EP1558626A4 - Target detection system having a conformationally sensitive probe comprising a nucleic acid based signal transducer - Google Patents

Target detection system having a conformationally sensitive probe comprising a nucleic acid based signal transducer

Info

Publication number
EP1558626A4
EP1558626A4 EP03751517A EP03751517A EP1558626A4 EP 1558626 A4 EP1558626 A4 EP 1558626A4 EP 03751517 A EP03751517 A EP 03751517A EP 03751517 A EP03751517 A EP 03751517A EP 1558626 A4 EP1558626 A4 EP 1558626A4
Authority
EP
European Patent Office
Prior art keywords
nucleic acid
detection system
target detection
acid based
signal transducer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03751517A
Other languages
German (de)
French (fr)
Other versions
EP1558626A1 (en
Inventor
Keun Ho Chun
Hyun Jin Hwang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ahram Biosystems Inc
Original Assignee
Ahram Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ahram Biosystems Inc filed Critical Ahram Biosystems Inc
Publication of EP1558626A1 publication Critical patent/EP1558626A1/en
Publication of EP1558626A4 publication Critical patent/EP1558626A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
EP03751517A 2002-10-11 2003-10-11 Target detection system having a conformationally sensitive probe comprising a nucleic acid based signal transducer Withdrawn EP1558626A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41786402P 2002-10-11 2002-10-11
US417864P 2002-10-11
PCT/KR2003/002101 WO2004033476A1 (en) 2002-10-11 2003-10-11 Target detection system having a conformationally sensitive probe comprising a nucleic acid based signal transducer

Publications (2)

Publication Number Publication Date
EP1558626A1 EP1558626A1 (en) 2005-08-03
EP1558626A4 true EP1558626A4 (en) 2007-10-31

Family

ID=32094107

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03751517A Withdrawn EP1558626A4 (en) 2002-10-11 2003-10-11 Target detection system having a conformationally sensitive probe comprising a nucleic acid based signal transducer

Country Status (4)

Country Link
EP (1) EP1558626A4 (en)
JP (2) JP2006513701A (en)
AU (1) AU2003269522A1 (en)
WO (1) WO2004033476A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080200347A1 (en) * 2005-01-14 2008-08-21 Ngk Insulators, Ltd. Array and Hybridization Method
EP1853732A2 (en) * 2005-02-28 2007-11-14 Gen-Probe Incorporated Compositions and methods of detecting an analyte by using a nucleic acid hybridization switch probe
JP2011067174A (en) * 2009-09-28 2011-04-07 Fujitsu Ltd Target detector and method for producing the same
FR2998969B1 (en) * 2012-12-04 2015-01-09 Univ Limoges USE OF BIOTIN GRAFFEE FOR THE METAL DETERMINATION IN A SOLUTION
WO2016163345A1 (en) * 2015-04-07 2016-10-13 コニカミノルタ株式会社 Nucleic acid probe
SG11202007652UA (en) 2018-02-21 2020-09-29 Bristol Myers Squibb Co Camk2d antisense oligonucleotides and uses thereof

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283174A (en) * 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
WO1997009342A1 (en) * 1995-09-08 1997-03-13 Scriptgen Pharmaceuticals, Inc. Screen for compounds with affinity for rna
US5658732A (en) * 1989-10-04 1997-08-19 E. I. Du Pont De Nemours And Company Assay method for biological target complexes on the surface of a biosensor
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
WO2001085997A1 (en) * 2000-05-08 2001-11-15 Qtl Biosystems Llc Improvements to the fluorescent polymer-qtl approach to biosensing
US6361942B1 (en) * 1998-03-24 2002-03-26 Boston Probes, Inc. Method, kits and compositions pertaining to detection complexes
US6399302B1 (en) * 1998-08-21 2002-06-04 University Of Virginia Patent Foundation Signal generating oligonucleotide-based biosensor
US20020142300A1 (en) * 2000-01-25 2002-10-03 Bernard Philip S. Simultaneous screening and identification of sequence alterations from amplified target

