EP1458694A4 - Therapeutische verbindungen zur behandlung von dyslipidämischen zuständen - Google Patents

Therapeutische verbindungen zur behandlung von dyslipidämischen zuständen

Info

Publication number
EP1458694A4
EP1458694A4 EP02795892A EP02795892A EP1458694A4 EP 1458694 A4 EP1458694 A4 EP 1458694A4 EP 02795892 A EP02795892 A EP 02795892A EP 02795892 A EP02795892 A EP 02795892A EP 1458694 A4 EP1458694 A4 EP 1458694A4
Authority
EP
European Patent Office
Prior art keywords
therapeutic compounds
dyslipidemic conditions
treating dyslipidemic
treating
conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02795892A
Other languages
English (en)
French (fr)
Other versions
EP1458694A2 (de
Inventor
A Brian Jones
Alan D Adams
Bruno Tse
Shaei Y Huang
Ahren Green
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1458694A2 publication Critical patent/EP1458694A2/de
Publication of EP1458694A4 publication Critical patent/EP1458694A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
EP02795892A 2001-12-20 2002-12-16 Therapeutische verbindungen zur behandlung von dyslipidämischen zuständen Withdrawn EP1458694A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34255601P 2001-12-20 2001-12-20
US342556P 2001-12-20
PCT/US2002/040236 WO2003053352A2 (en) 2001-12-20 2002-12-16 Therapeutic compounds for treating dyslipidemic conditions

Publications (2)

Publication Number Publication Date
EP1458694A2 EP1458694A2 (de) 2004-09-22
EP1458694A4 true EP1458694A4 (de) 2005-12-14

Family

ID=23342338

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02795892A Withdrawn EP1458694A4 (de) 2001-12-20 2002-12-16 Therapeutische verbindungen zur behandlung von dyslipidämischen zuständen

Country Status (5)

Country Link
EP (1) EP1458694A4 (de)
JP (1) JP2005519042A (de)
AU (1) AU2002360620A1 (de)
CA (1) CA2470591A1 (de)
WO (1) WO2003053352A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2392568A1 (en) * 1999-12-13 2001-06-14 Merck & Co., Inc. Method for the prevention and/or treatment of atherosclerosis
EP1534696A4 (de) 2002-07-25 2010-04-07 Merck Sharp & Dohme Therapeutische verbindungen zur behandlung von dyslipidümieleiden
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
US20080125403A1 (en) 2004-04-02 2008-05-29 Merck & Co., Inc. Method of Treating Men with Metabolic and Anthropometric Disorders
KR101021828B1 (ko) 2004-10-27 2011-03-17 다이이찌 산쿄 가부시키가이샤 2 이상의 치환기를 갖는 벤젠 화합물
KR20070086194A (ko) 2004-12-14 2007-08-27 사노피-아벤티스 도이칠란트 게엠베하 대사 증후군 치료용 약제를 제조하기 위한 치환된사이클로프로판산 유도체의 용도
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
CA2811145A1 (en) 2010-09-07 2012-03-15 Snu R&Db Foundation Sesterterpene compound and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997028137A1 (en) * 1996-02-02 1997-08-07 Merck & Co., Inc. Heterocyclic derivatives as antidiabetic and antiobesity agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997028137A1 (en) * 1996-02-02 1997-08-07 Merck & Co., Inc. Heterocyclic derivatives as antidiabetic and antiobesity agents

Also Published As

Publication number Publication date
AU2002360620A1 (en) 2003-07-09
WO2003053352A2 (en) 2003-07-03
JP2005519042A (ja) 2005-06-30
EP1458694A2 (de) 2004-09-22
CA2470591A1 (en) 2003-07-03
WO2003053352A3 (en) 2003-11-20

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040720

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SI SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO

A4 Supplementary search report drawn up and despatched

Effective date: 20051028

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61P 9/10 B

Ipc: 7A 61P 3/06 B

Ipc: 7A 61K 31/42 B

Ipc: 7C 07D 261/20 A

17Q First examination report despatched

Effective date: 20061004

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070425