EP1317322A1 - Busette - Google Patents

Busette

Info

Publication number
EP1317322A1
EP1317322A1 EP01967885A EP01967885A EP1317322A1 EP 1317322 A1 EP1317322 A1 EP 1317322A1 EP 01967885 A EP01967885 A EP 01967885A EP 01967885 A EP01967885 A EP 01967885A EP 1317322 A1 EP1317322 A1 EP 1317322A1
Authority
EP
European Patent Office
Prior art keywords
dispensing
nozzle
fluid channel
fluid
providing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01967885A
Other languages
German (de)
English (en)
Inventor
Per Ove ÖHMAN
Patrik Hollman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amic AB
Original Assignee
Amic AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amic AB filed Critical Amic AB
Publication of EP1317322A1 publication Critical patent/EP1317322A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/16—Production of nozzles
    • B41J2/162—Manufacturing of the nozzle plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B1/00—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means
    • B05B1/02—Nozzles, spray heads or other outlets, with or without auxiliary devices such as valves, heating means designed to produce a jet, spray, or other discharge of particular shape or nature, e.g. in single drops, or having an outlet of particular shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/14—Structure thereof only for on-demand ink jet heads
    • B41J2/1433—Structure of nozzle plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/16—Production of nozzles
    • B41J2/1621—Manufacturing processes
    • B41J2/1637—Manufacturing processes molding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/16—Production of nozzles
    • B41J2/1621—Manufacturing processes
    • B41J2/164—Manufacturing processes thin film formation
    • B41J2/1643—Manufacturing processes thin film formation thin film formation by plating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/135—Nozzles
    • B41J2/16—Production of nozzles
    • B41J2/1621—Manufacturing processes
    • B41J2/164—Manufacturing processes thin film formation
    • B41J2/1646—Manufacturing processes thin film formation thin film formation by sputtering

