EP1311283A4 - Omega-conopeptides - Google Patents

Omega-conopeptides

Info

Publication number
EP1311283A4
EP1311283A4 EP01957214A EP01957214A EP1311283A4 EP 1311283 A4 EP1311283 A4 EP 1311283A4 EP 01957214 A EP01957214 A EP 01957214A EP 01957214 A EP01957214 A EP 01957214A EP 1311283 A4 EP1311283 A4 EP 1311283A4
Authority
EP
European Patent Office
Prior art keywords
conopeptides
omega
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01957214A
Other languages
German (de)
English (en)
Other versions
EP1311283A2 (fr
Inventor
Baldomero M Olivera
J Michael Mcintosh
Maren Watkins
James E Garrett
Ki-Joon Shon
Richard Jacobsen
Robert M Jones
G Edward Cartier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah Research Foundation UURF
Cognetix Inc
Original Assignee
University of Utah Research Foundation UURF
Cognetix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Utah Research Foundation UURF, Cognetix Inc filed Critical University of Utah Research Foundation UURF
Publication of EP1311283A2 publication Critical patent/EP1311283A2/fr
Publication of EP1311283A4 publication Critical patent/EP1311283A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP01957214A 2000-07-21 2001-07-23 Omega-conopeptides Withdrawn EP1311283A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21961600P 2000-07-21 2000-07-21
US219616P 2000-07-21
US26588801P 2001-02-05 2001-02-05
US265888P 2001-02-05
PCT/US2001/023041 WO2002007675A2 (fr) 2000-07-21 2001-07-23 Omega-conopeptides

Publications (2)

Publication Number Publication Date
EP1311283A2 EP1311283A2 (fr) 2003-05-21
EP1311283A4 true EP1311283A4 (fr) 2004-09-01

Family

ID=26914073

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01957214A Withdrawn EP1311283A4 (fr) 2000-07-21 2001-07-23 Omega-conopeptides

Country Status (5)

Country Link
EP (1) EP1311283A4 (fr)
JP (1) JP2004512025A (fr)
AU (1) AU2001278982A1 (fr)
CA (1) CA2416287A1 (fr)
WO (1) WO2002007675A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2077854B1 (fr) 2006-11-04 2013-01-23 Anygen Co., Ltd. Oméga-conotoxines
WO2011032233A1 (fr) * 2009-09-21 2011-03-24 The University Of Queensland Nouveaux peptides de conotoxine oméga
JP6977979B2 (ja) * 2015-06-09 2021-12-08 国立大学法人大阪大学 神経損傷治療又は予防用医薬

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231011A (en) * 1991-04-18 1993-07-27 University Of Utah Segregated folding determinants for small disulfide-rich peptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG50624A1 (en) * 1991-12-30 1998-07-20 Neurex Corp Methods of producing analgesia and enhancing opiate analgesia
US5591821A (en) * 1993-07-16 1997-01-07 The University Of Utah Omega-conotoxin peptides
CN1247613C (zh) * 1998-04-16 2006-03-29 昆士兰大学 新型ω－芋螺毒素肽

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231011A (en) * 1991-04-18 1993-07-27 University Of Utah Segregated folding determinants for small disulfide-rich peptides

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
BAI-SONG L ET AL: "CONOPEPTIDES FROM CONUS STRIATUS AND CONUS TEXTILE BY CDNA CLONING", PEPTIDES, ELMSFORD, US, vol. 20, 1999, pages 1139 - 1144, XP002939062, ISSN: 0196-9781 *
DATABASE EMBL [online] 1 November 1988 (1988-11-01), "Omega-conotoxin MVIIa precursor (SNX-111) (Zicotonide).", XP002269558, retrieved from EBI Database accession no. P05484 *
DATABASE EMBL [online] 21 July 1986 (1986-07-21), "Omega-conotoxin GVIA precursor (Shaker peptide) (SNX-124)", XP002269557, retrieved from EBI Database accession no. P01522 *
HOGG R C ET AL: "Single amino acid substitutions in alpha-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor.", THE JOURNAL OF BIOLOGICAL CHEMISTRY. UNITED STATES 17 DEC 1999, vol. 274, no. 51, 17 December 1999 (1999-12-17), pages 36559 - 36564, XP002269307, ISSN: 0021-9258 *
JACOBSEN R B ET AL: "CRITICAL RESIDUES INFLUENCE THE AFFINITY AND SELECTIVITY OF ALPHA-CONOTOXIN MI FOR NICOTINIC ACETYLCHOLINE RECEPTORS", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 38, no. 40, 1999, pages 13310 - 13315, XP002948684, ISSN: 0006-2960 *
NADASDI L ET AL: "structure-activity analysis of a conus peptide blocker of N-type neuronal calcium channels", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 34, no. 25, 27 June 1995 (1995-06-27), pages 8076 - 8081, XP002965816, ISSN: 0006-2960 *
NIELSEN K J ET AL: "A CONSENSUS STRUCTURE FOR OMEGA-CONOTOXINS WITH DIFFERENT SELECTIVITIES FOR VOLTAGE-SENSITIVE CALCIUM CHANNEL SYBTYPES: COMPARISON OF MVIIA, SVIB AND SNX-202", JOURNAL OF MOLECULAR BIOLOGY, LONDON, GB, vol. 263, 1996, pages 297 - 310, XP000986598, ISSN: 0022-2836 *
SATO K ET AL: "Binding of chimeric analogs of [omega ]-conotoxin MVIIA and MVIIC to the N- and P/Q-type calcium channels", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 414, no. 2, 8 September 1997 (1997-09-08), pages 480 - 484, XP004366374, ISSN: 0014-5793 *
See also references of WO0207675A3 *

Also Published As

Publication number Publication date
EP1311283A2 (fr) 2003-05-21
WO2002007675A3 (fr) 2003-03-06
CA2416287A1 (fr) 2002-01-31
AU2001278982A1 (en) 2002-02-05
JP2004512025A (ja) 2004-04-22
WO2002007675A2 (fr) 2002-01-31

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20030217

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CARTIER, G., EDWARD

Inventor name: JONES, ROBERT, M.

Inventor name: JACOBSEN, RICHARD

Inventor name: SHON, KI-JOON

Inventor name: GARRETT, JAMES, E.

Inventor name: WATKINS, MAREN

Inventor name: MCINTOSH, J., MICHAEL

Inventor name: OLIVERA, BALDOMERO, M.

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CARTIER, G., EDWARD

Inventor name: JONES, ROBERT, M.

Inventor name: JACOBSEN, RICHARD

Inventor name: SHON, KI-JOON

Inventor name: GARRETT, JAMES, E.

Inventor name: WATKINS, MAREN

Inventor name: MCINTOSH, J., MICHAEL

Inventor name: OLIVERA, BALDOMERO, M.

RIN1 Information on inventor provided before grant (corrected)

Inventor name: CARTIER, G., EDWARD

Inventor name: JONES, ROBERT, M.

Inventor name: JACOBSEN, RICHARD

Inventor name: SHON, KI-JOON

Inventor name: GARRETT, JAMES, E.

Inventor name: WATKINS, MAREN

Inventor name: MCINTOSH, J., MICHAEL

Inventor name: OLIVERA, BALDOMERO, M.

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61K 38/17 B

Ipc: 7C 07K 14/435 A

A4 Supplementary search report drawn up and despatched

Effective date: 20040719

17Q First examination report despatched

Effective date: 20060906

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20070117