EP1549616A4 - Sel d'acide organique d'amlodipine - Google Patents
Sel d'acide organique d'amlodipineInfo
- Publication number
- EP1549616A4 EP1549616A4 EP03771480A EP03771480A EP1549616A4 EP 1549616 A4 EP1549616 A4 EP 1549616A4 EP 03771480 A EP03771480 A EP 03771480A EP 03771480 A EP03771480 A EP 03771480A EP 1549616 A4 EP1549616 A4 EP 1549616A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- amlodipine
- organic acid
- acid salt
- salt
- organic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020020044856A KR20040011751A (ko) | 2002-07-30 | 2002-07-30 | 암로디핀의 유기산염 |
KR2002044856 | 2002-07-30 | ||
PCT/KR2003/001522 WO2004011432A1 (fr) | 2002-07-30 | 2003-07-30 | Sel d'acide organique d'amlodipine |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1549616A1 EP1549616A1 (fr) | 2005-07-06 |
EP1549616A4 true EP1549616A4 (fr) | 2006-10-18 |
Family
ID=31185754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03771480A Withdrawn EP1549616A4 (fr) | 2002-07-30 | 2003-07-30 | Sel d'acide organique d'amlodipine |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1549616A4 (fr) |
JP (1) | JP2005538103A (fr) |
KR (1) | KR20040011751A (fr) |
CN (1) | CN1678583A (fr) |
AU (1) | AU2003247208A1 (fr) |
BR (1) | BR0313076A (fr) |
MX (1) | MXPA05001241A (fr) |
WO (1) | WO2004011432A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100913791B1 (ko) * | 2006-07-21 | 2009-08-26 | 한미약품 주식회사 | (s)-(-)-암로디핀 캠실레이트 또는 이의 수화물 및 이를함유하는 약학적 조성물 |
KR100821688B1 (ko) | 2006-08-10 | 2008-04-11 | (주)유케이케미팜 | 암로디핀 라셈화물의 입체이성질체의 분리방법과 그의친수성 약물 및 그의 제조방법 |
KR20120127495A (ko) | 2010-02-12 | 2012-11-21 | 화이자 인코포레이티드 | 8-플루오로-2-{4-[(메틸아미노)메틸]페닐}-1,3,4,5-테트라하이드로-6h-아제피노[5,4,3-cd]인돌-6-온의 염 및 다형체 |
CN101972254B (zh) * | 2010-09-28 | 2012-05-30 | 石药集团欧意药业有限公司 | 一种左旋氨氯地平或其可药用盐固体制剂及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
GB8608335D0 (en) * | 1986-04-04 | 1986-05-08 | Pfizer Ltd | Pharmaceutically acceptable salts |
GB8710493D0 (en) * | 1987-05-02 | 1987-06-03 | Pfizer Ltd | Dihydropyridines |
US6057344A (en) * | 1991-11-26 | 2000-05-02 | Sepracor, Inc. | Methods for treating hypertension, and angina using optically pure (-) amlodipine |
KR100452491B1 (ko) * | 2001-03-29 | 2004-10-12 | 한미약품 주식회사 | 신규한 결정형 암로디핀 캠실레이트 염 및 그의 제조방법 |
-
2002
- 2002-07-30 KR KR1020020044856A patent/KR20040011751A/ko not_active Application Discontinuation
-
2003
- 2003-07-30 EP EP03771480A patent/EP1549616A4/fr not_active Withdrawn
- 2003-07-30 AU AU2003247208A patent/AU2003247208A1/en not_active Abandoned
- 2003-07-30 CN CNA038208768A patent/CN1678583A/zh active Pending
- 2003-07-30 BR BR0313076-2A patent/BR0313076A/pt not_active IP Right Cessation
- 2003-07-30 WO PCT/KR2003/001522 patent/WO2004011432A1/fr active Application Filing
- 2003-07-30 JP JP2004524369A patent/JP2005538103A/ja active Pending
- 2003-07-30 MX MXPA05001241A patent/MXPA05001241A/es unknown
Non-Patent Citations (1)
Title |
---|
