EP1418919A2 - Verwendung von 5-fluorouracil, verabreicht durch inotophorese, als hemmer der zellproliferation im auge, der bulbären und palpebralen konjunktiva, dem augenlid, dem periorbitalen geweben und der haut - Google Patents

Verwendung von 5-fluorouracil, verabreicht durch inotophorese, als hemmer der zellproliferation im auge, der bulbären und palpebralen konjunktiva, dem augenlid, dem periorbitalen geweben und der haut

Info

Publication number
EP1418919A2
EP1418919A2 EP02747054A EP02747054A EP1418919A2 EP 1418919 A2 EP1418919 A2 EP 1418919A2 EP 02747054 A EP02747054 A EP 02747054A EP 02747054 A EP02747054 A EP 02747054A EP 1418919 A2 EP1418919 A2 EP 1418919A2
Authority
EP
European Patent Office
Prior art keywords
living subject
based medicament
ocular
approximately
uracil based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02747054A
Other languages
English (en)
French (fr)
Other versions
EP1418919A4 (de
Inventor
Stephen Warren
Steven Hamilton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iomed LLC
Original Assignee
Iomed LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iomed LLC filed Critical Iomed LLC
Publication of EP1418919A2 publication Critical patent/EP1418919A2/de
Publication of EP1418919A4 publication Critical patent/EP1418919A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
EP02747054A 2001-07-20 2002-07-19 Verwendung von 5-fluorouracil, verabreicht durch inotophorese, als hemmer der zellproliferation im auge, der bulbären und palpebralen konjunktiva, dem augenlid, dem periorbitalen geweben und der haut Withdrawn EP1418919A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30678801P 2001-07-20 2001-07-20
US306788P 2001-07-20
PCT/US2002/022860 WO2003007798A2 (en) 2001-07-20 2002-07-19 Ophthalmic use of 5 fluorourcil

Publications (2)

Publication Number Publication Date
EP1418919A2 true EP1418919A2 (de) 2004-05-19
EP1418919A4 EP1418919A4 (de) 2007-06-13

Family

ID=23186840

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02747054A Withdrawn EP1418919A4 (de) 2001-07-20 2002-07-19 Verwendung von 5-fluorouracil, verabreicht durch inotophorese, als hemmer der zellproliferation im auge, der bulbären und palpebralen konjunktiva, dem augenlid, dem periorbitalen geweben und der haut

Country Status (4)

Country Link
EP (1) EP1418919A4 (de)
JP (1) JP2004535462A (de)
AU (1) AU2002316724A1 (de)
WO (1) WO2003007798A2 (de)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0549702A (ja) * 1991-08-28 1993-03-02 Teijin Ltd イオントフオレシス用装置
US5298017A (en) * 1992-12-29 1994-03-29 Alza Corporation Layered electrotransport drug delivery system
EP0927560A1 (de) * 1998-01-05 1999-07-07 Optisinvest Vorrichtung zur intraokularen Übertragung von aktiven Wirkstoffen durch Iontophorese
WO1999040967A1 (en) * 1998-02-13 1999-08-19 Hadasit Medical Research Services & Development Company Ltd. A device for iontophoretic administration of drugs
WO2000051620A1 (en) * 1999-03-02 2000-09-08 Vitreo-Retinal Technologies, Inc. Agents for intravitreal administration to treat or prevent disorders of the eye
WO2001091853A1 (en) * 2000-05-31 2001-12-06 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery device
WO2003007961A1 (en) * 2001-07-20 2003-01-30 Iomed, Inc. Methods for treating neoplastic, angiogenic, fibroplastic, and/or immunosuppresive ocular irregularities via administration of methotrexate based medicaments, and ocular iontophoretic devices for delivering methotrexate based medicaments

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245759B1 (en) * 1999-03-11 2001-06-12 Merck & Co., Inc. Tyrosine kinase inhibitors

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0549702A (ja) * 1991-08-28 1993-03-02 Teijin Ltd イオントフオレシス用装置
US5298017A (en) * 1992-12-29 1994-03-29 Alza Corporation Layered electrotransport drug delivery system
EP0927560A1 (de) * 1998-01-05 1999-07-07 Optisinvest Vorrichtung zur intraokularen Übertragung von aktiven Wirkstoffen durch Iontophorese
WO1999040967A1 (en) * 1998-02-13 1999-08-19 Hadasit Medical Research Services & Development Company Ltd. A device for iontophoretic administration of drugs
WO2000051620A1 (en) * 1999-03-02 2000-09-08 Vitreo-Retinal Technologies, Inc. Agents for intravitreal administration to treat or prevent disorders of the eye
WO2001091853A1 (en) * 2000-05-31 2001-12-06 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery device
WO2003007961A1 (en) * 2001-07-20 2003-01-30 Iomed, Inc. Methods for treating neoplastic, angiogenic, fibroplastic, and/or immunosuppresive ocular irregularities via administration of methotrexate based medicaments, and ocular iontophoretic devices for delivering methotrexate based medicaments

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO03007798A2 *

Also Published As

Publication number Publication date
WO2003007798A2 (en) 2003-01-30
WO2003007798A3 (en) 2003-06-19
EP1418919A4 (de) 2007-06-13
AU2002316724A1 (en) 2003-03-03
JP2004535462A (ja) 2004-11-25

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