EP1435912A4 - Novel stable crystal form of n-trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine and process of preparation - Google Patents

Novel stable crystal form of n-trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine and process of preparation

Info

Publication number
EP1435912A4
EP1435912A4 EP01978760A EP01978760A EP1435912A4 EP 1435912 A4 EP1435912 A4 EP 1435912A4 EP 01978760 A EP01978760 A EP 01978760A EP 01978760 A EP01978760 A EP 01978760A EP 1435912 A4 EP1435912 A4 EP 1435912A4
Authority
EP
European Patent Office
Prior art keywords
phenylalanine
trans
preparation
crystal form
stable crystal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01978760A
Other languages
German (de)
French (fr)
Other versions
EP1435912A1 (en
Inventor
Vrajesh Shah
Anurag Hitkari
Keshav Deo
Srinivasan Rengaraju
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alembic Ltd
Original Assignee
Alembic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IN872MU2001 external-priority patent/IN191354B/en
Application filed by Alembic Ltd filed Critical Alembic Ltd
Publication of EP1435912A1 publication Critical patent/EP1435912A1/en
Publication of EP1435912A4 publication Critical patent/EP1435912A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP01978760A 2001-09-12 2001-11-05 Novel stable crystal form of n-trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine and process of preparation Withdrawn EP1435912A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
INMU08722001 2001-09-12
IN872MU2001 IN191354B (en) 2001-09-12 2001-09-12
INMU08712001 2001-09-12
IN871MU2001 2001-09-12
PCT/IB2001/002080 WO2003022251A1 (en) 2001-09-12 2001-11-05 Novel stable crystal form of n-trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine and process of preparation

Publications (2)

Publication Number Publication Date
EP1435912A1 EP1435912A1 (en) 2004-07-14
EP1435912A4 true EP1435912A4 (en) 2005-03-30

Family

ID=26324909

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01978760A Withdrawn EP1435912A4 (en) 2001-09-12 2001-11-05 Novel stable crystal form of n-trans-4-isopropylcyclohexyl carbonyl)-d-phenylalanine and process of preparation

Country Status (2)

Country Link
EP (1) EP1435912A4 (en)
WO (1) WO2003022251A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1304366C (en) 2002-04-15 2007-03-14 诺瓦提斯公司 Crystal forms of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine
US6861553B2 (en) 2002-07-03 2005-03-01 Teva Pharmaceuticals Industries Ltd. Process for preparing nateglinide and intermediates thereof
US7420084B2 (en) 2002-07-18 2008-09-02 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7534913B2 (en) 2002-07-18 2009-05-19 Teva Pharmaceutica Industries Ltd. Crystalline form of nateglinide
US7358390B2 (en) 2002-07-18 2008-04-15 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7148376B2 (en) 2002-07-18 2006-12-12 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
JP2006511614A (en) * 2002-07-18 2006-04-06 テバ ファーマシューティカル インダストリーズ リミティド Polymorphic shape of nateglinide
WO2004020396A1 (en) * 2002-08-28 2004-03-11 Dr. Reddy's Laboratories Limited Crystalline form of nateglinide and process for preparation thereof
US20060004102A1 (en) * 2004-05-07 2006-01-05 Shlomit Wizel Polymorphic forms of nateglinide

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0526171A2 (en) * 1991-07-30 1993-02-03 Ajinomoto Co., Inc. Crystals of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine and methods for preparing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5463116A (en) * 1991-07-30 1995-10-31 Ajinomoto Co., Inc. Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0526171A2 (en) * 1991-07-30 1993-02-03 Ajinomoto Co., Inc. Crystals of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine and methods for preparing them

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; LI, GANG ET AL: "A new crystal structure in nateglinide found by X-ray powder diffraction", XP002315303, retrieved from STN Database accession no. 2001:844448 *
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; LI, GANG ET AL: "New crystal form of nateglinide", XP000224976, retrieved from STN Database accession no. 2001:625224 *
See also references of WO03022251A1 *
YAOWU FENXI ZAZHI , 21(5), 342-344 CODEN: YFZADL; ISSN: 0254-1793, 2001 *
YAOXUE XUEBAO , 36(7), 532-534 CODEN: YHHPAL; ISSN: 0513-4870, 2001 *

Also Published As

Publication number Publication date
EP1435912A1 (en) 2004-07-14
WO2003022251A1 (en) 2003-03-20

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