EP1311282A4 - Hochaffine integrinpolypeptide und deren verwendung - Google Patents

Hochaffine integrinpolypeptide und deren verwendung

Info

Publication number
EP1311282A4
EP1311282A4 EP01965844A EP01965844A EP1311282A4 EP 1311282 A4 EP1311282 A4 EP 1311282A4 EP 01965844 A EP01965844 A EP 01965844A EP 01965844 A EP01965844 A EP 01965844A EP 1311282 A4 EP1311282 A4 EP 1311282A4
Authority
EP
European Patent Office
Prior art keywords
high affinity
integrin polypeptides
affinity integrin
polypeptides
integrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01965844A
Other languages
English (en)
French (fr)
Other versions
EP1311282A1 (de
Inventor
Amin M Arnaout
Rui Li
Jian-Ping Xiong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/758,493 external-priority patent/US7064180B2/en
Priority claimed from US09/805,354 external-priority patent/US7153944B2/en
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of EP1311282A1 publication Critical patent/EP1311282A1/de
Publication of EP1311282A4 publication Critical patent/EP1311282A4/de
Withdrawn legal-status Critical Current

Links

EP01965844A 2000-07-31 2001-07-31 Hochaffine integrinpolypeptide und deren verwendung Withdrawn EP1311282A4 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US22195000P 2000-07-31 2000-07-31
US221950P 2000-07-31
US09/758,493 US7064180B2 (en) 2000-07-31 2001-01-11 High affinity integrin polypeptides and uses thereof
US758493 2001-01-11
US09/805,354 US7153944B2 (en) 2000-07-31 2001-03-13 High affinity integrin polypeptides and uses thereof
US805354 2001-03-13
PCT/US2001/023957 WO2002009737A1 (en) 2000-07-31 2001-07-31 High affinity integrin polypeptides and uses thereof

Publications (2)

Publication Number Publication Date
EP1311282A1 EP1311282A1 (de) 2003-05-21
EP1311282A4 true EP1311282A4 (de) 2005-07-13

Family

ID=56290175

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01965844A Withdrawn EP1311282A4 (de) 2000-07-31 2001-07-31 Hochaffine integrinpolypeptide und deren verwendung

Country Status (5)

Country Link
EP (1) EP1311282A4 (de)
JP (1) JP2004504827A (de)
AU (1) AU2001286403A1 (de)
CA (1) CA2418120A1 (de)
MX (1) MXPA03000981A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9657103B2 (en) 2012-05-02 2017-05-23 New York University Methods of treating and preventing Staphylococcus aureus infections and associated conditions

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059878A2 (en) * 1999-04-02 2000-10-12 Icos Corporation INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF
WO2000060355A2 (en) * 1999-04-02 2000-10-12 Icos Corporation Lfa-1 regulatory binding site and uses thereof
WO2002004521A2 (en) * 2000-07-07 2002-01-17 California Institute Of Technology Proteins with integrin-like activity
WO2002031511A2 (en) * 2000-10-12 2002-04-18 Icos Corporation Modulation of ligand binding/enzymatic activity of alpha beta proteins
WO2002072030A2 (en) * 2001-03-13 2002-09-19 The General Hospital Corporation High affinity integrin polypeptides and uses thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000059878A2 (en) * 1999-04-02 2000-10-12 Icos Corporation INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF
WO2000060355A2 (en) * 1999-04-02 2000-10-12 Icos Corporation Lfa-1 regulatory binding site and uses thereof
WO2002004521A2 (en) * 2000-07-07 2002-01-17 California Institute Of Technology Proteins with integrin-like activity
WO2002031511A2 (en) * 2000-10-12 2002-04-18 Icos Corporation Modulation of ligand binding/enzymatic activity of alpha beta proteins
WO2002072030A2 (en) * 2001-03-13 2002-09-19 The General Hospital Corporation High affinity integrin polypeptides and uses thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HUTH J R ET AL: "NMR AND MUTAGENESIS EVIDENCE FOR AND I DOMAIN ALLOSTERIC SITE THAT REGULATES LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN 1 LIGAND BINDING", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 97, no. 10, 9 May 2000 (2000-05-09), pages 5231 - 5236, XP000938664, ISSN: 0027-8424 *
LI RUI ET AL: "Two functional states of the CD11b A-domain: Correlations with key features of two Mn2+-complexed crystal structures", THE JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, US, vol. 143, no. 6, 14 December 1998 (1998-12-14), pages 1523 - 1534, XP002209418, ISSN: 0021-9525 *
OXVIG CLAUS LU C ET AL: "Conformational changes in tertiary structure near the ligand binding site of an integrin I domain", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 96, no. 5, 2 March 1999 (1999-03-02), pages 2215 - 2220, XP002209413, ISSN: 0027-8424 *
See also references of WO0209737A1 *

Also Published As

Publication number Publication date
MXPA03000981A (es) 2003-09-05
AU2001286403A1 (en) 2002-02-13
CA2418120A1 (en) 2002-02-07
JP2004504827A (ja) 2004-02-19
EP1311282A1 (de) 2003-05-21

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20030228

AK Designated contracting states

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 07K 14/705 B

Ipc: 7C 12N 15/00 A

A4 Supplementary search report drawn up and despatched

Effective date: 20050527

17Q First examination report despatched

Effective date: 20060721

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080201