EP1701936A4 - Procede efficace de production de forme a polymorphe de (e)-entacapone - Google Patents

Procede efficace de production de forme a polymorphe de (e)-entacapone

Info

Publication number
EP1701936A4
EP1701936A4 EP03819304A EP03819304A EP1701936A4 EP 1701936 A4 EP1701936 A4 EP 1701936A4 EP 03819304 A EP03819304 A EP 03819304A EP 03819304 A EP03819304 A EP 03819304A EP 1701936 A4 EP1701936 A4 EP 1701936A4
Authority
EP
European Patent Office
Prior art keywords
entacapone
manufacture
polymorphic form
efficient process
efficient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03819304A
Other languages
German (de)
English (en)
Other versions
EP1701936A1 (fr
Inventor
Mukarram Siddiqui Moham Jaweed
Rashid Abdul Rehman Khan
Ram Prasad Yavad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Ltd
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Publication of EP1701936A1 publication Critical patent/EP1701936A1/fr
Publication of EP1701936A4 publication Critical patent/EP1701936A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
EP03819304A 2003-12-24 2003-12-24 Procede efficace de production de forme a polymorphe de (e)-entacapone Withdrawn EP1701936A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2003/006176 WO2005070881A1 (fr) 2003-12-24 2003-12-24 Procede efficace de production de forme a polymorphe de (e)-entacapone

Publications (2)

Publication Number Publication Date
EP1701936A1 EP1701936A1 (fr) 2006-09-20
EP1701936A4 true EP1701936A4 (fr) 2007-01-24

Family

ID=34803655

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03819304A Withdrawn EP1701936A4 (fr) 2003-12-24 2003-12-24 Procede efficace de production de forme a polymorphe de (e)-entacapone

Country Status (4)

Country Link
US (1) US20070004935A1 (fr)
EP (1) EP1701936A4 (fr)
AU (1) AU2003296838A1 (fr)
WO (1) WO2005070881A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1945607B1 (fr) * 2005-11-09 2009-10-14 USV Limited Procédé pour la préparation de (e)-n,n-diéthyl-2-cyano-3-(3,4-dihydroxy-5-nitrophényl)acrylamide (entacapone) extrêmement pur
US20080300420A1 (en) * 2006-01-02 2008-12-04 Sanmar Speciality Chemicals Ltd. Process for the Preparation of Entacapone Form-A
US7932415B2 (en) * 2006-02-06 2011-04-26 Orion Corporation Process for manufacturing entacapone
WO2007094007A1 (fr) * 2006-02-13 2007-08-23 Suven Life Sciences Ltd., Procede ameliore de preparation de l'entacapone
WO2007113845A1 (fr) * 2006-04-03 2007-10-11 Alembic Limited Procédé de préparation de (e)-2-cyano-3-(3, 4-dihydroxy-5-nitrophényl)-n, n-diéthyl-2-propénamide (entacapone)
GB0613826D0 (en) * 2006-07-12 2006-08-23 Pliva Istrazivanje I Razvoj D Process and product
WO2008023380A1 (fr) * 2006-08-24 2008-02-28 Srinivasa Reddy Battula PROCÉDé AMÉLioré ET SIMPLIFIÉ POUR LA PRÉPARATION DU (E) N,N-DIÉTHYL-2-CYANO-3-(3,4-DIHYDROXY-5-NITROPHéNYL)ACRYLAMiDE
ES2319024B1 (es) * 2007-02-13 2009-12-11 Quimica Sintetica, S.A. Procedimiento para la obtencion de entacapona sustancialmente libre de isomero z, sus intermedios de sintesis y nueva forma cristalina.
WO2009084031A2 (fr) * 2007-12-03 2009-07-09 Neuland Laboratories Ltd Procédé amélioré de préparation de la forme polymorphe a du (2e)-2-cyano-3-(3,4-dihydroxy-5-nitrophényl)-n,n-diéthyl-2-propènamide
CN105061259A (zh) * 2015-08-25 2015-11-18 重庆植恩药业有限公司 一种恩他卡朋a型晶的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0426468A2 (fr) * 1989-11-03 1991-05-08 Orion-Yhtymä Oy Forme polymorphe stable de (E)-N,N-diéthyl-2-cyano-3-(3,4-dihydroxy-5-nitrophényl) acrylamide et procédé pour sa préparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
YU213587A (en) * 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0426468A2 (fr) * 1989-11-03 1991-05-08 Orion-Yhtymä Oy Forme polymorphe stable de (E)-N,N-diéthyl-2-cyano-3-(3,4-dihydroxy-5-nitrophényl) acrylamide et procédé pour sa préparation

Also Published As

Publication number Publication date
WO2005070881A1 (fr) 2005-08-04
EP1701936A1 (fr) 2006-09-20
AU2003296838A1 (en) 2005-08-11
US20070004935A1 (en) 2007-01-04

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