed to be regulated by the same amount. Of more significance in this respect is the establishment of a pattern of regulation.

In one embodiment of the present invention, the transcripts or proteins assessed may include one or from transcripts from one or more families or groups of protein. Preferably, the method involves determining the levels of at least one transcript or protein in two or more of such families or groups of protein, preferably three, four, five or more, and more preferably each of such families or groups of protein.

Typical such groups or families include proteases, bone morphogenetic proteins, cell signalling proteins, proteins involved in transcriptional regulation, enzymes, cell cycle regulation proteins, cell communication proteins, nuclear proteins, complement proteins, extracellular matrix proteins, proteosomes, heavy metal binding proteins, TNF-receptor superfamily proteins, HLA proteins, cell adhesion proteins, cytokines/chemokines, cytokine/chemokine receptors, cytoskeletal proteins, regulators of apoptosis, growth factors and growth factor receptors.

It is generally preferred that the transcripts or proteins assessed include one or more selected from cytokines/- chemokines, cytokine/chemokine receptors, cytoskeletal proteins, extracellular matrix protins, regulators of apoptosis, growth factors and growth factor receptors.

Of particular interest to the method of the present invention is the regulation of particular transcripts or proteins. These can be assessed either per se or as part of a pattern of regulation. Therefore, in the method of the present invention, it is preferred that the transcripts or proteins assessed include one or more of: colony stimulating factor 3 (granulocyte) , colony stimulating factor 2 (granulocyte- macrophage) , granulocyte chemotactic protein 2, diubiquitin, ELAM-1, TNF-induced protein 6, Exodus 1, IL-lβ, VCAM-1, ICAM- 1, IAP1, TNF-inducible A20, RIPK2, MMP 10, TRAF1, JAK binding protein, dual specificity phosphatase 4, IL-6, IL-8, Gro- gamma, MCP-1, Gro-beta, Gro-alpha, ENA-78, fractalkine, small inducible cytokine subfamily A14, small inducible cytokine A5, LI7 receptor, toll/interleukin 1 receptor-like 4, CCAAT, MAD- 3, COX-2, Mn SOD, NO synthase, L-kynurenine hydrolase, tissue factor pathway inhibitor 2, laminin gamma 2, Toll-like receptor 2, natural killer cell transcript 4, TNF-alpha induced protein 2, cationic amino acid transporter 2A, fatty acid binding protein 4, TNF receptor superfamily member lib and TNF superfamily member 9.

It is more preferred that in the method of the present invention the transcripts or proteins assessed include one or more of: colony stimulating factor 3 (granulocyte) , colony stimulating factor 2 (granulocyte-macrophage) , granulocyte chemotactic protein 2, diubiquitin, ELAM-1, TNF-induced protein 6, Exodus 1 and IL-lβ.

Alternatively, the method involves determining a pattern of expression of transcripts, wherein the transcripts include at least some of the transcripts illustrated in Table 1 herein. The transcript or protein level of a gene or genes may be determined by any suitable means. Where many different gene transcripts are being examined, a convenient method is by hybridisation of the sample (either directly or after generation of cDNA or cRNA) to a gene chip array.

Where gene chip technology is used, the genes (this term used herein includes the ESTs of Table 1) are all present in commercially available chips from Affymetrix, and these chips may be used in accordance with protocols from the manufacturer. Generally, methods for the provision of microarrays and their use may also be found in, for example, WO84/01031, WO88/1058, WO89/01157, W093/8472, W095/18376/ W095/18377, W095/24649 and EP-A-0373203 and reference may also be made to this and other literature in the art.

Where many different proteins are being examined, a convenient method is antibody chip, multi-target ELISA, or proteomic analysis. Generally, methods for the provision of protein assays and their use may also be found in, for example, U.S. Patent 6,329,209 and U.S. Patent No. 2,656,508. Such methods are common within the art. Further information on such methods may be obtained by reference to http: //www.marketresearch. com/map/prod/904611.html

Table 1 provides the names of genes and these may be used to obtain their DNA sequences and encoded protein sequences from databases such as Genbank. In addition, the particular sequences used on the Affymetrix chip we have used may be determined by the Affymetrix reference numbers supplied in the Table, which are publicly available and may be related directly to Genbank reference numbers. EST gene sequences in some cases are also given by Genbank reference numbers. Those of skill in the art may refer to either of the Affymetrix reference number or the Genbank reference number in practicing the present invention.

Table 2 provides cDNA sequence information for each of the probes used on the Affymetrix chip that are also listed in Table 1. Table 1 lists the probe set used to obtain the specific protein/EST listed therein and Table 2 provides the cDNA sequence for each probe set mentioned in Table 1.

In Tables 2a and 2b, "n" represents in each case a region of the nucleic acid that was not probed by the probe set sequences on the gene chips. Thus, in order to make the arrays as specific as possible, only selected regions of the full cDNA' s have been used, with the exclusion of some intervening sequences. Excluded sequences are those in which the single nucleotide code (a, g, c or t) has been replaced with "n".

Alternatively, or in addition, quantitative PCR methods may be used, e.g. based upon the ABI TaqMan™ technology, which is widely used in the art. It is described in a number of prior art publications, for example reference may be made to WO00/05409. PCR methods require a primer pair which target opposite strands of the target gene at a suitable distance apart (typically 50 to 300 bases) . Suitable target sequences for the primers may be determined by reference to Genbank sequences as mentioned above.

Gene Chips

Although the prior art provides a gene chip which includes, as part of a very large array, the genes of one or more of Tables la and lb, the identification of a relatively small set of genes of use in assessing the conditions discussed above allows the provision of a small chip specifically designed to be suitable for use in the present invention (a tailored gene array) .

Thus the invention provides a gene chip array comprising at least five nucleic acids suitable for detection of at least five transcripts shown in Table 1 (either directly or after generation of cDNA or cRNA) ; optionally a control specific for said transcripts; and optionally at least one control for said gene chip.

In an alternative embodiment of this aspect, the invention provides a gene chip array for detection of at least five transcripts shown in Table 1 comprising at least five nucleic acids selected from Table 2 capable of detecting the presence of said at least five transcripts; optionally a control specific for said transcripts and optionally at least one control for said gene chip.

The gene chip array comprises at least five different nucleic acids, preferably at least 10 or 20 different nucleic acids.

Desirably, the number of sequences in the array will be such that where the number of nucleic acids suitable for detection of the Table 1 transcripts (or the number of Table 2 sequences) is n, the number of control nucleic acids specific for individual transcripts is n' , where n' is from 0 to 2n, and the number of control nucleic acids (e.g. negative controls or controls for detection of "housekeeping" transcripts, abundant endothelial cell transcripts, transcripts which have a higher level of expression in endothelial cells, transcripts which have a higher level of expression in the particular endothelial type being assessed, or the like) on said gene chip is m where m is from 0 to 100, preferably from 1 to 30, then n + n' + m represent at least 50%, preferably 75% and more preferably at least 90% of the nucleic acids on said chip.

Protein Chips

As discussed above in relation to gene chips, the provision of the transcripts and proteins encoded thereby in Table 1 allows for the production of appropriate tailored protein chips. Such chips may be used in the form of an antibody chip, or may encompass multi-target ELISA, or proteomic analysis. Generally, methods for the provision of protein assays and their use may be found in, for example, U.S. Patent 6,329,209 and U.S. Patent No. 2,656,508. Such methods are common within the art.

Accordingly, in a further aspect, the present invention provides a protein based-assay suitable for use in the above- described method of the invention, for the assessment of at least five proteins encoded by transcripts including those shown in Table 1; optionally a control specific for said proteins; and optionally at least one control for the assay.

In a preferred embodiment, the protein-based assay is an antibody chip or ELISA, preferably multi-target ELISA.

Assay Methods

Assay methods of the present invention may be practiced in a wide variety of formats, for example on protein or nucleic acid components or in whole cells in culture.

The present invention provides in its second aspect an assay method for a modulator of a tissue inflammatory response or a condition associated therewith, comprising: (a) providing a protein encoded by a transcript of Table l; (b) bringing said protein into contact with a candidate modulator of its activity; and (c) determining whether said candidate modulator is capable of modulating the activity of said protein.

Where the response of an endothelial cell to inflammatory signals involves down-regulation of a transcript, the assay is preferably for an activator of the protein, and the assay preferably involves determining whether the modulator is capable of increasing the activity of the protein. In this embodiment, the assay may be carried out under conditions where the protein normally shows low or no activity.

Where the response of an endothelial cell to inflammatory signals involves up-regulation of a transcript, the assay is preferably for an inhibitor of the activity of the protein, and the assay preferably involves determining whether the modulator is capable of reducing the activity of the protein. In this embodiment, the assay may be carried out under conditions in which the protein is normally active.

In this assay method, the determination of modulation of activity will depend upon the nature of the protein being assayed. For example, proteins with enzymatic function may be assayed in the presence of a substrate for the enzyme, such that the presence of a modulator capable of modulating the activity results in a faster or slower turnover of substrate. The substrate may be the natural substrate for the enzyme or a synthetic analogue. In either case, the substrate may be labelled with a detectable label to monitor its conversion into a final product. For proteins with a ligand binding function, such as receptors, the candidate modulator may be examined for ligand binding function in a manner that leads to antagonism or agonism of the ligand binding property.

For proteins with DNA binding activity, such as transcription regulators, the DNA binding or transcriptional activating activity may be determined, wherein a modulator is able to either enhance or reduce such activity. For example, DNA binding may be determined in a mobility shift assay. Alternatively, the DNA region to which the protein binds may be operably linked to a reporter gene (and additionally, if needed, a promoter region and/or transcription initiation region between said DNA region and reporter gene) , such that transcription of the gene is determined and the modulation of this transcription, when it occurs, can be seen. Suitable reporter genes include, for example, ^' chloramphenicol acetyl transferase or more preferably, fluorescent reporter genes such as green fluorescent protein.

Alternatively, or in a third aspect, the present invention provides an assay method for a modulator of a tissue inflammatory response or a condition associated therewith comprising: (a) providing an endothelial cell in culture; (b) bringing said cell into contact with a candidate modulator of said condition; and (c) determining whether said candidate modulator is capable of modulating the level of at least one transcript selected from the transcripts of Table 1.

In the first step of this method, an endothelial cell is cultured. Any appropriate method may be used for the harvesting and culture of the cells. Techniques for the culture of endothelial cells are common in the art.

Candidate modulator compounds may be natural or synthetic chemical compounds used in drug screening programmes. Extracts of plants, microbes or other organisms, which contain several characterised or uncharacterised components, may also be used. Combinatorial library technology (including solid phase synthesis and parallel synthesis methodologies) provides an efficient way of testing a potentially vast number of different substances for the ability to modulate an interaction. Such libraries and their use are known in the art for all manner of natural products, small molecules and peptides, among others. Many such libraries are commercially available and sold for drug screening programmes of the type now envisaged by the present invention.

A further class of candidate modulator comprises antibodies or binding fragments thereof which bind a protein target.

Examples of antibody fragments, capable of binding an antigen or other binding partner, are the Fab fragment consisting of the VL, VH, Cl and CHI domains; the Fd fragment consisting of the VH and CHI domains; the Fv fragment consisting of the VL and VH domains of a single arm of an antibody; the dAb fragment which consists of a VH domain; isolated CDR regions and F(ab')2 fragments, a bivalent fragment including two Fab fragments linked by a disulphide bridge at the hinge region. Single chain Fv fragments are also included. An antibody specific for a protein may be obtained from a recombinantly produced library of expressed immunoglobulin variable domains, e.g. using lambda bacteriophage or filamentous bacteriophage which display functional immunoglobulin binding domains on their surfaces; for instance see WO92/01047. Such a technique allows the rapid production of antibodies against an antigen, and these antibodies may then be screening in accordance with the invention.

Another class of candidate molecules is peptides, based upon a fragment of the protein sequence to be inhibited. In particular, fragments of the protein corresponding to portions of the protein which interact with other proteins or with DNA, may be a target for small peptides which act as competitive inhibitors of protein function. Such peptides may be for example from 5 to 20 amino acids in length.

The peptides may also provide the basis for design of mimetics. Such mimetics will be based upon analysis of the peptide to determine the amino acid residues or portions of their side chains essential and important for biological activity to define a pharmacophore followed by modelling of the pharmacophore to design mimetics which retain the essential residues or portions thereof in an appropriate three-dimensional relationship. Various computer-aided techniques exist in the art in order to facilitate the design of such mimetics.

Cell based assay methods can be configured to determine expression of the gene either at the level of transcription or at the level of translation. Where transcripts are to be measured, then this may be determined using the methods of the first aspect of the invention described above, e.g. on gene chips, by multiplex PCR, or the like.

As above, where the transcript is one which is down-regulated in response to inflammatory signals, the assay is preferably for agents which increase the expression of the gene (e.g., by increasing the quantity of the transcript) . Such an agent may comprise the coding sequence of the gene itself (i.e., it may be a gene therapy vector) . Where the transcript is one which is up-regulated in response to inflammatory signals, the assay is preferably for agents which decrease the expression of the gene.

Cell based assay methods may be used to screen candidate modulators as described above. They may also be used to screen further classes of candidate modulator, including antisense oligonucleotides . Such oligonucleotides are typically from 12 to 25, e.g. about 15 to 20 nucleotides in length, and may include or consist of modified backbone structures, e.g. methylphosphonate and phosphorothioate backbones, to help stabilise the oligonucleotide. The antisense oligonucleotides may be derived from the coding region of a target gene or be from the 5' or 3' untranslated region. Candidate molecules may further include RNAi, i.e. short double stranded RNA molecules which are sequence specific for a gene transcript, or a longer RNA sequence which can be processed by the cell into siRNA, and which can be provided to the cell e.g., as a DNA sequence (eliRNA, or expressed long interfering RNA) . They may also include ribozymes which specifically target the transcript mRNA, i.e., a catalytic RNA molecule which cleaves other RNA molecules of a particular nucleic acid sequence. General methods for the construction of ribozymes are known in the art.

In a preferred embodiment of these aspects of the invention, the assay methods described above are used to determine modulators of activity of a protein or level of a transcript from Table lb.

Modulators obtained in accordance with these aspects of the present invention may be used in methods of modulating tissue inflammatory responses and/or conditions associated therewith, e.g., inflammatory conditions, in a patient.

The present invention therefore also provides a pharmaceutical composition comprising a modulator of a tissue inflammatory response and/or a condition associated therewith together with a pharmaceutically acceptable carrier therefor.

Generally, the modulator will be formulated with one or more pharmaceutically acceptable carriers suitable for a chosen route of administration to a subject. For solid compositions, conventional non-toxic solid carriers include, for example, pharmaceutical grades of mannitol, lactose, cellulose, cellulose derivatives, starch, magnesium stearate, sodium saccharin, talcum, glucose, sucrose, magnesium carbonate, and the like may be used. Liquid pharmaceutically administrable compositions can, for example, be prepared by dissolving, dispersing, etc, a modulator and optional pharmaceutical adjuvants in a carrier, such as, for example, water, saline aqueous dextrose, glycerol, ethanol, and the like, to thereby form a solution or suspension. If desired, the pharmaceutical composition to be administered may also contain minor amounts of non-toxic auxiliary substances such as wetting or emulsifying agents, pH buffering agents and the like, for example, sodium acetate, sorbitan monolaurate, triethanolamine sodium acetate, sorbitan monolaurate, triethanolamine oleate, etc. Actual methods of preparing such dosage forms are known, or will be apparent, to those skilled in this art; for example, see Remington's Pharmaceutical Sciences, Mack Publishing Company, Easton, Pennsylvania, 15th Edition, 1975. The composition or formulation to be administered will, in any event, contain a quantity of the active compound (s) in an amount effective to alleviate the symptoms of the subject being treated. Routes of administration may depend upon the precise condition being treated, though since endothelial cells form the lining of the vasculature, administration into the blood stream (e.g. by i.v. injection) is one possible route.

In addition, the present invention provides a modulator of a tissue inflammatory response and/or a condition associated therewith for use in therapy.

Furthermore, the present invention provides the use of a modulator of a tissue inflammatory response in the manufacture of a medicament for the treatment of a condition associated with said response.

Vectors

The identification of a number of ESTs and other genes of previously unknown function associated with regulation of endothelial cells by inflammatory signals provides the basis for novel vector systems useful in aspects of the invention described above, as well as further aspects described herein below.

Preferably, the sequence encoding a transcript listed in Table lb is operably linked to a control sequence which is capable of providing for expression of the coding sequence by a host cell, i.e., the vector is an expression vector.

The term "operably linked" refers to a juxtaposition wherein the components described are in a relationship permitting them to function in their intended manner. A control sequence "operably linked" to a coding sequence is ligated in such a way that expression of the coding sequence is achieved under condition compatible with the control sequences. Suitable host cells include bacteria, eukaryotic cells such as mammalian and yeast, and baculovirus systems. Mammalian cell lines available in the art for expression of a heterologous polypeptide include Chinese hamster ovary cells, HeLa cells, baby hamster kidney cells, COS cells and many others.

The vectors may include other sequences such as promoters or enhancers to drive the expression of the inserted nucleic acid, nucleic acid sequences so that the polypeptide is produced as a fusion and/or nucleic acid encoding secretion signals so that the polypeptide produced in the host cell is secreted from the cell.

The vectors may contain one or more selectable marker genes, for example an ampicillin resistance gene in the case of a bacterial plasmid or a neomycin resistance gene for a mammalian vector.

Vectors may further include enhancer sequences, terminator fragments, polyadenylation sequences and other sequences as appropriate.

Vectors may be used in vitro, for example for the production of RNA or used to transfect or transform a host cell. The vector may also be adapted to be used in vivo, for example in methods of gene therapy. Systems for cloning and expression of a polypeptide in a variety of different host cells are well known. Vectors include gene therapy vectors, for example vectors based on adenovirus, adeno-associated virus, retrovirus (such as HIV or MLV) or alpha virus vectors.

Promoters and other expression regulation signals may be selected to be compatible with the host cell for which the expression vector is designed. For example, yeast promoters include S. cerevisiae GAL4 and ADH promoters, S. pombe nmtl and adh promoter. Mammalian promoters include the metallothionein promoter which is can be included in response to heavy metals such as cadmium. Viral promoters such as the SV40 large T antigen promoter or adenovirus promoters may also be used. All these promoters are readily available in the art.

Vectors for production of polypeptides encoded by a transcript of Table lb for use in gene therapy include vectors which carry a mini-gene sequence.

Vectors may be transformed into a suitable host cell as described above to provide for expression of a polypeptide of the invention. Thus, in a further aspect the invention provides a process for preparing polypeptides encoded by a transcript of Table lb which comprises cultivating a host cell transformed or transfected with an expression vector as described above under conditions to provide for expression by the vector of a coding sequence encoding the polypeptides, and recovering the expressed polypeptides. Polypeptides may also be expressed using in vitro systems, such as reticulocyte lysate .

Polypeptides or fragments thereof in substantially isolated form encoded by an EST or gene of Table lb form a further aspect of the present invention. Fragments of the polypeptides will preferably be at least 20 amino acids in size, and preferably from 25 amino acids up to the full length of the polypeptide.

A further aspect of the invention is nucleic acid sequences which encode said polypeptides and fragments thereof. Such nucleic acid sequences may be included in vectors such as those described above.

For further details see, for example, Molecular Cloning: a Laboratory Manual: 2nd edition, Sambrook et al . , 1989, Cold Spring Harbor Laboratory Press. Many known techniques and protocols for manipulation of nucleic acid, for example in preparation of nucleic acid constructs, mutagenesis, sequencing, introduction of DNA into cells and gene expression, and analysis of proteins, are described in detail in Current Protocols in Molecular Biology, Ausubel et al. eds., John Wiley & Sons, 1992.

Where a gene or EST of Table lb is present in a vector, it may be linked in-frame to a translational initiation region for translation of said sequence, or alternatively it may be in an anti-sense orientation for transcription of anti-sense RNA.

Examples

TNFa, IL-lβ and Interleukin-8 regulate transcript abundance To allow a study of the effect of TNFα, IL-lβ and Interleukin- 8 on transcript abundance, seven independent primary cultures of HUVEC were cultured with a mixture of 15ng/mL of each of TNF-α, Interleukin-lβ and Interleukin 8 for 24 hours. The RNAs extracted from these cultures were then used to prepare complex cRNA probes, which were hybridised to an Affymetrix U95A genechip (a 12, 600-element Affymetrix gene array chip).

Analysis of Gene Chip Data

Transcript abundance data ("average differences") were globally scaled to bring the median gene expression of each chip (excluding control genes) to 1. To ensure transcript expression levels were comparable between arrays, the "LOESS" function of the "R" statistical software system was applied to the log transformed average difference values of each array in comparison to a control array. The control array chosen was that which bore the closest similarity to the other six controls by Euclidean distance.

Normalised transcript abundance data was then compared using the CyberT algorithm (version 7.03; sliding window=301, Bayes estimate=21) . This algorithm is an unpaired T-test, modified by the inclusion of a Baysian prior based on the variance of the other transcripts in the data set (Long et al , 2001, J. Biol Chem 276, 19937-19944).

For further statistical analysis, the "R" statistical software system and GeneSpring Expression Analysis Software (Silicon Genetics, Redwood City, Ca) , were used.

Individual transcripts were categorised according to the functions of the proteins they encoded, using the GO database (www.geneontology.org) , Entrez (www.ncbi.nlm.nih.gov/entrez) or OMIM (www.ncbi.nlm.nih. gov: 80/entrez/Omim) databases.

In the Tables, fold changes are expressed as unpaired means over the seven experiments (i.e., mean of inflammatory treated/mean of control) .

Difference in transcript levels in different endothelial cell types

To determine whether the modulation of the transcriptome is comparable amongst different endothelial cell types, we obtained a further culture using one each of human coronary artery endothelial cells (HCAEC) and human uterine microvascular endothelial cells (UtMVEC) . The three different cell types were treated with inflammatory signals as above, and the extent to which the transcript abundance is regulated in each of the three cell types was assessed. A pattern of regulation between the three cell types was also determined. It was found that most transcripts are regulated in all three cell types, while some are regulated in only two or only one of these cell types.

Those transcripts which are regulated in all three cell types are believed to be particularly useful in the various methods of the present invention, since they are likely to be meaningful in a variety of inflammatory conditions affecting distinct organs.

Moreover, it was also found that the transcripts which are modulated by inflammatory signals in all three endothelial cell types tend also to be strongly modulated by inflammatory signals in HUVEC.

Consensus da ta

Table la and lb show a consensus set of transcripts. These were selected on the basis that their level before and after treatment with inflammatory mediators differs by a factor of two or more (in either direction) , with a Baysian P value of less than 0.001. These have been grouped according to gene family.

Table 1 shows the extent of regulation in HUVEC cells, and also in HCAEC and UtMVEC cells.

ESTs

A number of ESTs and genes of previously unknown function identified as relevant to the present invention are of particular interest in the various methods of the invention and as possible therapeutics for use in treatments. These are summarised in Table lb. The specific sequences of the probes used to isolate these ESTs are shown in Table 2b.

Materials and Methods : Prepara tion of endothelial cells

HUVECs isolated from seven different individuals were cultured in Microvascular Endothelial Cell Growth Medium-2 (EBM-MV, Biowhittaker) . Medium was supplemented with a proprietary mixture of human Epidermal Growth Factor, Hydrocortisone, Vascular Endothelial Growth Factor, human Fibroblast Growth Factor, human recombinant Insulin-like Growth Factor, Ascorbic Acid, Gentamicin, Amphotericin-B and FBS (5%) (Microvascular Bulletkit™ reagents, Biowhittaker. At passage 5, each HUVEC isolate was divided between two 175cm² culture flasks and grown to 70% confluence. For each HUVEC isolate, growth medium in one flask was replaced with fresh medium containing a cocktail of 15 ng each IL-8, IL-lβ and TNF-α. As a control, medium in replicate cultures was replaced with fresh medium only. Cytokine-treated HUVECs and controls were cultured for a further 24 hrs

Single donor-derived human coronary artery ECs and uterine myometrial microvascular ECs were purchased from Biowhittaker. Cells were cultured and treated under identical conditions as HUVECs

RNA Extraction

RNA was extracted from each culture using Trizol reagent (Gibco/BRL, UK) , followed by a clean up through an RNeasy™ spin column (Qiagen, UK) and ethanol precipitation. RNA^' integrity was assessed using an Aligent 2100 bioanalyser. Analysis of RNA

Biotinylated target cRNA was prepared according to Affymetrix protocol, hybridised to Affymetrix human U95Av2 chips and globally scaled using Microarray Suite Version 4.0 or 5.0 software.

References Schraufstaffer, I. U., Chung, J. , and Burger, M. (2001) IL-8 activates endothelial cell CXCRl and CXCR2 through Rho and Rac signaling pathways. American Journal of Physiology 280, L1094-L1103 Dinarello, C. A. (1998) Interlukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Intern Rev Immunol 16, 457-499 Aggarwal, B. B. (2000) Tumour necrosis factor receptors associated signalling molecules and their role in activation of apoptosis, JNK and NF-kB. Annals of Rheuma tic Disease 59 (suppl) , iβ-ilβ Madge, L. A., and Pober, J. S. (2001) TNF Signalling in Vascular Endothelial Cells. Experimental and Molecular Pathology 70, 317-325 O'Neill, L. A. J. , and Dinarello, C. A. (2000) The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense. Immunology Today 21, 206-209 Li, A., Dubey, S., Varney, M. L., and Singh, R. K. (2002) Interleukin-8-induced proliferation, survival, and MMP production in CXCRl AND CXCR2 expressing human umbilical vein endothelial cells. Microvascular Research 64, 476- 481 Strieter, R. M., Polverini, P. J. , Arenberg, D. A., Walz, A., Opdendakker, G., Van Damme, J. , and Kunkel, S. L. (1995) Role of C-X-C chemokines as regulators of angiogenesis in lung cancer. Journal of Leukocyte Biology 57, 752-762 Kitadai, Y., Haruma, K. , Su ii, K. , Yamamoto, S., Ue, T., Yokozaxi, H., Yasui, W., Ohmoto, Y., Kajiyama, G., Fidler, I. J. , and Tahara, E. (1998) Expression of interleukin-8 correlates with vascularity in human gastric carcinomas. American Journal of Pathology 152, 93-100

Table la. Transcripts regulated by inflammatory mediators

Table lb. Genes and ESTs of unknown function, regulated by inflammatory mediators

Table 2a: Probe sequences for identification of transcripts of Table la

>1736_at HG-U95Av2 agtaaaccccaagcaggcactgcccgcccacaggatgtgaaccgcagagaccaacagagg aatccaggcacctctaccacgccctcccagcccaattctgcgggtgtccaagacac gag atgggcccatgccgtagacatctggactcagtgctgcagcaactccagactgaggtctac cgaggggctcaaacactctacgtgcccaattgtgaccatcgaggcttctaccggaagcgg cagtgcc

>34021_at HG-U95Av2 caagaatcccaaactcaccaggatgctcacatttaagttttacatgcccaagaaggccac agaactgaaacatcttcagtgtctagannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnrinnnnagggatctgaaacaacattcatgtgtgaat gctgatgagac agcaaccattgtagaatttctgaacagatggattacnnnnnnnnnnnrinnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncttctatttatttaaa tatttaaattttatatttattgttgaatgtatggtttgctacctattgtaac

>35061_at HG-U95Av2 ggagtcaagccctt aagtcaaaagcatc atgtgtcgtaaagcattcctcaaacattt tttcatgcaaatacacanttctttccccaaatatcatgtagcacatcaatatgtagggaa acattct atgcatcatttggtttgtttta aaccaattcattaaatgtaat ca aaaa tgtactatgaaaaaaattatacgctatgggatactggcaacagtgcacatatttcataac caaattagcagcaccggtcttaatttgatgtttttcaacttttattcattgagatgtttt gaagcaattaggatatgtgtgtttactgtactttttgttttgatccgtttgtataaatga tagcaa a cttggacacatttga

>36444_s_at HG-U95Av2 ttccatgc actagtgc gac gc gcatctcctacaccccacgaagcatcccgtgttca ctcctggagagt actttgaaacgaacagcgagtgc ccaagccgggtg ca cttcctc accaagaaggggcgacgtttctgtgccaaccccag gataagcaagttcaggtttgcatg agaatgctgaagctggacacacggatcaagaccaggaagaattgaacttgtcaaggtgaa gggacacaagttgccagccaccaactttcttgcctcaactaccttcctgaattatttttt taagaagcatttattcttgtgttctggatttagagcaat catc

>36782_s_at HG-U95Av2 ttcttccaata gacacctggaagcagtccacccagcgcctgcgcaggggcctgcctgcc ctcctgcgtgcccgccggggtcacgtgc cgccaaggagctcgaggcgttcagggaggcc aaacgtcaccgtcccctgattgc ctacccacccaagaccccgcccacgggggcgccccc ccagagatggccagcaatcggaagtgagcaaaactgccgcaagtctgcagcccggcgcca ccatcctgcagcctcctcctgaccacggannnnnnnnnnnnnnnnnnnnncgaaaatctc tcggttccacgtccccctggggcttctcctgacccagtccccgtgccccgcctccccgaa acaggc ac ctcctcggccccctccatcgggctgaggaagcacagcagcatcttcaaac atgtacaaaatcgattggctttaaaca

>37319_at HG-U95Av2 cccaagaaggtctggcaaagtcaggctcagggagactctgccctgc gcagacctcggtg tggacacacgctgcatagagctctccttgaaaacagaggggtctcaagacattctgcc a cc

>431_at HG-U95Av2 actctaagtggcattcaaggagtacctctctctagaaccgtacgctgtacctgcatcagc a tagtaatcaacctgttaatccaaggtctttagaaaaacttgaaattattcctgcaagc caattttgtccacgtgttgagatcattgctacaatgaaaaagaagggtgagaagagatgt ctgaatccagaatcgaaggccatcaagaatttac gaaagcagttagcaaggaaa >1006_at HG-U95Av2 ctgaggaacccctggtgcccacaaaatctgttccttcgggatctgagatgccagccaagt gtgatcctgctttgtccttcgatgccatcagcactctgaggggagaatatctgttcttta aagacagatatttttggcgaagatcccactggaaccctgaacctgaatttcatttgattt ctgcattttggccctctcttccatcatatttggatgctgcatatgaagttaacagcaggg acaccgtttttatttttaaaggaaatgagttctgggccatcagaggaaatgaggtacaag caggttatccaagaggcatccataccctgggttttcctccaaccataaggaaaattgatg cagctgtttctgacaaggaaaagaagaaaacatact ctttgcagcggacaaatactgga gat ga gaaaatagccagtccatggagcaaggcttccctagactaatagc gatgact ttccaggagttgagcctaaggt gatgc gtat acaggcatttggatttttct c tct tcagtgga ca cacagtttgagtttgaccccaatgccaggatggtgacacaca a taa agagtaa

>1024_at HG-U95Av2 aagctctgaagaactctctggaagcccctgggcccagtacctagctggctctgtgagggt gctgactggcttcagcaagttagaactagccaaaccaggaccctgtcca

>1052_s_at HG-U95Av2 agaacgagaagctgcaccagcgcgtggagcagctcacgcgggacctggccggcctccggc agttcttcaagcagctgcccagcccgcccttcctgccggccgccgggacagcagactgcc ggtaacgcgcggccggggcgggagagactcagcaacgacccatacctcagacccgacggc ccggagcggacgccctgctgccgacgccagagccgccgcgtgcccgctgcagtttcttgg acatagaccaaagaagctacagcctggacttaccaccactaaactgcgagagaagctaaa cgtgtttattttcccttaaattatttttgtaatggtagctttttctacatct actcctg ttga gcagctaaggtacatttgtaaaaagaaaaaaaaccagacttttcagacaaaccct ttgtattgtagataagagg

>1058_at HG-U95Av2 ctaagcttttctctca agcgtagacctagggaagggatgggaagattgcccagtccccg atggctgcgcacacaggaggcggcggacgacaaggcaagtgagtttgcactgtcagcccc agaccgtaagcttggctacac gatgtttttctt actaagga actattcaaaaattaa cattttcatctcagtaagtttttagaacatcaaaatgttttctgagctccaagtggctag gttgtaaaagttt ataataatttgcaattaaaataca gatacata aatccattaaa gactagtgggaatgtatcagccagagtagcaagtaatttttgttt a aaatcatagtat ctgtca cttgcagtattaccaatgctgttgtaaattgaatttaaagtggta aaaaaa aactgttaaacaatttt a ctgtttgtatatcttactataga

>1061_at HG-U95Av2 tcatgccaagacag a cagacacagccccagaagggggcatta gggccctgcctcccc a aggccatttggactctgccttcaaacaaaggcagttcagtccacaggcatggaagctg tgaggggacaggcctgtgcgtgccatccagagtcatctcagccctgcctttctctggagc attctgaaaacagatattctggcccagggaatccagccatgacccccacccctctgccaa ag actcttaggtgccagtctggtaactgaactccctctggaggcaggcttgagg

>1069_at HG-U95Av2 ggttgaatgtttgtccttaggataggcctatgtgctagcccacaaagaatattgtctcat tagcctgaatgtgccataagactgaccttttaaaatgttttgagggatctgtggatgctt cgttaatttgttcagccacaatttattgagaaaatattctgtgtcaagcactgtgggttt taatatttttaaatcaaacgctgattacagataatagtatttatataaataattgaaaaa aattttcttttgggaagagggagaaaatgaaataaatatcattaaagataactcaggaga atcttctttacaa

>1086_at HG-U95Av2 agatgtgtccccaacatccccacagcccgagggcctccttgtcctgcagcaagtgggcga ctattgcttcctccccggcctggggcccggccctctctcgctccggagtaaaccttcttc cccgggacccggtcctgagatcaagaacctagaccaggcttttcaagtcaagaagccccc aggccaggctgtgccccaggtgcccgtcattcagctcttcaaagccctgaagcagcagga ctacctgtctctgcccccttgggaggtcaacaagcctggggaggtgtgttgagaccccca ggcctagacaggcaaggggatggagagggcttgccttccctcccgcctgaccttcctcag tcatttctgcaaagccaaggggcagcctcctgtcaaggtagctagaggcctgggaaagga gatagccttgctccggcccccttgaccttcagcaaatcacttctctccctgcgctcacac agacacacacacacacacgtacatgcacacatttttcctgtcaggttaa

>1102_s_at HG-U95Av2 gtgaaggttgctgaggctctgacccagtgagattacagaggaagt a cctctgcctccc attctgaccacccttctcattccaacagtgagtctgtcagcgcaggtttagtttac caa tctccccttgcactaaag a gtaaag atgtaaacaggagacaggaaggtggtgcttac a ccttaaaggcaccatctaatagcgggttactttcacatacagccctcccccagcagtt gaatgacaacagaagcttcagaagtttggcaatagtttgcatagaggtaccagcaatatg taaatagtgcagaatctcat ggttgccaataatacactaattcctttcta cctacaac aagagttta

>1105_s_at HG-U95Av2 ctagctccaaaaccatcccaggtcattct ca cctcacccaggattctcctgtacctgc tcccaatctgtgttcctaaaagtgattctcactctgcttc catctcctacttacatgaa tacttctctctt

>1113_at HG-U95Av2 aagatgaacacagctggtcacagataaggccattgctagtaacttttggcca gatggaa aagggcatcctctccacaaaagagaaaaacgtcaagccaaacacaaacagcggaaacgcc ttaagtccagctgtaagagacaccctttgtacgtggacttcagtgacgtggggtggaatg actggattgtggctcccccggggtatcacgccttttactgccacggagaatgcccttttc ctctggctgatcatctgaactccactaa ca gccattgttcagacgttggtcaactctg ttaactctaagattcctaaggca gc gtgtcccgacagaactcagtgc a ctcgatgc tgtaccttgacgagaatgaaaaggttgtattaaagaactatcaggacatggttgtggagg gttgtgggtgtcgctagtacagcaaaattaa

>1114_at HG-U95AV2 caggattagccgatcgttacctcaagggagtgggaattgggcccagctccggcccctcct ggtcacctttggccatgatggccggggccatgccttgacccgacgccggagggccaagcg tagccctaagcatcactcacagcgggccaggaagaagaataagaactgccggcgccactc gctc atgtggacttcagcgatgtgggctggaatgactggattgtggccccaccaggcta ccaggccttctactgccatggggactgcccctttccactggctgaccacctcaactcaac caaccatgccattgtgcagaccctggtcaattctgtcaattccagta ccccaaagcctg ttgtgtgcccactgaactgagtgccatctcca gctgtacctggatgagtatgataaggt ggtactgaaaaat atcaggagatggtagtagagggatgtgggtgccgctgagatcaggc agtccttgaggatagacagatatac

>1126_s_at HG-U95Av2 aaagctagtga caacagtggcaatggagctgtggaggacagaaagccaagtggactcaa cggagaggccagcaagtctcaggaaatggtgcatttggtgaacaaggagtcgtcagaaac tccagaccagttta gacagctgatgagacaaggaacctgcagaatgt

>1173_g_at HG-U95Av2 TIGRSequence

>1184_at HG-U95Av2 tcagctcttgcaagaggactccctcaatgtggctgacttgacttccctccgggccccact ggacatccccatcccagaccctccacccaagga ga gagatggaaacagataagcagga gaagaaagaagtccctaagtgtggatttctccctgggaatgagaaagtcctgtccctgct tgccctggttaagccagaagtctggactctcaaagagaaatgcattctgg gattacatg gatccaacacc ga ccccaagattgaagatggaaatgattttggggtagcaatccagga gaagg gctggagagggtgaatgccgtcaagaccaaagtggaagctttccagacaaccat ttccaagtacttctcagaacgtg.ggga gctgtggccaaggcctccaaggagactcatgt aatggattaccgggccttggtgcatgagcgagatgaggcagcctatggggagctcagggc catggtgctggacctgagggccttctatgctgagctttatcatatcatcagcagcaacct ggagaaa

>1207_at HG-U95Av2 ttctccgaggtctggactttcttcattcacaccgagtagtgcatcgcgatctaaaaccac agaacattctggtgaccagcagcggacaaataaaactcgctgacttcggccttgcccgca tctatagtttccagatggctctaacctcagtggtcgtcacgctgtggtacagagcacccg aagtcttgctccagtccagctacgccacccccgtggatctctggagtgttggctgcatat ttgcagaaatgtttcgtagaaagcctctttttcgtggaagttcagatgttgatcaactag gaaaaatcttggacgtgattggactcccaggagaagaagactggcctagagatgttgccc ttcccaggcaggcttttcattcaaaatctgcccaacc

>120_at HG-U95Av2 tgacatcaaatggttaccctg gctgtacccaactggattg ca cttctgagaatgcaa actgcagaccccatatctttgaggatcctttcagtatcaactctggaaagaaaatgacta catcaactgaccatctcaaacgaggcacaattctggactgcaatacatgtaaatttgcta ccatcacatgtaatctcacttcttctgacatcagccaagtcaatgtttcgcttatcttgt ggaaaccaacttt a aaaa ca atttttccagcttaaatct ac a aaggggagaac ttcggagtgaaaatgcatctctggttttaagtagcagcaatcaaaaaagagagcttgcta ttcaaatatccaaagatgggctaccgggcagagtgccattatgggtcatcctgctgagtg cttttgccggattgttgctgttaatgctgctcattttagcactgtggaagattggattct t

>1212_at HG-U95Av2 gccctggagcagatcctacagagcacagcgggca a ac gtgtaggagacgaggtgacc a ggc gatctg gc tggtgcctcaggtggcaaatgc gaaagattcaaggtggatctc accccctaccctaccatcagctccatcaacaagaggc gc ggtcttggaggccttccag gtgtctcacccctgccggcagccagatacacccactgagctgagggcctagctcccaaat cctgccccgttggcacagggccacaggagcagaagctgggtgggctgaagaggcctggaa acgagagtcttaattgaggagatgggagactcgaactctagccctggatctgccttcctg ctgaaacttgttccacctcagtcccc catctgtcacacgcatgtggggtggagtaggga ga gcggggagcagggtgggcaggaa ac gttatctatgtgacggggcagtcgtgaggc tgagatgagaatgcggattaaaatgcctggcgtgctcaccgtaacaccacggggaaggct gtgtgccttttctca ccgcttttgttgtgtgtgactccaaagaatgcccgcgct

>1223_at HG-U95Av2 gcgtgaccgccttctctgagttccgcacctacagcttcccc gc acctcccgcagccgc ca caaccacgcgcccaggttggatacggatggcatccacctcctgagcagcc gc cg tgta gaatccaagagtcgcatgtcagcagaggctgccctgagtcactcctacttccggt ctctgggagagcgtgtgcaccagcttgaagacactgcctccatcttctccctgaaggaga tccagctccagaaggacccaggctaccgaggcttggccttccagcagccaggacgaggga

>1226_at HG-U95Av2 ttatattgataacagcactgactagggaaatgatcagttttttttttatacactgtaatg aaccgctgaatatgaggcatttggc

>1227_g_at HG-U95Av2 aactggaccaccagagaatggacaccatccaggaagaccccagcacagactcaca a gg acgaggatgggtttgagaaggaccccttcccaaatagcagcacagctgccaagtcatttg aggatctcacggaccatccggtcaccagaagtgaaaaggctgcctcctttaaactgcagc gtcagaatcgtgttgacagcaaagaaacagagtgctaatttagttctcagctcttctgac ttaagtgtgcaaaatatttttatagatttgacctacaatcaatcacagcttatattttgt gaagactgggaagtgacttagcagatgctgg ca gt

>1237_at HG-U95Av2 agaccgaggcgcatagagaccgagcacagcccagctgggctaggcccggtgggaaggaga gcgtcgttaatttatttcttattgctcctaattaatatttatatgtatttatgtacgtcc tcctaggtgatgagatgtgtacgtaatatttattttaacttatgcaagggtgtgagatgt tccccctgctgtaaatgcaggtctcttggtatttattgagctttgtgggactggtggaag caggacacctggaactgcggcaaagtaggagaagaaatggggaggactcgggtgggggag gacgtcccggctgggatgaagtctggtggtgggtcgtaagtttaggaggtgactgcatcc tccagcattctcaactccgtctgtctactgtgtgagacttcggcggaccattaggaatga gatccgtgagatccttccatcttcttgaagtcgcctttagggtggctgcgaggtagaggg ttgggggttggtgggctgtcacggagcgactgtcgagatcgcctagtatgttctgtgaac acaaata

>1278 at HG-U95Av2 TIGRSequence

>128_at HG-U95Av2 cctacccatatgtgggacaggaagagagttgtatgtacaacccaacaggcaaggcagcta aatgcagagggtacagagagatccccgaggggaatgagaaagccctgaagagggcagtgg cccgagtgggacctgtctctgtggccat ga gcaagcctgacctccttccagttttaca gcaaaggtgtgtattatgatgaaagctgcaatagcgataatctgaaccatgcggttttgg cagtggga a ggaatccagaagggaaacaagcactggataattaaaaacagctggggag aaaactggggaaacaaaggatatatcctcatggctcgaaataagaacaacgcctgtggca ttgccaacctggc

>129_g_at HG-U95Av2 agactctgtcgac atcgaaagaaaggata gt actcctgtcaaaaatcagggtcagtg tggttcctgttgggcttttagctctgtgggtgccctggagggccaactcaagaagaaaac tggcaaactcttaaatctgagtccccagaacctagtggattgtgtgtctgagaatga gg ctgtggagggggctacatgaccaatgccttccaa a gtgcagaagaa

>1334_s__at HG-ϋ95Av2 a ttattac atgactgc ccccagccctggctctgcaatgggcactgggatgagccgct gtgagcccctggtcctgagggtccccacctgggacccttgagagtatcaggtctcccacg tgggagacaagaaatccctgtttaatatttaaacagcagtgttccccatctgggtccttg cacccctcactctggcctcagccgactgcacagcggcccctgcatccccttggctgtgag gcccctggacaagcagaggtggccagagctgggaggcatggccctggggtcccacgaatt tgctggggaatctcgtttttcttcttaagacttttgggacatggtttgactcccgaacat caccgacgtgtctcctgtttttctgggtggcctcgggacacctgccctgcccccacgagg gtcaggactgtgactctttttagggccaggcaggtgcctggacatttgcct gc ggatg gggactggggatgtgggagggagcagacaggaggaatca gtcaggcctgtgtgtgaaag gaagctccactgtcaccctc

>1369_s_at HG-U95Av2 ttttcctaga attgcacgggagaa atacaaatagcaaaattgggccaagggccaagag aa atccgaactttaatttcaggaattgaatgggtttgc agaatgtgatatttgaagca tcacataaaaa ga gggacaataaattttgccataaagtcaaatttagctggaaatcct ggatttttttctgttaaatctggcaaccctagtctgc agccaggatccacaagtccttg ttccactgtgccttggtttctcctttatttctaagtggaaaaag attagccaccatctt acctcacagtgatgttgtgaggacatgtggaagcactttaagttttt catca aacata

>1370_at HG-U95Av2 cccatctgaggatgtagtcgtcactccagaaagctttggaagagattcatccctcacatg cctggctgggaatgtcagtgcatgtgacgcccc attctctcctcttccaggtccctaga ctgcagggagagtggcaagaatgggcc ca gtgtaccaggacctcc gc tagccttgg gactacaaacagcacgctgccccctccattttctctccaatctggaatcctgacattgaa cccagt gc cagggtcagcccattcttacttccctgggatcaaatcaagaagaagcata tgtcaccatgtccagcttctaccaaaaccagtgaagtgtaagaaacccagactgaactta ccgtgagcgacaaagatgatttaaaagggaagtctagagttcctagtctccctcacagca cagagaagacaaaattagcaaaaccccactacacagtctgcaagattctgaaacattgct ttgaccactcttcctgagttcagtggcactcaacatgagtcaagagcatcctgcttctac catgtggatttgg

>1372_at HG-U95Av2 atcttttggaactcctttgatctcactgttattattaacatttatttattatttttctaa atgtgaaagaaatacataatttagggaaaattggaaaa ataggaaactttaaacgagaa aatgaaacctctcataatcccactgcatagaaataacaagcgttaacattt ca atttt tttctttcagtcatttttgtatttgtggtatatgtatatatgtacctatatgtatttgca tttgaaattttggaatcctgctctatgtacagttttgtattatactttttaaatcttgaa ctttatgaacattttctgaaatcattgattattctacaaaaacatgattttaaacagctg taaaatattctatgatatgaatgttttatgcattatttaagcctgtctctattgttggaa tttcaggtcattt

