EP1501459A4 - Blutgerinnselfilter - Google Patents

Blutgerinnselfilter

Info

Publication number
EP1501459A4
EP1501459A4 EP03718415A EP03718415A EP1501459A4 EP 1501459 A4 EP1501459 A4 EP 1501459A4 EP 03718415 A EP03718415 A EP 03718415A EP 03718415 A EP03718415 A EP 03718415A EP 1501459 A4 EP1501459 A4 EP 1501459A4
Authority
EP
European Patent Office
Prior art keywords
filter
struts
vascular lumen
wall
connecting element
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03718415A
Other languages
English (en)
French (fr)
Other versions
EP1501459A2 (de
Inventor
Ted Beyer
William M Appling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angiodynamics Inc
Original Assignee
Angiodynamics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiodynamics Inc filed Critical Angiodynamics Inc
Publication of EP1501459A2 publication Critical patent/EP1501459A2/de
Publication of EP1501459A4 publication Critical patent/EP1501459A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2/0103—With centering means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2/0105—Open ended, i.e. legs gathered only at one side
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01—Filters implantable into blood vessels
    • A61F2002/016—Filters implantable into blood vessels made from wire-like elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0028—Shapes in the form of latin or greek characters
    • A61F2230/005—Rosette-shaped, e.g. star-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0073—Quadric-shaped
    • A61F2230/008—Quadric-shaped paraboloidal

