EP1448763A4 - Characterization and isolation of subsets of human embryonic stem cells (hes) and cells associated or derived therefrom - Google Patents
Characterization and isolation of subsets of human embryonic stem cells (hes) and cells associated or derived therefromInfo
- Publication number
- EP1448763A4 EP1448763A4 EP02774172A EP02774172A EP1448763A4 EP 1448763 A4 EP1448763 A4 EP 1448763A4 EP 02774172 A EP02774172 A EP 02774172A EP 02774172 A EP02774172 A EP 02774172A EP 1448763 A4 EP1448763 A4 EP 1448763A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- hes
- subsets
- characterization
- isolation
- embryonic stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPR878101 | 2001-11-09 | ||
AUPR8781A AUPR878101A0 (en) | 2001-11-09 | 2001-11-09 | Characterization and isolation of subsets of human embryonic stem cellss (HES) and cells associated or derived therefrom |
AUPS1129A AUPS112902A0 (en) | 2002-03-15 | 2002-03-15 | Characterisation and isolation of subsets of human embryonic stem cells and progenitor cells derived therefrom (2) |
AUPS112902 | 2002-03-15 | ||
PCT/AU2002/001534 WO2003040355A1 (en) | 2001-11-09 | 2002-11-11 | Characterization and isolation of subsets of human embryonic stem cells (hes) and cells associated or derived therefrom |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1448763A1 EP1448763A1 (en) | 2004-08-25 |
EP1448763A4 true EP1448763A4 (en) | 2006-11-29 |
Family
ID=25646839
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02774172A Withdrawn EP1448763A4 (en) | 2001-11-09 | 2002-11-11 | Characterization and isolation of subsets of human embryonic stem cells (hes) and cells associated or derived therefrom |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1448763A4 (en) |
CA (1) | CA2466342A1 (en) |
GB (2) | GB2419890A (en) |
WO (1) | WO2003040355A1 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002364143B2 (en) | 2001-12-07 | 2008-02-21 | Asterias Biotherapeutics, Inc. | Islet cells from primate pluripotent stem cells |
US8119774B2 (en) | 2003-10-09 | 2012-02-21 | Martin Pera | Cell marker for hepatic and pancreatic stem cells and progenitor cells |
US7585672B2 (en) * | 2004-04-01 | 2009-09-08 | Wisconsin Alumni Research Foundation | Differentiation of stem cells to endoderm and pancreatic lineage |
WO2006084314A1 (en) * | 2005-02-09 | 2006-08-17 | Australian Stem Cell Centre Limited | Stem cell populations and classification system |
JP2009514509A (en) * | 2005-10-17 | 2009-04-09 | アカデミア シニカ | Lung stem cells and related methods and kits |
WO2007149182A2 (en) | 2006-06-19 | 2007-12-27 | Geron Corporation | Differentiation and enrichment of islet-like cells from human pluripotent stem cells |
CA2766164A1 (en) * | 2009-06-25 | 2010-12-29 | Geron Corporation | Differentiated pluripotent stem cell progeny depleted of extraneous phenotypes |
EP2852617B1 (en) * | 2012-05-22 | 2018-12-12 | Life Technologies AS | Recombinant antibody compositions and methods of use thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1149898A2 (en) * | 1993-12-23 | 2001-10-31 | Infigen, Inc. | Embryonic stem cells as nuclear donors and nuclear transfer techniques to produce chimeric and transgenic animals |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU709010B2 (en) * | 1995-08-25 | 1999-08-19 | Lifecell Corporation | Reconstituted skin |
IL142748A0 (en) * | 1998-11-09 | 2002-03-10 | Univ Monash | Embryonic stem cells |
JP4889902B2 (en) * | 2000-03-14 | 2012-03-07 | イーエス・セル・インターナショナル・プライヴェート・リミテッド | Method for producing human neural progenitor cells from human embryonic stem (hES) cells, method for producing neurons using the method, method for producing oligodendrocytes or astrocytes |
WO2001072970A2 (en) * | 2000-03-28 | 2001-10-04 | University Of Iowa Research Foundation | Methods to prepare and use epidermal stem cells |
JP4795616B2 (en) * | 2000-06-20 | 2011-10-19 | イーエス・セル・インターナショナル・プライヴェート・リミテッド | Method for controlling differentiation of embryonic stem cells by culturing ES cells in the presence of a BMP-2 pathway antagonist |
-
2002
- 2002-11-11 GB GB0602441A patent/GB2419890A/en not_active Withdrawn
- 2002-11-11 WO PCT/AU2002/001534 patent/WO2003040355A1/en not_active Application Discontinuation
- 2002-11-11 GB GB0412528A patent/GB2398079B/en not_active Expired - Fee Related
- 2002-11-11 EP EP02774172A patent/EP1448763A4/en not_active Withdrawn
- 2002-11-11 CA CA002466342A patent/CA2466342A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1149898A2 (en) * | 1993-12-23 | 2001-10-31 | Infigen, Inc. | Embryonic stem cells as nuclear donors and nuclear transfer techniques to produce chimeric and transgenic animals |
Non-Patent Citations (7)
Title |
---|
KIRKLAND SUSAN C ET AL: "Collagen IV synthesis is restricted to the enteroendocrine pathway during multilineage differentiation of human colorectal epithelial stem cells", JOURNAL OF CELL SCIENCE, vol. 114, no. 11, June 2001 (2001-06-01), pages 2055 - 2064, XP002401763, ISSN: 0021-9533 * |
KOIZUMI N ET AL: "Cultivated corneal epithelial stem cell transplantation in ocular surface disorders", OPHTHALMOLOGY, J. B. LIPPINCOTT CO., PHILADELPHIA, PA, US, vol. 108, no. 9, September 2001 (2001-09-01), pages 1569 - 1574, XP002988711, ISSN: 0161-6420 * |
NIWA HITOSHI ET AL: "Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells", NATURE GENETICS, NATURE AMERICA, NEW YORK, US, vol. 24, no. 4, April 2000 (2000-04-01), pages 372 - 376, XP002155942, ISSN: 1061-4036 * |
REUBINOFF BENJAMIN E ET AL: "Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro", NATURE BIOTECHNOLOGY, NATURE PUB. CO, NEW YORK, NY, US, vol. 18, no. 4, April 2000 (2000-04-01), pages 399 - 404, XP002195338, ISSN: 1087-0156 * |
SCHULDINER MAYA ET AL: "Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 97, no. 21, 10 October 2000 (2000-10-10), pages 11307 - 11312, XP002184277, ISSN: 0027-8424 * |
See also references of WO03040355A1 * |
THOMSON J A ET AL: "EMBRYONIC STEM CELL LINES DERIVED FROM HUMAN BLASTOCYSTS", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 282, 6 November 1998 (1998-11-06), pages 1145 - 1147, XP002121340, ISSN: 0036-8075 * |
Also Published As
Publication number | Publication date |
---|---|
WO2003040355A1 (en) | 2003-05-15 |
GB0412528D0 (en) | 2004-07-07 |
GB2398079A (en) | 2004-08-11 |
GB2419890A (en) | 2006-05-10 |
GB2398079B (en) | 2006-05-31 |
GB0602441D0 (en) | 2006-03-22 |
CA2466342A1 (en) | 2003-05-15 |
EP1448763A1 (en) | 2004-08-25 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20040528 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR |
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AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20061102 |
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17Q | First examination report despatched |
Effective date: 20070221 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20081202 |