>1377 at HG-U95Av2 gtccacaagacagaagctgaagtgcatccaaaggtgctcagagagccggcccgcctgaat cattctcgatttaactcgagaccttttcaacttggcttcctttcttggttcataaatgaa ttttagtttggttcacttacagatagtatctagcaatcacaacactggctgagcggatgc atctggggatgaggttgcttactaagctttgccagctgctgctggatcacagctgctttc tgttgtc

>1378_g_at HG-U95Av2 agcccagtgaagaccacctctcaggcccactcgctgcctctctcgcctgcctccacaagg cagcaaatagacgagctccgagacagtgacagtgtctgcgacacgggcgtggagacatcc ttccgcaaactcagctttaccgagtctctgaccagtggtgcctcactgctaactctcaac aaaatgccccatgat atgggcaggaaggacctctagaaggcaaaatttagcctgctgac aatt

>1385_at HG-U95Av2 tgaagcactacaggaggaatgcaccacggcagctctccgccaatttctctcagatttcca cagagactgtttgaatgttttcaaaaccaagtatcacactttaatgtacatgggccgcac cataatgagatgtgagccttgtgcatgtgggggaggagggagagagatgtactttttaaa tcatgttccccctaaacatggctgttaacccactgcatgcagaaacttggatgtcactgc ctgacattcacttccagagaggacc tcccaaatgtggaattgactgcctatgccaagt ccctggaaaaggagcttcagtattgtggggctcataaaacatgaatcaagcaatccagcc tcatgggaagtcctggcacagtttttgtaaagcccttgcacagctggagaaatggcatca ttataagctatgagttgaaatgttctgtcaaatgtgtctcacatctacacgtggcttgga ggcttttatggggccctgtccaggtagaaaagaaatggtatgtagagcttagatttccct attgtgacagagccatggtgtgtttgtaata

>1400_at HG-U95Av2 tctcctgaacctgagtagagacactgctgctgagatgaatgaaacagtagaagtcatctc agaaatgtttgacctccaggagccgacctgcctacagacccgcctggagctgtacaagca gggcctgcggggcagcctcaccaagctcaagggccccttgaccatgatggccagccacta caagcagcactgccctccaaccccggaaacttcctgtgcaacccagattatcacctttga aagtttcaaagagaacctgaaggactttctgcttgtc

>1401_g_at HG-U95Av2 cctgaaggactttctgcttgtcatcccctttgactgctgggagccagtccaggagtgaga ccggccagatgaggctggccaagccggggagctgctctctcatgaaacaagagctagaaa ctcaggatggtcatcttggagggaccaaggggtgggccacagccatggtgggagtggcct ggacctgccctgggccacactgaccctgatacaggcatggcagaagaatgggaatatttt atactgacagaaatcagtaatatttatatatttatatttttaaaatatttatttatttat ttatttaagttcatattccatatttattcaagatgttttaccgtaata

>1402_at HG-U95Av2 ttgcacttatgatttcatgtgcggggatcatctgccgtgcctggatcctgaaatagaggc taaattactcaggaagaacaccctctaaatgggaaagtattctgtactcttagatggatt ctccactcagttgcaacttggacttgtcctcagcagctggtaatcttgctctgcttgaca acatctgagtgcagccgtttgagaagaaaacatctattctctccaaaaatgcacccaact agctctatgtttacaaatggacataggactcaaagtttcagagaccattgcaatgaatcc ccaataattgcagaactaaactcatttataa

>1403_s_at HG-U95Av2 gagcttctgaggcgctgctttgtcaaaaggaagtctctaggttctgagctctggctttgc cttg

>1405_i_at HG-U95Av2 agcttccccaactaaagcctagaagagcttctgaggcgctgctttg

>1433_g_at HG-U95Av2 cctctcagaacatactgattgggaggtgcgtgttcagcagaacctgcacacaggacagcg ggaaaaatcgatgagcgccacctctttaaaaactcacttacgttgtcctttttcactttg aaaagttggaaggactgctgaggcccagtgcatatgcaatgtatagtgtctattatcaca ttaatctcaaagagattcgaatgacggtaagtgttctcatgaagcaggaggcccttgtcg tgggatggcatttggtctcaggcagcaccacactgggtgcgtctccagtcatctgtaaga gcttgctccagattctgatgcatacggctatattggtttatgtagtcagttgcattcatt a

>1451_s_at HG-U95Av2 gttgacttcaggaactgaaacatcagcacaaagaagcaatcatcaaataattctgaacac aaatttaatatttttttttctgaatgagaaacatgagggaaattgtggagttagcctcct gtggtaaaggaattgaagaaaata aacaccttacaccctttttcatcttgacattaaaa gttctggctaactttggaatccattagagaaaaatccttgtcaccagattcattacaatt caaatcgaagagttgtgaactgttatcccattgaaaagaccgagccttgtatgtatgtta tggatacataaaatgcacgcaagccat atctctccatgggaagctaagttataaaaata ggtgcttggtgtacaaaactttttatatcaaaaggctttgcacatttctatatgagtggg tttactggtaaattatgttattttttacaactaattttgtactctcagaatgtttgtcat atgcttcttgcaatgcata

>1457_at HG-U95Av2 caaacagcagctaaaatatgccgttcagatttgtaaggggatggactatttgggttctcg gcaatacgttcaccgggacttggcagcaagaaatgtccttgttgagagtgaacaccaagt gaaaattggagacttcggtttaaccaaagcaattgaaaccgataaggagtattacaccgt caaggatgaccgggacagccctgtgttttggtatgctccagaatgtttaatgcaatctaa attttatattgcctctgacgtctggtcttttggagtcactctgcatgagctgctgactta ctgtgattcagattctagtcccatggctttgttcctgaaaatgataggcccaacccatgg ccagatgacagtcacaagacttgtgaatacgttaaaagaaggaaaacgcctgccgtgccc acctaactgtccagatgaggtttatcagcttatgagaaaatgctgggaattccaaccatc caatcggacaagctttcagaaccttattgaaggatttgaagca

>1461_at HG-U95Av2 tcagatgctgccagagagtgaggatgaggagagctatgacacagagtcagagttcacgga gttcacagaggacgagctgccctatgatgactgtgtgtttggaggccagcgtctgacgtt atgagtgcaaaggggctgaaagaacatggacttgtatatttgtacaaaaaaaaagtttta tttttctaaaaaaagaaaaaagaagaaaaaatttaaagggtgtact a atccacactgc acactgcctagcccaaaacgtcttattgtggtaggatcagccctcattttgttgcttttg tgaactttttgtaggggacgagaaagatcattgaaattctgagaaaacttcttttaaacc tcacctttgtggggtttttggagaaggttatcaaaaatttcatggaaggaccacatttta tatttattgtgcttcgagtgactgaccccagtggtatcctgtgacatgtaacagccagga gtgttaagcgttcagtgatgtggggtgaaaagttactacctgtcaaggtttgtgttaccc tcctgtaaatggtgtacataatgtattgttggtaatt

>1520_s_at HG-U95Av2 acttcaccatgcaatttgtgtcttcctaaagagagctgtacccagagagtcctgtgctga atgtggactcaatccctagggctggcagaaagggaacagaaaggtttttgagtacggcta tagcctggactttcctgttgtctacaccaatgcccaactgcctgccttagggtagtgcta agaggatctcctgtccatcagccaggacagtcagctctctcctttcagggccaatcccca gcccttttgttgagccaggcctctctcacctctcctactcacttaaagcccgcctgacag aaaccacggccacatttggttctaagaaaccctctgtcattcgctcccacattctgatga gcaaccgcttccctatttatttatttatttgtttgtttgttttgattcattggtctaatt ta tcaaagggggcaagaagtagcagtgtctgtaaaagagcctagtttttaatagctatg gaatcaattcaatttggactggtgtgctctctttaaatcaagtcctttaattaagactga aaatatataagctcagattatttaaatgggaatatttataaatgagcaaatatcatactg ttcaatggttc

>1561_at HG-U95Av2 gtgctgtttgcgcccttcggccgggcgggcgccccgggaccaggcggcggcagcgacctg cggcggcgggaggcagcgagggctgagccccgggacgcgcggaccggctggcccgaggag ccggccccggagacgcagttcaagcgccgcagctgccagatggagttcgaggagggcatg gtggaggggcgcgcgcgcggcgaggagctggccgccctgggcaagcaggcgagcttctcg ggcagcgtggaggtcatcgaggtgtcctgacccctccgctgccctcggccccgccgcccg cagccaggcccgt ataaatg atat a

>1562_g_at HG-U95Av2 tatttaagctgttcattctggcaatgatttggcaacagtgcgggtggtcctcgagctcta tttttactgtctggtatttaaactgaaacatacgtttctaagcaatacgaggccaccttc agtcgcaagctgggtgccaggcctggggccctcccagttcccccgccccaggaaacactg ctgacctttgcaaaggctgccgagctttcgtg

>1573_at HG-U95Av2 aaggacattgtatgcagggagcactgttcacatcatagataaagctgatttgtatattta tta gacaatttctggcagatgtaggtaaagaggaaaaggatccttttcctaattcacac aaagactccttgtggactggctgtgcccctgatgcagcctgtggctggagtggccaaata ggagggagactgtggtaggggcagggaggcaacactgctgtccacatgacctccatttcc caaagtcctctgctccagcaactgcccttccaggtgggtgtgggacacctgggagaaggt ctccaagggagggtgcagccctcttgcccgcacccctccctgcttgcacacttccccatc tttgatccttctgagctccacctctggtggctcctcctaggaaaccagctcgtgggctgg gaatgggggagagaagggaaaagatccccaagaccccctggggtgggatctgagctccca cctcccttcccacctactgcactttcccccttcccgccttccaaaacctgcttccttcag t

>1577_at HG-U95Av2 catggaattctatttgctgggctttttttttctctttctctcctttctttttcttcttcc ctccctatctaaccctcccatggcaccttcagactttgcttcccattgtggctcctatct gtgttttgaatggtgttgtatgcctttaaatctgtgatgatcctcatatggcccagtgtc aagttgtgc tgtttacagcactac ctgtgccagccacacaaacgtttacttatcttat gccacgg

>158_at HG-U95Av2 gcaccaaaattacttttccaagagaaggagatgaaaacaccaaatagtattccagcagac attgtttttatcattaaagacaaagatcatccaaaatttaaaagggatggatcaaatata atttactgctaaaattagtttacgagaggagattgtgtggcgtgctcaattaatgtacca acactggatggaagaacataccta gtcagtaaatgatattgtgaacccggaatgaggag aagaattattggatatgggctgccatttccaaaaaatcctgaccaacgtggtgaccttct aatagaatttgaggtgtccttcccagat ctata cttcttcatggaaagaagtactaga catctccgcctcatagaatgagacttgtaga

>1591_s_at HG-U95Av2 ggacgtttccatcaggttccatcccgaaaatctctcggttccacgtccccctggggcttc tcctgacccagtccccgtgccccgcctccccgaaacaggctactctcctcggccccctcc atcgggctgaggaagcacagcagcatcttcaaacatgtacaaaatcgattggctttaaac a

>159_at HG-U95Av2 gtactgttttccagttcatcgattttctattatggaaaactgtgttgccacagtagaact gtctgtgaacagagagacccttgtgggtccatgctaacaaagacaaaagtctgtctttcc tgaaccatgtggataactttacagaaatggactggagctcatctgcaaaaggcctcttgt aaagactggttttctgccaatgaccaaacagccaagattttcctcttgtgatttctttaa aagaatgactatataatttatttccactaaaaatattgtttctgcattcatttttatagc aacaacaattggtaaaactcactgtgatcaa

>1633_g_at HG-U95Av2 tgttatcccaagtgctct attctggtgagaagaaccttaattccataatttgggaagga atggaagatggacaccaccggacaccaccagacaataggatgggatggatggttttttgg gggatgggctaggggaaataaggcttgctgtttgttttcctggggcgctccctccaattt tgcagatttttgcaacctcctcctgagccgggattgtccaattactaaaatgtaaataat cacgtattgtggggaggggagttccaagtgtgccctccttttttttcctgcctggattat ttaaaaagccatgtgtggaaacccactatttaa

>1637_at HG-U95Av2 tgacaaaagccagcatactttccctgcacccatctgctcaccagatctcaggcaggaaag cccctctctgttgaagtcaggggctatcttttggtatacttgtgtgaaagtggctggttg ggagcagagctaagtggcttcccattaacctgaggtctctttctttactctgggtcagac ctgaggttggggaaggcgactgagccatgctcagaatgtctggtcctggcttgggcctga gtagggcagagagggcctttcatggctgatcagagcttaccagccccaccccaccatggt agccttagggtgctgagtgcctgatactgcctgacaagtgcctgacacgcagcctagttc cttcctggcccctctctcactggctgggaaaccctagaccatgtcagataggacaacact gc gggttttacatccagatagtaa

>1652_at HG-U95Av2 caccacacaaacttagttcatatgcttttacttgggcaagggtgctttccttccaatacc ccagtagcttttattttagtaaagggaccctttcccctagcctagggtcccatattgggt caagctgcttacctgcctcagcccaggattttttattttgggggaggtaatgccctgttg ttaccccaaggcttct

>1664_at HG-U95Av2 TIGRSequence

>1669_at HG-U95Av2 tcagcccactacatagatagctttttttttttttttttttttttaataaggacacctctt tccaaacaggccatcaaatatgttcttatctcagacttacgttgttttaaaagtttggaa agatacacatcttttcatacccccccttaggaggttgggctttcatatcacctcagccaa ctgtggctcttaatttattgcataatga atccacatcagccaactgtggctctttaatt tattgcataatgatattcacatcccctcagttgcagtgaattgtgagcaaaagatcttga aagcaaaaagcactaattagtttaaaatgtcacttttttggtttttattatacaaaaacc atgaagtactttttttatttgctaaatcagattgttcctttttagtgactcatgtt a g aagagagttgagtttaacaatcctagcttttaaaagaaactatttaatgtaaaatattct acatgtcattcagatattatgta atcttctagcctttattctgtacttttaatgtacat atttctgtcttgcgtgatt

>1674_at HG-U95Av2 gaagatggacttcatgcaagttggcagtggttctggtactaaaaattgtggttgtttttt ctgtttacgtaacc gcttagtattgacactctctaccaagagggtcttcctaagaagag tgctgtcattatttcctcttatcaacaacttgtgacatgagattttttaagggctttatg tgaactatgatattgtaatttttctaagcatattcaaaagggtgacaaaattacgtttat gtac aaatctaatcaggaaagtaaggcaggaaaagttgatggtattcattaggttttaa ctgaatggagcagttcctt tataataacaattgtatagtagggataaaacactaacaat gtgtattcattttaaattgttctgtatttttaaattgccaagaaaaacaactttgtaaat ttggagatattttccaacagcttttcgtcttcagtgtcttaatgtggaagttaac

>1717_s_at HG-U95Av2 atatatg atctaaaccatatgaacatatattttttagaaactaagagaatgataggctt ttgttcttatgaacgaaaaagaggtagcactacaaacacaatattcaatccaaatttcag cat attgaaattgtaagtgaagtaaaacttaagatatttgagttaacctttaagaattt taaatattttggcattgtactaataccgggaacatgaagccaggtgtggtggtatgtacc tgtagtcccaggctgaggcaagagaattacttgagcccaggagtttgaatccatcctggg cagcatactgagaccctgcctttaaaaacnaacagnaccaaanccaaacaccagggacac atttctctgtcttttttgatcagtgtcctatacatcgaaggtgtgcat tatgttg

>1737_s_at HG-U95Av2 aagagacatgtaccttgaccatcgtccttcctctcaagctagccagagggtgggagccta aggaagcgtggggtagcagatggagtaatggtcacgaggtccagacccactcccaaagct cagacttgccaggctccctttctcttcttccccaggtccttcctttaggtctggttgttg caccatctgcttggttggctggcagctgagagccctgctgtgggagagcgaagggggtca aaggaagacttgaagcacagagggctagggaggtggggtacatttctctgagcagtcagg gtgggaagaaagaatgcaagagtggactgaatgtgcctaatggagaagacccacgtgcta ggggatgaggggcttcctgggtcctgttccctaccccatttgtggtcacagccatgaagt caccgggatgaacctatccttccagtggctcgctccctgtagctctgcctccctctccat a ctccttcccctacacctccctccccacacctccctactcccctgggcatcttctggct tgactggatggaagga

>1761_at HG-U95Av2 gaggttgatccacagaggactgggacacaccacgagaatctcccagagtgtcattacagt ggaagacttcgagacgattgatgcaggatattacatttgcactgctcagaatcttcaagg acagaccacagtagctaccactgttgagttttcctgacttggaaaaggaaatgtaatgaa cttatggaaagcccatttgtgtacacagtcagctttggggttccttttattagtgctttg ccagaggctgatgtcaagcaccacaccccaaccccagcgtctcgtgagtccgacccagac atccaaactaaaaggaagtcatccagtctattcacagaagtgttaacttttctaacagaa agcatgattttgat gcttacctac >1778_g_at HG-U95Av2 cagtgggcagtcagaggcaagaagcagaggggaggagcaagggtgccagggagatgggga tgctggggtcaaagccagccccagggacattcgggaacagtctgagacaactgctgaagg gggccagggtcaagcccaggaaggccctgctcagccaggggaaccagaggcagagggaag ccgggcagcagaggagtagcttgaagtggccagaagggtcattcggggcgggagaccctg agcctgctgagaaatccttttagcgccagcaagccccacccagggccctgtcctgtgtct gccaccacctttgtctgatacttgtttccagggaagctgggggaactgccacatctgagg aactggaataa >1788_s_at HG-U95Av2 agtgatgaaacccacagatcctagcaaatgtgcccaaccagctttactaaagggggagga agggagggcaaagggatgagaagacaagtttcccagaagtgcctggttctgtgtacttgt ccctttgttgtcgtcgttgtagttaaaggaatttcattttttaaaagaaatcttcgaagg tgtggttttcatttctcagtcaccaacagatgaataat atgcttaataataaagtattt attaagactttcttcagagtatgaaagtacaaaaagtctagttacagtggatttagaata tatttatgttgatgtcaaacagctgagcaccgtagcatgcagatgtcaaggcagttagga agtaaatcggtgtcttgtagatatgtgcaaggtagcatgatgagcaacttgagtttgttg ccactgagaagcaggcg >1798_at HG-U95Av2. tagtttatgtatcaccagactgggttattgccaagttatatatcaccaaaagctgtatga ctggatgttctggttacctggtttacaaaattatcagagtagtaaaactt gat tatat gaggatattaaaactacactaag atcatttgattcgattcagaaagtactttgatatct ctcagtgcttcagtgctatcattgtgagcaattgtctttatatacggtac gtagcca ctaggcctgtctgtggcattctctagatgtttcttttttacacaataaattcctt tatc agcttga >1845_at HG-U95Av2 agacattgctctatgtctgccttcgaccacagcaagccatcatcctccattgctcccggg gactcaagaggaatctgtttctctgctgtcaacttcccatctggctcagcatagggtcac tttgccattatgcaaatggagataaaagcaattctggctgtccaggagctaatctgaccg ttctattgtgtggatgaccacataagaaggcaattttagtgtattaatcatagattatta taaactataaacttaagggcaaggagtttattacaatgtatctttattaaaacaaaaggg tgtatagtgttcacaaactgtgaaaatagtg >1867_at HG-U95Av2 taacaccctatgcccattgtcctgatctgaaaattcttggaaattgttccatgtgattaa catggaactgcctctacttaatcattctgaatgattaaatcgtttcattttctaaatgtg ttataatgtgtttagccctttcttgttgctgtatgtttaga gctttccaatcttttgtt actactaataatg >1868_g_at HG-U95Av2 atttgacc gctcaaacgtatcttgaagatggacagaaaagctgtggagacccacctgct caggaaccctcaccttgtttcggactatagagtgctgatggcagagattggtgaggattt ggataaatctgatgtgtcctcattaattttcctcatgaaggattacatgggccgaggcaa •gataagcaaggagaagatttcttgggaccttgtggttgagttggagaaactaaatctggt tgccccagatcaactggatttattagaaaaatgcctaaagaacatccacagaatagacct gaagacaaaaatccagaagtacaagcagtctgttcaaggagcagggacaagttacaggaa tgttctccaagcagcaatccaaaagagtctcaaggatccttcaaataa

>1877_g_at HG-U95Av2 TIGRSequence >1897_at HG-U95Av2 ggaaccacagatttgtgcccattcctaatattttgttctgcaaattaatgtataatttga ggtgaaattcagttataaagtcaaggacgaatttgcacagtgatatatttctatgtgtat gcaagtacaagtatataatatgtcacctggcacattcattttctcagttgaagaagagaa aatttgaaaatgtccttatgcttttagagttgcaacttaagtatatttggtagggtgagt gtttccactcaaaata gtcaacttaaaaaaaaataggccctt cataaaaaccaaactg tagcaagatgcaaatgcatggcaaatctgtcggtctccagttggttatctgaatagtgtc accaattccaccaagacagtgctgagattggaaagggcactcatttggattgccttactt ctcttgccttaaatatatcccatatatttaatatgtcaaaaagggcttgaggtgaatttc attaaatggaataatatgatgccactttgcagctaaaataagc

>1951_at HG-U95Av2 tcaaggccacaaccatgatgatccgaccagcagatttctaaacatcccagtccacctgag gaactgtctcgaactattttcaaagacttaagcccagtgcactgaaagtcacggctgcgc actgtgtcctcttccaccacagagggcgtgtgctcgg gctgacgggacccacatgctcc agattagagcctgtaaactttatcacttaaacttgcatcacttaacggaccaaagcaaga ccctaaacatccataattgtgattagacagaacacctatgcaaagatgaacccgaggctg agaatcagactgacagtttacagacgctgc gtcacaaccaagaatgttatgtgcaagtt tatcagtaaataactggaaaacagaacacttatgttatacaatacaga catcttggaac tgcattcttctgagcactgtttatacactgt

>1968_g_at HG-U95Av2 ctatggattaagccggtcccaacctgtcatgaaagttgcagtgaagatgctaaaacccac ggccagatccagtgaaaaacaagctctcatgtctgaactgaagataatgactcacctggg gccacatttgaacattgtaaacttgctgggagcctgcaccaagtcaggccccatttacat catcacagagtattgcttctatggagatttggtcaactatttgcataagaatagggatag cttcctgagccaccacccagagaagccaaagaaagagctggatatctttggattgaaccc tgctgatgaaagcacacggagctatgttattttatcttttgaaaacaatggtgactacat ggacatgaagcaggctgatac acacagtatgtccccatgctagaaaggaaagaggtttc taaatattccgacatccagagatcactctatgatcgtccag

>1987_at HG-U95Av2 agaggaacctgagtcatgctcaggcccaagccctgttggcaggcagaccactgct tctg gccttccgtgactatctgaaaaaaatcgtgaatggctagagctactcttcacttgctgaa cattttcaaaaagaattgacacttgctgaacatttcttttcaattcagaacttctgatgg attaaattgccttcttcctcgaaaaccctgggacccttccagatgggactaactggggaa agtggacaagttacaaacaaagaaactcaaaggaaagtcattggcactgatctctaagat gctatcacatgtgattggtggttga

>2002_s_at HG-U95Av2 ctacagataccacaacctggatcaggtccaagcaaaacgtccagagtgctacaaaatgtt gcgttctcagtccaaaaagaagtggaaaagaatctgaagtcatgcttggacaatgttaat gttgtgtccgtagacactgccagaacactattcaaccaagtgatggaaaaggagtttgaa gacggcatcattaactggggaagaattgtaaccatatttgcatttgaaggtattctcatc aagaaacttctacgacagcaaattgccccggatgtggatacctataaggagatttcatat tttgttgcggagttcataatgaa

>2014_s_at HG-U95Av2 ccatccttcgatttccctatgattcatggggaactccatttcagcagctcaaacaggtgg tagaggagccatcgccacaactcccagcagacaagttctctgcagagtttgttgacttta cctcacagtgcttaaagaagaattccaaagaacggcctacatacccagagctaatgcaac atccatttttcaccctacatgaatccaaaggaacagatgtggcatcttttgtaaaactga ttcttggagactaaaaagcagtggacttaatcggttgaccctactgtggattggtgggtt tcggggtgaagcaagttcactacagcatcaatagaaagtcatctttgagataatttaacc ctgcctctcagagggttttctctcccaattttctttttactccccctcttaagggggcct tggaatctatagtata

>2018_at HG-U95Av2 tcagcttgagtgctgtttacacttgcaaaagagatccctgcccacatcaggtggactgtt tcctctctcgccccacggagaaaaccatcttcatca cttcatgctggtggtgtccttgg tgtccctggccttgaatatcattgaactcttctatgttttcttcaagggcgttaaggatc gggttaagggaaagagcgacccttaccatgcgaccagtggtgcgctgagccctgccaaag actgtgggtctcaaaaatatgcttatttcaatggctgctcctcaccaaccgctcccctct cgcctatgtctcctcctgggtacaagctggttactggcgacagaaacaattcttcttgcc gcaattacaacaagcaagcaagtgagcaaaactgggctaattacagtgcagaacaaaatc gaatggggcaggcgggaagcaccatctctaactcccatgcacagccttttgatttccccg atga aaccagaattctaaaaaactagctgctggacatgaattacagccactagccattg tggaccagcgaccttcaagcagagccagcagtcgtgccagcagcagacctcggcc

>2024_s_at HG-U95Av2 agtttgctggatttcctgaagagcgatgaaggtggcaaagtgctgcttccaaagctcatt gacttttctgctcagattgcagagggaatggcatacatcgagcggaagaactacattcac cgggacctgcgagcagctaatgttctggtctccgagtcactaatgtgcaaaattgcagat tttggccttgctagagtaattgaagataatgagtacacagcaagggaaggtgctaagttc cctattaagtggacggctccagaagcaatcaactttggatgtttcactattaagtctgat gtgtggtcctttggaatcctcctatacgaaattgtcacctatgggaaaattccctaccca gggagaactaatgccgacgtgatgaccgccctgtcccagggctacaggatgccccgtgtg gagaactgcccagatgagctctatgacattatgaaaatgtgctggaaagaaaaggcagaa gagagaccaacgtttgactacttacagagcgtcctggatgatttctacacagccacggaa gggcaatacc

>2036_s_at HG-U95Av2 gagctgggacacttaacagatgcaatgtgctactgattgtttcattgcgaatctttttta gcataaaattttct ctctttttgttttttgtgttttgttctttaaagtcaggtccaatt tgtaaaaacagcattgctttgtaaattagggcccaattaataatcagcaagaatttgatc gttcagttccacttggaggccttcatcctcgggtgtgctatggatggcttct

>2049_s_at HG-U95Av2 aagccctggacgatctgcacaagatgaaccacgtgacaccccccaacgtgtccctgggcg ctaccggggggcccccggctgggcccgggggcgtctacgccggcccggagccacctcccg tttacaccaacctcagcagctactccccagcctctgcgtcctcgggaggcgccggggctg ccgtcgggaccgggagctcgtacccgacgaccaccatcagctacctcccacacgcgccgc ccttcgccggtggccacccggcgcagctgggcttgggccgcggcgcctccaccttcaagg aggaaccgcagaccgtgccggaggcgcgcagccgggacgccacgccgccggtgtccccca tcaacatggaagaccaagagcgcatcaaagtggagcgcaagcggctgcggaaccggctgg cggccaccaagtgccggaagcggaagctggagcgcatcgcgcgcctggaggacaaggtga agacgctcaaggccgagaacgcggggctgtcgagtaccgccggcctcctccgggagcagg tggcccagctcaaacagaaggtcatgacccacgtcagcaacggctgtcagctgctgcttg gg

>204_at HG-U95Av2 agatcttaaccagtttctatcccttacctgcttttctcttctcttctcctgctccgttcc tcatccacccctccccatctggaccataatagggacaccaaaacaaacccaaattggtaa aaagaataatcaaaaagaagacattatccggttaagagtctgtgctggttgccacnnaag agagaacagttgtccaggatgctggctggtggaacaacctgctggcccgaaacaaggctg ccaggtgtggaacagcccatgc

>205_g_at HG-U95Av2 acagcccatgctgactggggacatacacttgcatctttgttgaaagcagaagaagacaga ccctttccccaccttccttacctcctcttcccccattaaggcagctcatccaagcttgta tttaactgaataaatgagtagacattgtggacctcacaagattatttaattcttaagatg tgtagaccttgatggtaggtgtgacatgttagtttttcttacttgcatttatttaagaca cactgttacagagatactgttgtcaccttctggggcacggtctttggggagaggggagtg catttagactta gtggaacctgtacaaattgtgatgtggctacatagaaa

>2073_s_at HG-U95Av2 ccacagctgtgctggaccgtgagtccccatttgtcgacaacagcgtgtacactgctctct tcctggcaattgacagtggcaaccctcccgctacgggcactgggactt gctgataaccc tggaggacgtgaatgacaatgccccgttcatttaccccacagtagctgaagtctgtgatg atgccaaaaacctcagtgtagtcattttgggagcatcagataaggatcttcacccgaata cagatcctttcaaatttgaaatccacaaacaagctgttcctgataaagtctggaagatct ccaagatcaacaatacacacgccctggtaagccttcttcaaaatctgaacaaagcaaact acaacctgccca catggtgacagattcagggaaaccacccatgacgaatatcacagatc tcagggtacaagtgtgctcctgcaggaattccaaagtggactgcaacgcggcgggggccc tgcgcttcagcctgccctcagtcctgctcctcagcctcttcagcttagcttgtctgtgag aactcctgacgtctgaagct

>215_g_at HG-U95Av2 ggcgcccgtgggactctacacggcccatgtgggctacagcatgtaccacctgacatagag ggtcccaggtccccacctgtgggccagccgattcctccagccctggtgc gtacccccga cgtgctcccctgctcggcaccgccagccgccttccctttaaccctcacac gctccagtt tcacctctttgc ccctgagttcactctccgaagtc gatccctgccaaaaagtggctgg aagagtcccttagtactcttctagcatt

>231_at HG-U95Av2 acctcaccattgtgaagcacctac atgtgctgggtgcctcccacact gctggggctca cggggcctccaacccatttaatcaccatgggaaactgttgtgggcgctgct ccaggata- aggagactgaggcttagagagaggaggcagccccctccacaccagtggcctcgtggttat aagcaaggctgggtaatgtgaaggcccaagagcagagtctgggcctctgactctgagtcc actgctccatttataaccccagcctgacctgagactgtcgcagaggctgtctggggcctt tatcaaaaaaagactcagccaagacaaggaggtagagaggggactgggggactgggagtc agagccctggctgggttcaggtcccacgtctggccagcgactgccttctcctctctgggc ctttgtttccttgttggtcagaggagtgattgaacctgctcatctccaaggatcctctcc a

>257_at HG-U95Av2 tagcaacagtcatttctgaaaatatgttggatagaaagtcactctttggcaaaagtgtta gaatttgcttttgtgccatctattccttttatggcatctatcttgaaagtaatcttgtat tggagattgaaagatgctgtaatttagaaattaacatgatatcttaaattacctttatga aatatagttttgtataatagcatagattttccttcaaaaaatgaacatttatata ctac aaaaatatggagaagagcaatttgaaagcctactttctgaagaaaatggtgggatttttt tttatcatgattaaatatcaaaaaattgcccta gaaaactttaaatctctaaaacattt gaaatac accatat tgtgatttattgagaataaaaatccattttgaaatgtaaaattt ttatgatctgattcagttttaagaa

>265_s_at HG-U95Av2 atgtctaatagttattccctatttgttttcttctgtatgttaggg gctctggaagagag gaatgcctgtgtgagcaagcatttatgtttatttataagcagatttaacaattccaaagg aatctccagttttcagttgatcactggcaatgaaaaattctcagtcagtaattgccaaag ctgctctagccttgaggagtgtgagaatcaaaactctcctacacttccattaacttagca tgtgttgaaaaaaaaagtttcagagaagttctggctgaacactggcaacgacaaagccaa cagtcaaaacagagatgtga aaggatcagaacagcagaggttcttttaaaggggcagaa aaactctgggaaataagagagaacaactactgtgatcaggctatgtatggaatacagtgt ta tttctttgaaattgtttaagtgttgtaaatatttatgtaaactgcattagaaattag ctgtgtgaaataccagtgtggtttgtgtttgagttttattgagaattttaaatta aact taaaatattttataatttttaaagtatatatttatttaagcttatgtcagacctatttga cataacactataaa

>286_at HG-U95Av2 tcgccaggcaggagtttctctcggtgactactatcgctgtcatgtctggtcgtggcaagc aaggaggcaaggcccgcgccaaggccaagtcgcgctcgtcccgcgctggccttcagttcc cggtagggcgagtgcatcgcttgctgcgcaaaggcaactacgcggagcgagtgggggccg gcgcgcccgtctacatggctgcggtcctcgagtatctgaccgccgagatcctggagctgg cgggcaacgcggctcgggacaacaagaagacgcgcatcatccctcgtcacctccagctgg ccatccgcaacgacgaggaactgaacaagctgctgggcaaagtcaccatcgcccagggcg gcgtcttgcctaacatccaggccgtactgctccctaagaagacggagagtcaccacaagg caaagggcaagtgaggctgacgtccggcccaagtgggcccagcccggcccgcgtctcgaa ggggcacctgtgaactcaaaaggctctt

>287_at HG-U95Av2 gttaacacaaaatccatgggcagcatgatggcaggtcctctgttgcaaactcagttccaa agtcacaggaagaaagcagaaagttcaacttccaaagggttaggactctccactcaatgt cttaggtcaggagttgtgtctaggctggaagagccaaagaaatattccattttcctttcc ttgtggttgaaaccacagtcagtggagagatgtttggaacacagtcagtggagctggtgg taccaggtttagcattattggatgtcaaaagcattttttttgtcatgtagctgttttaag aaatctggcccagggtgtttgcagctgtgagaagtcactcacactggccacaaggacgct ggctactgtctattaaaattctgatgtttctgtgaaattctcagagtgtttaatt

>31472_s_at HG-U95Av2 gacaagttttggtggcacgcagcctggggactctgcctcgtgccgctgagcctggcgcag atcgatttgaatatnnrinnnnnnnnnrinnrinnnnnattccacgtggagaaaaatggtcgc tacagcatctctcggacggaggccgctgacctctgcaaggctttcaatagcaccttgccc acaatggcccagatggagaaagctctgagcatcggatttgagacctgcagtttgcattgc agtcaacagtcgaagaaggtgtgggcagaagaaaaagctagtgatcaacagtggcaatgg agctgtggaggacagaaagccaagtggactcaacggagaggccagcaagtctcaggaaat ggtgcatttggtgaacaaggagtcgtcagaaactccagaccagtttatgacagctgatga gacaaggaacc

>31540_at HG-U95Av2 atgagaccagtacaaactactcaagaggaagatggctgtagctnnnnnnnnnnnnnnnaa gaagaaggaggatgtgaactgtgaaatggaagtcaatagggctgttgggactttcttgaa aagaagcaaggaaata gagtcatccgctatcacagctttcaaaagcaagaacaccatcc tacataatacccaggattcccccaacacacgttcttttctaaatgccaatgagttggcct ttaaaaatgcaccacnnnnnnnnrinnnnnnnnnnnnnnririnnnnnnnnnrinnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntgccaggcccg gccaaaataatgcaccacttttaacagaacagacag

>31622_f_at HG-U95Av2 gtgtctcctgcacctgcgctggttcctgcaagtgcaaagagtgcaaatgcacctcctgca agaagagctgctgctcctgctgccccgtgggctgtagcaagtgtgcccagggctgtgttt gcaaag

>31697_s_at HG-U95Av2 caaactggccactgacaaaaatgaccccnnnnnnnnnnnnnnnnnnnnnnnacattacct gaatgagcaggtgaaagccatcaaagaattgggtgaacgtgaccaannnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnagctgtggggtgacttccctggtca ccaaggcagtgcatgcatgttggggtttcctttacctt

>31803_at HG-U95Av2 aagtgggctgtggtgcccatttgcagtgactgtgaagtgactccaggacggacctgcggg ggcaccnagaggtcctaagccccaggactgagggtcgtgcatcaccactcgggtgtcccg ggaggtgccctgggcccggggacctcacaggcaggacggcgacactaatgcagggagagg gagtctggccccagcttttcctatcagaggcgattttccttcaccaggggatgggcagga aagaggcaggggccccagaagcttctgtccctcatgcctgagggcacgggggacacttgg annnnnnnnnnnnnnnngtgcgtccaaggccatgctctctgcgggtcagtgcctgagtct cgcctccctgctggtccctgaagccccctcannnnnnnnnnnnnnnnnnrinnnnnnrinnn nnnnnnnnnnnnnnnnnnnnnnnccctctcagcccaacatcagcttcctctttctccctt gctgtagacaggctggat

>31825_at HG-U95Av2 gaaacgaccaagaagagaggcttgttggaatcaattctnnnnnnnnnnnnnnnnnnnnnn nnnntagaagtcantgtaactgtagtgtgtctgctngttacctagagggtctnacctncc enactcttcacagcaaacctgnagcagcgcgtncctaagcancctncccgctccnggtga nccccatccttgcanancctgactctgtcactcaagcctttctnccanccaggcccctca tctgaatanccaagcacagaaatgagtggtgtgactaattccttacctctcccaaggagg gtacacaactagcaccattct gatgtnccagggaagaagccacctcaagacatatgagg ggtgccctgggctaatgttagggcttaattttctcaaagcctgacctttcaaatccannn nnnnnnnnnnnnnnccctcctgctgttgcctccctgtgacctggaggacagtgtgtgcca tgtctccca ac agagataaataaatgtagccacattt ctgtnaaaaaaaaaaaaaaa aaactcgaggggggccggtacccaattcgcccta agctgagtcgt

>31862_at HG-U95Av2 acatcccctcagttgcagtgaattgtgagcaaaagatcttgaaagcaaaaagcactaatt agtttaaaatgtcacttttttggtttttattatacaaaaaccatgaagtactttttttat ttgctaaatcagattgttcctttttagtgactcatgtttatgaagagagttgagtttaac aatcctagcttttaaaagaaactatttaatgtaaaatattctacatgtcattcagatatt atgtatatcttctagcctttattctgtacttttaatgtacatatttctgtcttgcgtgat ttgtatatttcactggtttaaaaaacaaacatcgaaaggcttatgccaaatggaagatag aatataaaataaaacgttacttgtatannnnnaannnnnnnnaannnnnnnncagataat tcatgtggagatttttggagaaaccatgacggatagtttaggatgactacatgtcaaagt aataaaagagtggtgaattttaccaaaaccaagctatttggaagc

>31895_at HG-U95Av2 agtcttggttctccatctgtaattttttttaacagtttgcta agcttactgcttaacta attttaaataaggaaataagtatgttagatgcagtagacgatacaggttgcatgtggaca ctcagtcacattaacaacttgggaaaaaaatggcaatgttacggtgaattctcaggtgaa cttttttcagtta

>31974_at HG-U95Av2 cagcggcatgaagtttgagattggccaggccctgtacctgggcttcatctcctncgtccc tctcgctcattggtggcaccctgctttgcctgtcctgccaggacgaggcaccctacnngc cctannccaggccccgcccagggccaccacgaccactgcaaacaccgcacctgcctacca gccaccagctgcctacaaagacaatcgggccccctnagtgacctcggccanncacagcgg gtacaggctgaacgactacgtgtgagtccccacagcctgcttctcccctgggctgctgtg ggctggttcccggcgggactgtcaatggaggcaggggtnnnnnnnnnnnnnnnnnnnnnn nncaatttttg a ccaaggaaataatgtgaatgcgaggaaatgtctttagagcacaggg aca

>32034__at HG-U95Av2 cctgttcacaagctgagccatatgtacataatctagattttgttttcatagttttgcact tttatagcctatttttgaagattaacacatttgcaagatgattgactcaatctttgccta atccaatgagtgttacagagagcttgctgtgactagaaccataaatcttaaagggggtat gtgataatagagggctggaatttaaacctgtatttaaaaaaaagaatcaccaaatctatt tgaaaacaagtcgatttgtattatgctggaattttttgggctttcagatttctcttttta accacatttctgaatgtataaaaataccaattattttcctacagccctttgtacttcaaa atatgtttttgtgtccatcagtattaactattg

>32052_at HG-U95Av2 gctcgctttcttgctgtccaatttctattaaaggttcctttgttccctaagtccaactac taaactgggggatattatgaagggccttgagcatctggattctgcctaataaaa

>32114_s_at HG-U95Av2 agcttgggcacagcagactggcctggccctgagactggggagtggctncnacagncctcc tgccacccacacaccactctccctagactctncctagggttcaggagctgctgggcccag aggtgacatttgacnttttttccaggaaaaatgtaagtgtgaggaaaccctttttatttt attacctttcactctctggctgctgggtctgccgtcggtcctgctnnnnnnnnnnnnnnn ngagcctctgcccggggagcctcaggcagtcctctcctgctgtcacagctgccatccact tctcagtcccagggccatctcttggagtgacaaagctgggatcaaggacagggagttgta acagagcagtgccagagcatgggcccaggtcccaggggagaggttggggctggcaggcca ctggcatgtgctgagtagcgcagagctacccagtgagaggccttgtctaactgcctttc

>32115_r_at HG-U95Av2 ggtctgccgtcggtcctgctgctaacctggcagcagagcctctgcccggggagcc

>32168_s_at HG-U95Av2 aacctacctgtgaatcatatgttgtaggaaaagctgttcccatgtctaacaggacttgaa ttcaaagcatgtcaagtggatagtagatctgtggcgatatgagagggatgcagtgccttt ccccnattcattcctgatggaattgttatactaggttaacatttgtaatttttttctagt tgtaatgtgtatgtctggtaaataggtattatattttggccttacaataccgtaacaatg tttgtcattttgaaatacttaatgccaagtaacaatgcatgctttggaaatttggaagat ggttttattctttgagaagcaaatatgtttgcattaaatgctttgattgttcatatcaag aaattgattgaacgttctcaaaccctgtttacggtacttggtaagagggagccggtttgg gagagaccattgcatcgctgtccaagtgtttcttgttaagtgcttttaaactggagaggc taacctcaaaatattttttttaactgcattctataataaatgggcacagtatgctcctta >32215_i_at HG-U95Av2 aacagattactgtctattgtcagcatcattttcatctgtaagtcactactggaatatatt

>32216_r_at HG-U95Av2 aaatggactgggatagaggacagactgatagtttctttctttcatatcacatgtatagag aaataattatatcagaanctcacaaacctagacatggaaaaacagattactgtctattgt cagcatcattt ca ctgtaagtcactactggaata atttttcttttaatttccagtga ctttagaatacacacagttttt

>32285_g_at HG-U95Av2 ctatgtggacccacgcaaagatagcgagaaatatgccgaggagaacttcaaaacctttgt gttcgaggagacacgattcaccgcggtcactgcctaccagaaccatcggatcacgcagct caagattgccagcaatcccttcgcgaaaggcttccgggactgtgaccctga

>32319_at HG-U95Av2 gtctatgttcttgttgctatgagtcaaggagtgtaaccttctcctttactatgttgaatg tatttttttctggacaagcttacatcttcctcagccatctttgtgagtccttcaagagca gttatcaattgttagttagatattttctatttagagaatgcttaagggattccaatcccg atccaaatcataatttgttcttaag atac gggcaggtcccctattttaagtcataatt ttgtatttagtgctttcctggctctcagagagtattaat

>32321_at HG-U95Av2 ccacagagagcctccactagagtgatgctaagtggaaatgtgaggtgcagctgccacaga gggcccccaccagggaaatgtctagtgtctagtggatccaggccacaggagagagtgnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntccc acagataccttttctctcccatgaccctttaacagcatctgcttcattcccctcaccttc ccaggctgatctgaggtaa

>323_at HG-U95Av2 TIGRSequence

>32464_at HG-U95Av2 gagggtcttgtatctcctcttctcgttcctcttcatattcctgatgcctcttccaggtgt ttttggtggtataggcgatcctgttacctgccttaagagtggagccatatgtcatccagt cttttgccctagaaggta aaacaaattggcacctgtggtctccctnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntgcggattcagaaagggctcc ctcatcagagacgtgcgacatgtaaaccaa

>32531_at HG-U95Av2 tagtac gtaaacaggctttagtcattaatgtgagagacttagaaaaaatgcttagagtg gactattaaatgtgcctaaatgaattttgcagtaactggtattcttgggttttcctactt aatacacagtaattcagaacttgtattctattatgagtttagcagtcttttggagtgacc agcaactttgatgtttgcactaagattttatttggaatgcaagagaggttgaaagaggat tcagtagtacacatacaactaatttatttgaactatatgttgaagacatctaccagtttc tccaaatgccttttttaaaactcatcacagaagattggtgaaaatgctgagtatgacact tttcttcttgcatgcatgtcagctacataaacagttttgtacaatgaaaattactaattt gtttgacattccatgttaaactacg

>32551_at HG-U95Av2 attttcatatccagcctaaaggtggttgtttattatatagtaataaatcattgctgtaca atannnnnnnnnnnnnannnnannnnnnnttttgtcaganantttagattgtgaa attt tgtaaaaaacagtaagcaaaattttccagaattcccaaaatgaaccagatatcccctaga aaattatactattgagaaatctatggggaggatatgagaaaataaattccttctaaacca cattggaactgacctgaagaagcaaactcggaaaatataataacatccctgaattcagga cttccacaagatgcagaacaaaatggataaaaggtatttcactggagaagttttaatttc taagtaaaatttaaatcctaacacttcactaatttataactaaaatttctcatcttcgta cttgatgctcacagaggaagaaaatgatgatggtttttattcctggcatccagagtgaca

>32588_s_at HG-U95Av2 catctccgacgactgaggcaagagggcgccagtgaggaggaagggaaggcggttcagaga tgttggaggacacccctcgccatctcgcccttgctgggggcacgggagtggggggggtga catgggccctaggcagactgcaagcccgaccgagcacttggactcgaactctgtgcc

>32606_at HG-U95Av2 acagaactacaggtgcacccaaccacggacatgcattaactcgtcatgagaaatctaggt aggctaagtaggatgagagaatgtttgtcactcccaaaaa a ctggagaggaagaatgg aggattggcattgagatccatgtggacaagctaagtgggctctgtctgaaagctggcatt catccacaacattaaaaaaata caaaataagaaaggctgtaaattaaaaagaaaacaca gaaaatac gctctcataaagatctgattgccttgnnacaggccctgtgngannnnntca aacgcatcactcccaactcccattgcagaagaaaagctattcaactctcagcggtggagg agtgcatnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncagacgcggatctt ggaaatccaggacttcttggnnaagttgactgaaggtatattagatatttccccacaaaa a actatttggattctcccaccccctccctcccttga gggacaacatcctgta