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE88761T1 (en) * 1986-01-10 1993-05-15 Amoco Corp COMPETITIVE HOMOGENEOUS TEST.
US6255048B1 (en) * 1996-06-10 2001-07-03 Laboratory Of Molecular Biophotonics Highly sensitive fluoroassay
DE19950969A1 (en) * 1999-10-22 2001-05-10 Aventis Res & Tech Gmbh & Co Double-stranded nucleic acid probes and their use

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283174A (en) * 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5658732A (en) * 1989-10-04 1997-08-19 E. I. Du Pont De Nemours And Company Assay method for biological target complexes on the surface of a biosensor
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
WO1997009342A1 (en) * 1995-09-08 1997-03-13 Scriptgen Pharmaceuticals, Inc. Screen for compounds with affinity for rna
US6361942B1 (en) * 1998-03-24 2002-03-26 Boston Probes, Inc. Method, kits and compositions pertaining to detection complexes
US6399302B1 (en) * 1998-08-21 2002-06-04 University Of Virginia Patent Foundation Signal generating oligonucleotide-based biosensor
US20020142300A1 (en) * 2000-01-25 2002-10-03 Bernard Philip S. Simultaneous screening and identification of sequence alterations from amplified target
WO2001085997A1 (en) * 2000-05-08 2001-11-15 Qtl Biosystems Llc Improvements to the fluorescent polymer-qtl approach to biosensing

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
BRIGATI D J ET AL: "Detection of viral genomes in cultured cells and paraffin-embedded tissue sections using biotin-labeled hybridization probes.", VIROLOGY 15 APR 1983, vol. 126, no. 1, 15 April 1983 (1983-04-15), pages 32 - 50, XP002431733, ISSN: 0042-6822 *
COOK A F ET AL: "SYNTHESIS AND HYBRIDIZATION OF A SERIES OF BIOTINYLATED OLIGONUCLEOTIDES", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 16, no. 9, 11 May 1988 (1988-05-11), pages 4077 - 4095, XP000453559, ISSN: 0305-1048 *
FANG X ET AL: "Designing a novel molecular beacon for surface-immobilized DNA hybridization studies", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 121, no. 12, 31 March 1999 (1999-03-31), pages 2921 - 2922, XP002315845, ISSN: 0002-7863 *
MORRIS P D ET AL: "Biotin-streptavidin-labeled oligonucleotides as probes of helicase mechanisms.", METHODS (SAN DIEGO, CALIF.) FEB 2001, vol. 23, no. 2, February 2001 (2001-02-01), pages 149 - 159, XP002431731, ISSN: 1046-2023 *
RICCELLI P V ET AL: "Hybridization of single-stranded DNA targets to immobilized complementary DNA probes: comparison of hairpin versus linear capture probes", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 29, no. 4, 15 February 2001 (2001-02-15), pages 996 - 1004, XP002282478, ISSN: 0305-1048 *
See also references of WO2004033476A1 *
SOH J ET AL: "Hybrid selection of mRNA with biotinylated DNA.", GENETIC ANALYSIS, TECHNIQUES AND APPLICATIONS JUN 1990, vol. 7, no. 4, June 1990 (1990-06-01), pages 80 - 86, XP002431732, ISSN: 1050-3862 *
TELSER J ET AL: "Synthesis and characterization of DNA oligomers and duplexes containing covalently attached molecular labels: Comparison of biotin, fluorescein, and pyrene labels by thermodynamic and optical spectroscopic measurements", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 1989 UNITED STATES, vol. 111, no. 18, 1989, pages 6966 - 6976, XP002431734, ISSN: 0002-7863 *
TYAGI S ET AL: "MOLECULAR BEACONS: PROBES THAT FLUORESCE UPON HYBRIDIZATION", BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, vol. 14, March 1996 (1996-03-01), pages 303 - 308, XP002926498, ISSN: 0733-222X *

Also Published As

Publication number Publication date
EP1558626A1 (en) 2005-08-03
JP2010099090A (en) 2010-05-06
JP2006513701A (en) 2006-04-27
AU2003269522A1 (en) 2004-05-04
WO2004033476A1 (en) 2004-04-22

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