Definitions

  • This invention relates in general to a blood clot filter and more particularly to one that can be inactivated without being removed from the vascular lumen .
  • Blood clot filters of the type disclosed herein are normally deployed in the inferior vena cava . It is known in the art to have permanent blood clot filters, temporary blood clot filters and blood clot filters which can be converted from being a filter to a non-filtered state without requiring removal thereof.
  • a large number of different blood clot filter designs are known for various techniques that provide various degrees of centering, filter efficiency, blood flow characteristics and ease or difficulty of removal. Certain filters are designed so that the filter can be left in the patient when the filtering function is no longer required.
  • the embodiment disclosed employs a multi-strut zig-zag cylindrical positioning portion that is adapted to sit against the wall of a vascular lumen.
  • This positioning portion is composed of twelve struts in one embodiment .
  • the active portion of the filter involves a number of resilient struts.
  • Each of these filter struts has a first end connected to one of the twelve struts of the positioning portion.
  • the first end of each filter strut is at the vascular lumen wall .
  • a second end of each filter strut is held in a central position within the lumen by a frangible connecting element such as a piece of surgical string.
  • the connecting element has a small central opening so that the faster flowing blood at the center of the vascular lumen can pass through carrying small clots that do not create potential damage. This central opening also assures the blood flow will dissolve the clots caught by the filter.
  • FIG. 1 is a schematic side view of an embodiment of the filter of this invention positioned in the wall of the vascular system.
  • FIG. 1 illustrates the filter state of the filter with some of the structure removed for clarity.
  • FIG. 2 is an end view of the FIG. 1 device in the deployed filter state.
  • FIG. 3 shows an intermediate fabrication condition in which positioning struts 14 and filter struts 16 have been cut out of a sheet of stainless steel prior to being formed into a cylindrical shape.
  • FIG. 3A is a larger scale view of the downstream end of each filter strut 16, showing a small opening 24 to accommodate the connecting element that holds that end of each filter strut near the center of the vascular lumen within which the filter is positioned.
  • FIG. 3B is a larger scale view of one end or corner of the zig-zag set of positioning struts 14 that constitute the positioning portion of the filter; which positioning portion lies against the vascular wall.
  • FIG. 3C is a larger scale illustration of the corner or end where two of the filter struts 16 join with two of the positioning struts 14 at the vascular wall.
  • FIG. 3C also illustrates the barb 20 which is used to fasten the filter to the vascular wall .
  • FIG. 3D is a larger scale view of one of the filter struts 16.
  • FIG. 4 is a schematic longitudinal sectional view of the FIG. 1 filter in the inactive state, after the connector 18 has been cut.
  • the FIGs. all relate to the same embodiment.
  • the self-centering blood clot filter 10 is shown in FIGs. 1 and 2 in its filter state.
  • the filter 10 is deployed in a vascular lumen defined by a vascular wall 12.
  • the filter is composed of a plurality of struts 14,16.
  • Half of the struts are the struts 14 which are deployed in a zig-zag fashion against the inner surface of the vascular wall 12 to provide a positioning function.
  • the other half are the struts 16 are deployed within the lumen to provide a blood clot filtering function.
  • the filter 10 has a multi-strut 14 positioning portion and a multi-strut 16 filtering portion.
  • the set of positioning struts 14 have a zig-zag cylindrical deployment against the inner surface of the vascular wall 12.
  • Each filter strut 16 has one end (its upstream end) connected to one of the positioning struts 14.
  • Each filter strut has a second end, a downstream end, held at a central portion of the vascular lumen by a frangible connector 18.
  • the arrows in FIG. 1 show the direction of blood flow.
  • the positioning struts 14 are composed of a continuous strand of nitinol or stainless steel formed in a zig-zag pattern.
  • the upstream end 14e of the positioning struts 14 are connected to the upstream ends of the filter struts 16.
  • the ends of two filter struts 16 are connected.
  • all of the struts 14 and 16 can be cut out of (by known laser techniques) a single sheet of material, which can be for example stainless steel or nitinol .
  • FIG. 3 illustrates an intermediate stage in the fabrication of the filter 10.
  • the set of struts 14 and 16, as well as the barbs 20, are cut from a single sheet of material .
  • both sets of struts; the filter struts 16, as well as the positioning struts 14, will define a cylindrical envelope.
  • each of the filter struts 16 has an eye 24, as shown in FIG. 3A.
  • a flexible cord 18 (which can be made of nylon or surgical thread) is threaded to pull the downstream ends of the filter struts 16 into the central position shown in FIGs. 1 and 2.
  • the struts 16 are made of material having resilience so that they are under tension when held in the central position by the connector 18.
  • the connector 18 can be cut, which will cause each of the filter struts 16 to spring back against the wall and to assume a position in essentially the same cylindrical envelope as are the positioning struts 14. In this fashion, the filter function can be disabled without having to remove the filter from the patient.
  • Each of the downstream ends of each of the filter struts 16 has its own eye 24 and is independent of the downstream end of any other filter strut 16.
  • each strut 16 will flex radially outward against the inner surface of the vascular wall 12.
  • the thread like connector 18 provides an open zone 26 at the center of the vascular lumen. This minimizes trapping clots smaller than the size of the opening 26. Accordingly, the filter 10 can be designed to catch only clots greater than a certain size; which are clots that are deemed to be of greatest danger to the patient involved.
  • the opening 26 has a diameter of approximately three millimeters (3mm) .
  • this central opening 26 is the area where the blood flow is the fastest. The flow will tend to dissolve blood clots caught by the struts 16. Thus the filter 10 will catch blood clots in a fashion that minimizes the risk of blocking the flow of the patient's blood.
  • the filter struts 16 shown have a particular curved configuration as illustrated in FIG. 3D. This provides the partially overlapping arrangement shown in FIG. 2 and is presently preferred to provide optimum filter coverage for the number of struts involved. However, the shape of the filter struts 16 can be different than as shown. Experimentation might show optimization of strut configuration as a function of vascular diameter.
  • the set of positioning struts 14 provide a transmission of force on the filter struts 16 that resists any tendency of the set of filter struts 16 to tilt over to one side.
  • the set of positioning struts 14 provides a centering function for the set of filter struts 16.
  • each of the struts 14 and 16 has a diameter of approximately nine mils (0.009 inches) .
  • each of the positioning struts 14 is three centimeters and each of the filter struts 16 is approximately four centimeters.
  • the angle between positioning struts 14, at both the upstream and downstream ends, is 47° in the FIG. 3 intermediate fabrication condition.
  • FIG. 4 illustrates the inactive state of the filter after the connecting element 18 has been cut.
  • FIG. 4 shows the struts 16 parked against the wall of the lumen 12.

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
EP03718415A 2002-05-01 2003-04-16 Blutgerinnselfilter Withdrawn EP1501459A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/138,152 US6881218B2 (en) 2002-05-01 2002-05-01 Blood clot filter
US138152 2002-05-01
PCT/US2003/011695 WO2003092537A2 (en) 2002-05-01 2003-04-16 Blood clot filter

Publications (2)

Publication Number Publication Date
EP1501459A2 EP1501459A2 (de) 2005-02-02
EP1501459A4 true EP1501459A4 (de) 2007-03-28

Family

ID=29269266

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03718415A Withdrawn EP1501459A4 (de) 2002-05-01 2003-04-16 Blutgerinnselfilter

Country Status (4)

Country Link
US (1) US6881218B2 (de)
EP (1) EP1501459A4 (de)
JP (1) JP2005523767A (de)
WO (1) WO2003092537A2 (de)

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JP2005523767A (ja) 2005-08-11
EP1501459A2 (de) 2005-02-02
US20030208253A1 (en) 2003-11-06
US6881218B2 (en) 2005-04-19
WO2003092537A2 (en) 2003-11-13
WO2003092537A3 (en) 2003-12-11

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