>32609_at HG-U95Av2 gcccgcgtctcgaaggggcacctgtgaactcaaaaggctcttttc

>32610_at HG-U95Av2 acctgggctccgaggtgtacaggatgctgcggganccagccgagcccgtggccgcggagc ccaagcagtcaggctccttccgctacttgnagggca gctanaggccggcgagggcgggg attggcccgnncctggcggcccccggaacctcaagcccacggccagcaagctgggcgctc cgctgancggcctgcaggggctgcccgagtgcacgcgctgcggccacggcatcgtgggca ccatcgtcaaggcacgggacaagctctaccatcccgagtgcttcatgtgcagtgactgcg gcctgaacctcaagcagcgtggttacttctttctggacgagcggctctactgtgagagcc acgccaaggcgcgcgtgaanccncccgagggctacgacgtggtggcggtgtaccccaatg ccaaggtggaactcgtntgagctgggaccc gctcccacgcctgcttcttaaggtccctg ctcggccggtgtaaatatgtttcac

>32616_at HG-U95Av2 aataccagcagcagccttagagcacagggagacccgtccatttggcaggggtggctgcct catttagagaggaaaagtaaccatcactggttgcacttatgatttcatgtgcggggatca tctgccgtgcctggatcctgaaatagaggctaaattactcaggaagaacaccctctaaat gggaaagtattctg actcttagatggattctccactcagttgcaacttggacttgtcct cagcagctggtaatcttgctctgcttgacaacatctgagtgcagccgtttgagaagaaaa catctattctctccaaaaatgcacccaactagctctatgtttacaaatgg

>32640_at HG-U95Av2 gtgatttttctatcggcacaaaagcacta atggactggtaatggttacaggttcagaga ttacccagtgaggccttattcctcccttccccccaaaactgacacctttgttagccacct ccccacccacatacatttctgccagtgttcacaatgacactcagcggtcatgtctggaca tgagtgcccagggaatatgcccaagctatgccttgtcctcttgtcctgtttgcatttcac tgggagcttgcactannnnnnnnnnnnnnnnnngcagtgatcagggtcctgcaagcagt

>32668_at HG-U95Av2 tcccctcttttgtgaagaaagcgggtccaaatgtgattcaaacaactgtacggagtggca tattagaattgccctaaactgaactgcaaataattatgtgtgtatgtatatgtgtgggaa agagaatg actgtatatgtgtatgttatacagacatatacacatacatacattgaccca caggacattgtaaaatattatcacatgacatcttaagtagaaataagtagggacttttat tccatcctttttttcacgtttacattttaattattacaagttgc cctgccccctccctg aactattttgtgctgtgtatatcactgctttatataagttattttttaaggtgaactcag atgttatggttttgtaaatgtctgcaatcatggataggaataaaatcgcttatttgagag ctttcattaaa

>32700_at HG-U95Av2 agtactaccaggtgccaaggaaggggatncaggccaaagaggtgctgaaaaaatatttgg agtcnnaggagnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncactctcagaaaagg aaaaagcgattgaagtggaacgtataaaggctgaatctgcagaagctgcaaagaaaatgt tggaggaaatacaaaagaagaatgaggagatgatggaacagaaagagaannnnnnnnnnn nnnnngtgaaacaattgactgagaagatggagagggacagggcccagttaatggcagagc aagagaagaccctcgctcttaaacttcaggaacaggaacgccttctcaaggagggattcg agaatgagagcaagagacttcaaaaagacatatgggatatccagatgagaagcaaatcan nnnnnnnnnnnnnnaacatactctaaaagtccaaggagcaaaatttgcctgtccagctcc ct

>32718_at HG-U95Av2 cagactgagcaagtggagtagcagaaccaggagcctcttcnnnncnnnaggaaagatnnn nnnnnnnnnnnnnnaagggaaattcctaggattggctgtcccctgccaagcttggtggag cgtctgcaccttggctgcgccgcctgtgcatttgccagtttcctcccactgagaggatgg aggtgtccgcacagctttgggcctcgtgagggatctgncctcctgagcaaagagctcttg atcccgatttcatgcacagccctgcagtaaggagcccagaaggaacatgtgtttcctgtt aaaactcctcttgttctcttttcttacattatgacgtttgttttcaaggagagggtttaa aaatgggatcctgtaagcagacttgggcagtctccttttgaaataggttgtctgtacatg ttctaatgttttgtagaacac

>32736_at HG-U95Av2 tcctgccttcctgagggccagaggggagccccaggacccattaagccacccccgtgttcc tgccgtcagtgccaacnnnnnnnnnnnnnnncatctacccgttcactccagtcccacccc acgcctgactcccctctggaaactgcaggccagatggt gctgccacaacttgtgtacct tcagggatggggctcttactccctcctgaggccagctnnncnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnaaatgagtgtctcagaagtgtgctcctctggc ctcagttctcctcttttggaacaacataaaacaaatttaattttctacgcctctggggat atctgctcagccaatggaaaatctgggttcaaccagcccctgccatttcttaagactttc tgctncactcacaggatcctgagctgcacttacctgtgagagtcttcaaacttttaaacc ttgccagtcaggactttt

>32737_at HG-U95Av2 acagacggacgtcttcctcatctgcttctccctcgtcagcccagcctcttatgagaacgt ccgcgccaagtggttcccagaagtgcggcaccactgccccagcacacccatca cctggt gggcaccaagctggacctgcgggacgacaaggacaccatcgagaaactgaaggagaagaa gctggctcccatcacctacccgcaggncnnnnggcactggccaaggagattgactcggtg aaatacctggagtgctcagcnctnacccnagagaggcctgaaaaccgtgttcgacgangc catccgggcngtgctgtgccctcagcccacgcggcannnnnnnnnnnnnnnnnnnnnnct cctctaggggttngcanccnnnnnnnncnnnntagatnggtntgntncnncnnnnnnnna ggnncncgnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnggagcccttcacgggacg ctacagcctgtgcc

>32772_s_at HG-U95Av2 ggagacactatattcaatcgtgctaagctcctcaatgttggctttcaagaagccttgaag gactatgactacacctgctttgtgtttagtgacgtggacctcatnccaatgaatgaccat aatgcgtacaggtgtttttcacagccacggcacatttccgttgcaatggataagtttgga ttcagcctaccttatgttcagtattttggaggtgtctctgctctaagtaaacaacagttt ctaacnnnnnnnnnnnnnnntaataattattggggctgnggaggngnagatgatgacatt nttaacagattagtttttagaggcatgtctatatctc

>32786_at HG-U95Av2 cgcttggacggctgggcacacgcctcccactggggtccagggagcaggcggtgggcaccc accctgggacctaggggcgccgcaaaccacactggactccggccctcctaccctgcgccc agtccttccacctcgacgtttacaagcccccccttccacttttttttgtatgtttttttt ctgctggaaacagactcgattcatattgaatataatatatttgtgtatttaacagggagg ggaagagggggcgantcnnnggcggagctggccccgccgcctggtactcaagcccgcggg gacattgggaaggggacccccgccccctgccctcccctctntgcaccgtactgtggaaaa gaaacacgcacttagtctctaaagagtttatt

>32794_g_at HG-ϋ95Av2 gactccaga actgcctgagcagccgcctgagggtctcggnnnnnnnnnnnnnnnnnncc cgcaaccacttccgctgtcaagtccagttctacgggctctcggagaatgacgagtggacc caggatagggccaaacccgtcacccagatcgtcagcgccgaggcctggggtagagcagac tgtggcttnacctcngngtcntaccagcaaggggtcctgtctgccaccatcctctatgag at

>32818_at HG-U95Av2 tagaaccagccgtattttacatgaagctgtataattaattgtcattatttttgttagcaa agattaaatgtgtcattggaagccatccctttttttacatttcatacaacagaaaccaga aaagcaatactgtttccattttaaggata gattaatattattaatataataatgatgat gatgatgatgaaaactaaggatttttcaagagatctttctttccaaaacatttctggaca gtacctgattg

>32847_at HG-U95Av2 tccaaggaccggatgaagaagtacatggcaagaaggaantggcagaaaacgggcaatgct gtgagagccattngnagactgtcctctnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnagggtcanccaaccagcccgctcaatgcagaaaaactagaatctnnngaag atgtgtcccaagctttccttgaggctgt gctgaggaaaagcctcatgtaaaaccctatt tctctaagaccattcgcgatttagaagttgtggagggaagtgctgc agatttgactgca agattgaannnnnnnnnnnnnnnnaggttgtctggttcaaagatgaccagtcaatcaggg agtcccgccacttccagatagactacgatgaggnnnnnnnnnnnnnnnnaattattagtg atgtttgcggggatgacgatgccaagtacacctgcaaggctgtcaacagtcttggagaag ccacctgca

>32944_at HG-U95Av2 accagaccagccaagaaactgaaacnnnnnnnnnnnnnnnnnnnnngagaaacctacaca gatgatcttccaccacctcctgtgccgccacctgctataaagtcacctactgcccaatcc aagacacagctggaagtacgnnnnnnnnnnnnnnnaaaactcccttcta ggatgcaaga acagacagannnnnnnnnnnnnnnngaagcagttacaaggggagagaagtgttggatgga agacaggttgttgacatgcgaacaaatccaggtgatcccagagaagcacaggaacagcaa aatgacgggaaaggacgtggaaacaaggcagcaaaacgagaccttccaccagcaaagact catctcatccaagaggatattctaccttattgtagacctacttttccaacatcaaataat cccagagatcccagttcctcaagctcaatgtcatcaagaggatcaggaagcagacaaaga gaacaagcaaatgtaggtcgaagaaatattgcagaaatgcaggtacttggaggatatgaa agaggagaagataataatgaagaattagaggaaactgaaagctgaagacaaccaagaggc tt

>33102_at HG-ϋ95Av2 atatttttggagtcccattgtttcagtgggcattaacagaatgctttaaaaacttctaag acaagaatctatagcattagta acactggcacataattttttaaaaagttttaagaaaa gattcatttggaattttattcacagtataaaatttcctcacctgaagtaactttgtttgc caa

>33103_s_at HG-U95Av2 tctcacagaaggagaacttgaagagtataagaggacaatcgaacgtaaacaacaaggcct agaagaaaaccatgagctgttttccaagagcttcatctccatggaagtgcctgtcatggt agtaaatggcaaggatgatatgcatgatgttgaagatgagcttgctaagcgagtgagtag gttaagcacaagtacaaccatagaaaacatcgagattactattaagtctccagagaaaat cgaagaagtcctgtcacctgaaggctccccttcaaaatcgccatccaagaaaaagaagaa attccgcactccttcttttctgaaaaagaacaaaaaaaaggagaaagttgaggcctaaat aaagtctttttataat at attataacaatgtgacattgcacatctaaataccacattt aagttgatca taatatgcaatggtagatcagattgggggatgtagcaaactggactt a agaac

>33113_at HG-U95Av2 tttctccagtgctcaactgttagatattaatcttggcaaactgcttaatcttgtggattt nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnagtgaaaggaaaaattgca ttagttggttgcatgaacttcngangggcagatattactgcacaaactgccatctcgctt catttttttaactatgncatttgagtancaganctaatttttaaaatatgctaaactgga anngattannnnnannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnntggctgtcccccccgccgccccccccacccccatatgtacagatgataat agggtgtggaatgtcgtcagtggcaaacatttcacagannnttattttgtttctgtcttc aacatttttgacactgtgctaatagttatattc

>33130 at HG-U95Av2 cttgtaagccacttgtttggttatgatttgtgtcttatcagggaaaaggtgcccagctgc cagcccagctccgctgcntatctttgcctcacttagtcatgtgcaattcgcgttgcagag tggcagaccattagttgctgagnnnnnnnnnnnnnnnnntgtgctcagaagagcacctgc ccaaagtttttctggttttaatttaaaggacaaggctacat tattcagctttttgagat gaccaaagctagttagggtctccttgatgtagctaagctgcttcagtgatcttcacattt gcactccagttttttnnnnnnnnnnnnnnnnnnttctacctctctatgtgcctgagtgat gatacaatcgctgtttagttactagatgaacaaatccacagaatgggtaaagagtagaat ctgaactatatcttgacaaat t attcaaacttgaatgtaaatata acagtatgtata ttttttaaaaagatttgcttgcaatgaccttata

>33235_at HG-U95Av2 gtgtcacaaagtcaataggtccttannnnnnnnnnnnnnnctaagggaaatccgaactga atttatgcacatagaattgtcaccctgactttgaagcctcaaacatggatcaaatctgtt gtgaaacatcaatatatgtagctggatgagtgactagtttcccttgtataatatgtgatc taagaaaattgctaatctttccctgccattttgagaaacacagtccaaacatgagcataa acagaatttcctgcaatacatncccagtaggtnccacctagtttacaacttaaactagtt tgtgaaacatttgtctgtatacattttatattttgtacattttgatgtaacatatcatgt aaataggcagaaacagtgaaataaatcatctgaaaagttttgtagtctttgtaaagcccc aacaataagtacttggtgtcaatggacttaactggatgatgtattttctattggtttatt gttcctctagcttgtaaaccagcttgcatatatttttttgcaaatgtgcaccctg atct gtctaaatt

>33236_at HG-U95Av2 tgagcaacagtgcagaggtgaaacgggagcnnnnnnnnnnnnnnnngggaggctgttgct atcgggtcaacaacagcttggaccatgagtaccaaccacggcccgtggagg gatcatca gttctgcgaaggagatggtnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntggaaa aggccaaggttgaagtcggtgtggccacggcgcttggaatcctggttgttgctggatgct cttttgcgattaggagataccaaaaaaaagcgacagcctgaagcagccacaaaatcctgt gttagaagcagctgtgggggtcccagtggagatgagcctcccccatgcctccagcagcct gaccctcgtgccctgtctcaggcgttctctagatcctttcctctgtttccctctctcgct ggcaaaagta gatctaattgaaacaagactgaaggatcaataaacagccatctgcccc

>33243_at HG-U95Av2 tgcttctggaattgagttctccttttaagtaccaatgatacttaaatttctcagaaatgt aatggtgtgtcattgccttgaaatgcttgct agggcttcttttatgt atcttaaaaag tgnnnnnnnnnnnnnnnttttttacatccatttcacatgtaagagacaaaaaagtctaga ttggtcttgatattgagataataaaaagtaagtagcattaagaaaggtaacaatncttca ttcnnnnnnnnnnnnnnnnntgaaacaatttaggggaatgaggggcaaaaggggagaaat actgctaaagaacatgagcataaaaatgcgtgcgtttcagtgtttaagaaggcttgataa agaatgtcacttttttatttaactgataagatttttgttattttttactttgataagtaa accaaagaatatttgtatttcaancagtttgtgtggtgtttctatataattttctgtgta taaataannnnnnnnnnnnnnnnnnnnnnnntaaaaaagnnnnnnnnnnnnnnnnnccag ctatgtcctctaggaaatgacag

>33249_at HG-U95Av2 cacagcatgcagactgggagttgctagcaaacaaatggcttacntacnnaangcagcttt tagttcagacttagttttta aaaatgggaattnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnncagctttttgtattaacaaagttactggctctttgtgtgtctcca ggtaactnnnnnnnnnnnnnnnncaaagccatattctaaattcactgttgaatgcctgtc ccagtccaaattgtctgtctgctcttatttttgtaccatattgctcttaaaaatcttggt ttggtacagttcataattcaccaaaagttcatataatttaaanaaacactaaattagttt aaaatgaagcaatttatatctttatgcaaaaacatatgtctgtctttgcaaaggactgta agcagatt

>33281_at HG-U95Av2 acccacaggaaagagtgtggcagcaactgcntggctgacctttctatcttctctaggctc aggtactgctcctccatgcccatggntgggncgtggggagaagaagctntcnnacgcctt cccactccctctggtttataggacttcactccctagccaacaggagaggaggcctcctng gggtttccccagggcagtaggtcaaacgacctcatcacagtcttccttcctcttcaagcg tnncatgttnaacacagntntnnccnntcccntgtgatttnnganggnnnncnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnctatgcttggtctgactgagcctaaagt tgagaaaatgggtngccaaggccagtgccagtgtcttggggcccctttggctctccctca ctctctgaggctccagctggtcctgggacat

>33295_at HG-U95Av2 cagactgggtgcaggccaggtcccaggcctcaccctggggctcactgtgggaatttgggg agtggctgccctactgacactgcctgtcaccctggccagtggtgcttntggtggactctg caccctgatatacagcacggagctgaaggctttgcagnccacacacactgtagcctgtct tgccatctttgtcttgttgccattgggtttgtttggagccaaggggctnaagaaggcatt gggtatngggccaggcccctggatgaatatcctgtgggcctggtttattttctggtggcc tcatggggtggttctaggactggatttcctggtgaggtccaagctgttnnnnnnnnnnnn nnntctggcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntctgccaccaggccacccgcaccct cttgccctctctgcccctccctgaaggatggtcttctcatctggacacccttggaagcaa atcctagttctcttcccacctgtcaacctgaattaaagtctacactgcctttg

>33304_at HG-U95Av2 gttcatccggcctgagggagagatcaccgattacagaaccngggtcagcggggtcacccc tcagcacatggtgggggccacaccntttngccgtgnccaggctagagatcctgcagctcc tgaaaggcaagctggtggtggg catgacctgaagcacgacttnnnnnnnnnnnnnnnnn acatgagcggctacacaatctacgacacgtccactnnnnnnnnnnnnnnnngtgaggcca agctggaccactgcaggcgtgtctccctgcgggtgctgagtgagcgcctcctgcacaaga gcatccagaacagcctgcttggacacagcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nctatcaaatctcccagagaatccgagcccgccgagggctgccccgcctggctgtgtcag actgaagccccatccagcccgttccgcagggactagaggctttcggctttttgggacagc aactaccttgcttttgga

>33331_at HG-U95Av2 gaaggacccatgtcccaggaaccgcgntgcgccacctgcactcacccccctcacattctc ttaagcacccggtngccctccgaggcctggcggaatggtggtgcccacggggttgggcaa gggctcaccaggacctcaacgggcaaagttgtgcacactaaaata caaatcaaggtgct tggttttaaagtaaatgtttttctaaagaaagctgtgntcttctgttgacccagacgaat anngcacagccctgtaactgcacgtgccttctgtcattgggaatgaaataaattattacg agaaaggganttgtcctaannngtttgaggccttacagttttgtatctacatttttcccc tcctggggtttgcggggacagggacagaactacaggagtcatgggaaagaaaattctggc ttcactactgctcactgctcactttctgatcactctganacnnntttttttttttttttt ttgcaacctgataccttgaaaag

>33371_s_at HG-U95Av2 cgacctctcagatattagggaggttcccctgaaggatgc aaggaatacgctgaatccat aggtgccatcgtggttgagacaagtgcaaaaaatgctattaatatcgaagagctctttca aggaatcagccgccagatcccacccttggacccccatgaaaatggaaacaatggaacaat caaagttgagaagccaaccatgcaanccagccgccggtgctgttgacccaagggcngtgg tccacgntacttgaagaagccagagcccacatcctgtgcactgctgaaggaccctacgct cggtggcctggcacctcactttgagaagagtgagcacactggctttgcatcctggaagnc ctgcaggggnnngggcaggaaatgtacctgaaaaggattttagaaaaccctggnaaaccc accacaccaccnnnacaaaatggcctttagtgtatgaaatgcac

>33410_at HG-U95Av2 agtgactgtgtttccctcaaagactgtagctcagtattcgggagtaccttggtggatcat cctagtggc

>33411_g_at HG-U95Av2 ctgtagcgtgaacgtgaactgtgtgaacatcagatgcccgctgcgggggctggacagcaa ggcgtctcttattttgcgctcgaggttatggaacagcacatttctagaggaatattccaa actgaactacttg

>33439_at HG-U95Av2 gaccaggtgccttgccgcagagaaaancnaccaaagtctcctgttcgctcataaagaagt ttttgggatgggagagannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntt tttacagaggnnnnnnnnnnnnnnnnncaacacaaaacnncttcccctttttaaaatgat ttctgttctaatgccatagatcaaaggcctcagaaaccattgtgtgtttcctctttgaag caatgacaagcactttactttcacggtggtttttgttttttcttattgctgtggaacctc ttttggaggacgttaaaggcgtgttttacttgtttttttaagagtgtgtgatgtgtgttt tgtagatttcttgacagtnnnnnnnnnnnnnnnnnnnnnnnnnngcct t taaagacnc tacg gatctga tgagatgtaca

>33533_at HG-U95Av2 aatagtattccagcagacattgtttttatcattaaagacaaagatcatccaaaatttaaa agggatggatcaaa a aatttactgctaaaattagtttacgagaggagattgtgtggcg tgctcaattaatgtaccaacactggatggaagaacatacctatgtcagtaaatgatattg tgaancccggaatgaggagaagaattattggatatgggctgccatttccaaaaaatnnnn nnnnnnnnnnnnnnnnnnnnnnnnnntttgaggtgtccttcccagatactata cttctt catnnaaagaagtactnnnnnnnnnnnnnnnnnnnnnnnagaatgannnacttnnntana natattttgataaggcactgaaaatataaaaggantggtagtttactgatgtagatgtga attctgtataaagatgtgtaaattnttttgagggttcattaaattgcatgaatagagaca ggtcaaataaataggcaaaagggatttttacagttagagatagaagagaaaaccattcac tgtattt

>33707_at HG-U95Av2 cgtggccgggctct c acccgaagnatagtgcccgaagttgctgcttggcatagatgag cctcagcttccagggcactgtgggcntgttggtctactagggccctgangtccacctggc cttcctgttcttcactcccttcagccacacgcttcatggccttgagtnnnnnnnnnnnnn nnnnnnnnnnccaatcaccagtgaccagctagactgtgattttgatagcgtcattcagaa gaaggcgtccaaggagctgaaggtggtgaaatttgtcctgcaggtccctcgggagatcct ggagctggagcatgagtgtctgacaatcagaagcatcatgtccaatgtccagatggccag aatgaatgtgatagttcagaccaatgccttccactgctcctttatgactgcacttctagc cagtagctctgcacaagttagctctgtaga

>33731_at HG-U95Av2 ctgtgtatgtcagttgctgcagaaatggatttggaagatggaggagagatgcccaagcaa cgggatcccaantctaacnaaacaccatctggaatcc gatgtggaaagcaggggtttct ggtctactggctagagctaaggaagttgaaaaggaaagctcacttctttggaggcacctg tccagaagcctggcctaggcagcttcaacctttgaacttactttttgaaatgaaaagtaa tttatttgttt gctacatactgttccagacttttaaaggggacaatgaaggtgactgtg gggaggagcatgtcaggtttgggcttggttgttttagaagcacctgggtgtgcctaccta ctcctcttttcttttaaaagggcccacaatgctccaatttcctgtctcctttagagagac atgaaact

>33764_at HG-U95Av2 gtgtattaccagtatttacttgctttcttgatttcaccaaaaccaaatttaatttaaagg accacattaatttttcaaagggaaagagacaattaattgtacataatgtat cacacaca naaaaaaaaatacctgtagaaa attattccagcatagcnggaaaacaaacaaaagtatt ggactgtcggaggtgagcctgtgcgtctgtaaccctttgtgactcctgagcgtgcgctgt cttnctaggttaactcacgaagtacattctctgtcttactgatactgtaggttcacccat ttttttttaatttcctcgcaaataacaagaccnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnttcttttatatgcagcaaacacaccgtccatttctgaagaggcttcggcntgaag gcattttccaatgatgttagtgcacaaaacgctttaaattagactggaactgccagaatc aaatgtaaatgaggaatttctcgtacccctactgcatggtatcgattttta

>33772_at HG-U95Av2 ttgcttccaggtgtgcctggcatgggcctggcccaggaagacaccacctcactgaggact ttgcgaatatcagagacctcagactcttcacagggtcaggactcagagagtgtcttac g gt^'ggatgaggctggtgggagcggcagggctgggcctgcccntaaggggagctccctgcaa gtcacatttcccagtgaaacactgaacttatcagaaaaatgtatataataggcaaggaaa gaaatacagtactgtttctggacccttataaaatcctgtgcaatagacacatacatgtca catttagctgtgctcagaagggctatcatcatcctacaactcacattagagaacatcctg g

>33790_at HG-U95Av2 cccacagcatgaagatctccgtggctgccattcccttcttcctcctcatcaccatcgccc tagggaccaagactgaatcctcctcacggggaccttaccacccctcagagtgctgcttca cctacactacctacaagatcccgcnnnnnnnnnnnnnnnnnnntactatgagannnnnnn nnnnnnnnnnannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnagaactgagtgacc cagaaggggtggcgaaggcacagctcagagacataaagagaagatgccaaggccccctcc tccacccaccgctaactctcagccccagtcaccctcttggagcttccctgctttgaatta aagacc

>33791_at HG-U95Av2 agaatatctagcatgtaaggcctttcaatattaatataagcccaatatcagctctttctc tttgtatttcatctctttctactctcctatttgtattttgtgttcctatcaaagtgtcgt atctgggag

>33802_at HG-U95Av2 ttctttctagagagggaattctcttggctggnttccttaccnnnnnnnnnnnnnnnnntn nngggcctccagccctctcactgtgtccctctctctggaaaggaggaaggagcctatggc atcttccccaacgaaaagcacatccaggcaatggcctaaacttcagagggggcgaaggga tcagccctgcccttcagcatcctcagttcctgcagcagagcctggaagacaccctaatgt ggcagctgtctcaaacctccaaaagccctgagtttcaagtatccttgttgacacggccat gaccactttccccgtgggccatggcaatttttacacaaacctgaaaagatgttgtgtctt gtgtttttgtcttatttttgttggagccactctgttcctngctcagcctcaaatgcagta tttttgttgtgttctgttgttttta agcagggttggggtggtttttgagccatgcgtgg gtggggagggaggtgtttaacggcactgtggccttgg

>33803_at HG-U95Av2 tttctaccatttcagagaggccttttggaatgtggcccctgaacaagaattggaagctgc cctgcccatgggagctggttagaaatgcagaatcctaggctccaccccatccagttca g agaatctatatttaacaagatctgcagggggtgtgtctgctcagtaatttgaggacaacc attccnagactgcttccaattttctggaatacatgaaatatagatcagttataagtagca ggccaagtcaggcccttattttcaagaaactgaggaattttctttgtgtagctttgctct ttggtagaaaaggctaggtacacagctctagacactgccacacagggtctgcaaggtctt tggttcagctaagctaggaatgaaatcctgcttcagtgtatggaaataaatgt tcatag aaatgtaacttttgtaagacaaaggttttcctcttctattttgtaaactcaaaatatttg tacatagttatttatttattggagataatctagaacacaggcaaaatc

>33849_at HG-U95Av2 tcttactggaatgtctaggcactgtacagttattatatatcttggttgttgtattgtacc agtgaaatgccaaatttgaaaggcctgtactgcaattttatatgtcagagattgcctgtg gctctaatatgcacctcaagattttaaggagataatgtttttagagagaatttctgcttc cactatagaatatatacataaatgtaaaatacttacaaaagtggaagtagtgtattttaa agtaattacacttctgaattt t tttca attctatagttggtatgacttaaatgaatt actggagtgggtagtgagtgtacttaaatgtttcaattctgttatattttttattaagtt tttaaaaaattaaattggatattaaattgtannnanannannnantaattttaaactgaa tgccctcaataagtaatactgaagnnnnttcttaaatgaagataaattatctccaatgaa aagcatgacatgtgtttcaatagaagaatcttaagttggctaaattcaaagtgcttgaca tcaaaatgttctngagtgattagctactagattctgaatcatacatcacatctgactaga gaccag

>33862_at HG-U95Av2 tcacttggcgaggagcccgcctgctccggcccctcctgcagttcaccttgatcatgatgg ccttctacacgggactgtctcgcgtatcagaccacaagcaccatcccagtgatgttctgg caggatttgctcaaggagccctggtggcctgctgcatagttttcttcgtgtctgacctct tcaagactaagacgacgctctccctgcctgcccctgcta ccggaaggaaatcctttcac ctgtggacattattgacaggaacaatcaccacaacatgatgtaggtgccacccacctcct gagctgtttttgtaaaatgactgctgacagcaagttcttgctgctctccaatctcatcag acagtagaatgtagggaaaaacttttgcccgactgatttttaaaaannaaaaaaaaaatg ttttactatgtggccttcca

>33900_at HG-U95Av2 tgtgacatccggagtcctggagccgggtgtnccagtggnancactaggtnnntgctgnct ncnnnnnnngnnnnnnncncannnnnnnntnnttngtcccccacaacctgccccggnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnttctcccacgacggctcaccctcccctccat ctgcgttgatgctcagaatcgcctacctgtgcctgcgtgtaaaccacagcctcagaccag ctatggggagaggacaacnnnnnnnnnnnnnnnnnnnnncggtctggggtgaggagtgtg gggagcttgggcatcctcctccagcctcctccagcccnnnnnnnnnnnnnnncctgtggt gcccagaaaagtgcccctaggttggtgggtctacaggagcctcagccaggcagcccaccc caccctggggccctgcctcaccaaggaaataaagactc

>33925_at HG-U95Av2 ttggtttcggacgacccttgctctgaccggaagagaagtccctatcccacacctgcctgt cacgttccctcccctttccccagcgcactgttgagggcagcctctccagctctcttgttt atgcaaacgccgagcgcctgggaggctcggtaggaggagtcttccacggccccgccccgn ccctgtcggtcccgccctnccccccgccgggctcctggggctgtggccgaaaggtttctg atctccgtgtgtgcatgtgactgtgctgggttggaatgtgaacaataaagaggaatgtcc aagtgnnnaaaaaaaaaaaaannagggagtttgggtgcacaaggcctccgc

>33943_at HG-U95Av2 gtgaccacgtgaccaacttgcgcaagatgggannnnnnnnnnnnnnnnnnnnnnnnnnnn nnnttgacaagcacaccctgggagacagtgataatgaaagctaagcctcgggctaatttc ccnatagccgtggggtgacttccntggtcaccaaggcagtgcatgcatgttggggtttcc tttaccttttctataagttgtaccaaaacatccacttaagttctttgatttgtaccattc ttcaaataaagaaatttggtacccaggtgttgtctttgaggtcttggatgaatcagaaat ctatccaggctatcttccagattccttaag

>34022_at HG-U95Av2 gtatcattgacacttcctgcagggtggtccctngccctnacnaganctgaaantgaaaan gagancagcagctttctagggacagctggaaanggacttaatgtgtttgactatttctta cgagggttctacttatttatgtatttatttttgaaagcttgtattttaatattttacatg ctgttatttaaagatgtgagtgtgtttcatcaaacatagctcagtcctgattatttaatt ggaa a gatgggttttaaatgtgtcattaaactaatatttagtgggagaccataatgtg tcagccaccttgataaatgacagggtggggaactggagggtggggggattgaaatgcaag caattagtggatcactgttagggtaagggaatgtatgtacacatctattttttatacttt ttttttaaaaaaagaatgtcagttgttatttattcaaattatctcacattatgtgttcaa catttttatgctgaagtttcccttagacattttatgtcttgcttgtagggcataatgcct tgtttaatgtccattctgcagcgtttctc

>34075_at HG-U95Av2 aggacaacgactaccaccgcagcgacgagcaggtgagcannnnnnnnnnnnnnnnnnnnn nnnnnnnnnncgggctgaagcggaagtggatccgctgctcagcccaggcgaccgtcttgc atctgaagaagttcatcgccaaaaaactcaacctt catcctttaacgagctggacattt tatgcaacgaggagatcctgggcaaggaccacacactcaagttcgtggttgtcactaggt ggagattcaagaaggcgccgctcctgctgcactacagacccaagatggacttgctgtgaa tggtgccacacagcgcccacagactgggcnntcgcacccttggntnntcccggccgncgc gcttaagaacattgcctctgggtgtcatgtggaccagacttctgaataga

>34082_at HG~U95Av2 actctgtgcccgaatggtggtgcaggcgccctgtcctggttgtgttgttacgtgtttgac cagcacaggggtccggtggggaaaatgtatgggttnntntcagttgttgctantnctgan nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnrmnnnnnnnnnnnnnnnnnnnnnnnat gattgtgtttaggtttgaaattgctcaagtgtctggctcaggtggtggttctgagacnnn nnnnnnnnnnnngagcccagatgcttaggtccactagggcccatctagggaagggaaagg agatttcagcggnttccccgaaaggaacaggactgtcgggatgcttcccggatgtctaca gttgccccttcctgcagtgagattactgcttcctgtttccctccagctcttcccagcagc agtgagggagtattaagagggatcttgtagtcgctgcctggctcttgtgggcggcccttt aagactcaggttgagctcagccaagtcccgcttgcgccaggntttgattcaaggtngtca gnaagttagattgtcaaaacatttcgagagagaggcag

>34209_at HG-U95Av2 agatccggcctcaggacttacacctcctgcctgacccccaggcttctctctcctttctcc cagcaaactgcagtggcagaaaggaggttcagaggctgggaaagtgggcctccccttgca actcagagctgctgcactcaggagggccccatccaatcccgggcccctgcagggaaaagc gctgggtgtgtgtcanaggcgcagggtgggtggggctgccagccaggaccctggcctgca gcc gatccaaaccaaagactgtagaaccctggggtgtggctaacggcccctccagcacc catagccaggtcttcctggcccttgaggctgggctggcggacaggcacctacc

>34232_at HG-U95Av2 atatggcaacggaacatcctcaagcagaggtagtaaaacaggnnnnnnnnnnnnnnnaaa gtaaagtgttgggtgaagtggggaaacaggacagcagctctgctagcttggctagnnnnn nnnnnnnnnncgggaagaaggaggtggctgagaagagccagatcaacctcattgataaga aatggaagcccctgcaaggtgtggggaacctggcagnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaatgaaaccacaaggcttgagaatag aaattaaaagcaaaaataaagttcggcctgggtctctctttgatgaagtaagaaagacag cacgcttaaaccgtagaccaagaaatcaggagagttcaagtgatgagcagacgcctagtc gggatgatgatagccagtccaggagtccaagtagatctcgaagtaaatctgaaaccaaat caagacacagaacaaggtctgtctcctatagtcactcaagaagtcgatc

>34261_at HG-U95Av2 ctctaactggcctggctctggaagggctggtgaggactctgcctccttgcctgcctacaa ggtgcctggtttgcagcaggctctccgctctttccagcaaagctgctcagagagggtgtc cagcacagtggagaggccggaagtgagacgggcagacggcacctgcagcctgaaacgcac cgctcctgcgtgcgcccccacctggtccccggatgcccccaccacctggacagaggccac actgactgcccacccagctgtggcgggaggtgcagagcagagggctttagggagcagtga ctgcggtcacccctttagttctctgggtgtagaccacaccacctcccactgggcaccccc caacacggtgtcctgccacccagcgcctggctccaggaaaacacgcttgccttccttccc ggcannntcgccactctccttatggactctgttctgtttgtacatggctgacggaaatct ctttggt

>34265_at HG-U95Av2 gatgctagacgaaaacccacattacctgttaggcctcagcatggcttatgtgcacgtgta aatggagtccctgtgaatgacagcatgtttcttacatagataattatggatacaaagcag ctgtatgtagatagtgtattgtcttcacaccgatgattctgctttttgctaaattagaat aagagcttttttgtttcttgggtttttaaaatgtgaatctgcaatgatcataaaaattaa aatgtgaatgtcaacaataaaaagcaagactatgaaaggctcagatttcttgcagtttaa aatggtgtctgaggttgtactattttggccaagtctgtagaaagctgtcatnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnntgggcattgttatacaccagtaaagaaggctgtac tcaagaggaggagctgacacatttcacttggctgcgtcttaataaacatgaatgc

>34272_at HG-U95Av2 tgaattcatctcagtccaggcaaccaaagaggtgaacctggattcnnnnnnnnnnnnnnn nncaagccggaacatgctagagcctacaataacctgctttgatgaggcccagaagaagat tttcaacctgatggagaaggattcctaccgccgcttcctcaagtctcgattctatcttga tttggtcaacccgtccagctgtggggcagaaaagcagaaaggagccaagagttcagcaga ctgtgcttccctggtccctcagtgtgcctaattctcacctgaaggcagagggatgaaatg ccaagactctatgctctggaaaacctgaggnnnnnnnnnnnnnnnnatnnnnnnnnnnnn nnnnnnnnnnattgtagnctaatat catgctgcctgccatgt

>34273__at HG-U95Av2 tgatttgaccactgacagcctccaccttgagcactattctaaggagcaaataccttagct cccttgagctggttttctctgatggcacttttgagctcctaagctgccagccttcccttc ttttcctgggtgctcagggcatgcttattagcagctgggttggtatggagttggcagaca ggatgttcaacttaatgaagaaatacagctaaggccttgccagcaacacctgccgtaagt tac ggctgagtgagggcatagaagttaaaggttactgtttttatcctctatcctttttt cctttcctgatcaaggtgctcttctcattttttcctgagaaccttagccatcagatgagg ctccttagtttattgtggttggttgttttttctttataatggctctgggctatatgccca tatttataaaccagcagcaggggaaagattatattttataagagggaacaaattttcaca atttgaaaagcccacataagttttctcttttnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnctttttaggctctgagactaaatga

>34288_at HG-U95Av2 tttgcaacaggcagagctgtgtcgcacagcagtgctgtncnnnanagccagctgaggaca ggcttgcctggacttctgtaagataggattttctgtgtttcctgaattttttatatggtg atttgtatttaaattttaagactttattttctcactattggtgtaccttataaatgtatt tgaaagttaaatatattttaaatattgtttgggaggcatagtgctgacatatattcagag tgttgtagttttaaggttagcgtgacttcagttttgactaaggatgacactaattgttag ctgttttgaaattatatatatataaatatatataaatatataaatatatgccagtcttgg ctgaaatgttttatttaccatagttttatatctnnnnnnnnnnnnnnnnnnnnnnnnnat atggaacnnnnnnnnnnnnnnnntgcagtttgtgacattaatagtattgtaaagttacat tttaaaataaacnnnnnnnnnnnnnnnnnnnnaaatctgcacacacaacgaacagttgca tttcagagagttctctcaatttgtaagt

>34304_s_at HG-U95Av2 agtacttgctaaaaatggcaacagaggagtgaggagtgctgctgtagatgacaacctcca ttctattttagaataaattcccaacttctcttgctttctatgctgtttgtagtgaaataa tagaatgagcacccattcnnnnnnnnnnnnnnnnnnnnnnnnnnnncatgtttgaaatga ggtctgtttaaagtggcaatctcagatgcagtttggagagtcagatctttctccttgaat atctttcgataaacaacaaggtggtgtgatcttaatatatttgaaaaaaacttcattctc gtgagtcatttaaatgtgtacaatgtacacactggtacttagagtttctgttt

>34375_at HG-U95Av2 ccagatgcaatcaatgccccagtcacctgctgntataacttcaccaataggaagatctca gtgcagaggctcgcgagctatagaagaatcaccagcagcaagtgtcccaaagaagctgtg atcttcaagaccattgtggccaaggagatctgtgctgaccccaagcagaagtgggttcag gattccatnggaccacctnggacaagcaaacccaaactccgaagacttgaacactcactc cacaacccaagaatctgcagctaacttattttcccctagctttccccagacaccctgttt tattttatta atgaattttgtttgttga gtgaaacattatgccttaagtaatgttaa ttcttatttaagttattgatgttttaagtttatctttcatggtactagtgttttttagat acagagacttggggaaattgcttttcctcttgaaccacagttctacccctgggatgtttt gagggtctttgcaagaatcattaataca

>34390_at HG-U95Av2 gtacagctgtgttctggtacaacctcttgcggancgggnnaagntgactaccgaacaaga catgctgcctgccctgtgcttgtgggctgcaagtgggtctccaataagtggttccatgaa cgaggacaggagttcttgagaccttgtggatcaacagaagttgactgacatccttttctg tccttccccttcctggtccttcagcccatgtcaacgtgacagacacctttgtatgttcct ttgtatgttcctatcaggctgatttttggagaaatgaatgtttgtctggagcagagggag accat ctagggcgactcctgtgtgactgaagtcccagcccttccattcagcctgtgcca tccctggccccaaggctaggatcaaagtggctgcagcagagttagctgtctagcgcctag caaggtgcctttgtacctcaggtgttttaggtgtgagatgtttnnnnnnnnnnnnnnnct gataccttgtttacatgtttgtttttatggcatttctatctattgtggct

>34432_at HG-U95Av2 caggtggctcccagctgcattctgagaactctgtgattgggcaaggccctcccctgcccc accagcccccacccgcctggagacacaccctcccccacaatctttctagacaggtgcttc aggacagaggacaggcatggcttccccttgggcctcctcagtaggcggtctggcctgacc cccaacaaagaagcctggaggtcagagaagcaaatgcngagcctgctccctcctaagaag atcccaagaatccaatggctcagtccttggtgatctaagacagcaaagaagtgtgcaagg agggccctgttagctcccactgtcctggtttctcctcctggagtctaatttccttggccc tctgagccttttgagtctgggccctggtccaatgctgctgttgt

>34636_at HG-U95Av2 tagaggggcaccttttca ggtctctgcacccagtgaacacattttactctagaggcatc acctgggaccttactc

>34666_at HG-U95Av2 tgctctattgtagcatttcttgatgttgcttagtcacttatttcataaacaacttaatgt tctgaataatttcttactaaacattttgttattgggcaagtgattgaaaatagtaaatgc tttgtgtgnattgannctgnanttggncnattttcttcagagagctaaattacaattgtc atttataaaaccatcaaaaatattccatccatatactttggggacttgtagggatgcctt tctagtcctattctattgcagttatagaaaatctagtcttttgccccagttacttaaaaa taaaatattaacactttcccaagggaaacactcggctttctatagaaaattgcacttttt gtcgagtaatcctctgcagtgatacttctggtagatgtcacccagtggtttttgttaggt caaatgttcctgtatagtttttgc

>34678 at HG-U95Av2 ccgaactatttgtcaatgaagattgtaaagccaaatgtgtaacaaaggcaaaggcttcat ttcaagagtcatccagcaatgagagaatcctgcctctgtagaccaacatccagtgtgatt ttgtgtctgagaccacaccccagtagcaggttacgccntgnnnncnnnnnncnnnnntnn nnnnnngnnnntnnnnnncnnnnnnnnnnnnnnnaacnnnnnnnnnnnnnnnnntgttat ctcttaagtattaaaagttttattttctaaagtttaaatcatgtttttcaaaatattttt caaggtggctggttccatttaaaaatcatctttttatatgtgtcttcggttctagacttc agcttttggaaattgctaaatagaattcaaaaatctctgcatcctgaggtgatatacttc atatttgtaatnnnnnnnnnnnnnnnnnnnnnnnaannnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnngcccacaaccattgctat ttttgtatgga

>34690_at HG-U95Av2 ttaaaaagccacattggagctcccttctacccactaaaaaataaccaatttttacatttt ttgagggggagtgagttttaggaaaggggaattaagattccagggagagctctggggatn nnnnnnnnnnnnnnnnnnntctctccccaagcccctttttagtgactaagtcaaggcccc aactcccctcccccaccctacgctgagcttattcgagttca tcgtactaataatccctc ctgcggcttcctcattgttgctgttttaggccaccccagctcagccaatgattcctttcc ctctgaatgtcagttttgtttttaaaagtcacttgcttannnnannnnagcgtatgtgta tttggnggggaaaancctaatttcnggggatttctgtggtaggtaatanggagaagaaan gggcactngggggctgttctccttccttccctggg

>34720_at HG-U95Av2 tctcaccaacgaaggctaggaggcggcgtcagagntgnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnncactctgatttctaaaagttaaaaaaaatatatgaaatctctgtnnn nnnnnnnnnnnnnnnnnnnnttattaaatttcggcccttaacccagccttttccagtgtg taacccagtttgaaatcttaaaaaaagaaaaaatgaaaaaaaaaggaaaaaaagaaaaaa ggaaaaaaacagtttgaacacaannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnctctgcatgcaacagtaaaaattaatat atattttccccacaaaagaaacactt aacagaggcaagtgcaatttataaatttatatctaaaggggaatcatgattataagtcct tcagcccttggactctaaattgaggggattaaaaagantttaaaataattttgaannnnn ttntnttnnncncnnnnnntnnnngnnnnnnnannncattaattcaagacaaatccatgt ggcttgagg

>34748_at HG-U95Av2 tgctcagcaaaattgttgagtacctgttctgggcaggtcccacgc atatgcacaaagtt aagaaaaacttggtcttagcccttngnnnnnnnnnnnnnnnnnngggcattaaggcaaag tagttccagtgatttaaaatacggttccaaatacgctaannnnnnnnnnnnnnnaccaga tttacagattggaaatactgcagatgatgtgaagttatcagttggaggagctgtgattaa gctggataataagagaacgtgccatctgtaaagcactcagaaggcagccatccctagatg ttggtttcatgtatattacactatctactactatccataaatgcaatnata gcatgtta acaacattaaaaacagcaaacagcaatctaagtacagaaaagctttttgtgtgtttaaaa aaattgaagaaaattcaggaagaaacgtgttaataaacattgtactgttcttttgcttct caaaggaantattcacttgccactttggttatttttgagttttcgtacataggaagtttt atattgccagccttcctgtgataaagatattaa

>34759_at HG-U95Av2 caaattgccatgttatggttctgccttgaaacagcacaatgaagtgtatcagtatattct gtgattatgaaacttatatgttgtgttgttttgtgtcttctgttgcctgtcctttgggcc agatgtgnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnttacctaactttttgtatgttttcatgactgtgtgttattttc caaagctgttcctacctcaccatgaggctttatggattgtt

