EP1578945A4 - Cct6s as modifiers of the rb pathway and methods of use - Google Patents

Cct6s as modifiers of the rb pathway and methods of use

Info

Publication number
EP1578945A4
EP1578945A4 EP03789986A EP03789986A EP1578945A4 EP 1578945 A4 EP1578945 A4 EP 1578945A4 EP 03789986 A EP03789986 A EP 03789986A EP 03789986 A EP03789986 A EP 03789986A EP 1578945 A4 EP1578945 A4 EP 1578945A4
Authority
EP
European Patent Office
Prior art keywords
cct6s
modifiers
pathway
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03789986A
Other languages
German (de)
French (fr)
Other versions
EP1578945A3 (en
EP1578945A2 (en
Inventor
Albert K Tai
Chunyan Song
Michael Martin Ollmann
Lucile A Gillett
Kim Lickteig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exelixis Inc
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of EP1578945A3 publication Critical patent/EP1578945A3/en
Publication of EP1578945A2 publication Critical patent/EP1578945A2/en
Publication of EP1578945A4 publication Critical patent/EP1578945A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
EP03789986A 2002-11-25 2003-11-24 Cct6s as modifiers of the rb pathway and methods of use Withdrawn EP1578945A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42887202P 2002-11-25 2002-11-25
US428872P 2002-11-25
PCT/US2003/037548 WO2004048541A2 (en) 2002-11-25 2003-11-24 Cct6s as modifiers of the rb pathway and methods of use

Publications (3)

Publication Number Publication Date
EP1578945A3 EP1578945A3 (en) 2005-08-18
EP1578945A2 EP1578945A2 (en) 2005-09-28
EP1578945A4 true EP1578945A4 (en) 2006-09-27

Family

ID=32393472

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03789986A Withdrawn EP1578945A4 (en) 2002-11-25 2003-11-24 Cct6s as modifiers of the rb pathway and methods of use

Country Status (5)

Country Link
EP (1) EP1578945A4 (en)
JP (1) JP4646631B2 (en)
AU (2) AU2003294499A1 (en)
CA (1) CA2506686A1 (en)
WO (2) WO2004048541A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263403B2 (en) 2007-04-23 2012-09-11 Stowers Institute For Medical Research Methods and compositions for stem cell self-renewal

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997041433A1 (en) * 1996-04-29 1997-11-06 Cancer Research Campaign Technology Limited METHOD AND MEANS FOR DISRUPTION OF p53 AND RB INTERACTION
WO1999041376A2 (en) * 1998-02-12 1999-08-19 Curagen Corporation Retinoblastoma protein complexes and retinoblastoma interacting proteins
US6071715A (en) * 1993-08-12 2000-06-06 Board Of Regents, The University Of Texas System Nucleic acids encoding novel proteins which bind to retinoblastoma protein

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071715A (en) * 1993-08-12 2000-06-06 Board Of Regents, The University Of Texas System Nucleic acids encoding novel proteins which bind to retinoblastoma protein
WO1997041433A1 (en) * 1996-04-29 1997-11-06 Cancer Research Campaign Technology Limited METHOD AND MEANS FOR DISRUPTION OF p53 AND RB INTERACTION
WO1999041376A2 (en) * 1998-02-12 1999-08-19 Curagen Corporation Retinoblastoma protein complexes and retinoblastoma interacting proteins

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DECAPRIO ET AL: "The Product of the Retinoblastoma Susceptibility Gene Has Properties of a Cell Cycle Regulatory Element", CELL, vol. 58, pages 1085 - 1095, XP008087857 *
FELDMAN DOUGLAS E ET AL: "Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC", MOLECULAR CELL, vol. 4, no. 6, December 1999 (1999-12-01), pages 1051 - 1061, XP002394305, ISSN: 1097-2765 *
KUBOTA HIROSHI ET AL: "Structures and co-regulated expression of the genes encoding mouse cytosolic chaperonin CCT subunits", EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 262, no. 2, June 1999 (1999-06-01), pages 492 - 500, XP002394304, ISSN: 0014-2956 *
LI WEN-ZHUO ET AL: "Tcp20, a subunit of the eukaryotic TRiC chaperonin from humans and yeast", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 28, 1994, pages 18616 - 18622, XP002394303, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
CA2506686A1 (en) 2004-06-10
WO2004048541A2 (en) 2004-06-10
JP2006507005A (en) 2006-03-02
AU2003294499A1 (en) 2004-06-18
AU2003294499A8 (en) 2004-06-18
WO2004048541A3 (en) 2005-08-18
JP4646631B2 (en) 2011-03-09
WO2004048536A3 (en) 2004-08-19
AU2003294501A1 (en) 2004-06-18
WO2004048536A2 (en) 2004-06-10
AU2003294501B2 (en) 2010-05-13
EP1578945A2 (en) 2005-09-28

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Ipc: 7A 01N 61/00 B

Ipc: 7C 12Q 1/68 B

Ipc: 7G 01N 33/53 B

Ipc: 7G 01N 33/48 A

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 49/00 20060101ALI20060817BHEP

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: LICKTEIG, KIM

Inventor name: GILLETT, LUCILE, A.

Inventor name: OLLMANN, MICHAEL, MARTIN

Inventor name: SONG, CHUNYAN

Inventor name: TAI, ALBERT, K.

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