EP1605931A4 - Preparations medicamenteuses contenant des triglycerides a longue chaine et a chaine moyenne - Google Patents

Preparations medicamenteuses contenant des triglycerides a longue chaine et a chaine moyenne

Info

Publication number
EP1605931A4
EP1605931A4 EP03816401A EP03816401A EP1605931A4 EP 1605931 A4 EP1605931 A4 EP 1605931A4 EP 03816401 A EP03816401 A EP 03816401A EP 03816401 A EP03816401 A EP 03816401A EP 1605931 A4 EP1605931 A4 EP 1605931A4
Authority
EP
European Patent Office
Prior art keywords
long
medium chain
chain triglycerides
drug formulations
formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03816401A
Other languages
German (de)
English (en)
Other versions
EP1605931A1 (fr
Inventor
Edgar H Ulm
Robert Mansfield
Marcus Boehm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Conforma Therapeutics Corp
Original Assignee
Conforma Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2003/010533 external-priority patent/WO2003086381A1/fr
Application filed by Conforma Therapeutics Corp filed Critical Conforma Therapeutics Corp
Publication of EP1605931A1 publication Critical patent/EP1605931A1/fr
Publication of EP1605931A4 publication Critical patent/EP1605931A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP03816401A 2003-03-13 2003-10-04 Preparations medicamenteuses contenant des triglycerides a longue chaine et a chaine moyenne Withdrawn EP1605931A4 (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US45481203P 2003-03-13 2003-03-13
US454812P 2003-03-13
PCT/US2003/010533 WO2003086381A1 (fr) 2002-04-10 2003-04-04 Formulations d'ansamycine et procedes de production et d'utilisation de celles-ci
WOPCT/US03/10533 2003-04-04
US47843003P 2003-06-12 2003-06-12
US478430P 2003-06-12
US49105003P 2003-07-29 2003-07-29
US491050P 2003-07-29
PCT/US2003/031667 WO2004082676A1 (fr) 2003-03-13 2003-10-04 Preparations medicamenteuses contenant des triglycerides a longue chaine et a chaine moyenne

Publications (2)

Publication Number Publication Date
EP1605931A1 EP1605931A1 (fr) 2005-12-21
EP1605931A4 true EP1605931A4 (fr) 2009-04-29

Family

ID=35351739

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03816401A Withdrawn EP1605931A4 (fr) 2003-03-13 2003-10-04 Preparations medicamenteuses contenant des triglycerides a longue chaine et a chaine moyenne

Country Status (6)

Country Link
EP (1) EP1605931A4 (fr)
JP (1) JP2006514994A (fr)
CN (1) CN101756961A (fr)
AU (1) AU2003277299B2 (fr)
CA (1) CA2518836A1 (fr)
WO (1) WO2004082676A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004309395C1 (en) 2003-12-23 2012-10-04 Infinity Discovery, Inc. Analogs of benzoquinone-containing ansamycins for the treatment of cancer
ME01498B (me) 2004-11-18 2014-04-20 Synta Pharmaceuticals Corp Jedinjenja triazola koja modulišu aktivnost hsp90
CA2596867A1 (fr) * 2005-02-28 2006-09-08 Kosan Biosciences Incorporated Preparations pharmaceutiques contenant 17-allylamino-17-demethoxygeldanamycine
WO2006110473A2 (fr) * 2005-04-07 2006-10-19 Conforma Therapeutics Corporation Formulations pharmaceutiques a base de phospholipides et leurs procedes de production et d'utilisation.
US7691392B2 (en) 2005-04-29 2010-04-06 Kosan Biosciences Incorporated Method of treating multiple myeloma using 17-AAG or 17-AG or a prodrug of either
WO2007094819A2 (fr) 2005-08-18 2007-08-23 Synta Pharmaceuticals Corp. Dérivés de triazole modulant l'activité de hsp90
EP1954265A2 (fr) * 2005-12-01 2008-08-13 Conforma Therapeutics Corporation Compositions contenant de l'ansamycine
PE20081506A1 (es) 2006-12-12 2008-12-09 Infinity Discovery Inc Formulaciones de ansamicina
JP5583680B2 (ja) 2008-10-15 2014-09-03 インフィニティー ファーマスーティカルズ インコーポレイテッド アンサマイシンヒドロキノン組成物
SG10201407538WA (en) * 2009-08-14 2015-01-29 Opko Health Inc Intravenous formulations of neurokinin-1 antagonists
US9205086B2 (en) 2010-04-19 2015-12-08 Synta Pharmaceuticals Corp. Cancer therapy using a combination of a Hsp90 inhibitory compounds and a EGFR inhibitor
WO2013067165A1 (fr) 2011-11-02 2013-05-10 Synta Pharmaceuticals Corp. Polythérapie d'inhibiteurs de hsp 90 avec des agents contenant du platine
AU2012332421A1 (en) 2011-11-02 2014-06-05 Synta Pharmaceuticals Corp. Cancer therapy using a combination of Hsp90 inhibitors with topoisomerase I inhibitors
WO2013074594A1 (fr) 2011-11-14 2013-05-23 Synta Pharmaceuticals Corp. Association thérapeutique d'inhibiteurs de hsp90 et d'inhibiteurs de braf
CN106018611B (zh) * 2016-06-21 2018-08-24 广州白云山汉方现代药业有限公司 一种气相色谱内标法检测中链甘油三酯含量的测定方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003086381A1 (fr) * 2002-04-10 2003-10-23 Conforma Therapeutics Corporation Formulations d'ansamycine et procedes de production et d'utilisation de celles-ci

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2166320A1 (fr) * 1993-06-29 1995-01-12 Randall James Gallaschun Derives d'ansamycine, agents antioncogenes et anticancers
US5932566A (en) * 1994-06-16 1999-08-03 Pfizer Inc. Ansamycin derivatives as antioncogene and anticancer agents
US6140374A (en) * 1998-10-23 2000-10-31 Abbott Laboratories Propofol composition
DE10036871A1 (de) * 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003086381A1 (fr) * 2002-04-10 2003-10-23 Conforma Therapeutics Corporation Formulations d'ansamycine et procedes de production et d'utilisation de celles-ci

Also Published As

Publication number Publication date
CA2518836A1 (fr) 2004-09-30
JP2006514994A (ja) 2006-05-18
WO2004082676A1 (fr) 2004-09-30
AU2003277299B2 (en) 2009-12-10
CN101756961A (zh) 2010-06-30
EP1605931A1 (fr) 2005-12-21
AU2003277299A1 (en) 2004-10-11

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20051004

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
RIN1 Information on inventor provided before grant (corrected)

Inventor name: BOEHM, MARCUS

Inventor name: MANSFIELD, ROBERT

Inventor name: ULM, EDGAR, H.

A4 Supplementary search report drawn up and despatched

Effective date: 20090401

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 9/00 20060101ALI20090326BHEP

Ipc: A61K 47/14 20060101ALI20090326BHEP

Ipc: A61K 9/19 20060101ALI20090326BHEP

Ipc: A61K 9/107 20060101ALI20090326BHEP

Ipc: A61K 31/395 20060101ALI20090326BHEP

Ipc: A61K 31/00 20060101ALI20090326BHEP

Ipc: A61K 31/33 20060101AFI20041006BHEP

17Q First examination report despatched

Effective date: 20090708

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20100921