Definitions

  • the present invention relates to a dispensing nozzle for dispensing minute fluid volumes, a method for making the dispensing nozzle, a pipette tip comprising the dispensing nozzle, a pipette comprising the pipette tip, and a method for dispensing a fluid by means of an inventive pipette member.
  • One such technique consists in using pipettes having a space for holding a fluid into which a desired amount of fluid is introduced using an adjustable piston pump or a similar device, by means of which the fluid is then pumped out into the desired location, such as an analysis well on a micro-titre plate.
  • a conventional pipette tip is comprised of a conical plastic body having an internal volume that is filled with the fluid to be dispensed. Since the opening of the pipette tip is made in the plastic material of the pipette tip, it is not as well defined as it would need to be in order for achieving the desired degree of accuracy. Further, if the plastic material has a relatively low wetting angle , the deviation can be quite important, especially considering dispensing of volumes of e.g. a few micro-litres. Some of the fluid may adhere to the pipette tip, and since the volume is very small, this could mean that as much as half the volume to be dispensed could adhere to the area of the tip around the opening.
  • a related problem is that of delivery precision. Since the volumes are very small, the surface tension of fluid adhering to the pipette tip may cause the dispensed fluid to deviate from the desired direction of dispensing. This may be as serious a problem as the volume inaccuracy. Furthermore, the conventional techniques for manufacturing nozzles suitable for dispensing minute volumes of fluid have a serious drawback, in that the plating techniques used only allow for the use of a relatively limited number of materials. This has consequences for numerous applications where it is necessary to provide some areas of the nozzle with certain surface properties, in that such characteristics have to be provided separately. Such techniques are further relatively expensive.
  • the nozzles are damaged by being contacted by the paper being printed. If the outlet opening of the nozzle is damaged by contact with the paper, this may render the nozzle unfit for use, and replacement of the nozzle is required to secure a good function of the printer device.
  • a dispensing nozzle as defined in the characterising part of claim 1.
  • a dispensing member for a pipette as defined in the characterising part of claim 24.
  • a dispenser as defined in the characterising part of claim 25.
  • Fig. 1 is a perspective view of dispensing means for a pipette
  • Fig. 2a is a plan view of a nozzle for the dispensing means in fig. 1 ;
  • Fig. 2b is a cross section of the nozzle in fig. 1 along the line II-II;
  • Fig. 3a and 3b show an alternative design of a nozzle according to the present invention in a plan view and cross section, respectively;
  • Fig. 4a and 4b show two alternative designs for a nozzle according to the present invention in plan view and cross section, respectively;
  • Fig. 5a is a perspective view of a mould according to one aspect of the present invention.
  • Fig. 5b is a perspective view of a mould according to second embodiment of this aspect of the present invention.
  • a dispensing device for use as a tip for a pipette, generally designated by the reference numeral 10.
  • Said device comprises a body portion 11 having a first end 12 and a second end 13, and an internal conduit 14 having a first opening 14a at the first end 12 of the body portion 11, and a second opening 14b at the second end 13 of the body portion 11.
  • the first end 12 comprises a structure allowing the dispensing means to be mounted to a pipette (not shown), such as conventional snap lock means or the like. Examples of this structure, including the pipette are not shown in the figures, since this is well known to the artisan.
  • the first opening 14a of the internal conduit provides fluid communication with a channel of the pipette when mounted thereon, and the second opening 14b is open to the outside when mounted on the pipette.
  • the second opening 14b of the second end 13 of the body portion includes means for mounting a dispensing nozzle 15 according to the present invention. This specific embodiment will be described in more detail below.
  • the dispensing nozzle 15 according to the embodiments of the present invention shown in fig. 2-4, comprises a base member 17 having the shape of a round washer, and a fluid channel 16 provided centrally in the washer.
  • the fluid channel 16 has a diameter ranging from approximately 20 ⁇ m and upwards, for instance up to approximately 200 ⁇ m.
  • the inner surface 16a of the fluid channel 16 has high wettability, so as to make a fluid which is introduced in the channel 16 adhere to the inner surface 16a thereof. Some of the surfaces surrounding the openings of the fluid channel 16 may have low wettability.
  • the bottom surface has low wettability, which is provided either by suitable selection of a material for the bottom surface having such intrinsic properties, or by a surface coating provided in a separate step.
  • One solution consists in sputtering a thin layer of silver or gold on the surface to be treated, and subsequently letting this surface react with octadecanthiol dissolved in ethanol. This treatment forms a thin layer of molecules on the silver or gold surface that gives a high wetting angle for water.
  • low wettability shall be understood as a wetting angle of 90° or more for the fluid to be dispensed. Since the wettability of a surface is specific to an individual fluid, it may be necessary to provide one and the same nozzle material with different surface coating in order to obtain the same wettability for different fluids. In some applications it may be desirable to have different wetting angles on different areas of the nozzle.
  • the fluid channel itself may have a portion with low wettability, e.g. a lower portion near the outlet opening, and a portion with high wettability, e.g. in the upper portion adjacent to the inlet opening.
  • the upper and lower surfaces may both be provided with have only low wettability, or entirely high wettability, or display a combination of these properties in different zones, depending on the specific needs of the specific application.
  • the shape of the fluid channel may be varied according to certain principles.
  • the basic shape of the fluid channel which is shown in the figures, is that with a cylindrical cross section.
  • Fig. 4b such an increase is accomplished by using multiple fluid channels in one nozzle.
  • a larger volume of fluid may be dispensed with the inventive nozzle, while maintaining a high reliability in terms of non-leakage.
  • the number of fluid channels in the nozzle may of course be varied according to the needs of the specific application.
  • the fluid channel is provided in an indentation in the bottom surface of the dispensing nozzle, which is shown in fig. 6a and 6b.
  • the wall portion of the indentation forms an angle of 90° with the general extension of the nozzle. In the case of a nozzle with a high wetting angle, these 90° adds to the wetting angle of 90° or more of the material surface.
  • this design gives a nozzle with improved functionality, especially for inkjet printers, where the nozzles may be damaged by contact with the paper to be printed. Since it is very easy for the paper to get in contact with the nozzle opening, the nozzle opening being the most sensitive part, this embodiment is well suited for inkjet printer applications, or similar applications with similar environments posing the possible hazard of damage to the nozzle.
