EP1552012A4 - Gene de predisposition pour l'attaque chez l'homme, et procedes de traitement - Google Patents

Gene de predisposition pour l'attaque chez l'homme, et procedes de traitement

Info

Publication number
EP1552012A4
EP1552012A4 EP03770392A EP03770392A EP1552012A4 EP 1552012 A4 EP1552012 A4 EP 1552012A4 EP 03770392 A EP03770392 A EP 03770392A EP 03770392 A EP03770392 A EP 03770392A EP 1552012 A4 EP1552012 A4 EP 1552012A4
Authority
EP
European Patent Office
Prior art keywords
treatment
methods
susceptibility gene
human stroke
stroke
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03770392A
Other languages
German (de)
English (en)
Other versions
EP1552012A2 (fr
Inventor
Solveig Gretarsdottir
Sigridur Th Reynisdottir
Gudmar Thorleifsson
Jeffrey R Gulcher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Decode Genetics ehf
Original Assignee
Decode Genetics ehf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/255,120 external-priority patent/US20040091865A1/en
Priority claimed from US10/419,723 external-priority patent/US20040014099A1/en
Application filed by Decode Genetics ehf filed Critical Decode Genetics ehf
Priority claimed from PCT/US2003/029906 external-priority patent/WO2004028341A2/fr
Publication of EP1552012A2 publication Critical patent/EP1552012A2/fr
Publication of EP1552012A4 publication Critical patent/EP1552012A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP03770392A 2002-09-25 2003-09-25 Gene de predisposition pour l'attaque chez l'homme, et procedes de traitement Withdrawn EP1552012A4 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US650120 1996-06-03
US255120 2002-09-25
US10/255,120 US20040091865A1 (en) 2001-03-19 2002-09-25 Human stroke gene
US419723 2003-04-18
US10/419,723 US20040014099A1 (en) 2001-03-19 2003-04-18 Susceptibility gene for human stroke; methods of treatment
US65012003A 2003-08-27 2003-08-27
PCT/US2003/029906 WO2004028341A2 (fr) 2001-03-19 2003-09-25 Gene de predisposition pour l'attaque chez l'homme, et procedes de traitement

Publications (2)

Publication Number Publication Date
EP1552012A2 EP1552012A2 (fr) 2005-07-13
EP1552012A4 true EP1552012A4 (fr) 2006-06-07

Family

ID=56290488

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03770392A Withdrawn EP1552012A4 (fr) 2002-09-25 2003-09-25 Gene de predisposition pour l'attaque chez l'homme, et procedes de traitement

Country Status (4)

Country Link
EP (1) EP1552012A4 (fr)
JP (1) JP2006500068A (fr)
AU (1) AU2003278877A1 (fr)
CA (1) CA2499320A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109298133B (zh) * 2018-07-18 2021-07-13 重庆邮电大学 基于边缘通道校正的探测器模块生产良品率改进方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023091A2 (fr) * 1998-10-15 2000-04-27 Bioimage A/S Interventions therapeutiques specifiques obtenues par interference avec redistribution et ou ciblage
WO2000040714A2 (fr) * 1998-12-30 2000-07-13 Oligos Etc. Inc. Inhibiteurs de la phosphodiesterase utilises a des fins therapeutiques
WO2001000851A1 (fr) * 1999-06-25 2001-01-04 Memory Pharmaceutical Corporation Isoformes de phosphodiesterase de l'amp cyclique et procedes d'utilisation
WO2002074992A2 (fr) * 2001-03-19 2002-09-26 Decode Genetics Ehf. Gene humain implique dans l'accident vasculaire cerebral

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023091A2 (fr) * 1998-10-15 2000-04-27 Bioimage A/S Interventions therapeutiques specifiques obtenues par interference avec redistribution et ou ciblage
WO2000040714A2 (fr) * 1998-12-30 2000-07-13 Oligos Etc. Inc. Inhibiteurs de la phosphodiesterase utilises a des fins therapeutiques
WO2001000851A1 (fr) * 1999-06-25 2001-01-04 Memory Pharmaceutical Corporation Isoformes de phosphodiesterase de l'amp cyclique et procedes d'utilisation
WO2002074992A2 (fr) * 2001-03-19 2002-09-26 Decode Genetics Ehf. Gene humain implique dans l'accident vasculaire cerebral

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GRAEME B BOLGER ET AL: "Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene", BIOCHEMICAL JOURNAL, PORTLAND PRESS, LONDON, GB, vol. 328, 1997, pages 539 - 548, XP002150449, ISSN: 0264-6021 *
GRETARSDOTTIR SOLVEIG ET AL: "Localization of a susceptibility gene for common forms of stroke to 5q12", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 70, no. 3, March 2002 (2002-03-01), pages 593 - 603, XP002376109, ISSN: 0002-9297 *
GRETARSDOTTIR SOLVEIG ET AL: "The gene encoding phosphodiesterase 4D confers risk of ischemic stroke.", NATURE GENETICS, vol. 35, no. 2, October 2003 (2003-10-01), pages 131 - 138, XP002376110, ISSN: 1061-4036 *
KOSTIC M M ET AL: "Altered expression of PDE1 and PDE4 cyclic nucleotide phosphodiesterase isoforms in 7-oxo-prostacyclin-preconditioned rat heart", JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, vol. 29, no. 11, November 1997 (1997-11-01), pages 3135 - 3146, XP002278927, ISSN: 0022-2828 *
PEREZ-TORRES S ET AL: "Phosphodiesterase type 4 isozymes expression in human brain examined by in situ hybridization histochemistry and (3H)rolipram binding autoradiography comparison with monkey and rat brain", JOURNAL OF CHEMICAL NEUROANATOMY, CHICHESTER, GB, vol. 20, no. 3-4, December 2000 (2000-12-01), pages 349 - 374, XP002275597, ISSN: 0891-0618 *

Also Published As

Publication number Publication date
EP1552012A2 (fr) 2005-07-13
CA2499320A1 (fr) 2004-04-08
JP2006500068A (ja) 2006-01-05
AU2003278877A8 (en) 2004-04-19
AU2003278877A1 (en) 2004-04-19

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20050418

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20060425

17Q First examination report despatched

Effective date: 20060904

RIN1 Information on inventor provided before grant (corrected)

Inventor name: GULCHER, JEFFREY, R.

Inventor name: THORLEIFSSON, GUDMAR

Inventor name: REYNISDOTTIR, SIGRIDUR, TH.

Inventor name: GRETARSDOTTIR, SOLVEIG

RIN1 Information on inventor provided before grant (corrected)

Inventor name: GULCHER, JEFFREY, R.

Inventor name: THORLEIFSSON, GUDMAR

Inventor name: REYNISDOTTIR, SIGRIDUR, TH.

Inventor name: GRETARSDOTTIR, SOLVEIG

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080925