>34760_at HG-U95Av2 cttgtagtgagcagtgtatggtctcttttgttcagaatttaaaactgataaccaatgaaa gccttttctcttattcctctaccgtcatttacatgataatctgaagctaatatgacaata tttaaatactaagtggtactagggaactacaagaatactgtaaagcttaagccattgtta tcactgtcatttagcatttaataacaaaactatacagaattatgtgcataccaatgaatg ttttgtaccatctagttaaattttttaaataaagttttatgggttaagcagaananaann nnnatactgaattttattaaaagtatatatacttcaaattcaaagcatcccttaggaccc acagaatatattaaaactaccacccttaaattttatatttttgctttaagacagacaatg caaaggtaactggcaagaggtgagcaaatgttttagaacatttatattattgcttaaaat gagatttgaaattgtaataaaattcttgnntatgaagtctgatgtcttctctgagcac >34876_at HG-U95Av2 tgaggtgcccaacacccattcatctcaagtgcttcagtctttggtttatttcatgcactg tgccttcaaaatgaaatttttaaaagggactttaaatgaagttgaatagtagtttttaaa agtcaatttgtaatttatgtgaaatctaactgtaatgaggtcctttctgttttttatatg taaacagatctactaatcctgtataaaagttattttacgaanaaaaanaaaaaaaaaaaa nnnnctcataatcttttttcagatgnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnntatttagtttttctgcctatgctagtggaaaaatagtaccaggatcagaatacaggg tatcacctatggaatgtttctgtatttatgaattgactcaaaagaaagctttgtttctga aatcgcat

>34886_at HG-U95Av2 atcatacagatcaggcagtgtttaaaatgatggtaggtagcacagtggacagtctttgat catcatgtagaatatggctatgaatcaggaaagagattagaacatttaataatgtatgta cagctggtgcttagtttttttttaatctaaatttaattaccttattggatatttgatatt tggttatttaatcacannnnnnnnnnnnnnnnnnnnctgattggtgttttatctcctgtg atcctttgatggctttttttgcctaccatttcacagaggtttagacagcagtagtagctc cctaggagagtttactgatgaaacagcctctgcaaga

>34887_at HG-U95Av2 gcactaccatagctacatcagtttgatacagtattgaaaaattatcagttatattttgct gtttatgatctatttgtagattaggattaaaatggatttaatccatttttaaggctgtgt gaatttttctaaacaagaaccatttgcaatatggatttcttagagattaaaccaatta a acttattagcagtcgcgagcacatgttcatatagtcaatgtaaaaatacactaatgagta tttggtaaatcccagtaggcttttaccattagcataattttgtgttgtacaattaagtta caattacatctctaattttggataatattcattggttaacaataaagtgacaaaagctca nnnnnnnaaannnnanngnnnnnannnaacatggattttttgtatgtttcttgaaaat a caatctttatcacagccatgaatcaccacaacttaaaagtaagaagtagataggaaataa ttttaaatcctcatagatntactctttccccgatacctctttggta g

>34916_s_at HG-U95Av2 ccaactgcaccttggctgggaagcacaccctgcagccggccagcaatagctcggacgcaa tctgtgaggacagggaccccccagccacgcagccccaggagacccagggccccccggcca ggcccatcactgtccagcccactgaagcctggcccagaacctcacagggaccctccaccc ggcccgtggaggtccccgggggncnnncggtnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncggagggaccaga ggctgccccccgatgcccnacaagncccctgggggaggcagtttccggacccccatccaa gaggagcaggccgacg

>34975_at HG-U95Av2 cagatctgtca gtatccctaaaaggagggagctggccactggctnttgggaaagccatg ag atatagttagcaaatactgaactttctcagatatggcattagatgcaagacaacctc ctagggattgatgcctaactga ggattctctttgagactatttagatattatgtgagca atttaaagaccagatctaagcaaattttgaaatagatgtttgttttttgtatttctcagt atggaaactaatgctgccactctcatccccgtcccaaccatctctgtcaaaaata acct ttttca atgatattctgagctaatctgataaaatctatgccaatatatactattgcttg tgt

>35017_f_at HG-U95Av2 tacctggagggcacctgcatggagtggctccgcagacacctggagaacgggaaggagacg ctgcagcgcgcggacccccccnaagacacacgtgacccaccnccctnnctctgaacatga ggcataacgaggtnctgggttctgggcttctaccctgcggagatcacattgacctggcag cgggatggggaggaccagacccaggacatggagctcgtggagaccaggcccacaggggat ggaaccttccagaagtgggcggttgtggtagtgccttctggagaggaacagagatacaca tgccatgtgcagcacaaggggcntgcccaagcccctcatcctgagatgggagccctctcc ccagcccaccatccccattgtgggtatcattgctggcctggttctccttgg

>35025_at HG-U95Av2 tttctggaggtctctgaacccagggaagacaagaaggaaagattttgttgttgtttgttt atttggtttccccagtagttagctttcttccctggattcctcacttttgaagagtgtgag gaaaacctatgtttggcgcttaagctttcagctcagcttaatgaagtgtttagcatagta cctctgctatttgctgttattttatctgctatgctattgaagtttnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnntaatcttacaaagtgtcttggaattgtaggtgact attatttttccaagaaatatcccttaagatattaactgagaaggctgggggtttaatgtg gaaatgatgtttcaaaaggaatcctgtgatggaaatacaactggtatcttcactttttta ggaattgggaaatattttaatgtttcttggggaatatgttagagaattcccttactcttg attgtgggatac atttaattatttcactttagaaagctgagtgtttcacaccttatcta tgtag

>35153_at HG-U95Av2 tacattctagatgcaagtctcttgtcggatatangtattgagatattacacctagtctgt ggcttgactgttttctttatgtcttttgatgaatagaagttttaaattttgacaaggtca aatttatttttttcttttgtttgatattttttctctccaatttaaccccaagatttcaga tattctgctctattatataaactttatatttttatatttgtgatctaccttgaattgata tgtatgttgtgaattatggatcagggttctttttttcccccatacaagtatccagtcatt gtaacactgtttattg

>35168_f_at HG-U95Av2 taaatggccaaagcttataggactctgtgacaggttgt

>35261_at HG-U95Av2 cgcctagaagacagcggaactaagaaaagaagaggcctgtggacannnnnnnnnnnnnnn nnnnnnnnnnnnnnnncgaggtagacccagagctaacagaaaagctgaggaaattccgct tccgaaaagagacagacaatgcagccatcataatgaaggtggacaaagaccggcagatgg tggtgctggaggaagaatttcagaacatttccccagaggagctcaaaatggagttgccgg agagacagcccaggttcgtggtttacagctacaagtacgtgcatgacgatggccgagtgt cctaccctttgtgtttcatcttctncnnccctgtgggctgcaagccggnaacaacagatg atg atgcaggnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncaaaggtgttcgaa atccgcaccactgatgacctcactgaggcctggctccaagaaaagttgtctttctttcgt tgatctctgggctggggannnnnnnnnnnnnnnctgagtcctcaaggtgactggggact

>35280_at HG-U95Av2 gatgcgcatcaatgtat tta cttattttctcaatctcctctctctttcctccacccat aataagagaatgttcctactcacacttcagctgggtcacatccatccctccattcatcct tccatccatctttccatccattaccnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntaaatttaaacttacaaacnnnψit tgncacaagtggtgtttattgcaataaccgcttggtttgcaacctctttgctcaacagaa catatgttgcaagaccctcccatgggggcacttgagttttggcaaggctgacagagctct gggttgtgcannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnntaacaccagtgggaattgctggaggaaccagaggcacttc caccttggctgggaagactatggtgctgccttgcttct

>35281_at HG-U95Av2 ataagcaacttcacagaacacgagacagcttgggaatcnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnngacagttttaagcagaggaataacatcaccactgtatatttcag aaagatcactagggcagcc

>35320_at HG-U95Av2 gttcttgttcttcttaaatgtgacatgaaataattgtgctgctacattatactggaaatt aacaggggaaaagggaagagctcttggctcccttgaggttctgctagtggtgttaggagt ggttacaactgagcttttagtaaccatttaaccgtatgtaaacttggtttctaattaaaa aaaaatttctttttccaaaaaannaannnnnnnnnnnnnttaannnnnaantnntttntn nanannnntacaacaactttgatacaaaaatactgaaacagcaactaccacctggaatgg cacactaagtccacactgttaggattttctccttagaaag

>35350_at HG-U95Av2 taatgaggctcctccgctctggacacaacccttt a agattaatttctctgccaattaa cttgtcattttcagtacatattttactattccacaccaaccataattacaacaagggatt tttcttatgcactcctatgcatgtgaataacatgtggtgtaattctgcttcttacagaag tattactgaaggtattatttccaatattatttggtttattatgcggatcttttttatata tgcagtcccatcccttctgtgccactcaatgccatccagacatggtttttccctccaggg gcctnnnntctccagagggcacttcggctgcctctgcttcctctcattcgaggcccggct cttgctgacagaataggttccgttctgggcggtggttctcgagcctgccattcaaaacca aagcaaattggagcatttctcacaacatggtattgaagttcctttttgttctcaaaagtt gtgaccgtgttaaattgtactcccttagtcctgtaag

>35366_at HG-U95Av2 aatggtacattttgccaaagaccacttatacttgagaacatggaagaatttgcctgatac tctctttggggaaaagagtctctcctcttttcctcaaaccccagtacactcagcctctct gnccccaccttctccntgactttngtcctcacttngcttctgcagtancattggaacctn gaattngaaagaaagtcttccttngaataattnggagtttgtcttgagaggcaaatatag ccccaagaatcacaagattcgaggaccatgtaggtcttttacgtagcccaaatccataaa ttagtctcactttttgta ttatcgtttca attaaaccctcta atcaaatgttcatca tgattttgtatgatttttataactattttattcattttattagatttattctaaaatttt ttaatggtaaattcttaaactgtggaaaccactgaaggtgcttat aactgttctcccag atttgtacaagtattggatgattccttgagtttacagc

>35367_at HG-U95Av2 acaattctgggcacggtgaagcccaatgcaaacagaattgctttagatttccaaagaggg aatga gttgccttccactttaancccacgcttcaatgagaacaacaggagagtcattgt ttgcaatacanaangctggataataacntggggaagggaagaaagacagtcggttttccc atttgaaagtgggaaanccattcannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngaa atcagcaaactgggaatttctggtgacatagacctcaccagtgcttcatataccatgata taatctgaaaggggcagattaaaaaaaaaaaaagaatctaaaccttacatgtgtaaaggt ttcatg

>35372_r_at HG-U95Av2 tatttgtgcaagaatttggaaaaatagaagatgaatcattga tgaatagttataaagat gttatagtaantttattttattttagatattaaatgatgttttattagataaatttcaat cagggtttttagattaaacaaacaaacaattgggtacccagttaaattttcatttcagat anacaacaaataattttttagtataagtacattattgtttatctgaaattttaattgaac taacaatcctagtttgatactcccagtcttnnnnnnnnnnnnnnngttggtagtgctgtg ttgaattacggaataatgagttagaactattaaaacagccaaaactccacagtcaatatt agtaatttcttgctggttgaaacttg

>35396_at HG-U95Av2 aaatcctgcccaaaatgtgaagcttggttgactgatgtteatgatagaaagaataaaatg tttctctctctctannnnnnaaaannnaanagtttatttctgtgaaagaagtatttaaac tttcaatattttaactttttgtttttatttcttttagaaaaggccaatatacctatcncn ctttggaagtaaaaatacacactttcgtgtgtacctaaaaaaaaaatcgttgaaaatcaa ggccaaaggtagtgcaattttttcattaagatttaaaaaaaagggaatgatagtctttga aagaaaacagtaggcatccagcactggacaaaacatgggtatcaaagatgaataatcttt ggagattctggcagtgttttcccagaacaagtcaag

>35410_at HG-U95Av2 ccctaggatgctatttaagttgtactgtattagaacactgggtgtgtcataccgttatct gtgcagaatatatttccttattcagaatttctaaaaatttaagttctgtaagggctaata tattctcttcctatggttttnnnnnnnnnnnnnnnnnttagtatggcataatgtcatgat ttactcattaaactttgattttgtatgctattttttcactataggatgactannnnnnnn nnnnnnnnntatacactttagatagatgaagaagcccaaaaacagataaattcctgattg ctaatttacatagaaatgtattctcttggttttttaaataaaagcaaaattaacaatgat ctgtgctctgaaagttttgaaaat tatttgaacaatttgaa ataaattcatcatttag tcctcaaaatatatacagcattgctaagattttcagatatc

>35414_s_at HG-U95Av2 gccttctactggtgcctgcggaagcggcggaagccgggcagccacacacactcagcctct gaggacaacaccancaacaacgtgcgggannnnntgaannnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnncaacacggtccccannnagnantangngaacaagttgagctatgactta acatagccaaaatgtgagtggttgaatatgattaaaaatatcaaattaattgtgtgaact tggaagcacaccaatcttactttgtaaattctgatttcttttcaccattcgtacataata ctgaaccacttgtagatttgatttttttttttaatctactgcatttagggagtattctaa taagctagttgaatacttgaaccataaaatgtccagtaagatcactgtttagatttgcca tagagtacactgcctgccttaagtgaggaaatnnnnnnnnnnnnnnnaagttcnnnnnnn nnnnnnnnnataaaacagagtaatcttgttggttcaccattgagaccgtgaagatacttt gtattgtcctattagtgttatatgaacatacaaatgcatctttgatg

>35628_at HG-U95Av2 gcctctg catctgcc catcaa gct ntggttactacatctnccgtggggncgaattc cnagaaaaacacttnccgaaagaatccttctgaccccagagtggctgggcttgagaccat ctctacagccacagggcggaaactgctggtgtctgggtggtggggtatggtccgccatcc caactatcttggagacetcatcatggctctggcttggtccttgccntgcggggtgtcaca cctgctgccctacttctacctcctctacttcaccgcgctgctggtgcaccgtgaggcccg ggatgagnnnnnnnnnnnnnnnnnnnnnnnnnnggcctggcaggagtactgccggcgtgt gccttaccgcatcatgccctacatctactgaagcggctccaccaccccaggtggggncat gtgcccactca ccaccagcacacccaggaccaggagcctcgacacacttgggactcaag ggcttgcaccccacccagccctgaggatgaacaacctcag

>35638_at HG-U95Av2 tcacttttgcaagttccacagagtaagacattgggtctat ccagctcattcattttata ttgaaaaaaataattttaaaaatggtggcttcagctccagcccctttccaaaatttttca accccaccctgtttggatttttaattaaaaactagtagttctcttggtgttaaaacactt ctgtcctgtgaggtttcccaatggtgtttttcttgtaaatgtgttggacaaatgtgaaga tgcattgtagtttaaccatatgcccacatttagtctctttattcctagttggtgagaaac ctgt

>35664_at HG-U95Av2 gtacactcaagtctaagaatatatgagtggatcatttaccgccccccgccccacnnnnnn nnnnnnnnnnnnnnngtcnttttnnnnaataangtattcttctatggtagtannnnccta cagatctgnnncccttcttcttctaangggtaagtcataatctgtgtaatact caattt atgggatgctcactatgccctgtttctcttctaaacaatttacatgtaatgtctcattcc tcacaataacccttgtaaagtgggcatgattanccatgatttttatagttgaagaaccta agacacagagaccaaggcccatgagctcatagggctgaggcaggatttggaatcaggcca tgtcttctccagagcccacatccatcctttctctatattgcctcccacagatgtgctaaa atttatttaactaatcctttatcctctatttgtgttgtctcccattttttattattacaa tattactgtggtgaacatgc

>35666_at HG-U95Av2 gaagaaggggccatcacaggatgccacccctgncntgggttgggnnnnnnnnnncacgac cagccccttcctgggtatttattctctatttattggggataggagaagaggcatcctgcc tgggtgggacagccccttcagccccttctcccctccccgcctggccanggcagggccacc ccactctacctccttagctttcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnagagctgacgggaggccccagctctgaggggagggggtccgtg gtanangcctggggccggtagaggctccccagggctcccttatgtccnnnnnnnnnnnnn nngggtgtggatgtaattagctctggggggcagttgggtagatgggtgggggctcctggt ggccttntgctgcccaggccacagccgcctttgggttccatcttgctaataaacactggc tctgggactagaaa

>35702_at HG-U95Av2 aggaatgtgccctggagatcatcaaagggggagctctgcgccaagaagaagtgtattatg acagctcactctggaccactcttctgatcagaaatccatgcaggaagatcctggaatttc tctactcaacgagc at atatggacagat cataaacaagtaggaactccctgagggct gggcatgctgagggattttgggactgttctgtctcatgtttatctgagctcttatctatg aagacatcttcccagagtgtccccagagacatgcaagtcatgggtcacacctgacaaatg gaaggagttcctctaacatttgcaaaatggaaatgtaataataatgaatgtcatgcaccg ctgcagccagcagttgtaaaattgt

>35724_at HG-U95Av2 acttcaaattggacccaggagccaaacattcccaacctatccctaaagggtggacaagct tcatttacacgatatctgnagatgtgtatattgggcccgatgatgcacaacaaaaaatag aacctcatcacacagcagtgcttggagaaggtgacagtgtccangtggagaacaaggatc ccaagagaagccactttgtcttaattgctggggagccattaagagaaccagttatccaac atggtccatttgtgatgaacaccaatgaagagatttctcaagctattcttgatttcagaa acgcaaaaaatgggtttgaaagggccaaaacctggaaatcaaagattgggaactagtgga aagcggaagagcaggtcttgatgtgtcctagaattttgccatttnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnaagcttatttagccggtgcttctaaagaattccacactaacg tgataacatggtttttgtaacaataaatgtaggatatttcctggcacatgcaaa

>35735_at HG-U95Av2 acacggtctatgagcaataatgtgatttctggacatngcccatgtataatcctcactgat gatttcaagctaangcaaaccacctnatacagagatctagaatctctttatgttctccag aggaaggtggaagaaaccatgggcaggagtaggaattgagtgataaacaattgggctaat gaagaaaacttctcttatnnnnnnnnnnnnnnnnattataacttcaatgggacactttag accattagacaattgacactggattaaacaaattcacataatgccaaatacacaatgtat ttatagcaacgtataatttgcaaagatggactttaaaagatgctgtgtaactaaactgaa ataattcaattacttattatttagaatgttaaagctta gatagtcttttctaattctta acactcatacttgaaatctttctgagtttccccagaagagaatatgggattttttttgac atttttgacncatttaataatgctcttgtgtttacctagtatatgtagactttgtcttat gtgtcaaaagtcc

>35766_at HG-U95Av2 tgaggagagcaccacagtggtcaccnacacagtctgctgaggttggagctgctgagacga cgctcacagagctgagacgtacagtccagtccttggagatcgacctggactccatgagaa atctgaaggccagcttggagaacagcctgagggaggtggaggcccnnntacgccctacag atggagcagctcaacgggatcctgctgcaccttgagtcagagctggcacagacccgggca gagggacagcgccaggcccaggagta gaggccctgctgaacatcaaggtcaagctggan nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnggcgaggactttaatcttggtgat gccttggacagcagcaactccatgcaaaccatccaaaagaccaccacccgccggatagtg gatggcaaagtggtgtctgagaccaatgacaccaaagttctgaggc

>35803_at HG-U95Av2 gtgtcattgctaaaacctcactgaacaganngcagccaaggtctgtgttcagcacttggt ctctgttgttacgtaaaataataagcatttaaaatagtttacagannnnntnnnnnngnn cnnttnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntnnnnnnnnnn nnnnnnnnnnnnnnnctttcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnntggcaggagagattaaggtaattacaacactcagttctatgtct tacaagcactttgtcttgtctctgcaagaaaattcgattccagtcatttcccataaaa a cagacattttaccaacataatatgctttgattgatgcagcattatgctttgggcagtatt acaannnnnnnnnnnnnnnnnttctgtatttaaatattgtaaaaagaaaataagttataa ctgttataaagcagaacttttgttgcattttttaaactgttgaagtcactgtgtatgttt gtttggtcaatgtttccgc

>35822_at HG-U95Av2 ggccagactatcaggcccatttgtctccccntgcaccgagggaacaactcgagcntttga ggcttncctccnaactaccacttgccagcaacaaaangnaagagctgctccctgcacagg atatcaaagctctgtttgtgtctgaggaggagaaaaagctgactcggaaggaggtnctac atcaagaatggggataagaaaggcagctgtgagagagatgctcaatatngccccaggcta tgacaaagtcaaggacatctcagaggtggtcancccctcggttcent tgtactggangg agtgagtnccctatgctgacccnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnttcaagttggtgtaatcagctggggagtagtgga tgtctgcaaaaaccagaagcggcaaaagcaggtacctnntcacgcccgagactttcacat caacctctttcaagtgctgccctggctgaaggagaaactccaagatgaggatttgggttt tc

>35824_at HG-U95Av2 tgaaaatggccttggagcattatctttagttacttgaagagtttctagtttttttaaaat acagtttatgttaaaataatttttattaatttagagaagacaatcaatgtctgtgagaaa acggactttcttttggattttctttttgtggtcattgtgagtgattgctttttccttttc ttagtttcacattcttcctttgttctaaaacttagactgacatctagctttgacaatcat agtatgttttattttcctgagggggaataacttataatgctgtttagttttgtactattg gtgtgttggtgaatttttaaactgtgtgctaactgcaataaatt

>35844_at HG-U95Av2 tacagtaaccacatgcggctgtttaaagttaagccaattaaaatcacataagattaaaaa ttnnnnnnnnnnnnnnnntaaccacgtttctagaggcgtcactgtatgtagttcatggct actgtactgacagcgagagcatgtccatctgttggacagcactattctagagaactaaac tggcttaacgagtcacagcctcagctgtgctgggacgacccttgtctccctgggtaggnn ngggggggaatgggggagggctnnatnngnccccagctggggcctgttgtctgggaccct ccctctcctgagaggggaggcctggtggcttagcctgggcaggtcgtgtctcctcctgac cccagtggctgcggtgaggggaaccaccctcccttgctgcaccagtggccattagctccc gtcaccactgcaacccagggtcccagctggctgggtcctcttctgcccccagtgcccttc cccttgggctgtgttggagtgagcacctcctctgtaggcacctctcacactgttgtc

>35938_at HG-U95Av2 aggcagtttgcaatcccatgacaactggatttaaaagtacagtacagatagtcgtactga tcatgagagactggctgatacncaaagttgcagttacttagctgcatgagaataatacta ttataagttaggttgacaaatgatgttgattatgtaaggatatacttagctacattttca gtcagtatgaacttcctgatacaaatgtagggatatatactgtatttttaaacatttctc accaactttcttatgtgtgttctttttaaaaattttttttcttttaaaatatttaacagt tcaatctcaataagacctcgcattatgtatgaatgtta

>35966_at HG-U95Av2 ccatttttaagaagaggtgttccagttctgcatctgataccgtctcctttccctgaagtc tggcacaccatggatgacaatgaagaaaatttggatgaatcaaccattgacaatctaaac aaaatcctacaagtctttgtgttggaa atcttcatttgtaa actctgatttagtttag gataattggttctagaattgaattcaaaagtcaaggcatcatttaaaataatctgatttc agacaaatgc gtgtggaaacatctatcctatagatcatcctattcttatgtgtctttgg ttatcagatcaattacagaataattgtgttgtganannnnnnnnnaaattgctcattaat ttttatttacagattgaaaaagaggcaccgtgtaaagaaaatggcaaaataaatatcttt ccannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnggaannangtagcc ttnnnnattttatgattttttcatatgtggaaatctattacatgtaatacaaaacaaaca tgtagtttgaaggcggtcagatttctttgagaaatc

>35992_at HG-U95Av2 tggagacacacttcccagatcaccgcanngnnnnnnnnnnnnnnnnngntctnggncgtt cnggcntncctgccgggtggcttcttcaatcccgtctccttcccaagctcccggcttttt ctaatcaggcaggcgtctgtcaaccctctcnncnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnntgcgccaacctgtgtggggtcttcttcgggcctccctctccgccncgctcctgctc ctacctgcagcacccccagctccgactccagactctctgcatcaggtctccccactccac gctccgggcgccccaactccaacaccacgtcctgncgcgcaggttctnncccnngcggag gagcgcgcagggtgggcggcttaccatagcaag gatcctgcgatagggaacgcgccctt gccccgaggctgcactaccacaggaaataac

>36057_at HG-U95Av2 aaattctgattggttatgtaccgtcaaaagacttgaagaaatttcatgattttgcagtgt ggaagcgttgaaaattgaaagttactgettnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnaatgtatcatccagagtgatgttatctgtgacagtcacca gctttaagctgaaccattttatgaataccaaataaatagacctcttgtactgaaaacata tttgtgactttaatcgtgctgcttggatagaaatatttttactggttcttctgaattgac agtaaacctgtccattatgaatggcctactgttctattattt

>36059_at HG-U95Av2 gaaggatcttattgcacttgggctgttcagaatgtagaaaggacatatttgaggaagtat ctatttgagcactgatttactctgtaaaannnnnnnnnnnnnnnnnntaaactannnnnn nnnnnnnnnnnnnnnnnnnntgtaatggttttaacgttactcactggagagattggactt tctggagttatttaaccactatgttcagtattttaggactttatgataatttaatataaa tttagcttttcttaatcannnnnnnnnnnnnnnannnatgactaatcctgcacctgctct gtctggcagacccatgctgtggaaaacctgcttacagacatcacttttaagtcctttgtg gatgtgggcacagtgaagagcaataaanantgtgaggttcctgntggagttttcagctca tctggagaagacaggtcgaaggccagagttccttgactgatgaaacctttatttcctctg gaagaaggaatgggtagatggggtttcctctttgagttgc

>36065_at HG-U95Av2 ggcccagcaaggtaatttatggttgagctgatgtcaattggttctngtcttgagtcgact caatttagcccaagtgctgaaacaagaaatgtcatttttttcatcaaagacaccagggca gatttttaagtaaagaaagacaattggacccttaagaatttatgcatttgtaaagttgct gttgatccaaatattttcaagccatgtaatccattggttttgtgggcagtttaataaacc tgaacctttgtgtgttttctaattgtacctgagttgaccatcctttctttttatagtata tttcttgtatgatattttgtaaagctctcacctggttcttttatggggacttttcgtttt tgggcaactccagtgtatttatgtgaaactttataagagaattaatttttccatttgcat attaatatgttcctccacacatgtaaaggcacagtggctccgtgtg

>36103_at HG-U95Av2 agcaggagcctgagccttgggaacatgcgtgtgacctccacagctacctcttctatggac tggtnnnnnnnnnnnnnnnncactgtgggactcttcttaacttaaattttaatttattta tactatttagtttttgtaatttattttcgatttcacagtgtgtttgtgattgtttgctct gagagttcccctgtcccctccncnttccctcacanngngtctggtgacnnnnnnnnnnnn nnnnnnnnnnnnngtaggcagtcatggcaccaaagccaccagactgacaaatgtgtatcg gatgcttttgttcagggctgtgatcggcctggggaaataata

>36149_at HG-U95Av2 tgggcagccagcattcattgtaagttccctctttgaaaactggtgtgtgggtgttcagtt ctgtgtctggtgggta ggacagacagtaatctcctgtgatctgtgctagctgtgaggca gctctggaannnnnnnnnnnnnnnggtttgaaccgtgaacaaaactgtgttttgagttta gctgacattaaagaaaaaagttcatcacgtgactgttaatgtaaacctggttattaaaat aactatgaaattannaaaaaaaaaaaaaaaaannnaaaannnnnnnnnatttaaaacagg agaaatctggtaagttgttaggnttctaaattccttttagtctgttcactgagatattaa atttcagtagacagaacccaaaaagagatttcat tctttctaatcactttggcttctnt ctnttttnttaagtaggtaaaaaccttccttggtgggcacctaagcaggatgcagccaat tagttca gaacccagctgcgga

>36156_at HG-U95Av2 taagtcctttcaattccaccagggccagagcagctccaccactgtgcacttagccatgat ggcaacagaaaccaagagacacaattacgcaggtatttagaagcagagggacaaccagaa ggcccttaacta caccagtgcatcacatctgcacactctcttctccattccctagcagg aacttctagctcannnnnnnnnnnnnnnnnnnnnnnnnnnnnnntttcagctagacaatg atttggccaggcctagtaaccaaggccctgtctctggctactccctggaccacgaggctg attcctctcatttccagcttctcagtttctgcctgggcaatgnccaggggccaggagtgg ggagagttgtga ggaggggagaggggtcacacccaccccctgcctggttnntaggctgc tgcacaccaaggccctgcatctgtctgctctgcat

>36175_s_at HG-U95Av2 tagagcttggttatcggccggcccggtggnttggcaggcagtgctgtgcgctnntcnatg gagaagacctgggcttagcaatctccttagttcttgctacacaggatggtgactggaact aaggctacacagagggtcgcacttggactctganggttgggtgtggaagggggaaaaggg gatggagacctgctnccccagctcttcctgtcagccggtttancatgggaancagggtta ancatctgtgttnaggggaggtncaccttaccctttttcataggggaagagtgtcacact cctggctatctcagggggaatggggaaaagaatctttcaagggcaaagaactcgtgggag gatgtctgttgt tgtaatactcacaatggcttttggttagtgttgaaggtgggaagagc a ttgtaggtccagaagagtgaaagagagggaggggtgcagcaacatgtgcacaggcacg cacanntntgcacgcacacatacaatctgggttatctttgtgctat

>36215_at HG-U95Av2 gtctgatcgatcatgcagatacaatgttggtatttgagaggttagtttttttncctacac ttttttttgccaactgacttaacaacattgctgtcaggtggaaatttcaagcacttntgc acatttagttcagtgtttgttgagaatccatggcttaacccacttgttttgctatttttt tctttgcttttaattttccccatctgattttatctctgcgtttcagtgacctaccttaaa acaacacacgagaagagttaaactgggttcattttaatgatcaatttacctgcatataaa atttatttttaatcaagctgatcttaatgtatataatcattctatttgctttnnnnnnnn nnnnnnnnnnnnnnnaacaccacttcttttcatctgtaccacaccctggtgaaacctttg aagacataaaaaaaacctgtctgagatgttctttctaccaatctatatgtctttcggttn nnnnnnnnnnnnnnnnnnnnnnnnnnngtaaatgctgatattgatttcactggtccatct atatttaaaacgtgcaagaaaaaaataaaatactctgctctagcaagttttgtg

>36227_at HG-U95Av2 taccaaaaccagtgaagtgtaagaaacccagactgaacttaccgtgagcgacaaagatga tttaaaagggaagtctagagttcctagtctccctcacagcacagagaagacaaaattagc aaaaccccactacacagtctgcaagattctgaaacattgctttgaccactcttcctgagt t.cagtggcactcaacatgagtcaagagcatcctgcttctnnnnnnnnnnnnnnnnnnnnn ngtttaaggtgacccaatgattcagcta

>36233_at HG-U95Av2 ctgaaaccaagaaggatctgtatgaacccactcatgggggcaaggtcttgagcatggccc ctgnnctcacctctgtggaaatcattccattccgagtggctgcctacaacaaagccaaaa aagccatggacttcta gatccagcaaggcacaatgagtttgact catctcaggaactc gaatgaggaagctcgcccgggaaggnnnnnnnnnnnnnnnnnnnnnnnnnnnccccaaag catggaaggtcctgacagattattacaggtccctggagaagaactaagcctttggnncca gagtttctttctgaagtgctct

>36314_at HG-U95Av2 aacttctcccggtgcctggagctgcagtgtcagcccgactcctcaaccntgccaccccca tggagtccccggcccctggaggccacagccccgacagccccgcagccccctctgctcctc ctactgctgctgcccgtgggcctcctgctgctggcngctgcnnnnnnnnnnnnnnnncag aggacgcggcggaggacaccccgccctggggagcaggtgccccccgtccccagtccccag gacctgctgcttgtggagcactgacctggccaaggcctcatcctnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnncccttccttgggcccctctcattccctccccagaatggaggcaacgccaga atccagcaccggccccanttacccaactctgtacaaagcccttgtccccatgaaattgta ta

>36344_at HG-ϋ95Av2 tttgcctgagcagctcttggtgggagacatgttcaattacttcctctctctggccattgg ggtctttctgttcccagccttcctcacagcctcnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnncttctgccatggatgaaaactcagagaagaaaaggaagagggccatcaaactcat tgtcactgtcctggccatgtacctgatctgcttcactcctagtaaccttctgct gtggt gcattattttctgattaanagccagggccagagccatgtctatgccctgtacattgtagc cctctgcctctctacccttaacagctgcatcgacccctttgtctattnnnnnnnnnnnnn nnnnnnnnnnnnnnnngcaaagaacgctctcctttgccgaagtgtccgcactgtaaagca gatgcaagtatccctcacctcaaagaaacactccaggaaatccagctcttactcttcaag ttcaaccactgttaagacctcctat gag

>36345_g_at HG-U95Av2 tgttaagacctcctattgagttttccaggtcctcagatgggaattgcacagtaggatgtg gaacctgtttaatgttatgaggacgtgtctgttatttcctaatcaaaaagg

>36377_at HG-U95Av2 ggcgaaagatatctctccattgtgcatctgcctcttttgacgttggaagacacatgtctt actccccaaagggagcccagcactgggagccttcttgatgatctcaaaaataatagctat tcaagaaaatcaccaagnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntg ggagcaacatgaatgttctacaaaagtttaaagcagagattgtttcaaatgggtgtagta gatatt ctgaaaaccaaaaaagagtgagattgtcagtgtaagaatgtgatttaatgttt gtagtgcttacaattttgtgtaccaactggatgactaaaaagagtaaaataatttaatta a agctcatattttatgtgtgaaaacatgttagtgaacatatataatcaaaatagatttc attgct ttgcatagtc

>36445_at HG-U95Av2 cagtacttctggacatgc ctggaggagaaagattggtcctcagatgaccctttctcatg ctgcaggattccatgctactag

>36543_at HG-U95Av2 gggtgcatttctaggacttttctaacatatgtctataatatagtgtttaggttctttttt ttttcaggaatacatttggaaattcaaaacaattggcaaactttgtattaatgtgttaag tgcaggagacattnnnnnnnnnnnnnnnnnnctaatatgctttacaatctgcactttaac tgacttaagtggcattaaacatttgagagctaactatatttttataagactactatacaa actacagagtttatgatttaaggtacttaaagcttctatggttgacattg

>36550 at HG-U95Av2 ggaaccacctatgcttaaaatactgtaaatatgcantgaggtttggcaaaatctattcca tgtgtgatttgcttgtagaaacaattttgaaagccccttgaggaaaataaaaatcaagaa gaacacttttctcccttttccatacaaattaaaacttaacagcatcaaattattgggacc agaaaccaagtaatgtataatgtggcttttgttgagttaaataagatgctatataatgga gaagaatttgaaaatgcacaaaaaaatcaatctacattatcagnnnnnnnnnnnnnnnnn nnnntatgttaaatannnnnnnnnnnnnnnnnnnnnaactatgagggtcttgtatccacg - taacacaggtagttacaaaaacatgttattgtactgtgtaaagatgcatagtcatctcat ttggttggctttgtaccttgtaccttttttagccttggcttttgttgaactagaaccctc agca

>36564_at HG-U95Av2 gcaccgagcccaagtgcccatatgaacctctctgccctagccgagggacaaactgtnnnn nnnnnnnnnnnnnnnnnnnnnnagagtatgaagtggaatgaatgctcctgttctgagaag cacacttgtaactgcatcttttgga

>36578_at HG-U95Av2 tatgccaggaatgtgccccttctctaagaaaatgccctatttgcaggggtataatcaagg gtactgttcgtacatttctctcttaaagaaaaatagtctatattttaacctgcataaaaa ggtctttaaaatattgttgaacacttgaagccatctaaagtaaaaagggaatt tgagtt tttcaattagtaacattcatgttctagtctgctttggtactaataatctnnnnnnnnnnn nnnnnnnntca atatttaatcttaatctgtttatttacaagggaagatt atgtttggt gaactatattagtatg atgtgtacctaagggagtagtnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnactggatttgttgttctttcagaaagctttgaatactaaattatagtgt agaaaagaactggaaaccaggaactctggagttcatcagagttatggtgccgaattgtct ttggtgcttttcacttgtgttttaaaataaggatttttctcttatttctccccctagttt gtgagaaacatctcaataaagtgctt

>36600_at HG-U95Av2 cagatacctcggattgaggatggtaacaattttnggagtggctgtccaggagaaggtgtt tgagctgatgaccagcctccacaccaagnctagaaggcttccacactcaaatctctaagt atttctctgagcgtggtgatgcagtgactaaagcagccaagcagccccatgtnnnnnnnn nnnnnnngctggtgcacgagctggatgaggcagagtaccgggacatccggctgatggtca tggagatccgcaatgcttatgctgtgttatatgacatca cctgaagaacttcgagaagc tcaagaagcccaggggagaaacaaagggaatgatctattgagagccctctctcccannnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntggnnnnnnnnnnnnnnnnncaaac ttgcttctgttgagatttttccctcac

>36658_at HG-U95Av2 gaccttatccacaacccggggcttggaaaggaaggtattttggaatcacaccctccggtt atgttgctccagtaaaatctnnnnnnnrinnnnnnnnnnnnttcttagcatggtgagctga gttcatggcttttttttgtagccagtcctgtccctggnccatccatgtgatggttttgga tggagttaaacttgnatgccagtgggcagtgcatgtggaaagtatcagagtaagncnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnanggttttctttagaatcagaattgta gccagtttctttggccagaaggatgaatacttggatattactgaaagggaggggtggaga tgggtgtggcagtgtatggtgtgtgatttttat ttcttctttggtcatgggggccaagg agaaaggcatgaatcttccctgtcaggctcttacanccacaggcactgtgtctactgtct g

>36659_at HG-U95Av2 acagacgagacaacagcacacaggcagccagccgtnggccagaggntcgaggggnnctca ggggcntcaggcnacccgtnccccacacganngggccccgtngggtgggcctnggccctn gctttnctacngnccaatgttatgnccagctnccatgttctncccaaataccngttgnat gtgaattattttaaaggcaaaacngtgctctttannttttanaaaacactgataatcaca ctgcggtaggtcattcttttgccacatccctatagaccactgggtttggcaaaactcagg cagaagtggagaccnttctagacatcantgtcagccttgctacttgaaggtacaccccat agggtcggaggtgctgtccccactgccccacnttgtccctgagatttaacccctccactg ctgggggtgagctgtactcttctgactgc

>36690_at HG-U95Av2 gactattttcaagcaacctggtccacccaggattagtgaccaggttttcaggaaaggatt tgcttctctctagaaaatgtctgaaaggattttattttnnnnnnnnnnnnnnnnngaaaa taccctcctcaaataacttgcttaactacat tagattcaagtgtgtcaatattctattt tgtatattaaatgctatataatggggacaaatctatattatactgtgtatggcattatta agaagctttttcattattttttatcacagtaattttaaaatgtgtaaaaattaaaaccag tgactcctgtttaaaaataaaagntgtagttttttattcatgctgaataataatctgtag ttaaaaaaaaagtgtnnnnnnnnnnnnnnnntgaaatgtcagactgtaaaaccttgtgtg gaaatgtttaacttt attttttcatttaaatttgctgttctggtattacc

>36691_at HG-U95Av2 cttcagcgccactggctggaaggtgggctgggtcctgggtccagatcacatcatgaagca cctgcggaccgtgcaccagaactccgtcttccactgccccacgcagagccaggctgcagt agccgagagctttgaacgggagcagctgctcttccgccaacccagcagctactttgtgca gttcccgcaggccatgcagcgctgccgtgaccacatgatacgtagcctacagtcagtggg cctgaagcccatcatccctcagggcagctacttcctcatcacagacatctcagacttcaa gaggaagatgcctgacttgcctggagctgtggatgagccctatgacagacgcttcg

>36700_at HG-U95Av2 tacaaactgtgacctcagcttcagagtgtcagggcctcacttgt tagaatgtaatgttc tcctcaaacatttatgttaactctataaacaaatatcgttaagttaaacaagttttcaaa aacaaaacaatttttaaagtaccttaaaattgaggatgttactcagtgttaacacatggg aacaccaaaatattcaataagcctggtcaattctatagtta

>36711_at HG-U95Av2 ttgcacggatctaagttattctccccagccagagcccgngctnnctgctcccngggaaaa gntggcgtantggncctgagctgggntttatatttt tatctgcaaataaatnacatttt atcntanatttagggaaagccngagagnaacaacaaaaaatgtttaagccnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntattgcccggctcct agaatttatttatttcctgacttacagcaagcgagttatcgtcttctgtattttg

>36767_at HG-U95Av2 cagaggtagtctcactgcttgaactangctgagcaatctgaccctatgggtctaggacac agttcctgggaacatcacattcctctgcccttcctgcaggcaggaacaaacagggctgcc ttctggccttgtaagacccttattgctgtcctggaggggctggggacttgtgtctgcggg gatcagagcgcacagggagtgcacatatccaggcaccaggactagggctggagtgagggg ggggtatttcaattaccttctattggtctcccttctctacactcttgtaataaaatgtct atttttaatgtttgtacacaacaatccttctattctagcctgcattgagcttgcatgctt gcataagagcttaagaaccattgatttaatgtaatagggaaaattctaacccaggtatcc aaaaatgtgtaagaacaactacctgagctaaa

>36790_at HG-U95Av2 gagaagttccattcaaagtgccaatgatagagtcaacanggaaggttaatgttggaaaca caatcaggtgtggattggtgctactttgaacaaaaggtccccctgtggtcttttgttcaa cattgtacaat

>36791_g_at HG-U95Av2 ctgagtttgcggagaggtcagtaactaaattggagaaaagcattgatgacttagaagaga aagtggctcatgccaaagaagaaaaccttag atgcatcagatgctggatcagactttac tggagttaaacaacatgtgaaaacctccttagctgcgaccacattctttcattttgtttt gttttgttttgttttnnnnntaaacacctgcttaccccttaaatgcaatttatttacttt taccactgtcacagaaacatccacaagataccagctaggtcagggggtggggaaaacaca tacaaaaagncaagcccatgtcagggcgatcctggttcaaatgtgccatttcccgggttg atgctgccacactttgtagagagtttagcaacacagtgtgctta

>36792_at HG-U95Av2 gaagaagttccattcctttctgattggcacacgtgcagctcatgacaatctgtaggataa caatcagtgtggatttccactcttttcagtccttcatgttaaagatttagacaccacata caactggt >36825_at HG-U95Av2 cttggtttcactagtagtaaacattattattttttttatatttgcaaaggaaacatatct aatccttcctatangaangaacagtattgctgtaattccttttcttttcttcctcatttc ctctgccccttaaaagattgaagaaagagaaacttgtcaactcatatccacgttatctag caaagtacataagaatctatcactaagtaatgtatccttcagaatgtgttggtttaccag tgacaccccata tcatcacaaaattaaagcaagaagtccatagtaatttatttgctaat agtggatttttaatgctcagagtttctgaggtcaaattttatcttttcacttacaagctc tatgatcttaaataatttacttaatgtattttggtgtattttcctcaaattaatattggt gttcaagactatatctaattcctctgatcactnnnnnnnnnnnnnnnntattaaatgtaa ggcacttttctatgaattttaaatataaaaataaatattgttctgattattactgaaaan annnnagccatttcaatgtcttgggaaacaa

>36852_at HG~U95Av2 ccacggctatccttatagtgatctggactttgagtgagaagatgtgatttggaccatggc acttaaaaactc at

>36879_at HG-U95Av2 cgagccctgtgctcgggaagtcccgcagaacgccggcagctgctgcctcgcgcccgggag caggaggagctgctggcgcccgcagatggcaccgtggagctggtccgggcgctgccgctg gcgctggtgctgcacgagctcggggccgggcgcanccgcgctgggganccgctccgcctg ggggtgggcgcanagc gctggtcgacgtgggtcagaggctgcgccgtgggaccccctgg ctccgcgtgcaccgggacggccccgcgctcagcggcccgcagagccgcgccctgcaggag gcgctngtactctccgaccgcgcgccattcgccgccccctcgcccttcgcagagctcgtt ctgccgccgcagcaataaagctcctttgccgcgaaaa

>36929_at HG-U95Av2 gtgcccggatccagagtgtgaagacagaggcagaggagctgtttggggagaccatggaga tgatggacaggatgaaagacatggagttggagctgctgcggggcanccnaggccatcatg ctgcgctcagcggacctgacaggactggagaagcgtgtggagcannnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngccng ttnccnnnnnnatctgccgcctttgcttttggttgggggcagattgggttggaatgcttt ccatctccaggagactttcatgnagcctaaagtacagcctggaccacccctggtgtgtag ctagtaagattaccctgagctgcagctgagcctgagccaatgggacagttacacttgaca gacaaagatggtggagattggcatgccattgaaactaagagctctcaagtcaaggaagct gggctgggcagtatcccccgcctttagttctccactggggag

>36965_at HG-U95Av2 aatgcttgccgctttagaggtggatggtgctcataaaaggccccagtcgggggtatttaa aaaggactgaacagaaatccttagctagtagaatggnnnnrinnnnnnnnnnnnnnnnnnt gtattgtgtactggctataagatgtagacacctttcagtaagccaatcatttgtaaccat tctagcagtgtcatattaggttaataaggctgctgtgttttaaagggcatttttatttgg gttttggtgaaattctttaatttgttgattatattcacataaaatcagcattcattgaca catagctctaatgacatatgtatgaaaaaccatacactggatgacctagtcgattatt

>37015_at HG-U95Av2 gtgaaaatctctcagaagaactcataaangaaaatacaagagtggagagaagctcttcaa tagctaangcatctccttacagtcactaatatagtagattttnaaagacaaaatttttct tttcttgantttttttaaacataagctaaatcatattagtattaatactacccatagaaa acttgacatgtagcttcttctgaaagaattatttgccttctgaaatgtgacccccaagtc ctatcctaaataaaaaaagacaaattcggatg atgatctctctagctttgtcatagtta tgtgattttcctttgtagctacttttgcaggataataattttatagaaaaggaacagttg catttagcttctttcccttagtgactcttgaagtacttaacatacacgttaactgcagag taaattgctctgttcccagtagttataaagtccttg

>37027_at HG-U95Av2 gttgcagacggaggtcaggtcttccnnnnnnnnnnnnnnnnnnnnnnnnnnnnagcaaac gcccacagatggcccagaggtggtggtagtcagggtgtgtgggtgtttttagggttcttt agtgttgtttcttnnnnnnnnnnnnnnnnnnnnnnnnnngtttggtgctgacggtgagag gaaattagaatctgtttgcaaattgtccaacccaccccctcaacatgaggggcttccatt ttctgtgttttgtaagggaactgtttccttcatgccgccatgttcctgatattagttctg atttctttttaacaaatgttannnnnnnnnnnnnnnnnnnnnnnnnnntaatggccaatt aactgagaatgtaagaaaattgatgctgtacaaggcaaataaagctgtttattaaccttn aaaaaaaaaaaaaaaaaaaannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnan ncngccatgttcctgatattagttctgat

