EP1534837A4 - Apicomplexan pathways, inhibitiors, and drug delivery - Google Patents

Apicomplexan pathways, inhibitiors, and drug delivery

Info

Publication number
EP1534837A4
EP1534837A4 EP03788516A EP03788516A EP1534837A4 EP 1534837 A4 EP1534837 A4 EP 1534837A4 EP 03788516 A EP03788516 A EP 03788516A EP 03788516 A EP03788516 A EP 03788516A EP 1534837 A4 EP1534837 A4 EP 1534837A4
Authority
EP
European Patent Office
Prior art keywords
inhibitiors
apicomplexan
pathways
drug delivery
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03788516A
Other languages
German (de)
French (fr)
Other versions
EP1534837A2 (en
Inventor
Rima L Mcleod
Ernest Mui
Benjamin Samuel
Douglas G Mack
Michael Kirisits
Paul Wender
Jonathan Rothbard
Brian Hearn
Craig W Roberts
David W Rice
Stephen P Muench
Sean Prigge
Samantha A Campbell
John R Coggins
Fiona Roberts
Fiona L Henriquez
Wilbur K Milhous
Dennis E Kyle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1534837A2 publication Critical patent/EP1534837A2/en
Publication of EP1534837A4 publication Critical patent/EP1534837A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP03788516A 2002-08-15 2003-08-14 Apicomplexan pathways, inhibitiors, and drug delivery Withdrawn EP1534837A4 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US40403302P 2002-08-15 2002-08-15
US404033P 2002-08-15
US43820503P 2003-01-06 2003-01-06
US438205P 2003-01-06
US46343203P 2003-04-16 2003-04-16
US463432P 2003-04-16
US47288703P 2003-05-23 2003-05-23
US472887P 2003-05-23
PCT/US2003/025571 WO2004016220A2 (en) 2002-08-15 2003-08-14 Apicomplexan pathways, inhibitiors, and drug delivery

Publications (2)

Publication Number Publication Date
EP1534837A2 EP1534837A2 (en) 2005-06-01
EP1534837A4 true EP1534837A4 (en) 2006-09-20

Family

ID=31892261

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03788516A Withdrawn EP1534837A4 (en) 2002-08-15 2003-08-14 Apicomplexan pathways, inhibitiors, and drug delivery

Country Status (4)

Country Link
EP (1) EP1534837A4 (en)
AU (1) AU2003259848A1 (en)
CA (1) CA2535760A1 (en)
WO (1) WO2004016220A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6969514B2 (en) 2003-02-05 2005-11-29 Soll David B Method for treating elevated intraocular pressure, including glaucoma
WO2006095837A1 (en) * 2005-03-09 2006-09-14 National University Corporation Hokkaido University Lipid membrane structure capable of delivering target substance into mitochondrion

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998052614A2 (en) * 1997-05-21 1998-11-26 The Board Of Trustees Of The Leland Stanford Junior University Composition and method for enhancing transport across biological membranes
WO2001027262A1 (en) * 1999-10-13 2001-04-19 Pantheco A/S Gene selection using pnas
WO2002049576A2 (en) * 2000-12-21 2002-06-27 Rima Mcleod Fab i and inhibition of apicomplexan parasites

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403337B1 (en) * 1996-01-05 2002-06-11 Human Genome Sciences, Inc. Staphylococcus aureus genes and polypeptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998052614A2 (en) * 1997-05-21 1998-11-26 The Board Of Trustees Of The Leland Stanford Junior University Composition and method for enhancing transport across biological membranes
WO2001027262A1 (en) * 1999-10-13 2001-04-19 Pantheco A/S Gene selection using pnas
WO2002049576A2 (en) * 2000-12-21 2002-06-27 Rima Mcleod Fab i and inhibition of apicomplexan parasites

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MCLEOD R ET AL: "TRICLOSAN INHIBITS THE GROWTH OF PLASMODIUM FALCIPARUM AND TOXOPLASMA GONDII BY INHIBITION OF APICOMPLEXAN FAB I", INTERNATIONAL JOURNAL OF PARASITOLOGY, PERGAMON PRESS, GB, vol. 31, no. 2, 2001, pages 109 - 113, XP001205626, ISSN: 0020-7519 *
SAMUEL B U ET AL: "DELIVERY OF ANTIMICROBIALS INTO PARASITES", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 100, no. 24, SUPPL 2, 25 November 2003 (2003-11-25), pages 14281 - 14286, XP009045693, ISSN: 0027-8424 *
ZUTHER E ET AL: "GROWTH OF TOXOPLASMA GONDII IS INHIBITED BY ARYLOXYPHENOXYPROPIONATE HERBICIDES TARGETING ACETYL-COA CARBOXYLASE", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 96, no. 23, 9 November 1999 (1999-11-09), pages 13387 - 13392, XP000952826, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
EP1534837A2 (en) 2005-06-01
CA2535760A1 (en) 2004-02-26
AU2003259848A1 (en) 2004-03-03
WO2004016220A2 (en) 2004-02-26
WO2004016220A3 (en) 2005-02-24

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK

17P Request for examination filed

Effective date: 20050824

RBV Designated contracting states (corrected)

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
RIN1 Information on inventor provided before grant (corrected)

Inventor name: KYLE, DENNIS E.

Inventor name: MILHOUS, WILBUR K.

Inventor name: HENRIQUEZ, FIONA L.

Inventor name: ROBERTS, FIONA

Inventor name: COGGINS, JOHN R.

Inventor name: CAMPBELL, SAMANTHA A.

Inventor name: PRIGGE, SEAN

Inventor name: MUENCH, STEPHEN P.

Inventor name: RICE, DAVID W.

Inventor name: ROBERTS, CRAIG W.

Inventor name: HEARN, BRIAN

Inventor name: ROTHBARD, JONATHAN

Inventor name: WENDER, PAUL

Inventor name: KIRISITS, MICHAEL

Inventor name: MACK, DOUGLAS G.

Inventor name: SAMUEL, BENJAMIN

Inventor name: MUI, ERNEST

Inventor name: MCLEOD, RIMA L.

A4 Supplementary search report drawn up and despatched

Effective date: 20060821

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 47/48 20060101ALI20060814BHEP

Ipc: A61K 39/012 20060101ALI20060814BHEP

Ipc: C07H 21/04 20060101ALI20060814BHEP

Ipc: C12P 21/06 20060101ALI20060814BHEP

Ipc: C12N 15/63 20060101ALI20060814BHEP

Ipc: C12N 15/12 20060101ALI20060814BHEP

Ipc: C12N 5/10 20060101ALI20060814BHEP

Ipc: C12N 1/21 20060101ALI20060814BHEP

Ipc: C12N 15/31 20060101AFI20050314BHEP

17Q First examination report despatched

Effective date: 20080717

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18D Application deemed to be withdrawn

Effective date: 20110301