EP1576010A4 - THERAPEUTIC COMPOSITIONS AND METHODS FOR CANCER CHARACTERIZED BY EXPRESSION OF MN / CA IX ANTIGEN ASSOCIATED WITH TUMORS - Google Patents

THERAPEUTIC COMPOSITIONS AND METHODS FOR CANCER CHARACTERIZED BY EXPRESSION OF MN / CA IX ANTIGEN ASSOCIATED WITH TUMORS

Info

Publication number
EP1576010A4
EP1576010A4 EP03749129A EP03749129A EP1576010A4 EP 1576010 A4 EP1576010 A4 EP 1576010A4 EP 03749129 A EP03749129 A EP 03749129A EP 03749129 A EP03749129 A EP 03749129A EP 1576010 A4 EP1576010 A4 EP 1576010A4
Authority
EP
European Patent Office
Prior art keywords
tumor
therapy
expression
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03749129A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1576010A2 (en
Inventor
Justin Wong
Jill Winter
Guita Lalehzadeh
Robert Warne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of EP1576010A2 publication Critical patent/EP1576010A2/en
Publication of EP1576010A4 publication Critical patent/EP1576010A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP03749129A 2002-08-23 2003-08-25 THERAPEUTIC COMPOSITIONS AND METHODS FOR CANCER CHARACTERIZED BY EXPRESSION OF MN / CA IX ANTIGEN ASSOCIATED WITH TUMORS Withdrawn EP1576010A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US40557702P 2002-08-23 2002-08-23
US405577P 2002-08-23
US64693403A 2003-08-22 2003-08-22
US646934 2003-08-22
PCT/US2003/026612 WO2004017923A2 (en) 2002-08-23 2003-08-25 Compositions and methods of therapy for cancers characterized by expression of the tumor-associated antigen mn/ca ix

Publications (2)

Publication Number Publication Date
EP1576010A2 EP1576010A2 (en) 2005-09-21
EP1576010A4 true EP1576010A4 (en) 2006-12-27

Family

ID=31949897

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03749129A Withdrawn EP1576010A4 (en) 2002-08-23 2003-08-25 THERAPEUTIC COMPOSITIONS AND METHODS FOR CANCER CHARACTERIZED BY EXPRESSION OF MN / CA IX ANTIGEN ASSOCIATED WITH TUMORS

Country Status (5)

Country Link
EP (1) EP1576010A4 (enExample)
JP (1) JP2005536220A (enExample)
AU (1) AU2003268180A1 (enExample)
CA (1) CA2496572A1 (enExample)
WO (1) WO2004017923A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2477163C (en) 2002-02-21 2010-07-27 Institute Of Virology Soluble form of carbonic anhydrase ix (s-ca-ix), assays to detect s-ca ix, and ca ix's coexpression with her-2/neu/c-erbb-2, and ca ix-specific monoclonal antibodies to non-immunodominant epitopes
US7833734B2 (en) 2002-11-26 2010-11-16 Institute Of Virology Of The Slovak Academy Of Sciences CA IX-specific inhibitors
DOP2006000277A (es) * 2005-12-12 2007-08-31 Bayer Pharmaceuticals Corp Anticuerpos anti mn y métodos para su utilización
WO2008091798A2 (en) * 2007-01-22 2008-07-31 Xencor, Inc. Optimized ca9 antibodies and methods of using the same
US20110015158A1 (en) * 2007-12-11 2011-01-20 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
EP3966253A4 (en) * 2019-05-06 2023-02-22 Navi Bio-Therapeutics, Inc. ANTI-CARBONIC ANHYDRASE IX ANTIBODIES

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024913A2 (en) * 1998-10-23 2000-05-04 Bayer Corporation Mn gene and protein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955075A (en) * 1992-03-11 1999-09-21 Institute Of Virology, Slovak Academy Of Sciences Method of inhibiting tumor growth using antibodies to MN protein

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024913A2 (en) * 1998-10-23 2000-05-04 Bayer Corporation Mn gene and protein

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. SAARNIO ET EL.: "Immunohistochemical study of colorectal tumors for expression of a novel transmembrane carbonic anhydrase, MN/CA IX, with potential value as a marker of cell proliferation.", AMERICAN JOURNAL OF PATHOLOGY, vol. 153, no. 1, 1998, pages 279 - 285 *

Also Published As

Publication number Publication date
WO2004017923A2 (en) 2004-03-04
JP2005536220A (ja) 2005-12-02
WO2004017923A3 (en) 2005-07-14
EP1576010A2 (en) 2005-09-21
CA2496572A1 (en) 2004-03-04
AU2003268180A8 (en) 2004-03-11
AU2003268180A1 (en) 2004-03-11

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20050315

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20061128

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC.

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Effective date: 20090602

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Effective date: 20091123