EP1349961A4 - Verfahren zur bestimmung der biologischen effekte von verbindungen auf die genexpression - Google Patents
Verfahren zur bestimmung der biologischen effekte von verbindungen auf die genexpressionInfo
- Publication number
- EP1349961A4 EP1349961A4 EP01992034A EP01992034A EP1349961A4 EP 1349961 A4 EP1349961 A4 EP 1349961A4 EP 01992034 A EP01992034 A EP 01992034A EP 01992034 A EP01992034 A EP 01992034A EP 1349961 A4 EP1349961 A4 EP 1349961A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compounds
- determining
- methods
- gene expression
- biological effects
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24833900P | 2000-11-13 | 2000-11-13 | |
US248339P | 2000-11-13 | ||
PCT/US2001/046927 WO2002038734A2 (en) | 2000-11-13 | 2001-11-09 | Methods for determining the biological effects of compounds on gene expression |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1349961A2 EP1349961A2 (de) | 2003-10-08 |
EP1349961A4 true EP1349961A4 (de) | 2005-01-26 |
Family
ID=22938682
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01992034A Withdrawn EP1349961A4 (de) | 2000-11-13 | 2001-11-09 | Verfahren zur bestimmung der biologischen effekte von verbindungen auf die genexpression |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1349961A4 (de) |
AU (1) | AU2002232510A1 (de) |
CA (1) | CA2431047A1 (de) |
WO (1) | WO2002038734A2 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040058356A1 (en) * | 2001-03-01 | 2004-03-25 | Warren Mary E. | Methods for global profiling gene regulatory element activity |
US7981842B2 (en) | 2001-06-08 | 2011-07-19 | Panomics, Inc. | Method for detecting transcription factor-protein interactions |
WO2002101351A2 (en) * | 2001-06-08 | 2002-12-19 | Panomics, Inc. | Method for detecting transcription factor-protein interactions |
AU2019239084A1 (en) * | 2018-03-23 | 2020-11-05 | Massachusetts Institute Of Technology | Methods and assays for modulating gene transcription by modulating condensates |
CN108548780A (zh) * | 2018-03-30 | 2018-09-18 | 中国人民解放军第二军医大学 | 转录因子芯片试剂盒及高通量筛选靶基因转录因子的方法 |
US11493519B2 (en) | 2019-02-08 | 2022-11-08 | Dewpoint Therapeutics, Inc. | Methods of characterizing condensate-associated characteristics of compounds and uses thereof |
KR20220027845A (ko) * | 2019-05-15 | 2022-03-08 | 화이트헤드 인스티튜트 포 바이오메디칼 리서치 | 제제-축합물 상호작용을 특성화하고 이용하는 방법 |
CN114729941A (zh) | 2019-09-18 | 2022-07-08 | 露点治疗公司 | 筛选凝聚物相关特异性的方法及其用途 |
CN116801872A (zh) * | 2021-02-10 | 2023-09-22 | 上海奕拓医药科技有限责任公司 | 调节雄激素受体凝聚物的方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0620439A2 (de) * | 1993-04-16 | 1994-10-19 | Roche Diagnostics GmbH | Verfahren zur Bestimmung der Bindung von Transkriptionsfaktoren an Nukleinsäuren |
US5821053A (en) * | 1995-02-10 | 1998-10-13 | Center For Blood Research, Inc. | LIL-Stat DNA binding sites and methods for identifying inhibitory binding agents |
WO1999019510A1 (en) * | 1997-10-10 | 1999-04-22 | President And Fellows Of Harvard College | Surface-bound, double-stranded dna protein arrays |
US6066452A (en) * | 1997-08-06 | 2000-05-23 | Yale University | Multiplex selection technique for identifying protein-binding sites and DNA-binding proteins |
US6100035A (en) * | 1998-07-14 | 2000-08-08 | Cistem Molecular Corporation | Method of identifying cis acting nucleic acid elements |
EP1136567A1 (de) * | 2000-03-24 | 2001-09-26 | Advanced Array Technologies S.A. | Methode und Kit zum Auffinden, Nachweis und/oder Quantifizieren von Transkriptionsfaktoren |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5986055A (en) * | 1997-11-13 | 1999-11-16 | Curagen Corporation | CDK2 interactions |
-
2001
- 2001-11-09 WO PCT/US2001/046927 patent/WO2002038734A2/en not_active Application Discontinuation
- 2001-11-09 EP EP01992034A patent/EP1349961A4/de not_active Withdrawn
- 2001-11-09 CA CA002431047A patent/CA2431047A1/en not_active Abandoned
- 2001-11-09 AU AU2002232510A patent/AU2002232510A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0620439A2 (de) * | 1993-04-16 | 1994-10-19 | Roche Diagnostics GmbH | Verfahren zur Bestimmung der Bindung von Transkriptionsfaktoren an Nukleinsäuren |
US5821053A (en) * | 1995-02-10 | 1998-10-13 | Center For Blood Research, Inc. | LIL-Stat DNA binding sites and methods for identifying inhibitory binding agents |
US6066452A (en) * | 1997-08-06 | 2000-05-23 | Yale University | Multiplex selection technique for identifying protein-binding sites and DNA-binding proteins |
WO1999019510A1 (en) * | 1997-10-10 | 1999-04-22 | President And Fellows Of Harvard College | Surface-bound, double-stranded dna protein arrays |
US6100035A (en) * | 1998-07-14 | 2000-08-08 | Cistem Molecular Corporation | Method of identifying cis acting nucleic acid elements |
EP1136567A1 (de) * | 2000-03-24 | 2001-09-26 | Advanced Array Technologies S.A. | Methode und Kit zum Auffinden, Nachweis und/oder Quantifizieren von Transkriptionsfaktoren |
Non-Patent Citations (4)
Title |
---|
BULYK M L ET AL: "Quantifying DNA-protein interactions by double-stranded DNA arrays", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, vol. 17, June 1999 (1999-06-01), pages 573 - 577, XP002168458, ISSN: 1087-0156 * |
BULYK MARTHA L ET AL: "Exploring the DNA-binding specificities of zinc fingers with DNA microarrays", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 98, no. 13, 19 June 2001 (2001-06-19), pages 7158 - 7163, XP002174591, ISSN: 0027-8424 * |
DUCY P ET AL: "TWO DISTINCT OSTEOBLAST-SPECIFIC CIS-ACTING ELEMENTS CONTROL EXPRESSION OF A MOUSE OSTEOCALCIN GENE", MOLECULAR AND CELLULAR BIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, WASHINGTON, US, vol. 15, no. 4, April 1995 (1995-04-01), pages 1858 - 1869, XP001152915, ISSN: 0270-7306 * |
See also references of WO0238734A3 * |
Also Published As
Publication number | Publication date |
---|---|
EP1349961A2 (de) | 2003-10-08 |
AU2002232510A1 (en) | 2002-05-21 |
WO2002038734A2 (en) | 2002-05-16 |
CA2431047A1 (en) | 2002-05-16 |
WO2002038734A3 (en) | 2002-07-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030611 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20041209 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7C 12Q 1/68 A |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: GENPATHWAY, INC. |
|
17Q | First examination report despatched |
Effective date: 20050412 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20051025 |