>37l68_at HG-U95Av2 cagttgctcatttttatgggattgcttagctgggctgtaaagatgaaggcatcaaataaa ctcaaagtatttttaaatttttttgataatagagaaacttcgctaaccaactgttctttc ttgagtgtatagccccatcttgtggtaacttgctgcttctgcacttcatatccatatttc ctattgttcactttattctgtagagcagcctgccaagaattttatttctgctgttttttt tgctgctaaagaaaggaactaagtcaggatgttaacagaaaagtccacataaccctagaa ttcttagtcaaggaataattcaagtcagcctagagaccatgttgactttcctca gtgtt tccttatgactcagtaagttggcaaggtcctgactttagtctta

>37185_at HG-U95Av2 ctcaccctaaaactaagcgtgctgcttctgcaaaagatttttgtagatgagctgtgtgcc tcagaattgctatttcaaattgccaaaantttannnnnnnnnnnnnnnnnnnnctgctct tctgaacaacttctgc acccactaaataaaaacacagaaataattagacaattgtctat tataacatgacaaccctattaatcatttggtcttctaaaatgggatcatgcccatttaga ttttccttactatcagtttatttttataacattaacttttactttgttatttattatttt atataatggtgagtttttaaattattgctcactgcctatttaatgtagctaataaagtta tagaagcagatgatctgttaatttcctatctaataaatgcctttaattgttctcataatg aagaataagtaggtatccctccatgcccttct

>37187_at HG-U95Av2 cgcctaatgtgtttgagcatcacttaggagaagtcntctatttatttatttattnattna tttgttngttttagaagnttctatgttaatattttatgtgtaaaataaggttatgantga atctacttgcacactcncccattatatttattgtttattttaggtcaaacccaagttagt tcaatcctgattcatatttaatttgaagatagaaggtttgcagatattctctagtcattt gttaatatttcttcgtgatgacatatcacatgtcagccactgtgatagaggctgaggaat ccaagaaaatggccagtnagatcaatgtgannnnnnnnnnnnnnnnnnnngtctattttg taactgtaaagatgaatgtcagttgtta ttattgaaatgatttcacagtgtgtggtcaa catttctcatgttgaagctttaag

>37218_at HG-U95Av2 gtgtaccagatttcagaact atatttccacctcttccaatgtggcaccctttngcccag aaaaaagnccaggaatgtantcgagggaatggccatcagaatcac atcctcctcctgtt ccatttggttatccaaatcagggaagaaaaaataaaccatatcgcccaattccagtgaca tgggtacctcctcctggaatgcattgtgaccggaatcactggattaatcctcacatgtta gcacctcactaacttcgtttttgattgtgttggtgtcatgttgagaaaaaggtagaataa accttactacacattaaaagttaaaagttcttactaatagtagtgaagttagatgggcca aaccatcaaacttatttttatagaagttattgagaataatctttcttaaaaaatatatgc actttagatattgatatagtttgagaaattttattaaagttagtcaagtgccgaagtttt taatattggacttgagtatttatatattgtgcatcaactctgttggatacgagaacactg tagaagtggacgatttgttctagcacctttga

>37221_at HG-U95Av2 tttatggtcccacttgtatatgaaaatgtggttagaatgttaattggataatgtatatat aagaagttaaagtatgtaaagtataacttcagccacatttttagaacactgtttaacatt tttgcaaaaccttcttgtaggaaaagagagctctctacatgaagatgacttgttttatat ttcagattttattttaaaagccatgtctgttaaacaagaaaaaacacaaaagaactccag attcctggttcatcattctgtattcttactcactttttcaagttatctattttgttgcat aaactaattgttaannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnagaactttgacca aggctataaannnnacnnacattattttcagtattgttggttatatttaaattttcctta caataaagcacacttttataatnaaaannngaattattgtttttcatacttttttgcttg tttcttaaagttttctgacgtgc

>37241_at HG-U95Av2 catgacatctggaacacagaaagccctcaatacattgaagctcttaggattttcacgatg ttcctgtctgctcaatgcatgctttctttattgttctgacagttgtgtggtaacaagcta atatgcttccagttgacttccagtctaccctggtgttagaaaccgtttcatctcttattg taaatttgagtgcttgttgttttttatatttgtgatgannnnnnnnnnnnnnnttgacaa ttgttagaggtttgacttttaaataattacttattttttctgattgtggttcagtttaac tgaagaatatcctgagattgtaagaaaagcattttttaaaaggtatcacttgtgatcatt tatct

>37255_at HG-U95Av2 gcttggacagccagtgccctcgtggnttcgggaagannnnnnnnnnnnnnnnnnnnnnnn ntgtcccagcctcccataccagcaaaatgccccctgcttccctaagggtcaggtccagag cagggcccacaagggggattagagtggcctggnccctccccctctacctcagtagccccc aggcctgagatggctgagaagggaagggtatccttttcccacagttctgggacaaataaa ggggcttcctttggtaccccacataatagtgctaggtacctttgacccatcatcttggga ggtggggaggaatgagagggtccaggcagggtgtaggggaatgtattagtccaatgagat ttccctcttcatccgcagcagtgtatctattctatacctggcta gggagagaccccttg catgggagggaccccttnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnccc ggcctccctaatgtcattcacattgaatggggatgaggtcggacagnngctcatagagcc gagtatgagccctagctgtgggctag

>37286_at HG-U95Av2 caccttttttgctgtgaaactgaaatagtgaacttttctacgtattgacagcagattttt cgatgaaatcttcagagctttgcctatggggcacagtaggcctagtaacctggcatgttt ga atatgtaggtaaagcataatttaaagtaatcccaggtaaagatggccctaaatactt tcatgtctctatattcatttttcacagatccacctgtctcttgaaaatataaaaagacaa aacaggtttgccttggcatcagagagcacaaagattaaaagttactttaaatttgccaat attttgggagaacaataaaactacattttttcctcttccatactggtagatgcgaaattt atctgtgcatgaaagggtcacttctgtaatagtgcaacagatttggtattaaaaattaaa tgtggttttaaaagttcctctctcttttgtaatttatgttcccaattgagtgtgaatgtc caagtaatggtgtatgtaatggtacaggcaaatgtgactggatttc

>37287_at HG-U95Av2 tgtaaatggttctcggagcttctttgggttaaagggtctaatgccaggaacagcatacaa agttcgagttggtgctgtgggggactctggttttgtgagttcagaggatgtgtttgagac aggcccagcgatggcaagccggc

>37288_g_at HG-U95Av2 ctcagggctggttcattggtctgatgtgtgctgttgctctccttatcttaattt gc ga ttgtttgct catcagaagaaacaagggtggtaaat tccagttaaagaaaannnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnagaagaccacaagcctttgaaaaaaggaagtcgaactccttcagacaggactg tgaaaaaagaagatagtgacgacagcctagttgactatggagaaggggttaatggccagt tcaatgaggatggctcctttattggacaatacagtggtaagaaagagaaagagccggctg aaggaaacgaa

>37352_at HG-U95Av2 gatgccaagacttggcctgcagaatgtcaggaatgtgaattaaaagctgctgtttccaga cgctttttattctgagcaccttcactaccttgtatccagttcatctgggaactccttttt gcattttagaaaatggaaagaggcaggaaa tatgataaactcatgtttaacagaaagag tttcactgactaaatgtatgtaattatattttgttgttgtagaagaaataaatagcaaat ttgtggta tcttttttttaaacctgctctcattcctattaacactaagatcttagattt ttatagtgataaatgggttgacatcattgtcatttgtaattgtaaagcctcaaaagacaa ctgttcctactatgtaattatagacag

>37353_g_at HG-U95Av2 aagcaagcatggtgagaaggctcctatgacttctagaagtacatctac ggagaatacc cagcaggaagagacgtttcagcagtagtgacttttcagacctgagtaatggagaagagct tcaggaaacctgcagctcatccctaagaagagggtc

>37354_at HG-U95Av2 ttctactttggaaaaacacagtgggaaaagaagaaaaaagagaaggcatagatctaaagt aaatggtctccaaagagggagaaagaaagacagacctagaaaacatttaactctgaataa caaagtccaaaagaaaagatggcaacaaagaggaagaaaagccaacactagacctttgaa aagaagaagaaaaagaggtccaagnatncccnaagntgaaaatattaattttaaacaatc tgaacttcctgtnacctgtggtgaggtganggncactctatntaaggagcgattcaaaca aggaacctcaaagaagtgtntacagngtgaggataaaaagtggttcactcccagggaatt tgaaattgaaggagaccgcggagcatccaagaactggaagctaagtatacgctgcggtgg atataccctgaaagtcctgatggagaacaaatttctgccagaaccaccaagcacaagaaa aaaggtgatnnnnnnnnnnnnnnnnnnnaatgtctcgtctattatgttgttgattttcta tctctgtggacttac

>37377_i_at HG-U95Av2 ctctgtgcagtcactggaggttgaagccaagtggggtgctgggaggagggagagggaggt cactggaaaggggagagcctgctggcacccaccgtggaggaggaaggcaagagggggtgg aggggtgtggcagtggttttggcaaacgctaaagagcccttgcctc

>37383_f_at HG-U95Av2 cctttgtgacttcaagagcctctggcatctctttctgcaaaggcanctgaatgtgtctgc gtncctgttagcataatgtgaggaggtggagagacagcccacccnngtgtccacngtgac ccctgtncccannctgacctgtgttncctccccnntcatctttcntgttccagagangtg ggnctggatgtctccatctctgtctcaa

>37388_at HG-U95Av2 ttgacaaatgta atgcctgagaactttgaatgatgc gaaagctagaagcaaaccaggt actcttcagtcagggactggttgaagattttatggatgaggagttagcaaaatatcta a tatgcatatcttctgactcccagggatacataagaaacacagggcctagaacagtatgaa taaacacacatatacacaaacatcacagaagatactaaaggtat

>37393_at HG-U95Av2 tcccgatggccagtttgctttcctcattcccaacggggccttcgcncacagcggccntgt catccccgtctacaccagcaacagcggcacctccgtgggccccaacgcagtgtcaccttc cagcggcccctcgcttacggcggactccatgtggaggccgtggcggaactgaggggnnnt caggccnacccctcctcctaaactccccaacccacctctcttccctccggactctaaaca ggaacttgaatactgggagagaagaggacttttttgattaagtggttactttgtgttttt ttaatttctaagaagttactttttgtagagagagctgtattaagtgactgaccatgcact atatttgtatatattttatatgttcatattggattgcgcctttgtattataaaagctcag atgacatttcgttttttacacgagat

>37402_at HG-U95Av2 aaaggtcacctgcaagaacgggcagggcaactgctacaagagcaactccagcatgcacat cacagactgccgcctgacaaacggctccanggtanccccaactgtgcataccggaccagc ccgaaggagagacacatcattgtggcctgtgaagggagcccatatgtgccagtccacttt gatgcttctgtggaggactctacctaaggtcagagcagcgagataccccacctccctcaa cctcatcctctccacagctgcctcttccctcttccttccctgctgtgaaagaagtaacta cagttagggctcctat

>37417_at HG-U95Av2 ccgctcttcttgaatcatgctgggctgcccctgctcagcaccccgcctggtgtgggcctg gtctcagcagcggctgcggctgtggcagcctccatctccagcaagtctcctggcctctcc tcctcatcctcttcatcctcatcctcctcctcctccacttgcagcgagacggcagcacag acccctggaggtccaggggggcccgaggcagggtccaaacctgagtgagggccagccatg cctcccctcccattcctctggtccctgccttggtcccttgcctgggaagagggcgaggag gccagtggtggggacncagagggtcctcagagcaggagtgacaagggaggaaagaccaaa aaaacaaccaaccaaaaaaaaaaaaaaaaaaggaaagaaactaaccaacaaaagagaaaa ccaaaaataatcacaacagaaaccagctgccccaaaggaaccagaggtga

>37 19_g_at HG-U95Av2 gagaaacgcatcaacccctgcagtgcggcccccatgctgcccagcccagggaagccggcc agctacagcccccatatggtcacaccccaagggggcgcggggaccttaccgttgtcccaa gcttccagcagtctgagcacaacagttactaccttatcctcagctgtggggacgctccac cccagccggacagctggagggggtgggggcgggggcggggctgcgccccccctcaattcc atcccctctgtcactcccccacccccggccaccaccaacagcacaaaccccagccctcaa ggcagccactcggctatcggcttgtcaggcctga

>37420_i_at HG-U95Av2 cgcagatcctccaaaggcacacgttgcccaccaccccatctctgaccatgaggccaccct gaggtgctgggccctgggcttctaccctgcggagatcacgctgacctggcagcgggatgg ggaggaacagacccaggacacagagcttgtggagaccaggcctgcaggggatggaacctt ccagaagtgggccgctgtggtggtgccttctggagaggaacagagatacacatgccatgt gcagcacgaggggctgcccnagccncnnatcctgagatgggagcagtctccccagcccac cannnnnnnnnnnnnnnntcgttgctggccttgttgtccttggagctgtggtcactggag ctgtggtcgctgctgtgatgtggaggaagaagagctcagatagaaacagagggagcnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnggtgtctctcacagctaataaag tgtgagacagcttccttgtgtgggactgagaagcaagatatcaatgtagcagaattgcac ttgtgcctcacgaacatacat

>37421_f_at HG-U95Av2 ccgcagatacttggagaatgggaaggagacgctacagcncgcagatcctccaaaggcaca cgttgcccaccaccccatctctgaccatgaggccaccctgaggtgctgggccctgggctt ctaccctgcggagatcacgctgacctggcagcgggatggggaggaacagacccaggacac agagcttgtggagaccaggcctgcaggggatggaaccttccagaagtgggccgctgtggt ggtgccttctggagaggaacagagatacacatgccatgtgcagcacgaggggctgcccna gccncnnatcctgagatgggagcagtctccccagcccaccannnnnnnnnnnnnnnntcg t gctggccttgttgtccttggagctgtggtcactggagctgtggtcgctgctgtgatgt ggaggaagaagagctcagatagaaacagagggagcnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnggtgtctctcacagctaataaagtg

>37423_at HG-U95Av2 ttcataaatgttctatacagtggacagccctccagaatggtacttcagtgcctagtgtag taactgaaatcttcaatgacacattaacatcacaatggcgaatggtgacttttctttcac gatttcattaatttgaaagcacacaggaaagttgctccattgataacgtgtatggagact tcggttttagtcaattccatatctcaatcttaatggtgattcttctntgttgaactgaag tttgtgagagtagttttcctttgctacttgaatagcaataaaagcgtgttaactttttga ttgatgaaagaagtacaaaaagcctttagccttgaggtgccttctgaaattaaccaaat

>37452_at HG-U95Av2 tagagactcaactatccaagtggtggagaatggggagtcctccnagggccgattttccgt ccagatgttccggtttgctggaaactatgacctagtctacctgnactgtgaagtctatct ctgtgacaccnnnnnnnnnnnnnnnnnnnntacctgctctgggaccagattccgaagtgg gagtgtcatagatcaatcccgtgtcctgaacttgggtcccatcacacggaaaggtgtcca ggccacagtctcaagggcttttagcagcttgnnnnnnnnnnnnnnntggctgcctctgct tctctcggccaccttgaccctgacttttcagtgactgacagcggaaagccctgtgctcca tggctgccatctcacctcctgctgggcagggggcatgatgcgggccagtgctccagccac agaaaagaaagttcatgctttgttcagcctgccttct

>37459_at HG-U95Av2 gagaccgggtgttcctccagatgccctcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnntccactcctcnnnttcnnnntanntattgtatcccatgtaanannnnnnnnannnna aanaaanaaannannnnnannntatagaagaaaatgacacaccaaaaaatccaaatgaaa aacataattgcttcaaaacacttacacagttggaaagttatatgtaagtgaaaatttgga ccattgtgtacaaataaaaactaagatgcatgtttaatactccananannngnnnngnaa nnncgaatgantgggatagagttatgtatcaagtactgacacttggttgtacccactgga atcatattagctgttttatgttatatgcttccacagtaacctgcttattcagatcagtca aaatatatcagtatgaaagatcatagctaatgaaaggcactcactcatattgtttacttt aaaatatttataaatangccttaaagaaatacaaatgatancaattananannnnannna nnnnnntaatttcctctgtatttgtgtagatactttg

>37461_at HG-U95Av2 cgctcaaggccacaaccatgatgatncgaccagcagatttctaaacatcccagtccacct gaggaactgtctcgaactattttcaaagacttaagcccagtgcactgaaagtcacggctg cgcactgtgtcctcttccaccacagagggcgtgtgctcggtgctgacgggacccacatgc tccagattagagcctgtaaactttatcacttaaacttgcatcacttaacggaccaaagca agaccctaaacatccataattgtgattagacagaacacctatgcaaagatgaacccgagg ctgagaatcagactgacagtttacannnnnnnnnnnnnnnnnnaagaatgttatgtgcaa gtttatcagtaaataactggaaaacagaacacttatgttatacaatacagatcatcttgg aactgcattcttctgagcactgtttatacactgtgtaaatacccatatgtcctgaat >37484_at HG-U95Av2 tcttctgacatcagccaagtcaatgtttcgcttatcttgtggaaaccaacttttataaaa tcatatttttccagcttaaatcttactat aggggagaacttcnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnna atccaaagatggg ctaccgggcagagtgccattatgggtcatcctgctgagtgcttttgccggattgttgctg ttaatgctgctnnnnnnnnnnnnnnnnnnnattggattcttcaaaagaccactgaaaaag aaaatggagaaatgaaatattttacgaaagaaaataataacaattattcaataatctann ntcannnnnnnnnnnnnnntgtgacaagaaatgtataattcatgacatagtcatgtaact atgtaatccatcagggattcattacttggaaaatgacaggtcatgcattatccaa

>37493_at HG-U95Av2 caaagcagtgtttgtcctaatttatatattgtttttctagttcattttgtgtttccaact tttca gtaaaattttaattatttttgaatgtgtggatgtgagactgaggtgccttttgg tactgaaattctttttccatgtacctgaagtgttacttttgtgata aggaaatccttgt atatatactttattggtccctaggcttcctattttgttaccttgctttctctatggcatc caccattt ga tgttctacttttatgatatgttttcataagtggttaagcaagtattct cgttacttttgctcttaaatccctattcattacagcaatgttggtggtcaaagaaaatga taaacaacttgaatgttcaatggtcctgaaatacataacaacattttagtacattgtaaa gtagaatcctctgttcataatg

>37494_at HG-U95Av2 gcccccttgggaggtcaacaagcctggggaggtgtgttgagacccccaggcctagacagg caaggggatggagagggcttgccttccctcccgcctgaccttcctcagtcatttctgcaa agccaaggggcagcctcctgtcaaggtagctagannnnnnnnnnnnnnnnnnnnnnnnnn nnggcccccttgaccttcagcaaatcacttctctccctgnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnntttttcctgtcaggttaacttatttgtaggttctgcattat tagaactttctagatatactcattccatctccccctca ttttttaatcaggtttccttg cttttgccatttttcttccttcttttttcactgatttattatgagagtggggctgaggtc tgagctgagccttat

>37514_s_at HG-U95Av2 ctgaacctgtgttcgggcgcctggcatcccccggctttccaggggagta gccaatgacc aggagcggcgctggaccctgactgcaccccccggctaccgcctgcgcctctacttcaccc acttcgacctggagctctcccacctctgcgagtacgacttcgtcaagctgagctcggggg ccaaggtgctggccacgctgtgcgggcaggagagcacagacacggagcgggcccctggca aggacactttctactcgctgggctccagcctggacattaccttccgctccgactactcca acgagaagccgttcnnnnnnnnnnnnnnnnnnnnnncagccgaggacattgacgagtgcc aggtggccccgggagaggcgcccacctgcgaccaccactgccacaaccacctgggcggtt tctactgctcctgccgcgcagg

>37534_at HG-U95Av2 cttttatatgctaaaggagcatctatcagattaagttagaacatttgctgtcagccacat attgagatgacactaggtgcaatagcagggatagattttgttggtgagtagtctcatgcc ttgagatctgtggtggtcttcnnnnnnnnnnnnnnnnngatcaaggatgtagtatctcat agttcccaggtgatatttttcttattagaaaaatattataactcatttgttgtttgacac ttatagattgaaatttcctaatttattctaaannnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnttgttgttgttttnggatggtgttacatattatatgttctagaaacatgtaatcc taaatttaccctcttgaatataatccctggatgatattttt atcataaatgcagaataa tcaaatacannnnnnnnnnnnnnnnnnnnnnnnnnnnnttnnnnnnnnnnnnnnnnnnnn nnnnnnnngttgctgttgtgtgatcaaacatgtctctgtgtagttccagcaa

>37565_at HG-U95Av2 agtccatgagttatatcctggctcagtnggagtgatatttatgtattatttttacttttc tctcagtgtcttatattaagattaacatgttgttaatagttgctttgttgattaatctct cttgttggtgttttaataaatgaaataggcttgcctttagatcgggtgctgatattgcct gtttcctagtaatgggctgatcaaatgatcagtggaattcttggtttgatgataacctta ttaattgaaattttttactgatgtggctttaaaagaggtttattttgtatatgtttagaa ctctctgattttgatgaattatatgggaatgagaaacagaagaagtggtatttgctggcg agttaaataggcaaggtacccagtgataacaccaaccaaaccactcctatcnnnnnnnnn nnnnnnnnnnngatgcctgttgttttactgtgtatattttatttttaatatattaacttt gtggattcatttaaggtctactcaaaagtaacactgtca >37608_g_at HG-U95Av2 ttccagtcagcagaggaagccttgaggggcttgtatggtcgtgtgaggaaaggggctgtg cttgtctgtgcctgggctgaggagggcgccgacgccctgggccctgatggcaaattgctc cactcggatgctttcccgccaccccgcgtggtggatacactgnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnncggcaagaagtgtggcctgcagggctttgatggcatcgtgtgagag caggtgccggctcctcacacaccatggagactaccattgcggctgcatcgccttctcccc tccatccagcctggcgtccaggttgccctgttcaggggacagat

>37611_at HG-U95Av2 ggatcgttatctactgactatattttcccttattactgcttgcagtaattcaactggaaa ttaaaaaaaaaaaactagactccattgtgccttactaaatatgggaatgtctaacttaaa tagctttgagatttcagctatgctagaggcttttattagnnnnnnnnnnnnnnnnnnnnn nnangttactaatatatctgtaacactattacagtattgctatttatattcattcagata taagatttgtacatatta ca cctataaagaaacggtatgacttaattttagaaagaaa attatattctgtttattatgacaaatgaaagagaaaatatatatttttaatggaaagttt gtagcatttttctaataggtactgccatatttttctgtgtgg

>37637_at HG-U95Av2 tccttaaagaactggctgatggggcaggaggtccaggcctgggctctnnnggncctccta gagggccattggagcttgcagctcagacccccnactttgagttttatttatttaaatagt agttggatgcttggcacgtcgtcctgtaataggaaacccttgcctcatcagttttcctga tttacaagtgcaatattttagccaatgccttgggagaagctgccatgcaaaggtggacac cattctccagcttcaggggat tgctcgtcccgggcaccggtggcaggcagctggccttc tggactaaggcagcctggggggacactgcagtctggctacacacagagatcntggcaccc cctgggtggagtgtccctcgggggctttgggaaagcatggcaccctcagaccacacagta gccaagttctggagcaa

>37645_at HG-U95Av2 catttgcactactggaaggagttagatgttggtactagatactgaatgtaaacaaaggaa ttatggctggtaacataggtttttagtctaattgaatcccttaaactcagggagcattta taaatggacaaatgctta gaaattaagatttgtaatatttctctctttttagagaaatt tgccaatttactttgttatttttccccaaaaagaatgggatgatcgtgtatttatttttt tacttcctcagctgtagacaggtccttttcgatggtacatatttctttgcctttataatc ttttatacagtgtcttacagagaaaagacataagcaaagactatgaggaatatttgcaag acatagaatagtgttggaaaatgtgcaatatgtgatnnnnnnnnnnnnnnntaggaaata ttctgtaatcttcagacctagaataatactagtcttataataggtttgtgactttcctaa atcaat

>37695_at HG-U95Av2 gggcctgcgttaaaacctaattgctaatgcttcacaactaggagagcatgccgtcttgat gtttaaaaaacccagggtctccacccttcctttgatttgtgcaattctgtcttccacagt tccggagccttcagtgaggggtagctacatgccccatgcctgccctttctttccttcttt gctcactttactatgggtgtattttaatcttgtataaaaatatnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaaacagatttgat ttgtgtttttgaaatgtcagtacattttgtgccactaacactgtgatgtataaaagagct gtttgaatgccttttaatgttgtgttttgtactctggaatcatatggaaaaagtttgatt tgtaatttcaatacatattttaaatgtannnnnnnnnacgtagtttgtccccccctttag cagggattcctttttaaagct

>37701_at HG-U95Av2 cataaagactgaccttgaattcagcctnnnnnnnnnnnnnnnatcactcagaactattga ttcaaagttgggtagtgaatcaggaagccagtaactgactaggagaagctggta cagaa cagcttccctcactgtgtacagaancgcaagaagggaataggtggtctgaacgtggtgtc tcactctgaaaagncaggaatgtaagatgatgaaagagancaatgtaatactgttggtnc caaaagcatttaaaatcaatagatctgggattatgtggccttaggtagctggttgtacat nctttnccctaaatcgatnccatngttanccacatagtagttttagtttagnnnnnnnnn nnnnnnnngtgtttactatgtgcaanggtattgaagttcttatgaccacagatcatcagt actgttgtctcatgtaatgctaaaacnnnnnnnnnnnnnnnntgcattgttaaaaatgat gtgtgaaatagaatgagtgctatggtgttgaaaactgcagtgtccgttatgagtgccaaa aatctgtcttgaaggcagctacactttgaagtggtct

>37712_g_at HG-U95Av2 gaggatatccatcagccatttcaacaacatatggtaccgagtactctctgagtagtgcag acctgtca ctctgtctgggtttaacaccgccagcnnnnnncaccnnnnnnnnnnnnnnn nnnnnnnnnnnnnnacacctacataacatgccaccatctgccctcagtcagttgggagct tgcactagcactcatttatctcagagttcaaatctctccctgccttctactcaaagcctc aacatcaagtcagaacctgtttctcctcctagagaccgtaccaccaccccttcgagatac ccacaacacacgcgccacgaggcggggagatctcctgttgacagcttgagcagctgtagc agttcgtacgacgggagcgaccgagaggatcaccggaacgaattccactcccccattgga ctcaccagaccttcgccggacgaaagggaaagtccctcagtcaagcgcatgcgactttct gaaggatgggc

>37745_s_at HG-U95Av2 ctgctgtaagctttcttaactgttttttgtaacaagcaaagagaata ggcaaatatttg tatattcccaanggggccgggtgctttcnnnnnnnnnnnnnnnatggatgaagtttcgct gggtgctcgtgactggccnagttttgtgcagctgactgtctcagccaaaccactgatctt ccctggaggccttnnnnnnnnncnnncnngcntnnncctgaggtccccnntnnccagtcn nnnnnnnnnnnnnnnnnnnnnnnnnntgttatgtacaggaggaccttttaaaaaaatcaa gtttctattttttgctggtagtccgcatacccataccctctgtttttgaaaggcaaaggc caatcagtccccatttgtagcatggcaccagggtcttaggcctagtcctctcattcctcc caccctccgagatggtcagtgtgtcatgggaagcccacccccagctctgccagtgctctc tgggcctggctcccagtcagtggtggccacgatgcggtacagggcatccctccttcccat ctacgggtgttctcaataaacaatgtacagttgtttgggcccaga

>37749_at HG-U95Av2 ctctgccagagtagtgaagctaattaaacacntttggtttctgaataaattgaactaaat ccaaactatttcctaaaatcacaggacattaaggaccaatagcatctgnnnnnnnnnnnn nnngttattagctgggaagaccaattctaacagcaaataacagtctgagactcctcatac ctcagtggttagaagcatgtctctcttgagctacagtagaggggaagggattgttgtg a gtcaagnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnt gcctgtcccagagaggctttccaatgtagctcagtaattcctgttactttacagacagga aagttccagaaactttaagaacaaactctgaaagacctatgagcaaatggtgctgaatac tttttttttaaagccacatttcattgtcttagtcaaagcaggattattaagtgattattt aaaattcgtttttttaaattagcaacttcaagtataacaactttgaaactgg

>37785_at HG-U95Av2 ttgggggcctacagcagcctcaccttcagcttcatgcctcttccacacagcgtttccatg caggtcaggggatgggaggggtccctgagcccttcccttcccctctaaggaggcagcaac ggcagagtggggaantgganngnnnnnnnnnctnnntngnntnnnnnnnnccnngnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncagagccnaatgagaaggaaacctcatc tttgcatagcccatgccntcatggagaggtgacatcatacattcacatgcttctcaccta agtccccagggt

>37823_at HG-U95Av2 cccaggtgcagtgtgacattattttattataacanccncaaagagattatttttaaataa tttaaagcataatatttcttaaaaagtatttaattatatttaagttgttgatgttttaac tctatctgtcatacatcctagtgaatgtaaaatgcaaaatcctggtgatgtgttttttgt ttttgttttcctgtgagctcaactaagttcacggcaaaatgtcattgttctccctcctac ctgtctgtagtgttgtggggtcctcccatggatcatcaaggtgaaacactttggtattct ttggcaatcagtgc cctgtaagtcaaatgtgtgctttgtactgc

>37830_at HG-U95Av2 acctgcctgcgctctccagatatganccctgcanccaccccccacagcntgccctacccc acctacnntgcntcagcntnggacttctcagtgggtggagtgccagggaggaggaggcac acggagacctggggctcggggcccctggattcctgcatctgcatatgcgtatttgccaaa gacgacagggtgggctggggtgcgctccggaggaacccccggcactgatgggcttctgcc cctgcccttcctcacactgacactttgtccccacatggggtggggagcagagtgcccgcc ccgtggagatacnnccccagcgggggctgcgacatccatggccaccatggggcacctggc ggggcgggggtctgccggcctctgggcaaggcccctggagcatctcgcccaggcttttta taccttacaatgtaacttttttattttattttactctatgattattcaggaatattatct ctcagataagt

>37841_at HG-U95Av2 gaaagcaggattccatcgctggaacaattacatgatggactggaaaaatcaatttaacga ttacactagcaagaaagaaagttgtgtgggtctctaattaatagatttaccctt a aga acatattttcctttagatcaaggcaaaaatatcaggagcttttttacacacctact aaa aagttatta gtagctgaaacaaaaatgccagaaggataatattgattcctcacatcttt aacttagtattttacctagcatttcaaaacccaaatggctagaacntgtttaattaaatt tcacaatataaagttctacagttaattatgtgcatattnnnnnnnnnnnnnnnnnnnnnt tctttctttccttaataaatttaagttttttccccccaaaattatcagtgctctgctttt agtcacgtgtattttca

>37944_at HG-U95Av2 ccactttga gctatttgggttatgatggggcaagatggcagaggtattgggtttttttg tttttttccattcctctctacttctgtttcctagctttttctttctggagtttaagtaca gtgatggttggcttgagnnccttttnaaatctngcccagtataaacattagcctgcttaa tatttagacatttataggtagaattctgagcactcaactcatgtttggcattttaaagta aaaacaagtgtgacttcgaggaccaaagaaattgtcagctatacatttatctttatgaac tcatttatattcctttttaatgactcgttgttctaacatttcctagaagtgttcttataa aggtctaatgtatccacaggctgttgtcttattagtaaatgcaaagtaatgactttgtct gttttactctagtctttagtacttcaaaattaccttttcatatccatgatcttgagtcca tttgggggatttttaagaatttgatgtatttcaatacactgttcaaaattaaattgttta attttatgtatgagta gtatgttcctgaagttggtcctatt

>38022_s_at HG-U95Av2 tcaacaagggcctggtggacaagatcatggtggaccgcnnnnnnnnnnnnnnnnnnnnnn nnnnnggcttcgaggacccacgcaccaagaccaagatgtcggccgcccaggccctgaaga agggctggctctactacgaggccggccagcgcttcctggaggtgcagtacctgaccggcg gcttgatcgagcccgacacgccgggccgcgtgcccctggacgaggccctgcagnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngctggaccgcagcatggtgg aggagggcacggggctnnnnnnnnnnnnnnnnnnnnnnnnnnccaccaagggctactaca gcccctacagcg

>38062_at HG-U95Av2 aaatcagtgacctgaagcaagaaatcttgccttttaatgtatcattaattagggctgctg tgatattgtcagcttgcattaacaattagaagatagagaacccgccatcagggtgnnnnn nnnnnnnnnnnnngactacacttggtagttttccaccatttaaagaactggtaaatatga aacatttgttgagttaccagaattgccattaacagtgttttctttcccatattccatgct ttctgcctctgtgtatatatataatatatatgtatatgactgtgctgtgtatttatcgaa gctagtaagcaataatttatatgtaaaaatggccaagcaatataaggttaaaact atat aagtaacccttaccttatcttgtattttcaattttttttnaaaactgcttttccaaatat gagactatg

>38066_at HG-U95Av2 ctgatctatacaaattttcagaaggt attttctttatcattgctaaactgatgacttac catgggatggggtccagtcccatgaccttnggggtancaattgtaaacctagagttttat caactttggtgaacagttttggcataatagtcaatttctacttctggaagtcatctcatt ccactgttggtattatataattcaaggagaatatgataaaacactgccctcttgtggtgc attgaaagaagagatgagaaatgatgaaaaggttgcctgaaaaatgggagacagcctctt acttgccaagaaaatgaagggattggaccgagctggaaaacctcctttaccagatgctga ctggcactggtggtttttgctctcg

>38129_at HG-U95Av2 atctccagaaagtggtattccataaaacctaccaactcatggattcccaagatgtgagct ttttacataatgaaagaacccagcaattctgtctcttaatgcaatgacactattcataga ctttgattttatttataagccacttgctgcatgaccctccaagtagacctgtggcttaaa ataaagaaaatgcagcaaaaagaannnnanagaaatatttggtggttttttttttttnnn naaacatccacagttaaggttgggccagctacctttgggnntgacccccnccattgccat aacatcctgctccattccctctaagatgtaggaagaattcggatccttaccattggnaat cttccatcgaacatactcaaacacttttggnccaggatttgagtctctgcatgacatata cttgattaaaaggttattactaacctgttaaaaatnnnnnnnnnnnnnnntttaacagac accctaaaagtctccttttcnacatagttgaagacagcaacatcttcactgaatgttttg

>38130_s_at HG-U95Av2 catattgcttttgctgcattagaagctgtttgtttccaaactcgagagattttggatgcc atgaatcgagactgtggaattccactcagtcatttgcaggttgatggaggaatgaccagc aacaaaattcttatgcagctacaagcagacattctgtatattccagtnnnnnnnnnnnnn nnnnccgaaaccactgcactgggtgctgccatggcggcaggggctgcagaaggagtcgac g atggagtcttgaacctgaggatttgtccgccgtcacgatggagcggtttgaacctcag a

>38152_at HG-U95Av2 agtgctacatgatgccggtgttgaccttccttcaagaggaccaaatgatttcagaattta gttttagcagctgaaaatttatttctccctgtaaacgttaaaaacagttttccaaataac atcaacaacnnnnnnnnnnnnnnnnttcttattctttctaaactacaacgaacacaagaa ttgaatagtaagatgttaattttttttactataaacatttttagagaagtaaaacatgct gaaaactacacaaattataagcatacaactggactcattatcacagtgaatgcactgtgt gatcgccacataggtaaaaactggaatggtcgtaggcctctccatctgtacccttttcca tcatgtcctattccctgtcactacacactaaaactttcctgacttacaataccatgggtt atttatgcttg

>38169_s_at HG-U95Av2 ggatcgtctcccagggtaacctcgaagagtgagtnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnctcttctgcccctcccttctgccaacacagcagtcagcttct ctcgtgagctttctggtaggannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngctg tttcttgttctcttcgttgccatcgttctcaccnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngcatcttggtgaac atttacttgatggtccagttaagtgcagacacttgggtcagattcagcatttggatggca attggcttcctgatttacttttcttatggcattagacacagcctggaggg catctgaga gatgaaaacaatgaagaagatgcttatccagacaacgttcatgcagcannnnnnnnnnnn nnnnnnnttcaagcaaatgaccatcacccaagaaatctcagttcacctttcatattccat gaaaagacaagtgaattc

>38177_at HG-U95Av2 ggcgctgtcctgaatccccacgaggccctggctcagcctcttcccaccacaggcacacca gggtcagaaggggggacggtgaagaactatgagacagctgtccaattttnctggaannnn nnnaannannannnnnnnncnannnnnaaggattggtgcgactgggccatgattagcagg ccttatagcaccctgcgagattgcctggagcactttgnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnatctttgagactcaccagatccactttgccaactgc tccctggntgcagcccaccttctctgaccccccagaggatg actcctggcca gatcat agcccccatctgcctcatccccttcctcatcactcttgtagtatggaggagtaaagacag tgaggcccaggcntagggggcnacgagcttctcaacaaccatgttactccacttccccac ccccaccaggcctccctcctcccctcctactcccttttctcactctcatccccaccacag nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnggtcatggcacaagttctgtaatcttc a

>38222_at HG-U95Av2 cacccagaagaagttccgccggcgaccacatgagctcctacagaaactcacagccaaatg gcagaggcagggtcgctgagtcctccaggtcctgggcagccttcatatttgccattgtgt ccggggcaccaggagccccaccaaccccaaaccatgcggagaattagagttcagctcagc tgggcatggagttaagatccctcacaggacccagaagctcaccaaaaactatttcttcag ccccttctctggcccagaccctgtgggcatggagatggacagacctgggcctggctcttg agaggtcccagtcagccatggagagctggggaaaccacattaaggtgctcacaaaaatac agtgtgacgtgtactgtcaa

>38223_at HG-U95Av2 gcaagacagcagctgcta gcacacntggagtccaccataccaaagcacgaaccagactg tttcttnggggtcagccctanaccgngatttcagtctnnnnnnnnnnnnnnncatctggc taaacaacctgacaaactgtggccaggggaaccgacacaaccctcaagcatttctatgta ttgagaattgtcagtgccctaaggta ccattggttcccttgatgccaacttacaatttt taccggatttgctgaaatgggcacnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn ngaacacaatgtctcatactaaccaagaagcaagaaaagccccatgctttcatttttcac ttggagtgacaatgggagaggtcaggaatcaagttcactttcaagatctaagggagtcca ctatctgtgcaattgtatttggcttttttttgcactgtttcaatgctggtaattgaaacc attttaatatatttggttgtattcactttatatgtccttccaaaaatgttgttgtgtaca naccatgctttcaatgttggcttcca

>38234_at HG-U95Av2 cagccgagcgttcagggctgcgctccggccggctgagagggcacgtgccccgtcacagtc tggactcctgggcctggattgatgtgtctcacagactcggaagggttctgctcctcctcc tccccctgaacaatgctggcagttgctacaaatagatttattggaggcttatggctccgg ttcccccacanacccgctcatgagtctctgtttgttcttcccttttcttttgccctgtcc ctcaccttgggtcgggggtgctggagtggaccacaatgttgtgctgggggatgggggggt ctctctttgccgattgtgcagtgcacaagatttgtgaaaaatgtaaataacagactccta ttgcg

>38247_at HG-U95Av2 cagactgggaacagggcccaggaatctgtgtggtacaaacctgcatggtgtttatgcaca cagagatttgagaaccattgttctgaatgctgcttccatttgacaaagtgccgtgataat ttttgaaaagagaagcaaacaatggtgtctcttttatgttcagcttataatgaaatctgt ttgttgacttattaggactttgaattatttctttattaaccctctgagtttttgtatgta ttat attaaagaaaaatgcaatcaggattttaaacatgtaaatacaaattttgtataac ttttgatgacttcagtgaaattttcaggtagtctgagtaatagattgttttgccacttag aatagcatttgccacttagtattttaaaaaataattgttggagtatttattgtcagtttt gttcacttgt atctaatacaaaattataaannnnnnnnnnnnnnnngaccacatctctt tggaaaatagtttgcaacatatttaagagatacttgatgccaaaatgactttatacaacg

>38267_at HG-U95Av2 gttctaactagtaatcttggccctattcattacatcctctgcttgtcattctgctaattt atgaagatagtttattatagtctgtacttcagttctcatcttgtaaataatgcttaacat aaacttgtacttacactgaaatccaaaatagtcatgtttctgcagtattctgtagccaac ttaaacctgtgctttcatgtttaagaaatgagaaattgtgccaaagatagcagaagagta gataagtgctcagtattgacgacctacatctgaaatctacancataatgatactgaattg ttatgtaaacatcataaatagtaaataatgattcaatgtgaattttaaaatgcaaatatt gct ttgtttataggaaataaatctaaatataaatgaaannnaannnannaantttatct tgggctaaatggttctacccct actaggttgccccaattagtggcactagttggcagag ctgttcannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnac tgctgttaactcataaaagagaagagtgttccatttcagtctcaataa

>38268_at HG-U95Av2 ctca gcatagacaagtgttttgggtttttaaaaaaaatattctgtcattggttacaaat ttttactcaggctttctattggcatggatttcctttgacctctcannnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnccccagttaatgtgccaaaatgtcaatttttaacttatc tccagccaatttcaaagaaaacagaccagcatagnttctgncnatnacngttttnagntg ggcatagggnttggaagaaagggagaaggattcttttttcaatgtactgtattgggacgc tggtaactgttaacccagtgttcagcatagagctatatatatatatatatnngtatatat ttattattttcatatnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaatgtgaaataa agagttctccttgtacttgaataataaccacgnttccaacccaggtctgctttngggctt atcagaactcctttctaag

>38276_at HG-U95Av2 ccggagccataactgctgcagtttgggcccaggctatgtgctcttctggtgccctaggga ctgctgtggccagagcctggggccagccagtacagtcctgagccgaggaggagggactgc aagtggaagagagccagtctggaaggaagagctttccaggtggacagggcttcttggaag acccccaaagccccagg atcctgggtgaagcctgtttgcctctcttgaaaatggcaggt gctcttnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnagtaggaagcatggact ctcctgagtgagaagagactgaaataggagcaagcagaaccctgagaggtgtcccatctt attgctgttgaggaccctgaaacaccgttgtttaaagacttcacacagaaggctctgaac tgagccactggggaa

>38278 at HG-U95Av2 gtaggccagcccatggtgttgtgtacactgtggagtcgacaggggcctacnnnnnnnnnn nnnnnctgccagggggctctgaactagtgcctgctacccaggacacccgggccatncccc tggctgggcagcctggcacaagtgaagaagaaggcagtgggaaaactgggtttatctcaa ggcagcagcctgagcccaggagcagaggacccagttgttataaggcgctgggagaggatn ggcagctcccactgccccagagcggagctcgaagcacccaggttgcccacggaa

>38287_at HG-U95Av2 actggaggaacctccacttgttttggctgctgcaaatgtggtgagaaatatcagctataa atatcgagaggacttgtctgcacatctcatggtagctggctgggaccaacgtgaaggagg tcaggtatatggaaccctgggaggaatgctgactcgacagccttttgccattggtggctc cggcagcacctttatctatggttatgtggatgcagcatataagccaggcatgtctcccga ggagtgcaggcgcttcaccacagacgctattgctctggccatgagccgggatggctcaag cgggggtgtcatctacctggtcactannnnnnnnnnnnnnnnggaccatcgagtcatctt gnnnnnnnnnnnnnnnnnnnnc atgatgagtgaaccttccccagacttctctttct at tttgtaataaactctctagggcca

>38298_at HG-U95Av2 ataccacttgtcagggcacaggggactggctgggccccnagggntgctccccacttgcag cacaatgccttctccacctgccctcccactcttccagtccaatccacgctgtcttctgtt gcaggactaacctttgagaaatccttttgtgaagtcattgcctgctcaagaatgtacagt ggctccccaatgccttggaggccataaggccagccagttctagctctctattacctgtcc ccactcaactgactca acctgtnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncgat gatcgtcacctctgtgcctgagttctccctgttgtctcaaagcggtacccatcctccccc agaagctgtccccagcgagcctcccttctttgtttgaattctctaataagagcaacnnnn nnnnnnnnnnntagaacacatttacagtattactattttctaggatataaagtgccatat atatttttaattccaatattaataaatgtatgccaaacaacaannaaaaaaaaaaannnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnncagctgcaaggaaacacatgagaac

>38299_at HG-U95Av2 tgggcacctcagattgttgttgttaatgggcattccttcttctggtcagaaacctgtcca ctgggcacagaacttatgttgttctctatggagaactaaaagtatgagcgttaggacact attttaattatttttaatttattaatatttaaatatgtgaagctgagttaatttatgtaa gtcatatttatatttttaagannnnnnnnnnnnnnnnnnnnntgtattagttttgaaata ataatggaaagtggctatgcagtttgaatatcctttgtttcagagccagatcatttcttg gaaagtgtaggcttacctcaaataa

>38315_at HG-U95Av2 agcttgcagggagtaaagcaggcccgcctccctttcttcccatccacatactcctcttct gctttccagtgactccaccagtttgatgtgggaagtgttagcttcctttccttcttccat cccttcttccatctttccagctgtcaaatccaatccagtctctaacctanatgcagatca tttatttaaaagtaccaaacataacccagagtntgtggaatatgggcaacata atatag ccttctgtatttaacgatcttctgcttcttaaccgtaccagttttctatttataactctt atctatccatgatgttttaaagtctccacttgctgttatttacaaacgacagtgcattca gcagcccagtgccgtgagccctgacagatgccgtatttctgagtgcttccatgtgannnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnttacctttgga ctgcaacaaaaaatgtgaaaatgaagatttatttcttttaatttacttaaaaagaaacct ctgtgctagcaataaagcatttat

>38326_at HG~U95Av2 gacaggctctccagaagcaagccctgcaggagaaaggcaagcagcaggacacggtcctcg gcggccgggccctgtccaaccggcagcacgcctcctaggaactgtgggagaccagcggag tgggagggagacgcagtagacagagacagaccgagaaggaagggagagacagagggggcg cgcgcacaggagcctgactccgctgggagagtgcaggagcacgtgctgttttttatttgg acttaacttcagagaaaccgctgacatctagaactgacctaccacaagcatccaccaaag gagtttgggattgagttttnctgctgtgcagcactgcattgtcatgacatttccaacact gtgtgaattatctaaatgcgtctaccattttgcactagg