JOSEFSSON M ET AL: "Chiral ion-pair chromatographic separation of two dihydropyridines with camphorsulfonic acids on porous graphitic carbon", 28 October 1994, JOURNAL OF CHROMATOGRAPHY A, ELSEVIER, AMSTERDAM, NL, PAGE(S) 23-27, ISSN: 0021-9673, XP004174362 * |
Also Published As
Publication number | Publication date |
---|---|
CN1678583A (zh) | 2005-10-05 |
MXPA05001241A (es) | 2005-06-08 |
BR0313076A (pt) | 2005-06-28 |
AU2003247208A1 (en) | 2004-02-16 |
WO2004011432A1 (fr) | 2004-02-05 |
KR20040011751A (ko) | 2004-02-11 |
EP1549616A1 (fr) | 2005-07-06 |
JP2005538103A (ja) | 2005-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20050301 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20060915 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 9/12 20060101ALI20060911BHEP Ipc: A61K 31/4422 20060101ALI20060911BHEP Ipc: C07D 211/86 20060101ALI20060911BHEP Ipc: C07D 211/90 20060101AFI20060911BHEP |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: KANG, HYUN-SUK,102-1307, SEOCHO HYUNDAI APT Inventor name: PARK, KYUNG-MI,110-506, HANGANG HYUNDAI APT Inventor name: KIM, YUN-CHEUL,202368-2 BULKWANG 3-DONG Inventor name: YEON, KYU-JEONG,126-801, YEONWONMAUL SAMHOBY APT Inventor name: LIM, DONG-KWON,201-1804, CCACHIMAUL Inventor name: JUNG, SUNG-HAK,47-402, JOOGONG APT Inventor name: LEE, SUNG-HAK,103-1004, HYUNDAI APT Inventor name: JIN, HAE-TAK,105-1406, HYUNDAI APT Inventor name: CHEON, JUN-HEE,149-904, HWANGGOLMAUL Inventor name: KIM, YOUNG-HOON,108-309, HYUNDAI APT Inventor name: JEONG, EUN-JU,101-1102, MOCKHWA APT Inventor name: LEE, KWANG-HYEG,702-402, MOCKRYUNMAUL HWASEONG-V Inventor name: LEE, HYUK-KOO,101-902, LIFE APT Inventor name: PARK, CHOONG-SIL,D-203, HEIGHTS VILLA Inventor name: JUNG, YUN-TAEK,102-902, HALLA APT Inventor name: YOUN, YONG-SIK,105-104 BYCOKSAN APARTMENT Inventor name: CHO, SEONG-HWAN,721-602, HYUNDAI APT |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: KANG, HYUN-SUK,102-1307, SEOCHO HYUNDAI APT Inventor name: PARK, KYUNG-MI,110-506, HANGANG HYUNDAI APT Inventor name: KIM, YUN-CHEUL,202368-2 BULKWANG 3-DONG Inventor name: YEON, KYU-JEONG,126-801, YEONWONMAUL SAMHOBY APT Inventor name: LIM, DONG-KWON,201-1804, CCACHIMAUL Inventor name: JUNG, SUNG-HAK,47-402, JOOGONG APT Inventor name: LEE, SUNG-HAK,103-1004, HYUNDAI APT Inventor name: JIN, HAE-TAK,105-1406, HYUNDAI APT Inventor name: CHEON, JUN-HEE,149-904, HWANGGOLMAUL Inventor name: KIM, YOUNG-HOON,108-309, HYUNDAI APT Inventor name: JEONG, EUN-JU,101-1102, MOCKHWA APT Inventor name: LEE, KWANG-HYEG,702-402, MOCKRYUNMAUL HWASEONG-V Inventor name: LEE, HYUK-KOO,101-902, LIFE APT Inventor name: PARK, CHOONG-SIL,D-203, HEIGHTS VILLA Inventor name: JUNG, YUN-TAEK,102-902, HALLA APT Inventor name: YOUN, YONG-SIK,105-104 BYCOKSAN APARTMENT Inventor name: CHO, SEONG-HWAN,721-602, HYUNDAI APT |
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17Q | First examination report despatched |
Effective date: 20071114 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20080326 |