  • the fluid channel extends through a portion protruding from the bottom surface of the inventive dispensing nozzle, also shown in fig. 6a and 6b .
  • the wettability of the nozzle is improved. Should a drop of the dispensed fluid stick to the protrusion, the drop will fall off the nozzle protrusion more easily than it would, if the outlet opening of the nozzle were not arranged on a portion protruding from the general plane of the nozzle bottom surface.
  • the present invention teaches a method for manufacturing such dispensing nozzles. According to this method, dispensing nozzles having the features described above are manufactured. Moreover, the present invention also teaches the use of a moulding technique for manufacturing the dispensing nozzles. By using this technique, the choice of material is widened to include a very wide variety of e.g. polymeric materials. By choosing a polymeric material having suitable wettability properties, it is possible to obtain the desired material properties in at least some areas of the nozzle without having to use a subsequent surface treatment which is sometimes necessary with other techniques, e.g. plating techniques.
  • the mould itself may be manufactured by means of the same techniques, which are used for manufacturing substrates for plating, i.e. by curing a material by means of e.g. UV-light.
  • the UV-light is transmitted through a curing mask in which the fluid channel or channels, in the case of a nozzle having e.g. an array of very fine fluid channels, are defined as holes in the mask.
  • the curable material which is deposited on a bottom substrate, is exposed to the TJN- light through the mask, leaving the a negative form of the fluid channels cured, and the material which has not been cured is removed, leaving a fluid channel post or posts, of cured material after exposure.
  • the possible length of the fluid channel is determined by the height of the fluid channel post or posts.
  • the mould is made from silicon rubber.
  • Silicon rubber is a material with desirable properties when used to make moulds, since it is very easy to strip the moulded material from a silicon rubber mould.
  • a second mould is placed on top of the first mould with the fluid channel post (or posts in the case of producing more than one nozzle, or a nozzle having multiple openings), bearing on the fluid channel posts, and then the moulding material is introduced in a conventional way. The material is then cured, or simply allowed to cool or solidify, and the mould is removed.
  • the dispensing nozzle may be manufactured by multiple layer moulding. In this way, and by using materials with suitable characteristics, it is possible to predefine portions, especially of the fluid channel, which have different wetting angle characteristics.
  • nozzles comprising an indentation surrounding the outlet opening of the fluid channel are produced.
  • an upper mould is used having a shape corresponding to the negative shape of the indentation.
  • the moulds are then brought together to form a moulding space, aligning the negative indentation and the fluid channel post, moulding material is supplied, and is allowed to cure or simply cool or solidify.
  • the present invention also teaches a similar manufacturing technique for manufacturing nozzles having a protrusion surrounding the outlet opening of the fluid channel.
  • an upper mould is used having a shape corresponding to the negative shape of the protrusion.
  • the moulds are then brought together to form a moulding space, aligning the negative indentation and the fluid channel post, moulding material is supplied, and is allowed to cure or simply cool or solidify.
  • a mould made from a different material than silicon rubber, e.g. a metallic material or even a polymeric, or another material suitable for the specific purposes.
  • the mould may be formed by means of a method that is suited for the mould material.
  • the invention also teaches the manufacturing of nozzles by means of plating on a plating substrate. This method is similar to the novel moulding technique in terms of mould manufacturing, apart from the fact that the nozzle base member including the fluid channel, is formed by any suitable plating method in which a conductive plating substrate is used. Since plating is a well known art, for instance from SE-xxxx, no further discussion is given here.
  • mould material and moulding material it may be necessary to provide the moulding surface of the mould or the moulds with a suitable surface treatment for facilitating the stripping of the finished nozzles from the mould. This is, however, also common knowledge in the art.
  • the dispenser comprises pressure generating member which may be comprised of a diaphragm of the type found for instance in loudspeakers which is reciprocated, thus generating a pressure pulse when moving in one direction, and generating a suction pulse when moving in the other direction.
  • the pressure pulse is transmitted via a transmission fluid , e.g. air, in a pipe or hose, to a dispensing device according to the present invention and comprising the inventive dispensing nozzle, and used for providing dispensing action.
  • the pressure generating means of the dispenser performs this reciprocating motion with a predetermined frequency.
  • the forward motion of the pressure generating member is performed with a first velocity
  • the backward motion is performed with a second velocity which is lower than the first velocity. This is to ensure that no air or any other fluid with which the dispensing device or dispensing nozzle is in contact with, is sucked into the dispensing device during the return motion of the reciprocating pressure generating member.
  • the dispenser is provided with mounting means for mounting a dispensing device according to the present invention.
  • the dispenser itself may be located remote from the dispensing device comprising the nozzle. Since air or other transmission fluids are used, it is sufficient to provide a conduit communicating the dispenser according to the present invention with the dispensing device comprising the inventive nozzle for transmitting the pressure pulses generated by the dispenser. It is, however, important to make sure that pressure losses are eliminated, since this will influence the dispensed volume in a substantial way, given the very small volumes to be handled and dispensed.
  • a dispensing device in the form of a pipette tip is used in conjunction with a conventional pipette. If the normal suction function of the pipette is used for introducing the fluid to be dispensed into the fluid dispensing device, the volume introduced by means of the suction is for practical reasons preferably larger than the volume to be dispensed. Then the proper volume is then dispensed from the pipette tip. The pipette tip may then be discarded, another tip mounted to the pipette, and the procedure repeated.
  • This dispensing procedure is the conventional way of dispensing fluids by means of pipettes in most applications.
  • the objects set out initially are achieved by means of the different aspects of the present invention.
  • the principal field of application of the present invention is the biological or bio-chemical field
  • some embodiment of the present invention may be used with advantageous results in other fields of application.
  • the inventive dispensing member may be used with other dispensers than pipettes, and different materials may be used for the different embodiments of all of the aspects of the present invention.