>38332_at HG-U95Av2 cagggtcttgctagtgagctggaccagtgaggcctaccccacacctgggctctccacagc cccatcaaagaacagagaggaggaggagggagaaatggccaccacatcaccccagagaaa tttctggaatctgattgagtctccactccacaagcactcagggttccccagcagctcctg tgtgttgtgtgcaggatctgtttgcccactcggcccaggaggtcagcagtctgttcttgg ctgggtcaactctgcttttcccgcaacctggggttgtcgggggagcgctggcccgnacgc agtggcactgctgtggctttcagggctggnnnnnnnnnnnnnnngaagcctcctgtctcc agctctctccaggacaggcccagtcctctgaggcacggcggctctgttcaagcactttat gcggcaggggaggccgccnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngcatttctcctcagagaagcg ctgtgctaaggtgatcgaggaccagacatt

>38430_at HG-U95Av2 gatgcttttgtaggtacctggaaacttgtctccannnnnnnnnnnnnnnnnnnnnnnnaa gaagtaggagtnggcttnnncnncnaggaaagtggctggcatggccaaacctaacatgat catcagtgtgaatggggatgtgatcanccattaaatctgaaagtacctttaaaaatactg agatttccttcatactgggccaggaatttgacgaagtncactgncagatgacaggaaagt caagagcaccataaccttagatgggggtgtcctggtacatgtgcagaaatgggatggaaa atcaaccaccataaagagaaaacgagaggatgataaactggtggtggaatgcgtcatgaa aggcgtcacttccacgagagttta gagagagcataagccaagggacgttgacctggact gaagttcgcattgaactctacaa

>38433_at HG-U95Av2 tgtttcaaggcactctagattccattggtccaagattccggatcctaagcatctaagtta taagactctcacactcagttgtgactaactagacaccaaagttctaataatttctnaatg ttggacacctttnaggttctttgctgcattctgcctctctaggaccatggttaagagtnc caagaatccacatttctaaaatcttatagttctaggcactgtagttctaagactncaaat gttctnaagtttctaagattctaaaggtccacaggtctagactattaggtgcaatttcaa ggttctaaccctatactgtagtattctttggggtgcccctctccttcttagctatcattg cttcctcctccccnaactgtgggggtgtgcccccttcaagcctgtgcaatgcattaggga tgcctcctttcccgcaggggatggacgatctcccacctttcgggccatgttgcccccgtg agccaatccctcaccttctgagtacagagtgtggactc

>38438_at HG-U95Av2 aggtgctcagagagccggcccgcctgaatcattctcgatttaactcgagaccttttcaac ttggcttcctttcttggttcataaatgaattttagtttggttnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntngcttactaannnnn nnnnnnnnnnnnnnnnnnnnnnntgctttctgttgtcattgctgttgtccctctgctacg ttcctattgtcattaaagg atcacggtcgccacctggcattccttctgaccacagcatc attttgcattcaaattaagggttaagaaaagagatattttaaaatgagagtcacttga g tgccat

>38439_at HG-ϋ95Av2 acacttgggatttttctcctctgtcccgaggtcgtcgtctgctttcttttttgggtttct ttctagaagattgagaagtgcatatgacaggctgagagcacctccccaaacacacaagct ctcagccacaggcagcttctccacagnccccagcttcgcacaggctcctggagggctgcc tgggggaggcagacatgggagtgccaaggtggccagatggttccaggactacaatgtctt tatttttaactgtttgccactgctgccctcacccctgcccggctctggagtaccgtctgc cccagacaagtgggagtgaa

>38453_at HG-U95Av2 cgtggcaatgagactctgcactatgagaccttcgggaaggcnagcccctnctccgcagga nnnnnnnnnnnnnnnnnnacagcacggctgacagagaggatggccaccgcaacttctcct gcctggctgtgctggacttgatgtctcgcggtggcaacatctttcacnaaacactcagcc ccngaagatgttggagatctatgannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnagcggatgggcacctacggggtgcgagcggct tggaggaggctgccccnngnnttccggccatagcaaccatgantngcatggnccnncacc acggtggtcactggaactcagtgtgactcctcagggttgaggtccagccctggctgaagg actgtgacaggcagcagagacttgggacattgccttttctagcccgaatacaaacacctg gactt

>38454_g_at HG-U95Av2 cactggaactcagtgtgactcctcagggttgaggtccagccctggctgaaggactgtgac aggcagcagagacttgggacattgccttttctagcccgaatacaaacacctgg >38463_s_at HG-U95Av2 tgtcaaagtgactgcgttcatcagttttacactggggctgctacataatattttcatttg aacgaagaacttcaaaaagcacaggactagatgatctctgttccttttggctctaatatg ctacaactgtaggccaattatcactttaccaattaagagttaggccagataagtgaaatt tnnnnnnnnnnnnnnnnnnnnnnnnnnnataggcctaaactggatttccttattccaaat cctgtcttttccccactattccattagaccnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaaaatttctccc tatcta ctgtgatgacttcagaagatacaatggtcccaggggccaagtagaaagcatt

>38466_at HG-U95Av2 tcactgtggccatcaggactttccctgacagctgtgtactcttaggctaagagatgtgac tacagcctgcccctgactgtgttgtcccagggctgatgctgtacaggtacaggctggaga ttttcacataggttagattctcattcacgggactagttagctttaagcaccctagaggac tagnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaaggtagaaatgtc tatgttttctactccaattcataaatctattcataagtctttggtacaag

>38488_s_at HG-U95Av2 tgtgctgtcaaaacaagtttttctgtcaagaagatgatcagaccttggatcagatgaact cttagaaatgaaggcagaaaaatgtcattgagtaatatagtgact tgaacttctctcag acttactttactcatttttttaatttattattgaaattgtacatatttgtggaataatgt aaaatgttgaataaaaatatgtacaagtgttgttttttaagttgcactga attttacct cttattgcaaaatagcatttgtttaagggtgatagtcaaattatgtattggtggggctgg gtaccaatgctgcaggtca

>384_at HG-U95Av2 acgccgagatgaccacacggatggtggcgtccaagatggagctacacgcgttatctacgg gccgcgagccccgcgtggccacggtcactcgcatcctgcgccagacgctcttcaggtacc agggccacgtgggtgcatcgctgatcgtgggcggcgtagacctgactggaccgcagctct acggtgtgcatccccatggctcctacagccgtctgcccttcacagc^'cctgggctctggtc aggacgcggccctggcggtgctagaagaccggttccagccgaacatgacgctggaggctg ctcaggggctgctggtggaagccgtcaccgccgggatcttgggtgacctgggctccgggg gcaatgtggacgcatgtgtgatcacaaagactggcgccaagctgctgcggacactgagct cacccacagagcccgtgaagaggtctggccgctaccactttgtgcctggaaccacagctg tcctgacccagacagtgaagccact

>38584_at HG-U95Av2 tattttcctgtcagcatctgagcttgaggatggtagtgagnaaatgggccagggcgcagt cagctccagtcccagagagctcctctctaactcagagcaactgaactgagacagaggagg aaaacagagcatcagaagcctgcagtggtggttgtgacgggtaggaggataggaagacag ggggccccaacctgggattgctgagcagggaagctttgcatgt gctctaaggtacattt tt

>38617_at HG-U95Av2 gagatagctccctgagctgggccatctgacttctacctcccatgtttgctctcccaactc attagctcctgggcagcatcctcctgagccacatgtncnggnnnngnaaancctnnnnnn nnnnnnnnnnnnnnnnnnnnactcttcatcacaactagatttgcctcttctaagtgtcta tgagcttgcaccatatttaataaattgggaatgggtttggggtattaatgcaatgtgtgg tggttgtattggagcagggggaattgataaaggagagtggttgctgttaatattatctta tctattgggtggtatgtgaaatattgtacatagacctgatgagttgtgggaccagatgtc atctctggtcagagtttacttgctatatagactgtacttatgtgtgaagtttgcaagctt gctttnaggnctgagccctggactcccagcagcagcacagttcagcattgtgtggctggt tg

>38631_at HG-U95Av2 gctctaccccaggaaaatgtgagctcgttttcctgctcggcatgtgctccccctaaggct ctgctccnnnnnnnnnnnnnnnngttccttctcagcctgagagggggcccttcgnnctca ggcatgactcagcccnnnnnnnnnnnnnnnngnnnnnnnnnnnnnnnnnnnnnnnnnnnn cttgggtcngtccccttttcccaggtactgccttacaaagctgtggccaggaagtggccg gtataaaggatgcccaaggtctttgtacgtgtgtaggagttagcgtgtttgatattgtta atataataataattattttttagagtactgcttttgtatgtatgttgaacaggatccagg tttttatagct

>38787_at HG-U95Av2 tgccgaaaactcgtcctcccgagagctggatgacagcagcagtgagtccagtgacctcca gctggaaggccccagcaccctcagggtcctggacgagaaccttgctgacccccaagcaga agacagacctctggttttctttgacctcaagattgacaatgaaagtgggttctcctgggg ctacccccacccctttctaatttagtctctgagtcccaaaaag

>38880_at HG-U95Av2 gcacccacgggtgtgctggatactggagtttgagaggagggaggtgctggggccaaagga gacactanaaaagtggtagatgggacaggtaagtggcagaggtgaggggntaagttanaa tgtanaagggcagtaattaggggtgagggaaaggagataggggaccctaggaggtagagt gggnccatgtcgtgaggcagttgaagagttgaggaaaggttttnctgggccctactgctc ccctctgctgcaggtaagtcagagcagctttaccacagcttcaggccacgagag

>38916_at HG-U95Av2 gaacctttcagtctccgctagctctttcctnnnnnnnnnnnnnnnnnnnnnngttttatc gttaagtgccccacagagacactttaccaggaggctgggagagttctccagatttgggag aggcgcagagacagtgtgtgagccgagccctgtctcagcaatccacctggaggagctaga g a cctcctccctttaccattcagaccgagagaaaaagcccagcttgtgtgcaccc cg tggggttaannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntttgttttgatgtaaggc tctgtggtttgggggggaacatctgtaaacattattagttgatttggggtttgtctttga tggtttctatctgcaattatcgtcatgtatatttaagtgtctgttatagaaaacccacac ccactgtcctgtaaacttttctcagtgtnnnnnnnnnnnnnnntcacattttaattgcca cctcg atttcacctctacatttgaaatctggcgtctgtttcaagccagtgtgtt

>38944_at HG-U95Av2 ctctcagaacatactgattgggaggtgcgtgttcagcagaacctgcacacaggacagcgg gaaaaatcga.tgagcgccacctctttaaaaactcacttacgtttgtcctttttcactttg aaaagttggaaggatctgctgaggcccagtgcatatgcaatgtatagtgtctattatcac attaatctcaaagagattcgaatgacggtaagtgttctcatgaagcaggaggcccttgtc gtgggatggcatttggtctcaggcagcaccacactgggtgcgtctccagtcatctgtaag agcttgctccagattctgatgcatacgg

>38970_s_at HG-U95Av2 accatccgttgcagaagcctccaggagcagcaatcctaagagtgggaggcagccnaagac ccccttccttcaaaanncntcccggaagtggtttcaggccctctagttgccatgaccaat ttgtgtgtgtgtttaatttttgcttcaagctctgtagcaggacctgccccacgcacaccc ctacccctctgtgaggagctgtgggaagtgtgggtttgtctccagaacagaagagaatga tggatattctggctctggggccctctccaccaccactcacagtagccttgctgaagccat cacagatgggagaaggccatgccagccacgtccgccgaggggcgccagcctgaagctgcc aggccctgaggttcagaccctggaccccatagctggaggcctgtggtgccagaagcccag attagggtggctgtccatccctggatagctatttgcacgaatcatggacataa

>38971_r_at HG-U95Av2 gcaatcctaagagtgggaggcagccnaagacccccttccttcaaaanncntcccggaagt ggtttcaggccctctagttgccatgaccaatttgtgtgtgtgtttaatttttgcttcaag ctctgtagcaggacctgccccacgcacacccctacccctctgtgaggagctgtgggaagt gtgggtttgtctccagaacagaagagaatgatggatattctggctctggggccctctcca ccaccactcacagtagccttgctga

>39032_at HG-U95Av2 atgacacaaaactatgagagtgacaaaatggtgannnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntgtagtgtaactattttg tancaatagaggactgtaactactatttaggttgtacagattgaaatttagttgtttcat tggctgtctgaggaggtgtggacttttatatatagatctacataaaaactgctacatgac aaaaaccacacctaaagaaattttaangannnnnnnnnnnnnnnnnntcactttngtngt aatctngaaatcntnnnnnnnnnnnnnnnnnnnnnnnnaatccttgttcactgaagtctt tcaattgagctggttgaatactttgaaaaatgctcagttctaactaatgaaatggatttc ccagtagggnnnnnnnnnnnnnnnntgtatagtagttatatgcatatgtttctgtgcatg ttctctacacaattgtaaggtgtcactgtatttaactgttgcacttg >39070_at HG-U95Av2 ggggccgtcttcctcctgtctctttcctttcaccctagcctgactggaagcagaaaatga ccaaatcagtattttttttaatgaaatattattgctggaggcgtcccaggcaagcctggc tgtagtagcgagtgatctggcggggggcgtctcagcaccctccccagggggtgcatctca gccccctctttccgtccttcccgtccagccccagccctgggcctgggctgccgaca^'cctg ggccagagcccctgctgtgattggtgctccctgggcctcccgggtggatgaagccaggcg tcgccccctccgggagccctggggtgagccgccggggcccccctgctgccagcctccccc gtccccaacatgcatctcactctgggtgtcttggtcttttattttttgtaagtgtcattt gtataactctaaacgcccatgatagtagcttcaaactggaaatagcgaa

>39071_at HG-U95Av2 actcagtgttttggagagtattccttttagtttgttggttggctggtttgaacgatagna aatatgcagcatgcaatatatgcttatatttcattttaatttctgatatataatgaactt cttgggagaggtactgaatctttgatgttttttgtcattgttctcaagtgcaatataaca atgtaaccaaatctagataatttcaaagttgtcattaatttagtaagcctaatataaaca aatatttgtattatttttnnnnnnnnnnnnnnnnnnttaagtgaggttatttacccctaa atggtccattctgcattgtatttcaggctggaaatgaattattctttaccagttttgaaa cactttgaaatatcctaaggtaacttggaagctgtgtagtatatcaaattaatttgctac ctaataacatagaaagtaaatatctttgtggtcacccacattgggtgagacagaaaat

>39081_at HG-U95Av2 gtgatccttatcagggagagcaggaatccttattcccggtgtcgctagtactcatctctg ccgcctcctgtctgcccccagnnnnnnnnnnnnnnnnnnncnncgaacccgcgnnnnanc ntgtcccgactctagccgcctnttcagcnnnncnnngnnnccnannnnnncnnnnncnnc ngnnnnnncnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaaatgcacctcctg caagaaaagc gctgctcctgctgccctgtgggctgtgccaagtgtgcccagggctgcat ctgcaaaggggcgtcggacaagnnnnnnnnnnnnnnnnnnnnnnnnnnnnnccccgctcc cagatgtaaagaacgcgacttccacaaacctggatttt

>39107_at HG-U95Av2 acttcagtgtcagtatccctgccttcagtcttctttagaaatcacatctgtgttcaatcc attgtttagagggagtg atttttcctgttccnnnnnnnnnnnnnnnngttcacaattgg atcacaatgcagaggagtctgttcctcccccgtcggcttctcggtgctgggagggtgacc tgtcccagatgactcatcaccctgacatgctcttgacaaaggacaccaccaagaggagat ggcagctgtaccggtgcagcctctgtctgagggggatatttgcctcagtgtgattaaaaa tcagtcatgaaagatttttgaattcagattatttt atcaggaacagattttgaacatcc tgaaatcttttccctggcatcatattaggttttctttgttcactatgatgtaaagtttca gactcttgatatttttaata caacatagacggtaggacaaggaacggtaccagaaatga gtaaagagacaataatgataagatcgatttatcaagacataacaaccccaaatgtatatg cactaaataacagcttcaaaatacatgaagcaaaatgg

>39119_s_at HG-U95Av2 gtcccggatgttgaggatcccgcaanccgaggagcctggggagagcttttntnacaaggt catgagannnnnnnnnnnnnnnnncntgcagcggctgcagacctggtggcacggggttct ggcctgggtgaaggagaaggtggtggccctggtccatgcagtgcaggccctctggaaaca gttccagagtttctgctgctctctgtcagagctcttcatgtcctctttccagtcctacgg agncccacggggggacaaggaggagctgacaccccagaagtgctctgaaccccaatcctc aaaatgaagatactgacaccacctttgc

>39120_at HG-U95Av2 tgtcccgctgcgtgttttcctcttgatcngggaactcctgcttctccttgcctcgaaatg gaccccaactgctcctgctcgcctgttggctcctnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnaaatgcacctcctgcaagaagagctgctgctcctgctgccctgtgggctgt gccaagtgtgcccagggctgcatctgcaaagggacgtcagacaagtgcagctgctgtgcc tgatgccaggacagctgtgctctcagatgtaaatagagcaacctatataaacctgga

>39253_s_at HG-U95Av2 aagcagacagctatcggaagaaggtagtgctagatggggaggaagtccagatcgatatct tagatacagctgggcaggaggactacgctgcaattagagacaactacttccgaagtgggg aggggttcctctgtgttttctctattacagaaatggaatcctttgcagctacagctgact tcagggagcagattttaagagtaaaagaagatgagaatgttccatttctactggttggta acaaatcagatttagaagataaaagacaggtttctgtagaagaggcaaaaaacagagctg agcagtggaatgttaactacgtggaaacatctgctaaaacacgagctaatgt

>39267_at HG-U95Av2 tgcacatgaagtgagcttggcagtatttcagctggctggaggaattggagaaaggcccca accaggtttctgaannnnnnnnnnnnnnnnnnnagaaactggactttttacaagtcttta caaaactgtcaataataatggcagtactaagagatttataatcataatgtttacaatgca gcctactggattgtctctagatctgtttttcttaaacactaacagaataattctt ataa ataggtaagccttacacttgttaaagaaatttacctctaatttcagtctcactaatgtaa aa ac gggacttaagtatacaattcagtcactaactgtacagttttatgtggggaacaa ttcatgcaggctac ggaaaattaaatcttattaccaannnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnncaagatgatgttttgcagcattcnnnnnnnnnnnnnnnaatggaga gggcagagaagacttta acaaccagtttttccattgcagagtcttaagaaagattatta gatgacttacctatatggactaatgccatccaggaactcagaggtatg

>39300_at HG-U95Av2 gaggcaggaatctccatttttgtgctttttgaaaatgcaatgaattcctatacgggggag cgggaaaggtgcctcagagagagacaagtctggatgagggaaatat gaatattctcaat caaannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngacttgaaagacctgag tccattacgttgagaagggacctgctgattgctttgattccccctggcaagtgctccctg gttgtgaatgccaggcactagagatggtgaggggttggggggcagttgggcacacacagt gtaagagcaattcagagccgttagtcctgcactagccctcaagctgctggcaacacctag agaaggtcgaagggccctgccagagatccc

>39310_at HG-U95Av2 gcaaagagcccataaatcctgaccaatccaactctgaattttaanncaaaagcgtnaaaa aaaagattccctccttacccccaacccactcttttttcccaccacccactctcctctgcc tcagtaagtatctggaggaagaaaacaggtgaaagaagaagtaaaaaccatttagtatta gtattagaatgaagtcaaactgtgccacacatggtgaatgnnaaaaaaaaaaaagaggct gtgttttgtcacacagggcagtcattcagcaccagagcacg gatggtctgagactctct taggagcagagnnnnnnnnnnnnnnnnnngtgggnnnnnnnnnnnnnnnnnnggggcaac tgagtctgcgggagaagagcggccctatgcatggtgta

>39327_at HG-U95Av2 ggttccatcacaagctatgtttaaaaagaaaattggtgtttggcaaacggaacagaacct ttgatgagagcgnttcacagggacactgtctgggggtgcagtgcaagcccccggcctctt ccctgggaacctctgaactcctccttcctctgggctctctgtaacatttcaccacacgtc agcatctaatcccaagacaaacattcccncntgctcgaagcagctgtatagcctgtgact ctccgtgtgtcagctccttccacacctgattagaacattcataagccacatttagaaaca gntttnntttcagctgtcacttgcacacatactgcctagttgtgaaccaaatgtgaaaaa acctccttcatcccattgtgta ctgatacctnccgagggccaagggtgtgtgttgacaa cgccgctcccagccggccctggttgcgtccacgtcctgaacaagagccgcttccggatgg ctcttcccaagggaggaggagctcaagtgtcgggaactgtctaacttcaggttgtgtgag tgcgt

>39333_at HG-U95Av2 gaatgacttgacttcaaaagcaacaaccttaaaggccgtcatttcattagtattcctcat tctgcatcctggcttgaaaaacagctctgttgaatcacagtatcagtattttcacacgta agcacattcgggccatttccgtggtttctcatgagctgtgttcacagacctcagcagggc atcgcatggaccgcaggagggcagattcggaccactaggcctgaaatgacatttcactaa aagtctccaaaacatttctaagannnnnnnnnnnnnnnatgtaatttctttaaatgtgta tttcttaagaattcaaatttgtaataaaactatttgtataaaaannaagcttttattaat ttgt gctagtattgccacagacgcattaaaagaaacttactgcacaagctgctaat

>39397_at HG-U95Av2 atttttaggtgaagtcgagcactctaattagagaactggaggaaccacatataacactta acttcccctaccctgcccctccccaaaagaaaccatgacaaacctagcttttaaaaaata ttttaagaaagagaatgaactnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnngtgaacttttgtaatttgaattgggtcccgcttagttc ttgaattgttatgaaaatcctatatctgtttgtatatttgcaaaccctttgtattataat tgttgatattttccctttttaaaaaataccattgaaatcagcatgacaaaaataacactg ttggcacttataggtaacgtga ■

>393_s_at HG-U95Av2 atacctgtttctttgggacattccgtcctgatgattttttattggttggtttttattttt ggggggaatgacatgtttgggtcttttatacatgaaaatttgtttgacaataatctcaca caacatattttacatctgagcacaatgcctttttgtttaccgtagcgtatacatttgttt tgggatttttgtgtgtttgttgggaattttgtttttagccaggtcagtattgat

>39402_at HG-U95Av2 aatgtggactcaatccctagggctggcagaaagggaacagaaaggtttttnagtacggct atagcctggactttcctgttgtctacaccaatgcccaactgcctgccttagggtagtgct aannnnnnnnnnnnnnnnncagccaggacagtcagctctctcctttcagggccaatcccc agcccttttgttgagccaggcctctctcacctctcctactcacttaaagcccgcctgaca gaaaccacggccacatttggttctaagaaacnnncctctgtcattcgctcccacattctg nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnaagggggcaagaagtagcagtgtctgtaaaagagcctagtttttaatagct atggaatcaattcaatttggactggtgtgctctctttaaatcaagtcctttaattaagac tgaaaatatataagctcagattatttaaatgggaatatttataaatgagcaaatatcata ctgttcaatg

>39409_at HG-U95Av2 ctggacacccatctctaaagcaggacgcctgccagggggatagtgggggcgtttttgcag taagggacccgaacactgatcgctgggtggccacgggcatcgtgtcctggggcatcgggt gcagcaggggctatggcttctacaccaaag gctcaactacgtggactggatcaagaaag agatggaggaggaggactgagcccagaattcactaggttcgaatccagagagcagtgtgg aaaaaaaaaaacaaaaaacaannnnnnnnnnnnnnnnnnnnnnnnagagtctctnnnaaa antnnnnnnnnanannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnttgatgtact ttacctgaaacaacccaaagggcccctttctttcttctgaggattgcagaggatatagtt atcaatctctagttgtcactttcctcttccactttgataccattgggtcattgaatataa c

>39421_at HG-U95Av2 gacggtataacacatctactgaaaaagcaannnnnnnnnnnnnnnnatttaagccagccc ccacctagggtctatttgtgtggcagttattgggtttggtcacaaaacatcctgaaaatt cgtgcgtgggcttctttctccctggtacaaacgtatggaatgcttcttaaaggggaactg tcaagctggtgtcttcagccagatgacatgagagaatatcccagaaccctctctccaagg . tgtttctagatagcacaggagannnnnnnnnnnnnnntccacagtccacggtacacagtc gggtgggccgcctcccctctcctgggagcattcgtcgtgcccagcctgagcagggcagct ggactgctgctgttcaggagccaccagagccttcctctctttgtaccacag

>39517_at HG-U95Av2 tcttaggggtcattatcacttaaataatactgtacctaggtctttcaaattaaaattata cctgaatgaagttgtttgtatacataaaggatatttgtgtacaattaccttttttccccc acacttgttttctttgtttttgttnnnnnnnnnnnnnnnnnnnnnnntnnactatgggat tcatttatgtctgtctttctatcataaagaattgatcaatatgtaaatatgtgatttgaa ccatggttgacttacaagtgtcactacagctttttagaaaacatagccctaatatatgtt aagcaggacccgggtgagccagtggnnttgcgctttatgtagagctggaagaaggccgtc catcctgtctcttgggcggacagtgtactttcctaatagggaagggaagcacaatggaaa tacccctgaaccg

>39532_at HG-U95Av2 attgccaccctgaaccagctctgtgccaccaagttccgagnnnnnnnnnnnnnnnnnnnn nncctcttcctgtacaaggagnnnggctaccnccgcctgccccctgggnccntggccnac aggctgcccaccactggctacctcgtctaccgccgggcagagtggcctgagacccagggg gctgtgacagaggaggagggcagtgggcagtcagaggcaagaagcagaggggaggagcaa gggtgccagggagatggggatgctggggtcaaagccagccccagggacattcgggaacag tctgagacaactgctgaagggggccagggtcaagcccaggaaggccctgctcagccaggg gaaccagaggcagagggaagccgggcagcagaggagnnnnnnnnnnnnnnnagaagggtc attcggggcgggagaccctgagcctgctgagaaatccttttagcgccagcaagccccacc cagggccctgtcctgtgtctgccaccacctttgtctgatacttgtttccagggaagctgg gggaactgccacatctgaggaactggaataa

>39579_at HG-U95Av2 attcatactgtcagggctgtgctcaatgactggatgttccctatatgcaaacaaaatcac aacggaattctttgatcctctctttgttgagcaaaagtatgaattaggagccgctctgtt tattggatgggcaggagcctcactgtgcataattggtggtgtcatattttgcttttcaat atctgacaacaacaaaacacccagatacacatacaacggggccacatctgtcatgtcttc tcggacaaagtatcatggtggagaagattttaaaacaacaaacccnnnnnnnnnnnnnnn naaaaatgcttatgtctaaaagagctcgctggcaagctgcctcttgagtttgttataaaa gcgaactgttcacaaaatgatcccatcaaggccctcccataattaacactcaaaactatt tttaaaatatgcatttgaagcatctgttgattgtatggatgtaagtgttcttacatagtt agttatatactaatcattttctgttgtggct

>39633_at HG-U95Av2 gacaaatacaagctctgccaggcggngntnnnnnnnnnnnnnnngaaggagctggccacn tggaccccgactgagtttcgggaatgtgactacaacaaattcatgagtgttctggacacc aacaaggactgcgaggtggactttgtggagtatgtgcgctcacttgcctgcctctgtctc tactgccacgagtacttcaanggactgcccctncagagcccccctgctnccnagtagcct ctgctccagggggtgcgctggctgtcgggggnctgggcatgtctcccacaccccctcct ccctctctcctgtacccctttcaatctggacttgcccaggtcttctgcgatcagttaacc cattttacctaggaggcccagagatgtgagggctccttcctcaggatgcccagcgaatga ggggtagagccactctgggncccagcctgcctgccgcacccctgtggcctcccttgtgga tgggaggaggcgggatctgctctgaggccctcgaggctcagcagagcgtgcaccaatgag accacgatgggaaagg

>39640_at HG-U95Av2 atacagctctcttcagagtaactgtnaaccttttataaccaacactagagttnnntttnn aaaagacaagatatttataatgacgactngtatagcttttaagttatttttctagtatgt ggctttctntagccgtgntaacgnncaaactgttcatcnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnagcacaaggcattggccctct ggactcctttctccttttctttcctctctaggctgctcctgaatcctgttctctgacatc cgtggagcccctcctgcatccacctatgcctcctataagtccanttgaaatctcagcctc cttcaacattttcttctcgtgtgtggcccacatccctccacttctccaacttctgtttaa tctgatcacggctctttttaagccctggcagcattttggtccctgctccttgcccatagt aaannnnnnnnnnnnnnnnnnnnnnnnnnnnnagtttcaagtgggcaactctgctc cta tt

>39663_at HG-U95Av2 ggtcagttatccttctctccttagccacataacttcttctctcatgaatcatccagtcat tccaatggcaaataagttctcctcacctacccttgagctgcaaggtgaattcnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaggt gggcaatgggcactccaatgaggcagccttgatcctccacagaaaagggtttgattg cg gttctctagcaaaggcacagggctgttttgttctactactcagggaaagatattggtaca gaaacttttaaacaagtttattgtcgaaagtctcacaccttcatcactatccttgatgca ttcacctcccggcactcagaatataagtgagatcaacttgagtccaatggaaatcagcac attccgaatccagttgaggtgaacctgactttcacatttggattgagaatcattggcttt tatacctttcttggtttgacgtgcaataaagaagcacattattttagcttctggc actg tgag

>39680_at HG-U95Av2 gtctcatcttgagtaaaagagaacccagccaactatgaagttccttgtctttgccttcat cttggctctcatggtttccatgattggagctgattcatctgaagagaaatttttgcgtag aattggaagattcggttatgggtatggcccnnnnnnnnnnnnnnnagaacaaccactata cccacaaccataccaaccacaataccaacaatataccttttaatatcatcagtaactgca ggacatgattattgaggcttgattggcaaatacgacttctacatccatattctcatcttt cataccatatcacactactaccactttttgnangaatcatcaaagagcaatgcaaatgna aaacactataatttactgtatactctttgtttcaggatacttgcc

>39681_at HG-U95Av2 tgcagcagcacatggaggtccacgcgggcgtgcgcagctacatctgcagtgagtgcaacc gcnccttccccagccacacggctctcaaacgccacctgcgctcacatacaggcgaccacc cctannnnnnnnnnnnnnnnggcagctgcttccgggnnnnnnnnnnnnnnnagagccaca aacgcatccacacgggtgagaaaccctacgagtgcaatggctgtggcaagaagttcagcc tcaagcatcagctggagacgcactatagggtgcacacaggtgagaagccctttgagtgta agctctgccaccagcgctcccgggactactcggccatgatcaagcacctgagaacgcaca acggcgcctcgccctaccagtgcaccatctgcacagagtactgccccagcctctcctcca tgcagaagcacatgaagggccacaagcccgaggagatcccgcccgactggaggatagaga agacgtacctctacctgtgctatgtgtgaag

>39728_at HG-U95Av2 tgtgccctgggtcaccgtcaatgggaaacccttggaagatcagacccagctccttaccct tgtctgccagttgtaccagggcaagaagccggatgtctgcccttcctcaaccagctccct caggagtgtttgcttcaagtgatggccggtgagctgcggagagctcatggaaggcgagtg ggaacccggctgcctgcctttttttctgatccagaccctcggcacctgctacttaccaac tggaaaattttatgcatcccatgaagcccagatacacaaaattccaccccatgatcaaga atcctgctccactaagaatggtgctaaagta

>39742_at HG-U95Av2 ggaaaatctagtttcacagctatttgaatttttttctggatttactatataactcttatt ttttaaaagatcattctgttctttcaaggagaaataagcctaaaagaagaaaaacaaaaa aaattctgtataaaactgtaatncctttgtattcatgtttacagtgctattactataatt caaaattatgtatgtgacttagagttatataatca aatttatgtttatttcaaatatct aagtttattgcttggatttctagtgagagctgttgaatttggtgatgtcaaatgtttcta gggtttttttagtttgtttttattgaaaaatttaattattta gctat ggtgatattct ctttgaataaacctataatagaaaatagcagacaacataaacatctttgtaaatatcaaa cctaatacatttcttgtccagtgataaaacaactgg

>39781_at HG-U95Av2 actcccctgggcatcttctggcttgactggatggaaggagacttaggaacctaccagttg gccatgatgtcttttcttctttttcttttttttaacaaaacagaacaaaaccaaaaaatg tccanaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaanaaaaaaanaannnnnnnnnnatc cagtcaagccatgatgtcttttcttct

>39791_at HG-U95Av2 gtaacagacattgttttgccaacattgcctatttcagtggcacgtcatctagttttaaaa aaataaaacattttaaatggacaganaaaaaaaanannnnnnnntttaactcgtaagtgn nnnnnnnnnnnnnnnnngacatgtccnnctttctctccagttcnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnagttgtactctgcttgaggggaagaaggctcctgctctgctgtgta ggtagtcataggaattgtattcttaatgtacaggcactaattg catctgtga gtacat

111atgnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntatgtgtgtg tatgtgtgtgttttgtaaaatctgtaaatagcacatgaccaaatgaacatattg

>39805_at HG-U95Av2 aggcatccatgatgccattatggctttccctgaagggtacaggacacannnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnntcnaatganag ggccatccaggcttctctggccaaagtctgtgccaaccgcnnccaccntngtagtggcac acaggctctcaactgtggtcaatgctgaccagatcctcgtcatcaaggatggctgcatcg tggagaggggacgacacgaggctctgttgtcccgaggtggggtgtatgctgacatgtggc agctgcagcagggacaggaagaaacctctgaagacactaagcctcagaccatggaacggt gacaaaagtttg

>39826_f_at HG-U95Av2 cttaaacgcagctgccaggtgtaatttttcaagtgtcaaagatcccaagtgatccctgac acccaccccttcctactcttacattcatgcgtctnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnntgctccgatcagaanaannanannnaaaanaacnnncanncacannnggnccn tnnanancagnaananacacaanccacctccacgacctccgacctcccccctccctccgg ntngctctgaggnagcacgtgcctcttccttcaccctgggccnggctggggcgggagcag ccnagctgctctctggatgtcacaccactgttaactgtca

>39878_at HG-U95Av2 atggatgtcaatgacaccagcccagttgtcatttctccaccgtctaatacttcctttaag ttggtgcccctctcagccattcctgnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnctggaatgaacgctgaactaaagnnnnctatagtnagtgnaancnntaannncnna tnnnnnnnngnnnnnnnnacaggtaacattactnnnnaanaaaaaccancncctactgat gtgggattgcatcgtttggtggtcaacataagtgancctggggtanccctaagtctttgc acacgcttgtgcttgtattcctttatgttnnnnnnnnnnnnnnnnnngcctcctatatct atgacttgatccgcaggactatggagaccccgttggacaggaacataggggatagtagcc aaccctatcaaaatgaggac atctaaccatcatgattgccatcatcgccggtnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnggtnnnntgtcgccatgcatcaaggttca aagcagctcagaggagcaagcaaggtgccgaatggatgtcccc

>39959_at HG-U95Av2 cttatggcattgacaaagagaagaccatccaccttaccctgaaagtggtgaagcccagtg atgaggagctgcccttgtttcttgtggagtcaggtgatgaggcaaagaggcacctcctcc aggtgcgaaggtccagctcagtggcacaagtgaaagcaatgatcgagactaagacgggta taatccctgagacccagattgtgacttgcaatggaaagagactggaagatgggaagatga tggcagattacggcatcagaaagggcaa

>39966_at HG-U95Av2 caggctgacttggatgtgaactgtcttcagaataatttaacctaaagcagagcaagaaga gaggaagcgggggtagtgggtggggggtaggggaagaannattatctcctcttgtacaga gtctatttcttgtaaccatttgttaaactcttttctttttctgatctcatggcatgcttt tatgtattttgtacaggaggcaaaaaaaatacttaaaataagcaaagaaactgaacagaa ttgcatacattgggttgttttttctgtgctgtctgtacattgcttctgc gctgtgattt ctaaacctgtgctgttattcaactgactttt

>40049_at HG-U95Av2 cctccagggtgattttatgatcagtgttgttgctctaggaagacatttttccgtttgctt ttgttccaatgtcaatgtgaacgtccacatgaaacctacacactgtcatgcttcatcatt ccctctcatctcaggtagaanggttgacacagttgtagggttacagagacctatgtaaga attcagaagacccctgactcatcatttgtggcagtncccttataattggtgcannnnnnn nnnnnnnnnnnnnttagatcctggtttcataacttcctgtacttgaagtctaaaagcaga aaataaaggaagcaagttttcttccatgattttaaattgtgatcgagttttaaattgata ggagggaacatgtcctaattcttctgt

>40051_at HG-U95Av2 tcattgtccaggaataagattggcgtggtgcccatgacatcaccgtcactctgcctaaaa gcactctagagctacttgttcacgtggagaggaaggatattttgcgaancaacagnccgc aggtggagagccctgttcacctgatagggtctagctgtgacagtaaatataataccgctg tttccttgggtacagatttgagtgttcatgtgatgagactgtaaacctcatttttcggtt cctctgtttaaaaaaacatctgaaggatgaactaaggctgctggtgccctgagcaactga taatgcaaatgtggacaaagtgtctgttttctactctagcctgttcatatggaccaaatt tcaacaaggaactcaaggaaaatttgtacctgccgtatttatgctttcatgtaaaa

>40069_at HG-U95Av2 ctgccttcttgttccagctaggcaatgcntttttttttttttttgaagcagttctcttta taaagtgttattttgatagtttgtggattctaaaatatatatatat tatataaacacca tataagtcaaatatgtatttaacaaagcaatatgtattcattcactttcaagatttgttt tggtgtcaaaataacatgaaaaggtagatggagttgcttctgttgaattagctctgccac caatatgtatcttcatacacgtttggaaatgtttcctgcagcattaggtatgacttgttc tgagtactgcttccggtgctaaaatgaacaaagaatttgtacttaatggcatggactctg gagaatctatgcgaatcaacctttctaccttaatatctccccaaaaatgtatagtgcctt gtttttatgtacagtttnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnatgatggtttnnn nnnnnnnnnnnnnttttactctcaaatagtcaaaataaaaacatctcaatttctaatanc ngttgtaaacannnngtacacatgtcattttgtgatataggactcccaaataaa

>40088_at HG-U95Av2 atgtatacagttgcaagtctggacaaatgtatagaataaaccttttatttaagttgtnnn nnnnnnnnnnnnnnnaanngnnnnngggnnncnntgnnnnnnnnnnnnnnnnnnnnnnnn tnnnnacaaatcagatcagatgttca cctnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnttgattcgaagggtcttaaagaattt ttttaatcgtcaaccacttttaaacataaagaattcacacaactactttcatgaattttt taatcccattgcaaacattattccaagagtatcccagtattagcaatactggaatatagg cacattaccattcatagtaagaattctggtgtttacacaaccaaatttgatgcgatctgc tcagtaatataatttgccatttttattagaaatttaatttcttcatgtgatgtcatgaaa ctgtacatactgcagtgtgaatttttttgttttgttttttaatcttttagtgtttacttc ctgcagtgaatttg

>40091_at HG-U95Av2 aaaggctcgattttgtatctgcaggcagacacggatctgagaatctttattgagaaagag cacttaagagaatattttaagtattgcatctgtataagtaagaaaatattttgtctaaaa tgcctcagtgtatttgtatttttttgcaagtgaaggtttacaatttacaaagtgtgtatt aaaaaaaacaaaaagaacaaaaaaatctgcagaaggaaaaatgtgtaattttgttctagt tttcagtttgtatatacccgtacaacgtgtcctcnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnngcgagcgtgcaccatccctttttgaagtgtaggcagacacagggacttgaa gttgtt ctaactaaactctctttgggaatgtttgtctcatcc

>40126_at HG-U95Av2 ttaattagggatcttgctgcttttctttttctacacgaagttttcattaaagccacagan nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnttaaatgaa ttagaaactatttgaggc a aaaaatgtccttgagtttggagcctgagctctggnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnagagtaagnnnnnnnnnnnn nnnnnn atccgttcttcacttagcaggaatatgaaagaaaggcacatgtttaagaggaa tacctaaaggtttttctaaattccaacatttaaaaggcaattgtgggctatttttatttt ttaatattttgaaataaagtttagtgtctagggctgggagccaggactgatcttccattt ctt

>40153_at HG-U95Av2 ggtactcccgctcagtgcttctca cacccagcacctcagcctggtggagcaggctgacc acatcctctttctggaaggaggcgctatccgggaggggggaacccaccagcagctcatgg agaaaaaggggtgctactgggccatggtgcaggctcctgcagatgctccagaatgaaagc cttctcagacctgcgcactccatctccctcccttttcttctctctgtggtggagaaccac agctgcagagtaggcagctgcctccaggatgagttacttgaaatttgccttgagtgtgtt acctcctttccaagctcctcgtgataatgcagacttcctggagtacaaacacaggatttg taattccttactgtaacggagtttagagccagggctgatgctttggtgtggccagcactc tgaaactgagaaatgttcagaatgtacggaaagatgatcagctattttcaacataactga agg

>40171_at HG-U95Av2 aatgtatgcgccagggtgcttccgtggggcannnnnnnnnnnnnnnccatccaagcccaa ggacctgggataaactgggagaactatggcagctacttgcatcgacttgtacctcactta gcccttggg

>40177_at HG-U95Av2 atattatactttagggcaaccctagttggcagctttgagagaagt cttcattacagaag aattccattaaacatggaaggaataactaaactaaaaatca cactttgcaattctgaat gaaatnnnnnnnnnnnnnnnnnatttattattggataaaaccatcaga ataaggttaat agggaacttgacagcagacagagggaagag

>40199_at HG-U95Av2 gtttcacctctttgctccctgagttcactctccgaagtctgatccctgccaaaaagtggc tggaagagtcccttagtactcttctagcatttagatctacactctcgagnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaagaa aagcgcagagaaatcggtgtctgacgattttggaaatgagaacaatctcaaaaaaaaaaa aaaaaaaaaaaaaaaaannnnnnngaaaagagaaaaaaaagactagccagccaggaagat gaatcctagcttcttccattggaaaatttaagacaagttcaacaacaaaacatttgctct ggggggcagggaaaacacagatgtgttgcaaaggtaggttgaagggacctctctcttacc

>40214_at HG-U95Av2 gctacgtaaggcagcccgtgaaccaagcctactttttctgtcatntgattcaccatgtca gtaagcgtatctggaattactcttattccactatcacaaatccatataagatca acttt gcaacttcatatcctggcattaaattattaattttaggattaatgccaacttttttgcca cctataaacaatctagcatcaacatttggatattttccannnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnntcatgatcttgtacacaaaggagcacttcatatttgggataatccaat tcaaagaatgtttccaggttgttgattaagttaggatctacccctttcagtggtttcaga agagagacacctgggagcttgctataaggctgtttgtcagttgccttcttgttgaggt

>40215_at HG-U95Av2 caatgtccactcaagttgcaatgcaaaactctggctcatattcaatttctcagtttcaat ccagaatgatcaggtggaccaaactacgaattaacatgcttcctgctacaataatttgtg agccaatttcagaatgctttgttgccagtttaattattggatgggcagcccaccatgtgt tcagatgggatattatggtatttttcatgtgtcattgcctggcatggtttatatttgact acattcaactcaggggtgtccagggtggcacactgtgtttttcaaaacttgattatgcag tcgcctggttcatccgcgaatccatgacaatatacatttttttgtctgcattatgggacc caactataagctggagaactggtcgctacagattacgctgtgggggtacagcagaggaaa tnnnnnnnnnnnnnnnnnnnnnnnntgactgtatataaaggaaaaaagagaagtattata aattatgtttatataaatgcttttaaaaatctaccttctgtagttttatcacatgtatg

>40236_at HG-U95Av2 ctttcctcgtgttgggcctgagtgtcttgaccacttacggagttcatgccatcnncaggc tggaggcctggagcctcgctctcctcgcgctgtttcttgttctcttcgttgccatcgttc tcaccatctggaggcagccccagaatcaacgaaaagtagccttcatggttccattct

>40240_at HG-U95Av2 tctcgctgcctcacaagcagtgacacctcgggtcctttccgttgctatggtgaaaat cc tggatggaatggatcacatgagggtttcttgttgcttttggagggtgtgggggatatttt gttttggtttttctgcaggttccatgaaaacagcccttttccaagcccattgtttctgtc atggtttccatctgtcctgagcaag cattcctttgttatttagcatttcgannnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnacctctagcatcgann nnnnnnnnnnnnntnanctgacggcatggaatgtataaatgagggtgggtccttctgcag atactctaatcactacattgctttttctataaaactacccataagcctttaacctttaaa gaaaaatgaaaaaggttagtgtttgggggccgggggaggactgaccgcttcataagccag tacg

>40290_f_at HG-U95Av2 agacaggacagtttcccaggaagatgggcagagacttgagtgngcnnnnnncnnnnncac agagacgtgccangcggtgttggcgctcggggcgagatgctgcccttctttngcacgann cntggcctcttgcttggcgtgataaccctgtcatcttcccaaagctcatttatgagccac cagaggctcct

>40310_at HG-U95Av2 tttccgtctttttgatgagaacaatnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaagacct acctggagtggcccatggacgaggctcagcgggaaggattttgggtaaatctgagagctg cgataaagtcctaggttcccatatttaagaccagtctttgtctagttgggatcttnnnnn nnnnnnnnnnnnnnnnnnnnattcagacataattatataaaaactacgtggatgtaccgt catttgaggact gcttactaaaactacaaaacttcaaattttgtctggggtgctgtttt ataaacat tgccagatttaaaaattggtttttggtttttcttttttctatgagataacc atgatcataagtct

>40314_at HG-U95Av2 ctgtgggccaagacaccagccctgtcctagcccttcagtaannnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnngnnaagacaagcccctcagcaggagagaggcccagaggctc cagctggccaccgtgccccacaagatggcccctgtgtggttccctttaccttggcttcct ggcccagtccctgcctctccacctgcaccctgcttcctnggcccagtcccaggttggagt ccctctgcatagctgactactcatgcattgcnnnnnnnnnnnnnnnnnnnnnnnnnnnnc aacaccaaacgtggttgccacatttcatcagacagacacctccctctggagatgcagttg agtgacaaccttgttacattgtagcctagaccaattctgtgtggatatttaagtgaacat gtttacaatttttgtatatatcactctctccctctcctgaaagaccagagattgtgtatt ttcagtgtcccatgttccgactgc

