EP1546400A4 - Tamis a haut rendement pour modulateurs de l'activite de modification de la chromatine - Google Patents

Tamis a haut rendement pour modulateurs de l'activite de modification de la chromatine

Info

Publication number
EP1546400A4
EP1546400A4 EP03793288A EP03793288A EP1546400A4 EP 1546400 A4 EP1546400 A4 EP 1546400A4 EP 03793288 A EP03793288 A EP 03793288A EP 03793288 A EP03793288 A EP 03793288A EP 1546400 A4 EP1546400 A4 EP 1546400A4
Authority
EP
European Patent Office
Prior art keywords
modulators
throughput screen
modifying activity
chromatin modifying
chromatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03793288A
Other languages
German (de)
English (en)
Other versions
EP1546400A2 (fr
Inventor
Andrew Snowden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sangamo Therapeutics Inc
Original Assignee
Sangamo Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sangamo Biosciences Inc filed Critical Sangamo Biosciences Inc
Publication of EP1546400A2 publication Critical patent/EP1546400A2/fr
Publication of EP1546400A4 publication Critical patent/EP1546400A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP03793288A 2002-08-23 2003-08-22 Tamis a haut rendement pour modulateurs de l'activite de modification de la chromatine Withdrawn EP1546400A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40542102P 2002-08-23 2002-08-23
US405421P 2002-08-23
PCT/US2003/026334 WO2004018632A2 (fr) 2002-08-23 2003-08-22 Tamis a haut rendement pour modulateurs de l'activite de modification de la chromatine

Publications (2)

Publication Number Publication Date
EP1546400A2 EP1546400A2 (fr) 2005-06-29
EP1546400A4 true EP1546400A4 (fr) 2007-09-19

Family

ID=31946870

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03793288A Withdrawn EP1546400A4 (fr) 2002-08-23 2003-08-22 Tamis a haut rendement pour modulateurs de l'activite de modification de la chromatine

Country Status (3)

Country Link
EP (1) EP1546400A4 (fr)
AU (1) AU2003262788A1 (fr)
WO (1) WO2004018632A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060275852A1 (en) 2005-06-06 2006-12-07 Montagu Jean I Assays based on liquid flow over arrays
EP3789492A1 (fr) * 2019-09-05 2021-03-10 Universität Stuttgart Analyse cellulaire basée sur la fluorescence pour la détection de l'activité régulatrice de gènes de protéines associées à la chromatine et complexes de protéines

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999023885A1 (fr) * 1997-11-10 1999-05-20 The Salk Institute For Biological Studies Methodes d'utilisation d'inhibiteurs de co-represseurs dans le cadre du traitement de maladies neoplasiques
EP1094112A2 (fr) * 1999-08-27 2001-04-25 Her Majesty in Right of Canada, as represented by The Minister of Agriculture and Agri-Food Repression de l'expression de gènes de plantes
WO2002092002A2 (fr) * 2001-05-11 2002-11-21 The Burnham Institute Methodes de criblage, methodes diagnostiques et therapeutiques relatives a riz

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4309051B2 (ja) * 1998-03-02 2009-08-05 マサチューセッツ インスティテュート オブ テクノロジー 改善したリンカーを有するポリジンクフィンガータンパク質
US6599692B1 (en) * 1999-09-14 2003-07-29 Sangamo Bioscience, Inc. Functional genomics using zinc finger proteins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999023885A1 (fr) * 1997-11-10 1999-05-20 The Salk Institute For Biological Studies Methodes d'utilisation d'inhibiteurs de co-represseurs dans le cadre du traitement de maladies neoplasiques
EP1094112A2 (fr) * 1999-08-27 2001-04-25 Her Majesty in Right of Canada, as represented by The Minister of Agriculture and Agri-Food Repression de l'expression de gènes de plantes
WO2002092002A2 (fr) * 2001-05-11 2002-11-21 The Burnham Institute Methodes de criblage, methodes diagnostiques et therapeutiques relatives a riz

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KALKHOVEN ERIC ET AL: "The PHD type zinc finger is an integral part of the CBP acetyltransferase domain", MOLECULAR AND CELLULAR BIOLOGY, vol. 22, no. 7, April 2002 (2002-04-01), pages 1961 - 1970, XP002446153, ISSN: 0270-7306 *
SNOWDEN ANDREW W ET AL: "Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors.", CANCER RESEARCH, vol. 63, no. 24, 15 December 2003 (2003-12-15), pages 8968 - 8976, XP002446154, ISSN: 0008-5472 *

Also Published As

Publication number Publication date
WO2004018632A2 (fr) 2004-03-04
AU2003262788A8 (en) 2004-03-11
EP1546400A2 (fr) 2005-06-29
AU2003262788A1 (en) 2004-03-11
WO2004018632A3 (fr) 2004-06-24

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Legal Events

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