Landscapes

  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nozzles (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

Abstract

L'invention concerne une busette (15) comprenant un élément de base (17) qui est sensiblement plat et a deux surfaces sensiblement parallèles. Cet élément de base renferme au moins un canal de fluide (16) pourvu d'un orifice d'entrée et d'un orifice de sortie. Le canal est sensiblement perpendiculaire au sens longitudinal général de l'élément de base (15). Une surface qui entoure au moins un orifice, a un grand angle de mouillabilité pour le fluide à dispenser.
EP01967885A 2000-09-15 2001-09-14 Busette Withdrawn EP1317322A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0003293A SE0003293D0 (sv) 2000-09-15 2000-09-15 Dispensing nozzle
SE0003293 2000-09-15
PCT/SE2001/001968 WO2002022275A1 (fr) 2000-09-15 2001-09-14 Busette

Publications (1)

Publication Number Publication Date
EP1317322A1 true EP1317322A1 (fr) 2003-06-11

Family

ID=20281038

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01967885A Withdrawn EP1317322A1 (fr) 2000-09-15 2001-09-14 Busette

Country Status (7)

Country Link
US (1) US20040027419A1 (fr)
EP (1) EP1317322A1 (fr)
JP (1) JP2004508193A (fr)
AU (2) AU8816801A (fr)
CA (1) CA2422112A1 (fr)
SE (1) SE0003293D0 (fr)
WO (1) WO2002022275A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005249436A (ja) * 2004-03-02 2005-09-15 Enplas Corp 液滴吐出装置及び液滴吐出装置の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3958255A (en) * 1974-12-31 1976-05-18 International Business Machines Corporation Ink jet nozzle structure
US4791436A (en) * 1987-11-17 1988-12-13 Hewlett-Packard Company Nozzle plate geometry for ink jet pens and method of manufacture
CA1329341C (fr) * 1988-10-19 1994-05-10 Rosemary Bridget Albinson Methode de deposition d'une couche adherente de fluorosilane sur un substrat, et tete d'enregistrement a jet d'encre ainsi revetue
EP0602021A2 (fr) * 1988-10-31 1994-06-15 Canon Kabushiki Kaisha Tête à jet d'encre et son procédé de fabrication, plaque à orifices d'écoulement pour cette tête et son procédé de fabrication, et appareil à jet d'encre avec tête à jet d'encre
JPH06297719A (ja) * 1993-04-16 1994-10-25 Brother Ind Ltd 液滴噴射装置及びその製造方法
JP3169037B2 (ja) * 1993-10-29 2001-05-21 セイコーエプソン株式会社 インクジェット記録ヘッドのノズルプレートの製造方法
US6447984B1 (en) * 1999-02-10 2002-09-10 Canon Kabushiki Kaisha Liquid discharge head, method of manufacture therefor and liquid discharge recording apparatus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO0222275A1 *

Also Published As

Publication number Publication date
SE0003293D0 (sv) 2000-09-15
AU2001288168B2 (en) 2006-06-08
WO2002022275A1 (fr) 2002-03-21
CA2422112A1 (fr) 2002-03-21
US20040027419A1 (en) 2004-02-12
JP2004508193A (ja) 2004-03-18
AU8816801A (en) 2002-03-26

Similar Documents

Publication Publication Date Title
CN107824229B (zh) 电动微流控液滴分配器
JP3463929B2 (ja) 体積センサのない微量分注デバイス、分注デバイス配列、および微量分注デバイスの使用用途
US4412224A (en) Method of forming an ink-jet head
EP1952896B1 (fr) Appareil de distribution de gouttelettes
US7900850B2 (en) Microdosing apparatus and method for dosed dispensing of liquids
US6550691B2 (en) Reagent dispenser head
US6326212B1 (en) Membrane dispensing head apparatus and method for dispensing liquid
WO2004099059A2 (fr) Procede et systeme de distribution precise d'un liquide
AU2001288168B2 (en) Dispensing nozzle
JP2000329771A (ja) 分注装置
CN100404121C (zh) 微型反应器
AU2001288168A1 (en) Dispensing nozzle
US6378995B1 (en) Manufacturing method of nozzle plate using silicon process and ink jet printer head applying the nozzle plate
US6530755B2 (en) Micropump
JP5524637B2 (ja) 微小液滴吐出装置
JP7123398B2 (ja) 流体エジェクタ
JP2000310645A (ja) 液体分注装置
US20220297113A1 (en) Monolithic carrier structure including fluid routing for digital dispensing
TWI448391B (zh) 產生微微射流（Ｐｉｃｏ-Ｆｌｕｉｄｉｃ）噴墨之系統與方法
CN215878519U (zh) 压电式抛弃型微流体喷射阀
RU2817562C1 (ru) Пьезоэлектрический дозатор
CN112517308B (zh) 振动网式雾化器及其制作方法
CN112517309B (zh) 用于高粘度液体雾化的网孔微结构及其制作方法
US20020127014A1 (en) Fluid dispensing method and apparatus employing piezoelectric transducer
US20040035948A1 (en) Liquid transfer device

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20030402

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20061213