>40322 at HG-U95Av2 ttgctgtctgatctttgtagactgttcctgtttgctgggagcttctctgctgcttaaatt gttcgtcctcccccactccctcctatcgttggtttgtctagaacactcagctgcttcttt ggtcatccttgttttctaactttatgaactccctctgtgtcactgtatgtga

>40333_at HG-U95Av2 agcatcactcacagcgggccaggaagaagaanaagnactgccggcgcnactcgctctatg tggactnnnnnnnnnnnnnnnnnnnnnnnnctnggattntnggccccaccaggctaccag gccttctactgccatggggactgcccctttccactggctgaccacctcaactcaaccaac catgccattgtgcagaccctggtcaattctgtcaattccagtatccccaaagcctgttgt nnnnnnnnnnnnnnnnnnnncatctccatgctgtacctggatgagt tgataaggtggta ctgaaaaat atcaggagatggtagtagagggatgtgggtgccgctgagatcaggcagtc cttgaggatagacagatatacacaccacacacacacaccacatacaccacacacacacgt tcccatccactcacccacacactacacagactgcttccttatagctggacttttatttna aaaaaaaaaaaaaaaanggaaaaaatccctaaacattcaccttgaccttattta gactt tacgtgc

>40362_at HG-U95Av2 tgtcacttggtgatacagctctgcagaacctggagcagctgctagacgggccagaagccc agggcagctgggcagagctggcagagcgtctggggctgcgcagcctggtagacacgt cc gacagacaacctcacccagtggcagcctcctgcgcagctacgagctggctggcggggacc tggcaggtctactggaggccctgtctgacatgggcctagaggagggagtgaggctgctga ggggtccagaaacccgagacaagctgcccagcacagaggtgaaggaagacagtgcgtacg ggagccagtcagtggagcaggaggcagagaagctgggcccaccccctgagccaccaggag ggctctcgcacgggcacccccagcctcaggtgactgacctgctgcctgcccccagccccc ttcccggaccccctgtacagcgtccccacctatttcaaatcttatttaacaccccacacc cacccctcagttgggacaaataaaggat

>40367_at HG-U95Av2 gtgtctccaagagacatgttaggataagcaggtctttgcaccaagatgaacacagctggt cacagataaggccat gctagtaacttttggccatgatggaaaagggcatcctctccaca aaagagaaaaacgtcaagccaaacacaaacagcggnaacngnnttaagtccagctgtaag agacaccctttgtacgtggacttcagtgacgtggggtggaatgactggattgtggctccc ccggggtatcacgccttttactgccacggagaatgcccttttcctctggctgatcatctg aactccactaatcatgccattgttcagacgttggtcaactctgttaactctaagattcct aaggcatgctgtgtcccgacagnnnnnnnnnnnnnnnnnnnnnnntaccttgacgagaat gaaaaggttgtat aaagaactatcaggacatggttgtggagggttgtgggtgtcgctag tacagcaaaattaa

>40370_f_at HG-U95Av2 atcatac gacctggcagcgggatggggaggaccagacccaggacgtggagctcgtggag accaggcctgcaggggatggaaccttccagaagtgggcagctgtggtggtgccttctgga gaggagcagagatacacgtgccatgtgcagcatgaggggctgccggagcccctcatgctg agatggaagcagtcttccctgcccaccatccccatcatgggtatcgttgctggcctggtt gtccttgcagctgtagtcactggagctgcggtcgctgctgtgctgtggagnaagaagagc tcagattgaaaaggagggagcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnngtggcaagtccctttgtgacttcaagaaccctgacttctctttctgcagagacc agcccacccctgtgcccaccatgaccctcttcctcatgctgaactgcattccttccccaa tcacctttcctgttccagaaaaggggctgggatgtctccgtctctgtctcaaa

>40385_at HG-U95Av2 aggctgtgacatcaatgctatcatctttcacacaaagaaaaagttgtctgtgtgcgcaaa tccaaaacagacttgggtgaaatatattgtgcgtctcctcagtaaaaaagtcaagaacat gtaaaaactgtggcttttctggaatggaattggacatagcccaagaacagaaagaacctt gctggggttggaggtttcacttgcacatcatggagggtttagtgcttatctaatttgtgc ctcactggacttgtccaattaatgaagttgattcatattgcatcatagtttgctttgttt aagcatcacattaaagttaaactgtattttatgttatttatagctgtaggttttctgtgt ttagctatttaatactaattttccataagctattttggtttagtgcaaagtataaaatta tatttgggggggaataagattatatggactttcttgcaagcaacaagctattttttaaaa aaaactatttaacattcttttgtttatattgttttgtctcctaaattgttgtaattgc

>40391 at HG-U95Av2 tactttgtttacctcggtgcttacaacagaatgctgccctacatcgtcatgggtagtctg actgtcctgattggaatcctcaccctttttttccctgaaagtttgggaatgactctnnnn nnnnnnnnnnnnnagatgcagaaagtgaaatggttnannnnnnnnnannnnnnaaaaaaa caagagactcaatgnagnnannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnntgaaaaacagaaaaataagaccctgtggagaaattcgt tgttcccactgaaatggactgactgtaacgattgacaccaaaatgaaccttgctatcaag aaatgctcgtcatacagtaaactctggatgattcttccagat

>40393_at HG-ϋ95Av2 gtgtggatacctgagaaggac c tggtatcaaatacttttgagatggctacagtcagc tagctggacagcccatgctgactggggacatacacttgcatctttgttgaaagcagaaga agacagaccctttccccaccttccttacctcctcttcccccattaaggcagctcatccaa gcttgtatttaactgaataaatgagtagacattgtggacctcacaagattattt

>40398_s_at HG-U95Av2 atttcttcctgattgacaacagtgttagacaaggtgcaaagcgaaactggt gctcaagt tgatagaaaac

>40399_r_at HG-U95Av2 acaatcagtatgtgcttacctgtgttcaagtagagaaaaatacagtagagtctgatagga catattcttgtaccacagacaaaacaaatcttatgttgcatttactatcaactgctgcta atacgttattataaaacttacctagctcctgaattcttcctatctta agcttaaa

>40427_at HG-U95Av2 catagctgcttttggcgcgaaagatgccgggtctggttgactcaaaccctgccccgcctg agtctcaggagannnnnnnnnnnnnnnnnnnnnnnnnttgcccggagaccaagaaggcgc ncgatgcgtgtatcatcgagaaaggagaagaacactgtggacatctaattgaggcccaca aggaatgcatgagagccct

>40434_at HG-U95Av2 agaattgctactcgaaggtgccagaatgacacaaaggacagaattcctttcccagttgtt accctagcaaggctagggagggcatgaacacaaacatannnannnnnnnnnnnnctacac tntctntnaatnanttnngnnnnnnangtnannnaannnttnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnggaacttactccaacaggactgagggaccaagg aaacatgatgggggaggcagagagggcaagagtaaaactgtagcatagcttttgtcacgg tcactagctgatccctcaggtctgctgcaaacacagcatggaggacacagatgactcttt ggtgttggtctttttgtctgcagtgaatgttcaacagtttgcccaggaactgggggatca tatatgtcttagtggacaggggtctgaagtacact

>40493_at HG-U95Av2 agagaccctgagttcccactcagacccactcagccaaanntctcatggaagaccnaggan gggcagcactgnntttttgnnttttttgtttttngttttttttttttnngnacactgtcc aaaggttttccatcctgtcctggaatcagagttggaagctgaggagcttcagcctctttt atggtttaatggccacctgttctctcctgtgaaaggctttgcaaagtcacattaagtttg catgacctgttatccctggggccctatttcatagaggctggccctattagtgatttccaa aaacaatatggaagtgccttttgatgtcttacaataagaataacatggtccattcacctt tatgttatagatatgtctttgtgtaaatcatttgttttgagttttcaaagaatagcccat tgttcattcttgtg

>40496_at HG-U95Av2 tacaggatcccaatgacaagaccaanttctacgcagctggcctggtgtcctgggggcccc agtgtgggacctatgggctctacacacgggtaaagaactatgttgactggataatgaaga c atgcaggaaaatagcaccccccgtgaggactaatccagatacatcccaccagcctctc caagggtggtgaccaatgcattaccttctgttccttatgatattctcattatttcatcat gactgaaagaagacacgagcgaatgatttaaatagaacttgattgttgagacgccttgct agaggtagagtttgatcatagaattgtgctggtcatacatttgtggtctgactccttggg gtcctttccccggagtacctattgtagataacactatgggtggggcactcctttcttgca ctattccacagggataccttaattctttgtttcctctttacctgttcaaaattccattta cttgatcattctcagtatccactgtctatgtacaataaagg

>40505 at HG-U95Av2 tccccctagggctcaggcactgaggngcctggggacagtggagcatatgggtgggagaca gatggagggtaccctatttacaactgagtcagccaagccactgatgggaatatacagatt taggtgctaaaccntttattttccacggatgagtcacaatctgaagaatcaaacttccat cctgaaaatctatatgtttcaaaaccacttgccatcctgttagattgccagttcctgggn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnannnnnnaaaaaaaaaaaaaann nnnnnnnnannnannannanattgagggcctccaggacttggcaagtcttggtnnnnnnn nnnnnnnnnnnnnnnnnnnngatgggcaggcaaatctgtccgttctc

>40511_at HG-U95Av2 ccgttcaccagttgccattgagggtttcagagagcctttttctaggcctacatgctttgt gaacaagtccctgtaattgttgtttgtatgtataattcaaagcaccaaaataagaaaaga tgtagatttatttcatcatattatacagaccgaactgttgtataaatttatttactgcta gtcttaagaactgctttctttcgtttgtttgtttcaatattttccttctctctcaatttt tggttgaataaactagattacnattcagttggcctaaggtggttgtgctcggagggtttc ttgtttcttttccattttgtttttggatgatatttattaaatagcttctaagagtccggc ggcatctgtcttgtccctattcctgcagcctgtgctgagggtagcagtgtatgagctnnn nnnnnnnnnnnnnnnnnnnnnnnnncgacaggccacgtcctgcaatcggcccggctgcct cttcgccctgtcgtgttctgt

>40568__at HG-U95Av2 cacatgattacaattgccagtagagttgttgtttggggtacaagatgagaagaaagaaaa acctacagcctttctacattctgacatgctaacagtggtttaagtttctaaagtgttnnn nnnnnnnnnnnngncaaggggagggagcagaagcacttatgtttacggatattttaaact ctgttagagagcagcctttgaaaatccccaatttggttctgctttttgacctctctctac cttttcagggtaatctttgtggnnnnnnnnnnnnnnnnnnnnangctttnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnngnccctgagcgatcttctatgcagttctgccatgcg tcctgttggtctctctgtgttctttgttacttgggtgcaatagcaacttccctaccccgt gcattccatctttcatgttgtgtaaagttcttca

>40604_at HG-U95Av2 atggtttgacttattcttcgtatcattagaagaaccccagagatagcattcctctatttt attttactttcttttggattgcactgattgtttttgtgggaatgacactttatctggcaa agtaactgagagtttggtaaaagaatattttcttctctgaataataattattttcacagt gaaaatttcagtattttatcactaatgtatnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnctgcctgtttggaca ataggttttgggtagtacagattaggataagtaagcttatatatgcacagagattattgt attacctgtaaattgatttacaagtacttaaaagcgtggtccccagtgaggccaaga

>40606_at HG-U95Av2 tcgtctcctatgagcaacgccagaattataaggatgacttcaatgcagagtatgatgagt acagagctttgcatgccaggatggagactgtagctagaagatttatcaaactagatgcac aaagaaannnnnnnnnnnnnnnntcaaaagagtatcagaatgttcatgaagaagtcttac aagaatatcagaagataaagcagtctagtcccaattaccatgaagaaaaatacagatgtg aatatcttcataacaagctggctcacatcaaaaggctaataggtgaatttgaccaacagc aagcagagtcatggtcctagaactctgcttggaccagaagatgtgaataaacttaagctt atttatttaaaattcnnaannannnnnnnnanantctaaaaaggtgaaactttggctgtt gaaagtttcagtattagtaaacttngagttactttttcttttccattttactttgcttcc ctgcatttcggaag

>40626_at HG-U95Av2 ctgtgttccctcttggaacctgaccnnnnatgctagaagaacccttggaaaacatgctgg cccagccctctagttttacaaataagggagtgcacagccctgagaggttacatggcctgc ccaagatcacgcagtcaatggcagagtaaagagcatagcctaggcctccccactcctcta gtaatgctctttcatcttctccaacctggctctaagccttgtccatcctgagccccatat ctagcccaacctagtccctgaaaacaagaagtggcccttagaaatctctctccagtccca ctatcagaggccaactgctgtcttccagtctccttcagcctgtgctcctctccctccctg actgacaggcagaaggtacngtgcctctggatatccccacagtgccctgagctgcatctc ttgcngactgctttaatacatcacagtgacattgtgtgtgtctctgccac

>40648 at HG-U95Av2 atccaattgtacctgatgtttttggtatttgtcttccttaccaagtgaactccatggccc caaagcaccagatgaatgttgttaagtaagctgtcattaaaaatacataatatatattta tttaaagagaaaaaatatgtgtatatcatggaaaaagacaaggatattttaataaaacat tacttatttcatttcactta cttgcatatcttaaaattaagcttcagctgctccttgat attaacatttgtacagagttgaagttgttttttcaagttcttttctttttcatgactatt aaatgtaaaaatatttgtaaaatgaaatgccatatttgacttggcttctggtcttgatgt atttgataagaatgattcattcaatgtttaaagttgtataactgattaattttctgatat ggcttcctaataaaatatgaataaggaannanaaaaanaannnannnnanacttgaaaga cagtggtcggcagcggccttgtggcctttgcaaaggaattcccttaatgcctggtccttg gggcaattgctctgaccattcttggcattgctttatagagatatggaaaaaccacaccag ggtct

>40670_at HG-U95Av2 tgctggtgccttcattcatgaaaagcatgcccatacgattaaacctgcgagatcggagtt ctttaattaggaatggaatgcaacagatttggacaagtcaaggacaagnnntttnnnnnn nnnnannnnnttntcnctgntannnnnnncagtatgtagccgagaacca atggagaaca tcaaatacagtggaacaaatgtaactgctattgatgtcacactttgtgaagtagtctttg ttgcttaaaaagggtgacatctagtggctaaacat

>40671_g_at HG-U95Av2 gactcaattgcagtgatcctgttcagtggggtgcatttttacannnnnnnnnnnnnnnnn nnnnnnnnnnnnnnaaaannnggacaagcgaagggttgttatgttggctttgatctagca catgcagttggaaatgttgaactctacttacatgactggggagttgattttgcctgctgg tgttcctacaagta

>40672_at HG-U95Av2 cagcaccagatttaagatggataacaaactgcagttaatccctggggtctgtggattccg aatttcaaatcctcccattttgttggtctgttccttgcatgcta

>40687_at HG-U95Av2 aaggctctgcagagatgactgggctggggaagcagatgcttgctggccatggannnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnacagacagnntcagcatggaatgctcttggcca agggtactgggggccctctggccttttgcagctgatccagaggaacccagagccaactta ccccaacctcaccctannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn acaggaaaaggcggattgaggctgctgggtcagccttgatngcacagacagagcttgtgc cggatttggccctgtcaaggggactggtgccttgttttca cactccttcctagttctac tgttcaagcttctgaaataaacaggacttgatcacaaanannnnnnnannnannnnnnnn nnnnnnnnnnngggttgggggatagagttattttgcccaggcttcctttacttcttggtc ctgta

>40698_at HG-U95Av2 tcaaaacgctgattaaaagaagcacggtatgatgaccaaacataaaaagtgttttataat tgttggtgttttaataacaactaatattattactctgatagttaaactaactcgagattc tcagagtttatgcccct tgattggattggtttccaaaacaaatgctattatttctctaa agaagaaggagattggaattcaagtaaatacaactgttccactcaacatgccgacctaac tataattgacaacatagaagaaatgaattttcttaggcggtataaatgcagttctgatca ctggattggactgaagatggcaaaaaatcgaacaggacaatgggtagatggagctacatt taccaaatcgtttggcatgagagggagtgaaggatgtnnnnnnnnnnnnnnngatggtgc agcaacagctagatgttacaccgaaagaaa

>406_at HG-U95Av2 acgtgccctacaagttcaaggtgcaggccaggaccactgagggcttcgggccagagcgcg agggcatcatcaccatagagtcccaggatggaggacccttcccgcagctgggcagccgtg ccgggctcttccagcacccgctgcaaagcgagtacagcagcatcaccaccacccacacca gcgccaccgagcccttcctagtggatgggctgaccctgggggcccagcacctggaggcag gcggctccctcacccggcatgtgacccaggagtttgtgagccggacactgaccaccagcg gaacccttagcacccacatggaccaacagttcttccaaacttgaccgcaccctgccccac ccccgccatgtcccactaggcgtcctcccgactcctctcccggagcctcctcagctactc catccttgcacccctgggggcccagcccacccgcatgcacagagcaggggctaggtgtct cctgggaggcatgaagggggcaaggtccgtcctctgtgggcccaaacctatttgtaacca aagagctgggagcagcaca

>40823_s_at HG-U95Av2 gacagcactcaactcaagcacaaagtacgggccaggggggtctttctgcaccttcatcct taatatgtcacagtttgtgtgatnnnnnnnnnnnnnnncctgatggggcaactgtgagca ttaaacctgaaccagaagatcgagagcctaactttgcaaccattggtctgcaggacatca ctttagat

>40899_at HG-U95Av2 cacacggagcagctccagatgagcaggtccgaggttacntgacctgcggcgcacccttca gggtcttgagattgagctgcagtcacagctgagcatgaaagctgccttggaagacacact ggcagaaacggaggcgcgctttggagccnnnnnnnggcgcatatccangcgctgatnann nnnnnnnnnnnnnnnnnnggncgatgtgcgagctgatagtgnnnnnnnnnnnnnnnnnnn nnnnnngctcatggacatcaagtcgcggctggagcaggagattgccacctaccgcagcct gctcgagggacaggaagatcactacaacaatttgtctgcctccaaggtcctctgaggcag caggct

>408_at HG-U95Av2 attaactctacctgcacactgtcctattatattcattctttttgaaatgtcaaccccaag ttagttcaatctggattcatatttaatttgaaggtagaatgttttcaaatgttctccagt cattatgttaatatttctgaggagcctgcaacatgccagccactgtgatagaggctggcg gatccaagcaaatggccaatgagatcattgtgaaggcaggggaatgtatgtgcacatctg ttttgtaactgtttagatgaatgtcagttgttatttattgaaatgatttcacagtgtgtg gtcaacatttctcatgttgaaactttaagaactaaaatgttctaaatatcccttggacat tttatgtctttcttgtaaggcatac gccttgtttaatggtagttttacagtgtttctgg cttagaacaaaggggctta

>41048_at HG-U95Av2 ggaacagttagttctcatctagaatgaaagttccatatatgcattggtgaatatatatgt atacacatacttacatactta atgggtatctgtatagataatntgtattagagtattat atagcttcttagtagggtctcaagtaagnttcattttttttatctgggctatatacagtc ctcaaataaataatgtcttgattttatttcagcaggaataattttatttattttgcctat ttataattaaagtatttttctttagtttgaaaatgtgtattaaagttacatttttgagtt acaagagtcttataactacttgaatttttagttaaaatgtcttaatgtaggttgtagtca ctttagatggaaaattacctcacatctgttttcttcagtattacttaagattgtttattt agtggtagagagntttttttttcagcctagaggcagctattttaccatctggtatttatg gtctaatttgtatttaaaca atgcacacatataaaagttgatactg

>41140_at HG-U95Av2 agctgctagagttctgtctggactttccagagaccagtattcccttttgctgcctctaaa aggcctgtccctgcagacatgagagacagcaggtctcatgggggtgacaagctttttttt ttttncttaaagaattttcaaaatcaaattccagaatgattttacggagatatcccagga aaattaaggcttctcttaaacactaaaaaggcatgtaattgcttgttagcaaaatggata tgacacatctctgatacttttttcattattggttgggctgagcagtcagaagacctggtc gtcgtcttgactttgnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnagggacacngagtggcccttcatgtacatccatggtgtgctggcttaaaat

>41168_at HG-U95Av2 gagaacccgtactctagggccaaatccattcttcttgccctggctcacttgtccccccca , ccgccccgcgctggagccactgcctagttcttcagccctagatggtgctcgccagacctc ctctcaatgctcatcacacacagggctattcctttcctccaatgaaccaaacgcctcccg cccacctccaggtcccagtcctctgttccctttgcctggtccacccttgccctccctggg tcgcaganganggtcggcctcgtcanttccccgcagaccgccgcgcgtccctcttgtgcg gttcaccacagttgtatttaagtgatcgtgtgagtcgtcgttaaatgcctgtctccccgc ggatcatgggctcctngaggnnnnnnnnnnnnnnnnnnnnnnnnnnnnntaaccccgcgc cggcatagggacctaaggcccactggagggcgctcatcaagtagctgctggatgttgacg aaggaagcggcggcgcagctcagggatctccgagtcaggacggtcggccaganccacggg gtaacgggtctaatcgtgtaggaataaagctgtattccagtgcttc

>41171_at HG-U95Av2 tagcaatccaggagaaggtgctggagagggtgaatgccgtcaagaccaaagtggaagctt tccagacaaccatttccaagtacttctcagaacgtggggatgctgtngccaaggcctcca aggagactcatgtaatggattaccgggccttggtgcatgagcgagatgaggcagcctatg gggagctcagggccatggtgctggacctgagggccttctatgctgagctttatcatatca tcagcagcaacctggagaaaattgtcaacccaaagggtgaagaaaagccatctatgtact gaacccgggactagaaggaaaataaatgatctatatgttgtgtggaaaaaaaaaaaaaaa aaaanaannnnaannnnnnnnnnnnnnnnnnnnnnncctgaagatgaatgtggtgggaag gggtgggtgtcacaaagnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnna agaggggattcaggccctttctcatccagtag

>41184_s_at HG-U95Av2 ctatgggcagtatgatctgtggctgggataagaagggtccnnnnnnnnnnnnnnnnnnnn nnnnnnngactcggctctcaggaaatatgttctccacgggtagtgggaacacttatgcct acggggtcatggacagtggctatcggcctaatcttagccctgaagaggcctatgaccttg gccgcagggctattgctt tgccactcacagagacagctattctggaggcgttgtcaata tgtaccacatgaaggaagatggttgggtgaaagtagaaagtacagatgtcagtgacctgc tgcaccagtaccgggaagccaatcaataatggtggtggtggcagctgggcaggtctcctc tgggaggtcttggccga

>41191_at HG-U95Av2 ggcctctcttagctcagttactcaattcatacgtagtattttttaaaataatttta atc tgtgtaccaccccatatatttcatattactgtttcacatgtacagctttctacttctttg taagaacancaaccaaccaannnnggtttaannnnnnnnnnnnnnnnnnnnnnnngggtg gcagatgttctatgcagtgtggttcaagtttctttgaccgcacttatatgcattgctaat atggaatttaagataccatacacagtctctcatggacctatctctattgtagaattatga cttatgtcttacttgncaaatttttctgaatgtgacctttttttgctgatttgctgggtt tgggattaactagcattat ttgccacctttatattgtatttataaaaaaaaagtactat caatcaatcatactactttggattgttg

>41237_at HG-U95Av2 cctgactttgtttctgcaaaggcacctgcatgtgtctgtgttcntgtaggcataatgtga ggaggtggggagaccaccccacccccatgtccaccatgaccctcttcccacgctgacctg tgctccctccccaatcatctttcctgttccagagaggtggggctgaggtgtctccatctc tgnctcaacttcatggtgcactgagctgtaacttnttccttccctattaaaattagaacc tgagtataaatttact tctcaaattcttgccatgagaggt

>41239_r_at HG-U95Av2 tttgcaaatctcaggataaagtttgctaagtaaattagtaatgtactatagatataactg tacaaaaattgttcaacctaaaacaatctgtaattgcttattgttttattgtatactctt tgtctttttaagacccctaatagccttttgtaacttgatggcttaaaaatacttaataaa tctgccatttca

>41266_at HG-U95Av2 agtctcagtttcttgcttggggaacttgtgtccctaatgtgtttagattgctagattgct aaggagctgatactttgacagtgtttttagacctgtgttactaaaaaaaagatgaatgtc ctgaaaagggtgttgggagggtggttcaacaaagaaacaaagatgttatggtgtttagat ttatggttgttaaaaatgtcatctcaagtcaagtcactggtctgtttgcatttgatacat

>41294_at HG-U95Av2 gtgaatatctctgtgatgaattccactggtggcagtagcagtggcggtggcattgggctg accctcgggggaaccatgggcagcaatgccntgagcttctccagcagtgcgggtcnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaggagtncccgcgactga gccgcctcccaccactccactcctccagccaccanccacaatcacannnnnnnnnnnnnc cnttgccgaggctgaggagtgtggggagctggnnnnnaagnatncncgngccnngcagga ggnagctggaagcngccctgcagcgggccaagcaggatatggcacggcagctgcgtgagt accaggaactcatgagcgtgaagctggccctggacatcgagatcgccacctaccgcaagc tgctggagggcgaggagagccggttggctggnagatggnagtgggnagccgtgaata ct ctgtgatgaattc

>41352_at HG-U95Av2 gttctgatttgacacactgattttaatcttcgaatcatgacactgagtgcagaggaggtg gcattccgacagcaggacatacatgttggtgtgaagactgggacgacactgggtagaatc tagtttttaattattattaatataaaggatcaaattaatttaaatatgattctgaagtct acagaacttttagttctgtgctgtctatgtggacactttggtaaaatgcaaattatgata tggacgttatcattggtctggtgagatgtttcatatttgtgacagttaatttaaaaatta tganttaatgctgcctgtgtctatggggttctgtcttctttgatagccatctattcatct ggatcatgggaccctctctaatccttccaccaatcaaataagctattgctattggtttgg agttgagatatcagtctcggaaactt

>41362_at HG-U95Av2 cacaactggggcagaatttaaagctgcaacacagctggtgatgagaggctncctcagtcc agtcgctccttagncnccaggcaccgtgggnccnggatggggaactgcaagcannctctc agctgatggctgcncagtncagatgtctggtggcagagagtccgangcatggagcgattc cattttatgactgttgtttttcacattttcatctttctaaggtgtgtcncttttncnann nnnannnnnttttnnnannccaaaagtcgatcaatcgcattcattttaagaaattatacc tttttagtac tgctgaagaatgatnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnatagacagcacttgtgaaggattgaa tgcaggttccaggtggagggaagacgtggannnnnnnnnnnnnnnnncatgcagacattt ttaaaagctatacaaaaaattgtgagaagacattggccaactctttcaaagtc

>41384_at HG-U95Av2 ttcttgtttataacagtgccttaaggtatgatgtatttctgatggaagccattttcacat tcatgttcttcatggattatttgttacttgtctaagatgcaatttgattttatgaagtat ataccctttacccaccagagacagtacagaatccctnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnngttattaatttaaaactccattattaggattacattttaaagttttatt tatgaattccctttaaaaatgatatttcaaaggtaaaacaatacaatataaagaaaaaaa taaa atattaataccggcnnnnnnnnnccatttttaacctcagccttccctactgtcac caacaaccaagctaaataaagtcaacagcctgatgtg

>41419_at HG-U95Av2 ctcattggaattttcttcaagtgttaaaggtacattttcactaggaaaagaaatcaaata tgcttatgcaatat tatttgtgtgtttttccttaatgtta atggtatatatgagcctt cttgtttagtttcttttatctgctaagttgtaccttaattagagggcaatatatgtttca taaagaagagtctttataantttgtttgtcagatagtatttnggaanttgtataataagg atgtttagaagccatataagtggctttttttaacagatagaatttgtatttttattgtac tttaaaaagatttatgtaataggtatatatttagtggccatttattatcaatggtaacac aatggagtactaagatggtatttgcacatttaagatatgttactttaccaatttttaatg gtaatcaactctgctactggcatgatgaaatagtacataactggtcattaattatgaaca ttta'nttctccagtgcgtttttatgaagatctggttgaaaattgtatttctatgtaaact caacgatatgtttggttttcctg

>41433_at HG-U95Av2 caaagtaaaacttgctgcctgaagancagtanctnccatcangatgagagaactggagga gttccttgatctgtatatacaataacataatttgtacatatgtaaaataaaattatgcca tagcaagattgcttaaaatagcaacactctatatttagattgttaaaataactagtgttg cttggactattataatttaatgcatgttaggaaaatttcacattaatattnnnnnnnnnn nnnnntttgtcatctttcttctattttattccctttcacaaaattttattcctatatagt ttattgacaataatttcaggttttgtaaagatgccgggttttatatttttatagacaaat aataagcaaagggagcactgggttgactttcaggtactaaatacctcaacctatggtata atgg

>41439_at HG-U95Av2 ctgtttctggtaaataccatatatga cctcgaaatgataatatctccannnnnnnnnnn nnnnncaaatttgagtagatattttaaacacctaacaaagtaaagggctaaaagccattc agatagcagtaaaacattctgtatgatgtgcaataaaacatccaagatcttttttgaaag ttttatttataatatacatttttgtatgagaaaggtgattggtacagggtgcctatttta gtcatggatcaaaatttgtgtaacttgcagggctttctttctttttcttcaaatttacaa gggttcattttggaaactacattttaaactttggaatcaaattgtttcttatttgggagg ataatgtatatacattggtattatgttaaataataaaattgttctaatttggtgccannn nnnnaaaaaaaaannnnanntttgnatctcaagctattttcatatgttatgtgtcaatgt atcatctctcagaaaggttttacaatccaaacat atatgttctctgtgtaactgaattt cacttatcttttataaaccagaaacattaattgaaaanannttctggggattttctcttg acttgta >41446_f_at HG-U95Av2 ctggtgtctcctgcacctgcgctggttcctgcaagtgcaaagagtgcaaatgcacctcct gcaagaagagctgctgctcctgnctnncccgtgggntgtagcaagtgtgcccagggctgt gtttgcaaaggggcgtcagagaagtgcannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nncagatgtaaacagagagacatgtacaaacctggnnnttttttttttataccaccttga cccatttgctacattccttttcctgtgaaatatgtgag

>41475_at HG-U95Av2 ggaccagcccttgctctgactgcggccaagcaccacgcaggaggccactcttgtctctca gcagctgttcccaggnggnagctccctnctnggcacatgggggctggncacaatagccca gagggtcagaactggacagctgcagagacctgtgcccagagaanggtctcgacccactca aggacacacagcaggtccgtggatgggctggatgagtgaccagggccagcctctgtctca ggacattccagaaggacaaggagatgtctctccctctcccaaagcaccagcgtccctgcc tcccgtgggccctgtccgggttgccctggtgaccccagcctctgtccacttcctaaccca gggaccctgcacagccagaactncctttggccctacggatggccactggctctggtctaa agtgcctgggcttggtggccatcaagagggagccagtcaggcctgtgagggccgtagacc ttgtatataccctgcaccagcagtgaccgggcagagcc

>41534_at HG-U95Av2 catccatacattactgtgtttggctgaattccactctaatatgatgctccnattatgcac catactgtgatgacctttctactccgaaacctgctggagcctnccnttggccgtggggtg tcagccaatcactgcttgttccacttgttgtacattttatttttgagtctttttctttct catatacagaaaaatagtatgaaaataaaataaatgtatgaaacagtattaatgcagaaa tgtgctact atggatgtctgagtcaccagaaattccattcttaaagaggcggttagcac ctattagacgtaacagtgatgtcttttaaaaaatccaaaagcatattgcaacaataagtt tgagactttgtgtgaacaaagggaaattcagcctcttatgtctttg

>41554_at HG-U95Av2 gtccacagttattcaaacaatggctttttttgtgatgagagtatttgttaaaaaaaaaaa aaagacttcaagaaaaataaaagttcagtggagctgcaaataaatctggtgaataatttc atctttggtaatctcccatttcctgagttcttcctcaatccaagctgtcctgtgtagtat ataacatttgggcattttctctgatatactatactctcatgttctataaatttctgtccc gtaattctaacactttacattttttctttgcta cagcta agctattcatggaagggaa gaatcactaaatacttgtctagttatagnnnnnnnnnnnnnnntcctccttatccctcga tgcctggcttggtgtctggcaaacagtccataattagcagatgttgaaagaccgtttaca aagcagaatttggggatttaaagtgcaatgatacaacaaaaagatttaattacagcttcc agtgttttgactatgtgaaccat

>41592_at HG-U95Av2 agctgtgccgccagcgcatcgtggccaccgtgggccgcgagaacctggctcgcatccccc tcaaccccgtcctccgcgactacctgagntncnnnncnnnncnnnnnnnnnnnnnnnnnn ccgccgtgcacgcagcattaactgggatgccgtgttattttgttattacttgcctggaac catgtgggtaccctccccggcctgggttggagggagcggatgggtgtaggggcgaggcgc ntcccgccctcggctggagacgaggccgcagaccccttctcacctcttgagggggtcctc cccctcctggtgctccctctgggtccccctggttgttgtagcagcttaactgtatctgga gccaggacctgaactcgcacctcctacctcttca gtttacatatacccagtatctttgc acaaaccaggggtt

>41601_at HG-U95Av2 gacccacaagcagatatttgaattacttcttnnnnnnnnnnnnnnnnnnnnnggatgggc tgcatttactgtgtgaaggataaaaatcattagcctggattctgatttctataaattgcc attaaaagctttttttcccctaagaactgaaatgtgctcaccagccaaaacattttaact tgtaaattttgagggcagttaaccaaacctgtgactaatcatatctcctcctacccccca tttccaaggacatttgttactcagatacttgttatactaatacttgaacttgtaccttat ggtatttgctatcttttaactagtcatgatattcttatactttagttacacttttggaat t gatacaaggttgagtggggtgtgtgggtgtatgtatgagtgaaacagttctcaaaaga atgtaagaaaaaccatttt ataaaattgtgactttttaaaaacatagtctttgtcattt atagaattaacaagctgctcagggtatattttatagctgtagcactgatatc

>41612 at HG-U95Av2 atcttgttttacactcccatgggtccttcaggctctcatcttttttctttttccagtcta ttttcnnnnnnnnnnnnnnnnnttaatttttattgaccttccatggtcctcactgattgt tttctttgtcanacctaanctgttgnagtttgtgncagtgagttttncattttggttttg tattttnccagttgtttnaatttnccattgggtgggttcttttgtnacaccttctgtttc tttgncttattttttaacgnccaaagaaagactctcagagaatagacaactatattccaa agtcatggttctctggtggtttgtcttgacatttgaatagaaatgttaaactatctgggg gaatagaaagcccacagtcttctgagttgtgctacaccaatatttctatgaacagatctt acaactgagagtgatctgcagatttttcagagtcatgttctcc

>41635__at HG-U95Av2 gctctatattacttgcttgagccttaatcaatgtggttttattcaatggtttgttctttg aatggttgcaaaaactgtagataatcttactgaggactgtacaaacatgaaggtgtggta tcaaacttcaggnnnnnnnnnnnnnnnnnattataaacattcatttcacaactagattgt ataaggatattagctgtgatgagactcactgcattattttttttagtgaattttatgaaa tccccgttccattcaacaggcacatgtttaaaagagctttgtcgttggtgttaatggggg aatgtgttccttcattgtatttgggccttttgtattgcactcttgat

>41654_at HG-U95Av2 aaaggctgaacatcaatgcggccaaatctagtttcctcccagaagatgaaaagagggagc ttctcgacctgctctataaagcctatgggatgccaccttcagcctctgcagggcagaacc tctgaagacgccactcctccnnnnnnnnnnnnnnnnnnnnnnnnnnnactctgtggggct gagcaacatttttacatttattccttccaagaagaccatgatctcaatagtcagttac g atgctcctgaaccctatgtgtccatttctgcacacacgtatacctcggcatggccgcgtc acttctctgattatgtgccctggccagggaccagcgcccttgcacatgggcatggtt

>41656_at HG-U95Av2 tgtacccgcgactaactagacttttctgctgttgtgcaaagttcagtttcttctcagcaa catcaaggatatatgaagaaaaggaaataaaaaactgtaaagtcaaaagagatgcctggt ggaacttattcgtgctatcagggcattgatagtttgaatgtttttattactta gcaaaa ttgcacatactcctctatnctgattttatcatgaaaactgtcatgtgtcatgctaatgga

>41677_at HG-U95Av2 agcaagctcaccaggcctctcagaagtcccagnnnnnnnnnnnnnnnngccgggtcggcg cctcctgcgcgagggagcaggttctccgcattcccatgggcaccacctgcctgcctgtcg tgccttgganncnnnncccngnnnnnnaggagagaccaaaggcttctgagcaggattttt atttcattacagtgtgagctgcctggaatacatgtggtaatgaaataaaaanccctgncc ccgaatcttccgtnccctcatcctaacttncagttcacagagaaaagtgacatacccaaa gctctctgtcaattacaaggcttctcctggcgtgggagacgtctacagggaagacaccag cgtttgggcttctaaccaccctgtctccagctnctctgcacacatggacagggacctggg aaaggtgggagagatgctgagcccagcgaatcctctcnnnnnnnnnnnnnnngaagaaga aaactcaactcagtgccattttacgaatatatgcg

>41711_at HG-U95Av2 catcccagtgttatgtaaagatggtgtgcctgagggagcccccacagctggtgc gggcc tgcatttccttggccccaacgcaggcgaagttactnnnnnnnnnnnnnnnnnnnnnnant gnggggcttcctatgcgcaggtgatgcggaccgtgggtatccatcccacatgctctgagg aggtagtcaanntgcgcatctccaagcgctcaggcctggacnnnnnnnnnnnnnnnnnnn nnnnntaagcgccatccctgcaggccnagggcacacggtgcgcccgccgccagctcc cg gaggccagacccaggatggctgcaggccaggtttggggggcctcaaccctctcctggagc gcctgtgagatggtcagcgtggagcgcaagtgctggacaggtggcccgtgtgccccacag ggatggctcaggggactgtccacctcacccctgcacctctcagcctctgccgccgggcan ccccccccaggctnntggtgccnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnntccgagccccctggcatttctgcaatgcaaata

>41742_s__at HG-U95Av2 gcagtccttgatggagatgcagagtcgtcatggggcgagaacaagtgactctgaccagca ggcttaccttgttcaaagaggagctgaggacagggactggcggcaacagcggaatattcc gattcattcctgccccaagtgtggagaggttctgcctgacatagacacgttacagattca cgtgatggattgc

>41743 i at HG-U95Av2 actggaactggcagagaaggctctggcttccaaacannnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnngcaggaagaggacctggaaaccatgaccatncnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnaaattcatgaggaa aaggagcaactgnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnaggcaggcagtccttgatggagatgcagagtcgtcatggggcgagaacaagtgactct gaccagcaggcttaccttgttcaaagaggagctgaggacagggactggcggcaacagcgg aatattccgattcattcctgccccaagtgtggagaggttctgcctgacatagacacgtta cagattcacgtgatggattgcatcatttaagtgttgatgtatcacctccccaaaactgtt ggtaaatgtcaga

>41816_at HG-U95AV2 tctctcctgtgtaaatgtcacgccccacccctgtttcatgtgggcactaacacgtgtgcg ttcctggcgggcacactcaggaccgtgcctcacagggcccactccctgcctatgcctccc tcttggggggccgaggagggcggctgctctgtcatgagaatgtacggcccgtggatgatt aacgggcctttttcacttagaagctg

>41831_at HG-ϋ95Av2 cgtccagcacgaaggccacgctgtacccgccgatcctgaacccgccgccctccccggcca cggacccctccctgtacaacatggacatgttctactcttcaaacattccggccactgcga gaccgtacaggccctacatcattcgaggaatggcgcccccgacgacgccctgcagcaccg acgtgtgtgacagcgactacagcgccagccgctggaaggccagcaagtactacctggatt tgaactnggactcagaccccta ccacccccacccacgccccacagccagtacctgtcgg cggaggacagctgcccgccctcgcccgccaccgagaggagctacttccatctcttcccgc cccctccgtccccctgcacggactcatcctgacctcggccgggccactctggcttctctg tgcccctgtaaatagttttaaat

>425_at HG-U95Av2 gctctcacctcatcagcagtgaccagtgtggccaaagtggtcagggtggcctctggctct gccgtagttttgcccctggccaggattgctacagttgtgattggaggagttgtggccatg gcggctgtgcccatggtgctcagtg

>463_g_at HG-U95Av2 ttgccaaactgcgcaaagatattcgccaggagtatcgagaggactttgtgctcaccgtga ctggcaagaagcacccgtgctgtgtcttatccaatcccgaccagaagggtaagattagga gaatcgactgcctgcgacaggcagacaaagtctggcgtctggatctagtcatggtgatcc tgttcaaaggcatccccttggaaagtaccgatggagagcggctcatgaaatccccacatt gcacaaacccagcactttgtgtccagccacatcatatcacagtatcagttaaggagctt

>464_s_at HG-U95Av2 gggcctagcagtcttcacctctgagtcaggctaggggcctccccttctcatcctccccac ccccccgccaaggttctcacactggcctgggcttgggtgcccatataggaggtctgtatg ttcaccaacagtgcggaggggtcacacattgcaaaacactgcccagaacagtaaaaagag

> 81_at HG-U95Av2 gaagacttggccaagaagtattttgctcagatagttcatgctatatcttattgccataaa ctccatgtggttcacag

>535_s_at HG-U95Av2 tgatttcaaattgaactcctccattgtggaacccaaggagccagccccagaaacagctga tggcccctacctggtgatcgtggaacagcctaagcagagaggcttccgatttcgatatgg ctgtgaaggcccctcccatggaggactgcccggtgcctccagtgagaagggccgaaagac ctatcccactgtcaagatctgtaactacgagggaccagccaagatcgaggtggacctggt aacacacagtgacccacctcgtgctcatgcccacagtctggtgggcaagcaatgctcgga gctggggatctgcgccgtttctgtggggcccaaggacatgactgcccaatttaacaacct gggtgtcctgcatgtgactaagaagaacatgatggggactatgatacaaaaacttcagag gcagcggctccgctctaggccccagggccttacggaggccgagcagcgggagctggagca agaggccaaagaactgaagaaggtgatggatctgagtatagtgcggctgcgcttctctgc cttccttagagccagtgatggctc

>543_g_at HG-U95Av2 gaatatgtcatagttctgagctgccagtggaccgcccttttcccctaccaatattaggtg atcccgttttccccatgacaatgttgtagtgtcccccacccccacccccctggccttggt gcctcttgtatccctagtgctgcatagcccggcatttgcacggtttcgaagtcattaaac

>544_at HG-U95Av2 ggtgaagaccttgctgctaaatgctgctcagaacaccatggagccacccctgaccccgcc cagcccagcagggccgggactgtcacttggtgatacagctctgcagaacctggagcagct gctagacgggccagaagcccagggcagctgggcagagctggcagagcgtctggggctgcg cagcctggtagacacgtaccgacagacaacctcacccagtggcagcctcctgcgcagcta c

>545_g_at HG-U95Av2 agtggcagcctcctgcgcagctacgagctggctggcggggacctggcaggtc actggag gccctgtctgacatgggcctagaggagggagtgaggctgctgaggggtccagaaacccga gacaagctgcccagcacaacagaggtgaaggaagacagtgcgtacgggagccagtcagtg gagcagaaggcagagaagctgggcccaccccctgagccaccaggagggctctgccacggg cacccccagcctcaggtgcactgacctgctgcctgcccccagcccccttcccggaccccc tgtacagcgtccccacctatttcaaatcttatttaaca

>570_at HG-U95Av2 actgacactggactcgtaccaggccccgggccccggggatggaggcaccgccagccttgt gggcagcaacatgttccccaatcattaccgcgaggcggcctttgggggcggcctcctatc cccggggcctgaagccacgtagccccgcgatgccagaggaggggcactgggtggggaggg aggtggaggagccgtgcaatcccaaccaggatgtctagcacccccatccccttggccctt cctcatgcttctgaagtggacat ttcagccttggcgagaagctccgttgcacgggtttc cccttgagcccattttacagatgaggaaactgagtccggagaggaaaagggacatggctc ccgtgcactagcttgttacagctgcctctgtccccacatgtgggggcaccttctccag a ggattcggaaaagattgtacatatgggaggagggggcagattcctggccctccctcccca gacttgacttgaaggtggggggtaggttggttgttcagagtcttcccaataaagatgagt ttttgag

>574_s_at HG-U95Av2 actctgagcaagtcccagatatactacaactcaatgcaatctttaacatgttgaatacca agaactgcccaagtttgaaggacaaaccgaaggtgatcatcatccaggcctgccgtggtn ncagccctggtgtggtgtggtttaaagattcagtaggagtttctggaaacctatctttac caactacagaagagtttgaggatgatgc attaagaaagcccacatagagaaggatttta tcgctttctgctcttccacaccanntaatgtttcttggagacatcccacaatgggctctg tttttattggaagactcattgaacatatgcaagaatatgcctgttcctgtgatgtggagg aaattttccgcaannttcgattttcatttgagcagccagatggtagagcgcagatgccca

>576_at HG-U95Av2 atcggcgtgctgcgggatcagcaacgctaccacgaagacattttcgggctcacgctgcgc acccaggaggtgacaagccgcatacgcacccagagcttttccttgcaggagcgtcagttg cggggcgcagtgccctgggcgttcgaccctcccggctcagacaccaacagcccctgagag ccgcctggctttcccttccagttccgggagagcggctgcccgactcaggtccgcccgacc aggatcagccccgctcctcccctcttgaggtggtgccttctcacatctgtccagaggctg caaggattcagcattattcctccaggaaggagcaaaacgcctcttttccctctctaggcc tgttgcctcgggcctgggtccgccttaatctggaaggcccctcccagcagcggtacccca gggcctactgccacccgcttcctgtttcttagtccgaatgttagattcctcttgcctctc tcaggagtatcttacctgtaaagtctaatctctaaatcaagtatttattattgaagattt accataagggactgtgccagatgttaggagaactact

>583_s_at HG-U95Av2 tgcccatctatgtcccttgctgtgagcaagaagtcaaagtaaaacttgctgcctgaagaa cagtaactgccatcaagatgagagaactggaggagttccttgatctgtatatacaataac ataatttgtacatatgtaaaataaaattatgccatagcaagattgcttaaaatagcaaca ctctatatttagattgttaaaataactagtgttgcttggactattataatttaatgcatg ttaggaaaatttcacattaatatttgctgacagctgacctttgtcatctttcttctattt tattccctttcacaaaattttattcctatatagtttattgacaa

