EP1513559A4 - Erhöhte abgabe eines nukleinsäure-konstrukts in vivo mit dem poly-l-glutamat (plg) system - Google Patents

Erhöhte abgabe eines nukleinsäure-konstrukts in vivo mit dem poly-l-glutamat (plg) system

Info

Publication number
EP1513559A4
EP1513559A4 EP03741818A EP03741818A EP1513559A4 EP 1513559 A4 EP1513559 A4 EP 1513559A4 EP 03741818 A EP03741818 A EP 03741818A EP 03741818 A EP03741818 A EP 03741818A EP 1513559 A4 EP1513559 A4 EP 1513559A4
Authority
EP
European Patent Office
Prior art keywords
constrtuct
plg
glutamate
vivo
poly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03741818A
Other languages
English (en)
French (fr)
Other versions
EP1513559A1 (de
Inventor
Ruxandra Draghia-Akli
Robert H Carpenter
Douglas R Kern
Leigh Anne Hill
Heather Attra
Henry Hebel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advisys Inc
Original Assignee
Advisys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/395,709 external-priority patent/US20040014645A1/en
Application filed by Advisys Inc filed Critical Advisys Inc
Publication of EP1513559A1 publication Critical patent/EP1513559A1/de
Publication of EP1513559A4 publication Critical patent/EP1513559A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP03741818A 2002-05-28 2003-05-23 Erhöhte abgabe eines nukleinsäure-konstrukts in vivo mit dem poly-l-glutamat (plg) system Withdrawn EP1513559A4 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15667002A 2002-05-28 2002-05-28
US156670 2002-05-28
US10/395,709 US20040014645A1 (en) 2002-05-28 2003-03-24 Increased delivery of a nucleic acid construct in vivo by the poly-L-glutamate ("PLG") system
US395709 2003-03-24
PCT/US2003/016541 WO2003099341A1 (en) 2002-05-28 2003-05-23 Increased delivery of a nucleic acid constrtuct in vivo by the poly-l-glutamate (plg) system

Publications (2)

Publication Number Publication Date
EP1513559A1 EP1513559A1 (de) 2005-03-16
EP1513559A4 true EP1513559A4 (de) 2006-01-18

Family

ID=29586320

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03741818A Withdrawn EP1513559A4 (de) 2002-05-28 2003-05-23 Erhöhte abgabe eines nukleinsäure-konstrukts in vivo mit dem poly-l-glutamat (plg) system

Country Status (7)

Country Link
EP (1) EP1513559A4 (de)
CN (1) CN1662261A (de)
AU (1) AU2003273142A1 (de)
BR (1) BR0311539A (de)
CA (1) CA2485976A1 (de)
MX (1) MXPA04011766A (de)
WO (1) WO2003099341A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2005089810A1 (ja) * 2004-03-22 2008-01-31 関西ティー・エル・オー株式会社 エレクトロポレーション法を用いたヒト骨形成因子遺伝子導入による骨誘導方法
NZ553274A (en) * 2004-07-23 2010-02-26 VGX Pharmaceuticals LLC Growth hormone releasing hormone enhances the immune response induced by vaccination

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001006988A2 (en) * 1999-07-26 2001-02-01 Baylor College Of Medicine Super-active porcine growth hormone releasing hormone analog
WO2001066149A2 (en) * 2000-03-03 2001-09-13 Valentis, Inc. Nucleic acid formulations for gene delivery and methods of use
WO2003049700A2 (en) * 2001-12-11 2003-06-19 Advisys, Inc. Growth hormone releasing hormone suplementation for treating chronically ill subjects

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001006988A2 (en) * 1999-07-26 2001-02-01 Baylor College Of Medicine Super-active porcine growth hormone releasing hormone analog
WO2001066149A2 (en) * 2000-03-03 2001-09-13 Valentis, Inc. Nucleic acid formulations for gene delivery and methods of use
WO2003049700A2 (en) * 2001-12-11 2003-06-19 Advisys, Inc. Growth hormone releasing hormone suplementation for treating chronically ill subjects

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DRAGHIA-AKLI R ET AL: "ELECTRICAL ENHANCEMENT OF FORMULATED PLASMID DELIVERY IN ANIMALS", TECHNOLOGY IN CANCER RESEARCH AND TREATMENT, ADENINE PRESS, SCHENECTADY, NY, US, vol. 1, no. 5, October 2002 (2002-10-01), pages 365 - 371, XP001182428, ISSN: 1533-0346 *
FEWELL J G ET AL: "Gene therapy for the treatment of hemophilia B using PINC-formulated plasmid delivered to muscle with electroporation", MOLECULAR THERAPY, ACADEMIC PRESS, SAN DIEGO, CA,, US, vol. 3, no. 4, April 2001 (2001-04-01), pages 574 - 583, XP002965532, ISSN: 1525-0016 *
See also references of WO03099341A1 *

Also Published As

Publication number Publication date
CA2485976A1 (en) 2003-12-04
BR0311539A (pt) 2005-10-25
AU2003273142A1 (en) 2003-12-12
MXPA04011766A (es) 2005-03-31
CN1662261A (zh) 2005-08-31
EP1513559A1 (de) 2005-03-16
WO2003099341A1 (en) 2003-12-04

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Legal Events

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Ipc: 7C 07K 14/60 B

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DAX Request for extension of the european patent (deleted)
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