EP1599189A4 - Formulierung mit gesteuerter freisetzung und mit wasserabweisendem material als mittel für die verzögerte freisetzung - Google Patents

Formulierung mit gesteuerter freisetzung und mit wasserabweisendem material als mittel für die verzögerte freisetzung

Info

Publication number
EP1599189A4
EP1599189A4 EP03816186A EP03816186A EP1599189A4 EP 1599189 A4 EP1599189 A4 EP 1599189A4 EP 03816186 A EP03816186 A EP 03816186A EP 03816186 A EP03816186 A EP 03816186A EP 1599189 A4 EP1599189 A4 EP 1599189A4
Authority
EP
European Patent Office
Prior art keywords
hydrophobic material
formulation containing
release agent
sustained release
release formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03816186A
Other languages
English (en)
French (fr)
Other versions
EP1599189A1 (de
Inventor
Mulye Nirmal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nostrum Pharmaceuticals Inc
Original Assignee
Nostrum Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nostrum Pharmaceuticals Inc filed Critical Nostrum Pharmaceuticals Inc
Publication of EP1599189A1 publication Critical patent/EP1599189A1/de
Publication of EP1599189A4 publication Critical patent/EP1599189A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP03816186A 2003-03-04 2003-03-04 Formulierung mit gesteuerter freisetzung und mit wasserabweisendem material als mittel für die verzögerte freisetzung Withdrawn EP1599189A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/006505 WO2004078164A1 (en) 2003-03-04 2003-03-04 Control release formulation containing a hydrophobic material as the sustained release agent

Publications (2)

Publication Number Publication Date
EP1599189A1 EP1599189A1 (de) 2005-11-30
EP1599189A4 true EP1599189A4 (de) 2009-07-01

Family

ID=32961106

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03816186A Withdrawn EP1599189A4 (de) 2003-03-04 2003-03-04 Formulierung mit gesteuerter freisetzung und mit wasserabweisendem material als mittel für die verzögerte freisetzung

Country Status (8)

Country Link
EP (1) EP1599189A4 (de)
JP (1) JP2006514672A (de)
AU (1) AU2003225649C1 (de)
BR (1) BR0318167A (de)
CA (1) CA2518442A1 (de)
MX (1) MXPA05009469A (de)
NZ (1) NZ542176A (de)
WO (1) WO2004078164A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005049001A1 (de) * 2005-10-11 2007-04-12 Basf Ag Verfahren zur Herstellung von direkttablettierbaren Ibuprofen-Formulierungen
JP2011500688A (ja) * 2007-10-18 2011-01-06 デュレクト コーポレーション 制御された嵩密度を有する生分解性インプラント
CN105456217A (zh) * 2014-08-27 2016-04-06 捷思英达医药技术（上海）有限公司 一种双丙戊酸钠缓释剂组合物及其制备方法
WO2017163267A1 (en) * 2016-03-23 2017-09-28 Sun Pharmaceutical Industries Ltd. An improved method of administering divalproex

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3343253A1 (de) * 1983-08-11 1985-02-21 Neill Bailey San Antonio Tex. Walsdorf Fluorid-tablette mit verzoegerter wirkstoff-freigabe und verfahren zu ihrer herstellung
WO1997032584A1 (fr) * 1996-03-04 1997-09-12 Synthelabo Formulations pharmaceutiques a liberation prolongee contenant de la mizolastine
WO2000001416A1 (en) * 1998-07-07 2000-01-13 Yissum Research Developing Company Of The Hebrew University Of Jerusalem Pharmaceutical compositions containing low-melting waxes
US6033685A (en) * 1997-01-10 2000-03-07 Abbott Laboratories Tablet for the controlled release of active agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL109770A0 (en) * 1993-05-29 1994-11-28 Smithkline Beecham Corp Thermal infusion process for preparing controlled release solid dosage forms of medicaments for oral administration and controlled release solid dosage forms of medicaments prepared thereby
DE19847618A1 (de) * 1998-10-15 2000-04-20 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
US6413546B1 (en) * 1999-03-18 2002-07-02 Indena, S.P.A. Tablets incorporating isoflavone plant extracts and methods of manufacturing them
AR025609A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones lipidas solidas

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3343253A1 (de) * 1983-08-11 1985-02-21 Neill Bailey San Antonio Tex. Walsdorf Fluorid-tablette mit verzoegerter wirkstoff-freigabe und verfahren zu ihrer herstellung
WO1997032584A1 (fr) * 1996-03-04 1997-09-12 Synthelabo Formulations pharmaceutiques a liberation prolongee contenant de la mizolastine
US6033685A (en) * 1997-01-10 2000-03-07 Abbott Laboratories Tablet for the controlled release of active agents
WO2000001416A1 (en) * 1998-07-07 2000-01-13 Yissum Research Developing Company Of The Hebrew University Of Jerusalem Pharmaceutical compositions containing low-melting waxes

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DAKKURI-A. BUTLER-L-D. DELUCA-P-P.: "Sustained release from inert wax matrixes III: effect of povidone on tripelennamine hydrochloride release", JOURNAL OR PHARMACEUTICAL SCIENCES, vol. 67, no. 3, 1978, pages 357 - 360, XP009117092 *
See also references of WO2004078164A1 *

Also Published As

Publication number Publication date
WO2004078164A1 (en) 2004-09-16
AU2003225649C1 (en) 2009-10-22
AU2003225649B2 (en) 2009-03-12
CA2518442A1 (en) 2004-09-16
MXPA05009469A (es) 2005-12-12
BR0318167A (pt) 2006-02-21
JP2006514672A (ja) 2006-05-11
AU2003225649A1 (en) 2004-09-28
EP1599189A1 (de) 2005-11-30
NZ542176A (en) 2007-12-21

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20050905

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AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20090602

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 31/19 20060101ALI20090526BHEP

Ipc: A61K 31/52 20060101ALI20090526BHEP

Ipc: A61K 31/7048 20060101ALI20090526BHEP

Ipc: A61K 33/26 20060101ALI20090526BHEP

Ipc: A61K 9/22 20060101AFI20040922BHEP

17Q First examination report despatched

Effective date: 20091119

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Effective date: 20111001