>590 at HG-U95Av2 tccgtggcaatgagactctgcactatgagaccttcgggaaggcagcccctgctccgcagg aggccacagccacattcaacagcacggctgacagagaggatggccaccgcaacttctcct gcctggctgtgctggacttgatgtctcgcggtggcaacatctttcacaaacactcagccc cgaagatgttggagatctatgagcctgtgtcggacagccagatggtcatcatagtcacgg tggtgtcggtgttgctgtccctgttcgtgacatctgtcctgctctgcttcatcttcggcc agcacttgcgccagcagcggatggg

>595_at HG-U95Av2 aaagccagtaaccatgagtatgaggaaatctctttctgttgctggcttacagtttctctg tgtgctttgtggttgctgtcatatttgctctagaagaaaaaaaaaaaaggaggggaaatg cattttccccagagataaaggctgccattttgggggtctgtacttatggcctgaaaatat ttgtgatccataactctacacagcctttactcatactattaggcacactttccccttaga gccccctaagtttttcccagacgaatcttta aatttcctttccaaagataccaaataaa cttcagtgttttcatctaattctcttaaagttgatatcttaatattttgtgttgatcatt atttccattcttaatgtgaaaaaaagtaattatttatacttattataaaaagtatttgaa atttgcacatttaattgtccctaatagaaagccacctattctttgttggatttcttcaag tttttctaaataaatgtaacttttcacaagagtcaac

>626_s_at HG-(J95Av2 cgggctctgctctgatcacctt gatgaccccaaagtggctgagcaggtgc gcaacaaa aggagcacacgatcaacatggaggagtgccggctgcgggtgcaggtccagcccttggagc tgcccatggtcaccaccatccaggtgtccagccagttgagtggccggagggtgttggtca ctggatttcctgccagcctcaggctgagtgaggaggagctgc ggacaagctagagatct tctttggcaagactaggaacggaggtggcgatgtggacgttcgggagctactgccaggga gtgtca gctggggtttgct gggatggagtggctcagcgtctgtgccaaatcggccagt tcacagtgccactgggtgggcagcaagtccctctgagagtctctccgtatgtgaatgggg agatccagaaggctgagatcaggtcgcagccagttccccgctcggtactgg gctcaaca ttcctgatatcttggatggcccggagctgcatgacgtcctggagatccacttccagaagc ccacccgcgggggcggggaggtagaggccctgacagtcgtaccccaag

>669_s_at HG-U95Av2 gagaccagtg atcaggtcagggacttggacaggagtcagtgtctggctttttcctctga gcccagctgcctggagagggtctcgctgtcactggctggctcctaggggaacagaccagt gaccccagaaaagcataacaccaatcccagggctggctctgcactaagagaaaattgcac taaatgaatctcgttcccaaagaactacccccttttcagctgagccctggggactgttcc aaagccagtgaaatgtgaaggaaagtggggtccttcggggcgatgctccctcagcctcag aggagctctaccctgctccctgctttggctgaggggcttgggaaaaaaacttggcacttt ttcgtgtggatcttgccacatttctgatcagaggtgtacactaacatttcccccgagctc ttggcctttgcatttatttatacagtgccttgctcggcgcccaccaccccctcaagcccc agcagccctcaacaggcccagggagggaagtgtgagcgccttggtatgacttaaaattgg

>706_at HG-U95Av2 TIGRSequence

>712_s_at HG-U95Av2 TIGRSequence

>717_at HG-U95Av2 gttcggatttgactgcctgtatatgttttgtgaaatggtcctgtttttgggtaggtgaca cgtggactctagtatgtaaatgttacttgaatctgtgcttcataatagtgtgtggcatgt atgtgcagactcttggatgctttatgcctgcgcaccaggagccctgtcctcacgttccca ggagggcggcttcacccttcgtaaccaggagacaaggcggccatggatttgcccttgatt ctattttgctaatggaagatagaaaggagagaaggtttttttttttttttaacattctga agatggtgctgtgtcaagaaggaccttttttttcccctctcccctattttttaagtacct tggaggaggagaggttggtgacatgcatggtggggatctatggcctctggtgctt

>823_at HG-U95Av2 acctgaggggcctcttatgggctgggttctacccaggtgctaggaacactccttcacaga tgggtgcttggaggaaggaaacccagctctggtccatagagagcaaaacgctgtgctgcc ctgcccaccctggcctctgcactcccctgctgggtgtggcgcagcatattcaggaagctc agggccctggctcaggtggggtcactctggcagctcagagagggtgggagtgggtccaat gcactttgttctggctcttccaggctgggagagcctttcaggggtgggacaccctgtgat ggggccctgcctcctttgtgaggaagccgctggggccagttggtcccccttccatggact ttgttagtttctccaagcaggacatggacaaggatgatctaggaagactttggaaagagt aggaagactttggaaagacttttccaaccctcatcaccaacgtctgtgccatttt

>848_at HG-U95Av2 tccaggctcgtcattggaggtgaacaagcaaacccagacggctccactaggacttcaaat tgggggttggatttgaagacttttaagtttccttccagcccagaaagtctctcattctag cctcctggcccaggtgagtcctagagctacaggggttctggaaacattcaggagcttcct gtcctcccagctcctcactcaccttcagtaacccccactggactgacctggtccacaggg cacctgccaccctgggcctggcagctcagcttcccaacacgcaggagcacacccagcccc cacatcctgtgcctccatcagctaaacaccacgtcacttcatgcaggtgaaacccagtca ctgtgagctcccaggtgcagccagaggcacctcaaga

>849_g_at HG-U95Av2 tttggtgctttccagaatcccgtaacacctgattaactgaggcatccacttctttcagca gactgatcaggacctccaagccactgagcaatgtataaccc

>873_at HG-U95Av2 atagcgcctgtataagtagatctgctttctgttcatctctttgtcctgaatggctttgtc ttgaaaaaaaatagatgttttaacttatttatatgaagcaagctgtgttacttgaagtaa ctataacaaaaaaagaaagagaaaaaaaaaaacacacaaaaagtcccccttcaatctcgt ttagtgccaatgttgtgtgttgcactcaagttgtttaactgtgcatgtgcgtggaagtgt tcctgtctcaatagctccaagctgttaaagatattttta tcaaactaccta attcctt gtgtaattaatgctgttgtagaggtgacttgatgagacacaacttgttcgacgtgtagtg actagtgactctg gatgaaaactgtgactccaagcggtgtgtccctgcgtgcctttata ggaccctttgcacgaactctggaagtggctcttataagcgcagcttcagtgatgtatgtt t

>874_at HG-U95Av2 gagcagtttgccctgggttccctccttccacctgcgttcctcctctagctcccatggcag ccctttggtgcagaatgggctgcacttctagaccaaaactgcaaaggaacttcatctaac tctgtcctccctccccacagcttacagaccattgtgg

>875_g_at HG-U95Av2 tgggttcaggattccatggaccacctggacaagcaaacccaaactccgaagacttgaaca ctcactccacaacccaagaatctgcagctaacttatttttccctagctttccccagacac cttgtttattttattataatgaattttgtttgttgatgtgaaacattatgccttaagtaa tgttaattcttatttaagttattgatgttttaagtttatctttcatggtactagtgtttt ttagatacagagacttggggaaattgcttttcctcttgaaccacagttctacccctggga tgttttgagggtctttgcaagaatc

>925_at HG-U95Av2 gaggcctgcgtgttggatgaacttgacatggagctagccttcctgaccatgtctggcatg gcatggaagagtttgaggacatggagagaagtctgccactatgcctgcagctctacgccc cagggctgtcgccagaac atcatggagtgtgcaatgggggaccgcggcatgcagc cat gcacgccaacgcccagcggacagatgctctccagccaccgcacgagtatgtgccctgggt caccgtcaatgggaaacccttggaagatcagacccagctccttacccttgtctgccagtt gtaccagggcaagaagccggatgtctgcccttcctcaaccagctccctccggagtgtttg cttcgagtgttggccggtgggctgcggagagctcatggaaggcgagtgggaactcggctg cctgcctttttttctgatccagaccctcggcacctgctacttaccaactggaaaatttta tgcatcccatgaagcccagatacacaaaattccacccctagatcaagaatcctgctccac taagaat

>943_at HG-U95AV2 gacggtataacacatctactgaaaaagcaacgggaaatgtggtcctatttaagccagccc ccacctagggtctatttgtgtggcagttattgggtttggtcacaaaacatcctgaaaatt cgtgcgtgggcttctttctccctggtacaaacgtatggaatgcttcttaaaggggaactg tcaagctggtgtcttcagccagatgacatgagagaatatcccagaaccctctctccaagg tgtttctagatagcacaggagagcaggcactgcactgtccacagtccacggtacacagtc gggtgggccgcctcccctctcctgggagcattcgtcgtgcccagcctgagcagggcagct ggactgctgctgttcaggagccaccagagccttcctctctttgtaccacagtttcttctg taaatccagtgttacaatcagtgtgaatggc

>962_at HG-U95Av2 cttcccagctcttagaaatgtgctacgatgtctgtgaaggcatggccttcttggagagtc accaattcatacaccgggacttggctgctcgtaactgcttggtggacagagatctctgtg tgaaagtatctgactttggaatgacaaggtatgttcttgatgaccagtatgtcagttcag tcggaacaaagtttccagtcaagtggtcagctccagaggtgtttcattacttcaaataca gcagcaagtcagacgtatgggcatttgggatcctgatgtgggaggtgttcagcctgggga agcagccctatgacttgtatgacaactcccaggtggttctgaaggtctcccagggccaca ggctttaccggccccacctggcatcggacaccatctaccagatcatgtacagctgc ggc acgagcttccagaaaagcgtcccacatttcagcaactcctgtcttccat

Table 2b: Probe sequences for identification of transcripts of Table lb

>1529_at HG-U95Av2 aattactgtatctaaaaggagctgctatgaagtacctttcttatgttgctaggctactgt ttctgaaagccctggatctctttgcaccaaaaatggtccagatagactctttttaaggat cttggctgctttttactagaaggttgcttttatgagcatatttatactgctgaaggatga gtgttaattttaattaactttgccgttttgtagagaaaactattcacaagataaattcca agtcttttcacctgtcaggcatgca

>31849_at HG-U95Av2 aaattcacag actccattttggggtccaaactgtaatgctcaaaataataaatgcttac acgaaaattatttattgagaatattcatataaaaattacctaaagcaaagtaaaaaaagt aaaatcaaggtggtatatttgaagtgaatggtgattggaaatttttagctgtaacaaaaa gaaagaaaacaactttttttaaagcctcattctcttttctttcaaaatgtaccttattcc cacacactcttgggctgacctttattttatcaataagctcaatattactttgtttaaaat aagannnnnnnnnnnnnnncattctctctttaaccatataatttaaaaactcctcttcac gattga agcaaaatcagaaacgttaggnnnnnnnnnnnnnnnnnnnnnnnnnnntaagt tggaaaaactattattaataatattatcctatccatccatatctattgaaattgtacagg tccataatttcattttaattaattataggaaagaagaaaagataatacccatttgttcta tcacccctctccctatcattaactatcaaataaataaataaaagcaatctgatttccaac gtggta

>32110_at HG-U95Av2 atgatctgccagagcctctccaggggtggaatacatgnccnggactaagnccaatgacan ccttnccatctttnccagctatggtgactgggttaggtatgatncttgtgagttaagaca atgaagnccagagggaatttcaagacttatgggaatgctgggtagaagctgttttaattc ccctgttgaatgtgaaaaaggtagtagtattcctgggtctttatgatgaccaccttgggc cttgggatcatgaccaggaatcacgtgaagctgacaccactgaagggagagttgagaggc agaaagagatcaagtccttggtgaaattgtttaagtacaggatcaagccttgcttgagat tggccttacct

>32385_at HG-U95Av2 gtcatcttgtaattctatgtgtaactttggaggaatttccaaactgttttctgcaatggc tgcaccattttacattcctgtcagcaatgtacaggattccagtttctccatatccctgcc aacacttggtattttcctttttttcagttagttactctagtgggtatgtggtggttgtcc cattgctgtttgttttgattttcattgtccctaatgactaatgat ttgagcatctaata tccagttgtcccagcaacatttgtttgaagagactattctttcctgtgtaaatggtcttg gcatctttgttgaaaatcgattggcagccaggtgcagtagctcacacctgtaatcccagc actttgggaggctgcgctgggcagatcgcttaagct

>32791_at HG-U95Av2 ttgtaaacagatcatcctaggcgaaagttttttttgtttgtttgcttttaaattagttta tttctaaatcttagtcttccacatttctagaggccacctgacacaagtccctgtatctga agtctannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnagtggataact taatcttttaatacagttccgtcattcccatcttgttttcagaagagaaggtnnnnnnnn nnnnnnnnaacatatccactgtgtgcatagagggtctcttcacgttgatgcttggcattc ca cagctttctctaagtctt gctcaagttcaaccttaaaatgatgttagacaacaggt cccagtcagttccctctattttcacccattttgctcacaagccatattggcccgattagt ggtactgtctgactcacgtgtgtgatccaaataaaggtagctgctgaccannaaanaaaa aaaaaaaaaaaaaannnnanananaanccagggttctctcatgaggagttaa

>33325_at HG-U95Av2 catcccaaagtcaaacatgggcaagaggtgannnnnnnnnnnnnnnnnnnnnnnnnnntt tgtctgtgattttaaactaactgtgtatgtattgatgtttggaagattgtttgaatttta aagtgataatagtacttaatgttatccagtattgttcattaaatggtgttatcctaaagc tgcacttgggatttttacctaacgctttactgattctctcaagcacatggncaaagtttg antttgcactccgttcatttctgacacgttttgctgncctcctacctttctaagcgtcat gcaaattcgagaatggagaaggacgctgccggtccctgagcggtgtggagagggcggaag gtggactccagcgcagcttgaggggctgaggacggaggctgcagcatctgtgtcgttcta ctgagcacgcttctctgcctcgctcctgacnnnnnnnnnnnnnnnnnnnntcagcagtta tgtttacacatcatttttatgttcctgctttgtaattcatgtttgagatgggtggccact gtaca

>33924_at HG-U95Av2 gtcgcattaatgaggcccttccacatcatttttaaactaatgtttttctatattaacatt attatggatatttggctttcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnncccatgc tccaatcaaagggatttttagtagtgcctctaagcaagcaccgatgagtcagtcccacgt attttcttttttgtcagtattgtttgggaaggagacatgccgggatgtgtcatcgtgcca aataccacatttcctgttggcacagtttcacagaagtaaacataagcatgttttaacagg tttttcttttcttttttcttttttaaaatgttttatttatttaacccgccattgtgtgtt tttaagtattttcttttnnnnnnnnnnnnnnnnnnnnnnnncaatctaactggctatgtt attattattaaatttatgttttgcaacttagaaaccagctacagtatgg

>34176_at HG-U95Av2 ggagcttattcctggctccatcgctaacacgttgactgcttattatgggaaanttttctc tgaagccagggagaagcattgattgatgtgggcaaatccaagctccagccaggtcgcagt cccaaatgccgacatcactgactccagggaccagggacatggagaaagctgtttatgata tctttaaccaggccctcttnactagagctggtgtttgtgactggnccaacaagatgtggc tatgnccaggggacatctgagtatgtgncccagtcatcttttttcacaggttgaagggag agaaaagattttgagttaaggtcattggctgctctactctgtcccctacctggtcaccta gtgatagccccagtggagatactgtccatacaaggtnnnnnnnnnnnnnnnataccacag taaaaggccaggccaggaggggtaggagac atggagatcttacctcctgataaatg

>34303_at HG-U95Av2 aatgtcaaccggagcccttacaccagccctccagcatctaatnnacttnnaanntnnnnt naannnannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nntggcagcggnct atccttctctgttgccaaccttgccgtccgacctcctccgccccc atgcggtgaccccgtccgtgtctgtgtctgtccatacgtgtgagtccagctaaaaagaca aaacagaaccnnnnnnnnnnnnnnnnnnnnnnnntggagaaggctccgacgtctccgaag tgcagcccttgggatggcattccgttgtgtgccttattcctggagaatctgtatacggct cgcctatagaaatatagcct

>34678_at HG-U95Av2 ccgaactatttgtcaatgaagattgtaaagccaaatgtgtaacaaaggcaaaggcttcat ttcaagagtcatccagcaatgagagaatcctgcctctgtagaccaacatccagtgtgatt ttgtgtctgagaccacaccccagtagcaggttacgccntgnnnncnnnnnncnnnnntnn nnnnnngnnnntnnnnnncnnnnnnnnnnnnnnnaacnnnnnnnnnnnnnnnnntgttat ctcttaagtattaaaagttttattttctaaagtttaaatcatgtttttcaaaatattttt caaggtggctggttccatttaaaaatcatctttttatatgtgtcttcggttctagacttc agcttttggaaattgc aaatagaattcaaaaatctctgcatcctgaggtgatatacttc atatttgtaatnnnnnnnnnnnnnnnnnnnnnnnaannnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnngcccacaaccattgctatattttgtatgga

>34800_at HG-U95Av2 tggccaaaagctgaagggagttactgagaaaatagttaacaattactgtcaggtgtcatc actgttcaaaaggtaagcacatttagaattttgttcttgacagttaactgactaatctta cttccacaaaatatgtgaatttgctgcttctgagaggcaatgtgaaagagggagtattac ttttatgtacaaagttatttatttatagaaattttggtacagtgtacattgaaaaccatg taaaatattgaagtgtctaacaaatggcattgaagtgtctttaataaaggttcatttata aatgtcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaannnngncnnnaattatc tttcccccaaaaaagaaaaaaaaaataggcgaagcaaaatcacatactgtttgttnnnnn nnnnnnnnnnnnnnntgctagattcctgacattttgttttgaatttttctacacctggag cttgt

>34857_at HG-U95Av2 gaaagctttcccaattgcacttgcatctaaacaaaactgttgcagtttttactctattta ttttgttccccatgtttatgaaagtcctgcacagtttcaaaggcatggtaaataatatat caatgtttatgtagtctgttacagaaacagctatagataacattatccagtgaagagcaa aattcaagctttagaaaatattcatgcatgcaattttgacatatctaaaaataggttttt gtatatttatggtgggaggtggttgggaacttttaacaaaatggggtgttaatttttgta cagtctgtgggcatttacacatttttaatgtattaaaatttggtaattatgtgtacatta aattaataaaagttacttctagttatgatttgtgaattccctaagaccttggattttttt aagtaactttatatcagaaatgatactgcatctttatatttttaaaattgtattgctgct caagaatggtaccctcttgtcaaaaaggcat

>35484_at HG-U95Av2 acactgttttgtaatgatcgctttgcatgtcttttccagctgactccgccaccatctcct gcctggatgactgcagcagcatccttgctggcctctctgcttcctgcattgcctcctctg aatcttcaggatgccaagtttgtggaggaacggagannnnnnnnnnnnnnnnnnnnnnnn anngtcatgaacaaagtcatccagatggtccccgagttcgctgccagccccnannangnn nnccnnnnncnnnnnnnngcccttcttcgtgatgggattacaggtcggaatgtacggatt gtttcattttggggtaatgatggatcagccacagccaagccttacccgtgctgacgaatc t

>35763_at HG-U95Av2 ttgcccatgaaggtggccatccgcagcgtggccgtgaccaaggagcgcagccacgtgctg gtgggcctggaggatggcaagctcatcgtggtggtcgcggggcagccctctgaggtgcgc agcagccagttcgcgcggaagctgtggcggtcctcgcggcgcatctcccaggtgtcctcg ggagagacggaatacaaccctactgaggcgcgcnnnnnnnnnnnnnnncggctgctcggg ccccgcccccggcaggcctggcccgggaggccccgcccagaagtcggcgggaacaccccg gggtgggcagcccangggggtgagcggggcccaccnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnccctcagggattggcgggcggaagtcccgcccctcgccggctgaggggccg ccctgagggccagcactggcgtctgcggccgctgnnnnnnnnnnnnnnnagtctggggnn gggttccccggcttccaagtcgctg

>35861_at HG-U95Av2 gatgctgcccttctttgcacgaaagcctggccctcttgctttggcgtgataaacccctgt ccatcttccccaaagctcatttatgagcccacccagaggctcctacccccaaagattttc acagaaacttgaggcc

>35959_at HG-U95Av2 ga cttcagaaagtaccataatgtcatcctactctacatttcacaagacgaattattttg agatttgtttattatattaaaatgtttttttacgttcccactaaattttgaccccatat aagaaatgtgttatgtatgttgtgcctccttagagacataaatttagtgtcaaaacatgg gagatggcttactcagaagcatac ccacttaacataccatggcctgagctaagtaccat gtcctgtttgtgtcttatttttaaatattttctttgtccacatgggccgttgaccttaga gttaaggcggttngcttttttgaagaaatcanccaaagtttctgggaaacta gttncaa ggttgaaatggagagtagatttaattttatttgtcttgtagggaagaaatcttcctttga accgcttttcttgctttttccctttttcccaaactaggttacaggttcttatctgcaagg ttcaagttgcttagacattgttttccagtattctgcagggccagtcagttgtacagaagt t

>36014_at HG-U95Av2 gttctaagcatgcagttctcacctccatttagtcccccatcagaacagnnnnnnnnnnnn nnnnnnnggagcctaaatttagttcagcttacctttgagaatagcatcaattcagactct cttttcattatgttttcttttctttttccctctttttaaactacattgtgttagagtcat agtctaggatcctgagagattttccattcttgtcaccattcacttgcattgtaaagattt tctttgtctgttgttggcatagattcttttgtacatatttatttatttgtgtttatatat gtcaattggtttcctttcttagcttgatattgcctagctttgttgttttaattaactttc tat agagagactgtatatattttttctaaatactttgtgaaatcatttttggtagcaat atctttgaatatgatgaataaaagtgactgtgagtgcaaatagaattagcagtaagaagc tac ctagctaatttgccat

>36250_at HG-U95Av2 gccccagacccttgaaggaaggtgctccccttcacacacccaggctggaaannnnnnnnn nnnnnngacggcttgatggtagccaggacctcctctttactgcgggggtgggcgggggcg gaggatgggaactggctagtgagccctgaaata

>36336_s_at HG-U95Av2 cccggagaggtgctggacctcacctacagccccccggccgaggccttcccgccgcccccg cacttctctttcccggcgccgctgtccctggacgccggccccggcgtcgtgccgctgggc acccccgacgcccaggccgaccctgcggccctcgcgcaccagggctgcgacatcaacttc aaggaggtgctggaggacatgctgcgctcgctgcacgcggggccgccctccgagggcgcg ctgggggagggcgcgggggcggggggcgcggcgggcggtggtcccgagcggcagagcgtg atccagttcagcccacc

>36497_at HG-U95Av2 attcacacggtactcagaggcactgntggggaagtttgttggtctttattagataaattt ccagagacctgtccataatacccaacagaacatgactgtttctttgaggaaagggttata atgtctgtggtgtacaagtcgtttttggtataacttctttcctgctgctgctgcttcccg gcaaacatagttttcctatttcaggcagagtgcggtatattccaggaaacactgtttcct actcacttagcttacttctttgttgaatgcctcactaatggcaagtttcaagatgttttg ggtgacaatgcacacatgctgggcaaaagggtgatggccagtggctggcagctgggccag cagaagctaggacatctgtgagttgtcattctcatctatccatgtccactggcctgccag catccgccagtgccttgccagtgtgcacggtcccacactgtggcccctgagtcccctaat gtacacgctgcagccagaatgcagatggagctggcttggctgttccctggatg

>37030_at HG-U95AV2 ccacgactgaagttgtagattgagcngaataaccatgggaagtgaccaagncaaagacac tcgattggnagtcagttgaatatttgtaccentcagtggagcccttctggntcttttctn nnnnnnnnnnnnnntttcctctagncaaatacttctttctccttgcttgcctccaccatg atatttgaataagagatggccagaggataacacttgtctcttaaaaactaagctaaaaag aacctagaaccttcaattgagcagttgtgaaaattgctaatggtnccaaggccaagcaaa gagtttcagaaaatgactgagaaggagcgataacccccagaatgcaaaatcaggggcatc attatccggtgcttgaacaangnngntccgctctacaactggtttttttaggacttgtga ggaacacagcaacggaaatccatccacaaaggatgcagtgccccaacttgt

>37216_at HG-U95Av2 accactgctcagaggagccctaggccctggccgcagtgccttcagcgcccgacccgggcc cccacctggtcagccnnnnnnnnnnnnnnnnnnnnnnnnnnnnggccggggcgtggcagg gccctctctgtgcctctcctcccaagtaggaaggggctccgggtggctgctctgggactg ggcacccacaagggctcagtgggcccaaacccttnnnnnnnnnnnnnnnnnnnnnnncca agagctagaaactcaggaaaccccaggtgctcagggccccgcgtctcgggggctccgtgg ggcagacccctgctaatata gcaattctccctcccccagcccttccctgacccctaagt tattgcccgctca

>37786_at HG-U95Av2 cgtccattactcaaggagacagcataacagatgcagaacaagtcatatttgaagaatgtt ttgtactaaacttcatttaattattcagtttttaaagggaaaaagggcgtganctcacac agtgagctgtttatttaaatatcattaaggagaaaaaaaaata ggtgagaagctcgctc ctttcaacttgtttggtactgacagctgatagaagctattttctaataataaacatccag tgtgtgaaagacaaaaaaaaannantgcaatactctttttttaatgataaaacctgtgaa gtttcccaaagcaggttttaaaaggaaaaaaaggaaaagcaaaaaggttgctgttctcac tcccatctcatttagtgcatgtcttaattcgggattagtaatgaattggaggatcattag acatttctaggaacc

>37788_at HG-U95Av2 catgaatcacatagagcagtggagttttanccaagtggtgtgtgtggtttttgtttttta ctatgcaaagatgggaaatgcacaaacttttcaaagactagtgtctgaagaactttacaa acaatacttgaaccctttctttaaagttatcccatcatgttttatagtcattgttgcttc cattgttagtttccattttcaagtgctttgtaattttttaagtgcactacctgaaatttt gtttgaaattaataaattcattcgtatcttgttggctgcctatgaatggagattcagtag tcattgtatgcatctttaagtcaaatgtgtattaaaactttcgttaacgtanaaaaaaaa aaannnannnnnnaannnnnnnnnnnnnncnnccttttctgtttcctcttgtagtgctga tta

>38393_at HG-U95Av2 cccaaggtgggacttggagaatattttgcnttggcatatgtttggtctgaatggtgtagt tgctggttccctagagaggaaaaggtggcnnggcccnnnnnnnnnnnnnnnnnnnnctta atttccagttgaaaccctagtagaattgtgaatgaaaacctcaaggttgagncccctctg ccaagcagcagagctagtagaaggggatgcaggggcaaagcactcagttgccaagcaagg aggagagatgtacgtgggctgtgtggcagtccccacaccctgccctggcttcttcaggtt atcgcaccactatggaatcctttgcagaatggtactcatataatggtttaaaacaacaca ttcataattgactctgtgcaggatgtcactcaatcagtttgggtttgcttt

>38510_at HG-U95Av2 gtcctcccatattggcaaagataaagcaattgacaaaaatggaattcttgttcaatactg gcaggagtgaaaattggtagaacctttntagaaggcnattnggcnannatgtatgnaaan cntaaatgtngatacncctttacccagcagtttgtttnggaatttatcctaatgaataaa agttgnccnagncntcnaaacangannnnnaannnanatttcnatgatgtttatgatatt aaaacattggnaacaactgaaacatccntcagtaaaagatggattaaataaattccatgc nagttgtcatttaaaaatatttagatatatgtttattgctatggatatatgttcccaaaa tattattgaatcaaaaagtagactacaggatatatgttgaatatgagctcatttataaca ttgaatattttaagataatgtatgtttcatagagagatcttcaccaaatgttaaggattt

>38717_at HG-U95Av2 tacaaggttgccacacctagttctgcccagctttatgtcttttattccagtattccacca aagtttgttttcctgncattccagttctcaagtcttaagnataaagattgtacttgacag tttagtatatccataaaactatttgaggtggttaaggttcttgggttcattttccttaat actttgctgaatattgtagattgtaggcaatgaaaaagtctactaaattaggaaaacctt gaataattaggta cctaggtaagagcccctaaacatcaagcaatctgtgagtctgtaaa gaaataaatattttttggattattcttatctaattccacccctgttggaagatgatttct ttgttctttgcaactatggaagctg

>38749_at HG-ϋ95Av2 ggcggcagcacagcacctgcacgaacacccgccgaaactgctgcgaggacaccgtgtaca ggagcgggttgatgaccgagctgaggtagaaaaacgtctccngagaaggggaggaggatc atgtacgcccggaagtaggacctcgtccagtcgtgcttgggtttgnccgcagccatgatc ctccgaatctggttgggcatccagcatacggccaatgtcacaacaatcagccctgggcag acacgagcaggagggagagacagagaaaagaaaaacacagcatgagaacacagtaaatna ataaaaccataaaatatttagcccctctgttctgtgcttactggccaggaaatggtacca atttttcagtgttggacttgacagcttcttttgccacaagcaagagagaatttaacactg tttcaaacccgggggagttggctgtgttaaagaaagaccattaaatgctttagacagtgt aaaaaaaaaaaaanannnnnnnnaannnnaaaaaaannnnnnnattggtgtttgtttgcg tatccngaaagcagntcatgtta ccataaatctggttttg

>38972_at HG-U95Av2 cgttagtaaccatttagtgacaaaggattaaaacatccatctggatgttaattttgaaga tgtaaattatatgttgtttaaatttttccaggcatctgaaaaccttatctgctagacaat gtaagattcacacagagttatctngggattctgattttttaaatagtacatatcattaaa ccattttctctaaatgtaagaagagcagaaaaaatcttataagattatcagatttttcta atgacacagaaatgtaagaaaaaaatccctttatattgaaaaaagatgcagtcaaagtct tttcagacatgcccaaactttgagaatttcttcaaccatctaatgctataaagatttttg ttcttcctgttcacaaccagttgtataacagaaatactagc actgttttccttcctgtg t

>39582_at HG-U95Av2 ggccacaaatggagggattgtcctttcaagcaccacagcttcagataaaattagtacttt caaatattgtccactttaacttaaaaaattctagaggga tatattggagactcaactgc ccttnggttttagtttataaaatggcctagtactgtggaattttaattttagaaagtctt agcatcagatcataaacattcattaaaagaactcacatcccatctgaaacttcccagggg agttgggattcttagtagattggtagaaaggggctcattttctactgcatttcccatttt tggtatcttgttcagcatgttttatttttatttcttgtctgcagaacatcctatatttat gagaacattctttaagaagaccaccacatagaataccccttcctatcagctcgctctgat ttagccttaat

>39597_at HG-U95Av2 caaacataacggatgtaaggcagaaagtgatcggagaaggaatgagaaantgtgcgtgat gttaatgaaaagtcatatgcagctagagcagacccaggaaagctttctggaagagattgc atctgaggaaattcaggaaggatctttgtagattggggggagattctaaattgaaggggt gatngggtgaggggccagagggaagtctgctgtgttctcatgtaggatgtcagccctccc tgcaacttctctttttggccaatgtcttttcactttcctgaccctttagaatcatcccca gccagacgcaatcatggaagttgccttattgtcactggttaagaacttggcgaga >39602_at HG-U95Av2 gggtctacattaatcttccagtactccttgctgatgctgtgttatgtgtcatctaacaga aatgactcctttgaaataagtaaatctttggctttttgttnnnnnnnnnnnnnnnnaagc aaaacaaacaaacaaaaacaaattttaagaacacaacaaaaaagatttgacttccgaa a gaatgttttctttaagaggcatgaaaagcaactattgttgtgttacagtgttaaaaatat tcagttnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnnnnntgtggcatctgaacttttataaaggtttccttgtgc caaataagtgcaaagatttaatttactattaaaaaccataagcatatgttatagttccag aagaattattttgtcatcaagtgattttgatctttagtgtcaatatttatatttagatta atttttataaatgaaaatattttaatggtttaagaaaatgaggacaacaggataatatct ttgatgacttctgaaagttatgcttccctt

>39827_at HG-U95Av2 acgtgctcctcagagcagccggagggaggggggaggtcggaggtcgtggaggtggtttgt gtatcttactggtctgaagggaccaagtgtgtttgttgtttgttttgtatcttgtttttc tgatcggagcannnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnannnnnnnnnnnaa nnnnagnnnnggnngggnnnnnngnnnnggatcacttgggatctttgacacttgaaaaat tacacctggcagctgcgtttaagccttcccccatcgtg actgcagagttgagctggcag gggaggggctgagagggtgggggctggaacccctccccggnnnnnnnnnnnnnnnnnnct tccatctagaactgtttacatgaagataagatactcactgttcatgaatacacttga gt tcaagta

>39837_s_at HG-U95Av2 cctagttctcacgaggaccctttcttgcccacagtttcgagaggcccgtgccatgagacc gcctggggtgagcaaggcgacctgnnctgctgccngaaggtttggccgccgcgggacacc tgtttccttcccncagtgtctgcgtccgcacagcatacccagctcggacctcctaggaca gagactcagcgaacccttgctgggaaccgctgagctgaagttcttggaaggctcccaccc aggtgccccgttggaaagcagatat

>40239_g_at HG-U95Av2 tataag atgcaacagtcagccgggggaagataaaggtacattataaaacacacattaat gcatttaataaata atattatctatcaaaagtgagccttagctcttcatcagttaataa aaagcacctgctgagaactcctgtaagctggtatcatcattgcatcattggattataaaa gccacaatgctccctttcaacttggggtttg

>40472_at HG-U95Av2 ttgctgaagagcaagcagagggtccnnnncgcctgctgtacaannnnnnnnnnnnnnnca tcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnaggcctctccctctgtcagttccagaacttctccctccatg acccactctatgggaaactcttcagcacctacctgcgccccccacacacctctcgaggca cctcccagacaccaaatgcctcatccccaggcaaccccactgctctggccaatgggactg tgcaagcacccaagcagaagggagactgagtgcctcagcctctcaccccctcctcctcag ggcagcgctaggggcctcccctatgcctcagccccatctctgctcctgtttgaattttg

>40642_at HG-U95Av2 taagcccttgatgacttattgcatgatacagtannnnnnnnnnnnnnnnnnntaaataca tgaaaagcagtgtaagctagtgacactaaagccagtcttgtattactgtatttttgacag aatggttttgaaaactgtgctacagggactgatgtggcaaatatatctctttatgcagaa ggaagtctttttttttcntttttttttttttaagaagtatggctttttatgcatcct ca tcgagggcattgaagttgcatggactgataaaagttgatgcaaaacaagaaagaaacaaa caaaaaaaaaaaaccagcaaaatgtttaccaaaaaactcaaacaaatgagcagtgcctgt tcaatttcacagtctctgttgagttcagttgtaaatatgtttcaaatgacattttcttgg gaaaaaaaatctctacaacattgtagaatgtgaggggtaactacatcccaggcatag

>40855_at HG-U95Av2 ctcatgtatttatgcctaatgtaagctgacttttaaaaagctttcttttgttgcatgccc tgtgcaggcatctgtattgtacatgcatgcctttcgtcctgttttcctgtataaagttag tgaacaaagaaatatttttgcctagttcatgttgccaagcaatgcatattttttaaattt gtcatatatggaaagagcatgtttgttacatgtaaaagctttactgatatacagatatac taatgtttgaagatgctgttctttgcaagtgtacagttttcannnnnnnnnnnnnnnnnn ncacccttgtggtttaaacttgctacaatgtatttattattcatttcctcccatgtaact aagaatcatggctat

>41229_at HG-U95Av2 caacttttgtaggactgtgtgtttctttagatacatttagtacaactgtaggtgacgagt agtcagttattgcttgctagctacnnnnnnnnnnnnnnnnnnnnnnnnacttttggcatt ttgtcctcatgggccataaatacagaaccttgtattttaattaaanttttttncaaaagg anggnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnttagcagtaggatgtattatacgaca gttacttaatttctagagttcaggcctctgggatcaaccccagactgggccagaatgtta gtgaaggttttattgtgcccggttggaggataacgttctttgggtactttttgtgggttg caaatgaactcaattgccacaagttttaaactggtgtaaatcaagcttgacttaatgtga ttgttactgttatatccagcctatactgctagcagctgctcatactgcagtcaattactg gaagcggatat

>41690_at HG-U95Av2 ttgccctggtgagacccataccattnnnnnnnnnnnnnnnnnnncttaaagtccagtgtt ggctgttagtgtat tgatattctgcctgtctcctcatggttgaaatatgtctgaagaat agcagcataatctcttggctgtttatacttttttaaactttcctgtgttgtaaatattgt atacttttggtgattccagctatgtaacctctatgctctgtaaggtgattat tgtatat agcaacatggcccagtgatattat tagtttcccaatggagaggttattgagtaaccttt gcattagtttaaacactaccagaagaatgctgagccaactataaacactcaattttgtat gttttccaaattgtacttattactgcttttgatactgtattacgtgccaatagtttccca atcacatagcaggcaaga

>41710_at HG-U95Av2 ccataattgtttagccatgtgagtttcaggttggtacacgttcagacagaactgctgtat cacattccaattttgaatagccagtgagcaatcaagtgtagagaaatgataaatggcct agaagnnnnnnnnnnnnnnnnnnnnatgctcttcctagtagcttaataggccacaagcta gtttctgttgcactctgaaataaaatatgctttaaaaatgtagggaacagtgcttagaaa agcaaaaactaggtgtgtcattgaaataataggcataaaaattaaatgttacataagaac actatttggaaagagggtccttttaaaaactgaatttgtactaaatcagatttgccatgt ccagtacagaataatttgtacttagtatttgcagcagggtttgtctttgtgaattc

>41735_at HG-U95Av2 gctctacactccagggcatcttgacccagccgaaaaagttgaagatgctcaccccaagtt atggtgtgcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn nnnnnnnnnnnnnnnnnnnnncactgcaaaagtgaactgcatggtgatggccgaccagaa ccaggtgtgggttggctcggaagactccgtcatctacatcatcaacgtccacagcatgtc ctgcaacaagcagctcacagcccac gctccagtgtcacggatttgattgtgcaggacgg acaggaggcacccagcaacgtgtactcgtgcagcatggacggcatggtgctggtgtggaa tgtgagcacactgcaggtgacca

>41837_at HG-U95Av2 tcaccaatgcatatgaagagtatgcttggggaagagcttaggaatggggtgggcatggga ntgctgggtagncagccnnttnnagcaaatctgcatcnntnctcttatttcnnngacctt tntnccangtnncccagtccnnntnnnnnnnnnnnnnnnnnnnnnnnnnnnntnctttat ac atttaatcttttgcagaaaccttactattataacttgctactctccagataccaatt cttcnnnnnnnnnnnnnnnnnnnnnnnnnnntgtcttactga gtttteatgatcaactt gtaaatgtaagcagttgacttcataaaaggtattttaactattcttggagtcctttgcta cccaagcacctggtttcaccatgcgatcactgacttctctacag

>717_at HG-U95Av2 gttcggatttgactgcctgtatatgttttgtgaaatggtcctgtttttgggtaggtgaca cgtggactctagtatgtaaatgttacttgaatctgtgcttcataatagtgtgtggcatgt atgtgcagactcttggatgctttatgcctgcgcaccaggagccctgtcctcacgttccca ggagggcggcttcacccttcgtaaccaggagacaaggcggccatggatttgcccttgatt ctattttgctaatggaagatagaaaggagagaaggtttttttttttttttaacattctga agatggtgctgtgtcaagaaggaccttttttttcccctctcccctattttttaagtacct tggaggaggagaggttggtgacatgcatggtggggatctatggcctctggtgctt

Claims

Claims :

1. A method of assessing a tissue inflammatory response comprising: making a quantitative determination of the level of at least five transcripts shown in Table 1, or proteins encoded thereby, in a sample; and comparing the abundance of said transcripts or proteins so determined with the level of said transcript obtained from a control sample.

2. The method according to claim 1 wherein said sample comprises cells obtained from a site within a patient believed to be affected by a tissue inflammatory response.

3. The method according to claim 2 wherein the cells are endothelial cells or said sample is of patient blood, serum or urine.

4. The method of claim 3 wherein the endothelial cells are human umbilical vein endothelial cells, human coronary artery endothelial cells or human uterine microvascular endothelial cells.

5. The method according to any one of claims 1 to 4, wherein the control sample is obtained from endothelial cells from a tissue of said patient not affected by a tissue inflammatory response.

6. The method of any one of claims 1 to 4, wherein the control sample is obtained from a tissue demonstrating an inflammatory response in said patient at an earlier point in time.

7. The method of any one of claims 1 to 6 wherein the tissue inflammatory response involves one or more of: the movement of leucocyt Ies across an endothelium, the movement of leucocytes to inflamed tissue, the activation of leucocytes, the activation and angiogenesis of endothelial cells and/or the inhibition of apoptosis of leucocytes or endothelial cells .

8. The method according to claim 1 which is a method of diagnosing a condition with which a tissue inflammatory response is associated or monitoring the progress of a condition with which a tissue inflammatory response is associated and which is already diagnosed or monitoring the effectiveness of treatment of a condition with which a tissue inflammatory response is associated.

9. The method of any one of the preceding claims, wherein said determination is made after a course of treatment of said patient.

10. The method of any one of the preceding claims, wherein the abundance of at least 10 transcripts or proteins encoded thereby shown in Table 1 is determined.

11. The method of claim 10, wherein the abundance of at least 20 transcripts or proteins encoded thereby shown in Table 1 is determined.

12. The method of any one of the preceding claims, wherein the abundance is determined by hybridisation to a gene chip array.

13. The method of any one of claims 1-11, wherein the abundance is determined by quantitative PCR.

14. A method for the diagnosis of a condition with which a tissue inflammatory response is associated comprising the determination of the abundance of endothelial cell-derived proteins encoded by at least five of the transcripts of Table 1 in a sample from a patient suspected of suffering from such a condition.

15. The method of any of the preceding claims, wherein the tissue inflammatory response is associated with an inflammatory disease, vasculitic syndrome, atherosclerosis or an associated disease, chronic transplant rejection or wherein the condition involves tumour growth.

16. The method of claim 15 wherein the inflammatory disease includes inflammatory bowel disorders, psoriasis, ischemic reperfusion, adult respiratory distress syndrome, asthma, allergic rhinitis, dermatitis, meningitis, encephalitis, uveitis, diseases involving leucocyte diapedesis, central nervous system inflammatory disorders, Alzheimer's, endometriosis, multiple sclerosis, multiple organ injury syndrome, alcoholic hepatitis, bacterial pneumonia, antigen- antibody complex mediated diseases; inflammation of the lung (including pleurisy, alveolitis, pneumonia, chronic bronchitis, bronchiectasis, cystic fibrosis and COPD) , vasculitis, polyarteritis nodosa, giant cell arteritis, microscopic polyarteritis, pre-eclampsia and autoimmune diseases .

17. The method of any of the preceding claims, wherein said comparison determines an alteration in the pattern of transcript levels or transcript abundance between said sample and said control sample.

18. The method of any of the preceding claims wherein the level/abundance determined is of at least one transcript or protein encoded thereby selected from: colony stimulating factor 3 (granulocyte) , colony stimulating factor 2 (granulocyte-macrophage), granulocyte chemotactic protein 2, diubiquitin, ELAM-1, TNF-induced protein 6, Exodus 1, IL-lβ, VCAM-1, ICAM-1, IAP1, TNF-inducible A20, RIPK2, MMP 10, TRAF1, JAK binding protein, dual specificity phosphatase 4, IL-6, IL- 8, Gro-gam a, MCP-1, Gro-beta, Gro-alpha, ENA-78, fractalkine, small inducible cytokine subfamily A14, small inducible cytokine A5, LI7 receptor, toll/interleukin 1 receptor-like 4, CCAAT, MAD-3, COX-2, Mn SOD, NO synthase, L-kynurenine hydrolase, tissue factor pathway inhibitor 2, laminin gamma 2, Toll-like receptor 2, natural killer cell transcript 4, TNF- alpha induced protein 2, cationic amino acid transporter 2A, fatty acid binding protein 4, TNF receptor superfamily member lib and TNF superfamily member 9.

19. The method of claim 18, wherein the transcript or protein encoded thereby is selected from: colony stimulating factor 3 (granulocyte) , colony stimulating factor 2 (granulocyte- macrophage) , granulocyte chemotactic protein 2, diubiquitin, ELAM-1, TNF-induced protein 6, Exodus 1 and IL-lβ.

20. A gene chip array suitable for use in the method of any one of claims 1 to 19, comprising at least five nucleic acids suitable for detection of at least five transcripts shown in Table 1; optionally a control specific for said transcripts; and optionally at least one control for the gene chip.

21. A gene chip array for detection of at least five transcripts shown in Table 1 comprising at least five nucleic acids selected from Table 2 capable of detecting the presene of said at least five transcripts; optionally a control specific for said transcripts and optionally at least one control for said gene chip.

22. A protein based assay suitable for use in the method of any one claims 1 to 19, for the assessment of at least five proteins encoded by transcripts including those shown in Table 1, optionally a control specific for said proteins and optionally at least one control for the assay.

23. An assay according to claim 22 which is an ELISA or antibody chip.

24. An assay method for determining a modulator of a tissue inflammatory response or a condition associated therewith comprising: a) providing a protein encoded by transcripts from Table 1; b) bringing the protein into contact with a candidate modulator of its activity; c) determining whether said candidate modulator is capable of modulating the activity of the protein.

25. An assay method according to claim 24, wherein said candidate modulator is an antibody or binding fragment thereof which binds said protein.

26. An assay method according to claim 24, wherein said candidate modulator is a fragment of said protein or a mimetic thereof.

27. An assay method for a modulator of a tissue inflammatory response or a condition associated therewith, wherein said method comprises a) providing an endothelial cell in culture; b) bringing said cell into contact with a candidate modulator of said condition; and c) determining whether said candidate modulator is capable of modulating the level of at least one transcript of Table 1.

28. An assay method according to claim 27 wherein said candidate modulator is an antisense oligonucleotide or an RNAi.

29. An assay method according to claim 27 wherein said candidate modulator is a sense oligonucleotide.

30. Use of a modulator obtained according to the assay methods of any one of claims 24 to 29, for the treatment of a tissue inflammatory response or condition associated therewith.

31. A vector comprising a sequence encoding a transcript from Table lb operably linked to a promoter for transcription of said sequence.

32. The vector of claim 31 wherein said sequence is linked in frame to a translation initiation region for translation of said sequence.

33. The vector of claim 31 wherein said sequence is in an antisense orientation.