EP1312676A4 - Neuartige protease gene - Google Patents
Neuartige protease geneInfo
- Publication number
- EP1312676A4 EP1312676A4 EP01956995A EP01956995A EP1312676A4 EP 1312676 A4 EP1312676 A4 EP 1312676A4 EP 01956995 A EP01956995 A EP 01956995A EP 01956995 A EP01956995 A EP 01956995A EP 1312676 A4 EP1312676 A4 EP 1312676A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- novel
- substance
- neurolysin
- protease gene
- novel protease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24016—Neurolysin (3.4.24.16)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000252503 | 2000-08-23 | ||
JP2000252503 | 2000-08-23 | ||
PCT/JP2001/007147 WO2002016610A1 (fr) | 2000-08-23 | 2001-08-21 | Nouveau gene de la protease |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1312676A1 EP1312676A1 (de) | 2003-05-21 |
EP1312676A4 true EP1312676A4 (de) | 2004-11-24 |
Family
ID=18741732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01956995A Ceased EP1312676A4 (de) | 2000-08-23 | 2001-08-21 | Neuartige protease gene |
Country Status (6)
Country | Link |
---|---|
US (2) | US20040014939A1 (de) |
EP (1) | EP1312676A4 (de) |
AU (1) | AU2001278787A1 (de) |
CA (1) | CA2420275A1 (de) |
NO (1) | NO20030809L (de) |
WO (1) | WO2002016610A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1944647B (zh) * | 2006-08-23 | 2010-05-12 | 华东师范大学 | 多巴胺受体新亚型d5b基因及编码的蛋白与应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001079509A1 (en) * | 2000-04-12 | 2001-10-25 | Lexicon Genetics Incorporated | Human metalloprotease and polynucleotides encoding the same |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6444802B1 (en) * | 1999-09-30 | 2002-09-03 | Millenium Pharmaceuticals, Inc. | Human aminopeptidase |
-
2001
- 2001-08-21 CA CA002420275A patent/CA2420275A1/en not_active Abandoned
- 2001-08-21 AU AU2001278787A patent/AU2001278787A1/en not_active Abandoned
- 2001-08-21 WO PCT/JP2001/007147 patent/WO2002016610A1/ja not_active Application Discontinuation
- 2001-08-21 EP EP01956995A patent/EP1312676A4/de not_active Ceased
- 2001-08-21 US US10/362,226 patent/US20040014939A1/en not_active Abandoned
-
2003
- 2003-02-21 NO NO20030809A patent/NO20030809L/no not_active Application Discontinuation
-
2006
- 2006-06-14 US US11/452,363 patent/US20060228362A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001079509A1 (en) * | 2000-04-12 | 2001-10-25 | Lexicon Genetics Incorporated | Human metalloprotease and polynucleotides encoding the same |
Non-Patent Citations (10)
Title |
---|
BARELLI H ET AL: "Potent inhibition of endopeptidase 24.16 and endopeptidase 24.15 by the phosphonamide peptide N-(phenylethylphosphonyl)-Gly-L-Pro-L-aminohexanoic acid", BIOCHEM J, vol. 287, 1992, pages 621 - 625, XP000571638 * |
DATABASE EMBL 11 November 1999 (1999-11-11), XP002297860, retrieved from EBI Database accession no. AB033052 * |
DATABASE EMBL 23 January 1997 (1997-01-23), XP002297859, retrieved from EBI Database accession no. SSAB174 * |
DATABASE UNIPROT 1 May 1997 (1997-05-01), XP002297858, retrieved from EBI Database accession no. P79433 * |
KATO A ET AL: "Targeting of endopeptidase 24.16 to different subcellular compartments by alternative promoter usage.", THE JOURNAL OF BIOLOGICAL CHEMISTRY. 13 JUN 1997, vol. 272, no. 24, 13 June 1997 (1997-06-13), pages 15313 - 15322, XP002297857, ISSN: 0021-9258 * |
KRAUSE DR ET AL: "Characterization and Localization of Mitochondrial Oligopeptidase (MOP) (EC 3.4.24.16) Activity in the Human Cervical Adenocarcinoma Cell Line HeLa", JOURNAL OF CELLULAR BIOCHEMISTRY, vol. 66, 1997, pages 297 - 308 * |
NAGASE T ET AL: "PREDICTION OF THE CODING SEQUENCES OF UNIDENTIFIED HUMAN GENES. XV. THE COMPLETE SEQUENCES OF 100 NEW CDNA CLONES FROM BRAIN WHICH CODE FOR LARGE PROTEINS IN VITRO", DNA RESEARCH, UNIVERSAL ACADEMY PRESS, JP, vol. 6, 1999, pages 337 - 345, XP000865804, ISSN: 1340-2838 * |
See also references of WO0216610A1 * |
SHRIMPTON C N ET AL: "Soluble neutral metallopeptidases: physiological regulators of peptide action.", JOURNAL OF PEPTIDE SCIENCE : AN OFFICIAL PUBLICATION OF THE EUROPEAN PEPTIDE SOCIETY. JUN 2000, vol. 6, no. 6, June 2000 (2000-06-01), pages 251 - 263, XP009037009, ISSN: 1075-2617 * |
VINCENT B ET AL: "PURIFICATION AND CHARACTERIZATION OF HUMAN ENDOPEPTIDASE 3.4.24.16.COMPARISON WITH THE PORCINE COUNTERPART INDICATES A UNIQUE CLEAVAGE SITE ON NEUROTENSIN", BRAIN RESEARCH, AMSTERDAM, NL, vol. 709, no. 1, 1996, pages 51 - 58, XP001010406, ISSN: 0006-8993 * |
Also Published As
Publication number | Publication date |
---|---|
NO20030809L (no) | 2003-04-14 |
AU2001278787A1 (en) | 2002-03-04 |
CA2420275A1 (en) | 2003-02-21 |
WO2002016610A1 (fr) | 2002-02-28 |
EP1312676A1 (de) | 2003-05-21 |
US20060228362A1 (en) | 2006-10-12 |
US20040014939A1 (en) | 2004-01-22 |
NO20030809D0 (no) | 2003-02-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030220 |
|
AK | Designated contracting states |
Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20041008 |
|
17Q | First examination report despatched |
Effective date: 20050103 |
|
17Q | First examination report despatched |
Effective date: 20050103 |
|
18R | Application refused |
Effective date: 20080502 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED |
|
R18R | Application refused (corrected) |
Effective date: 20080403 |