EP1299327A4 - Phosphorylated polypeptides and uses related thereto - Google Patents

Phosphorylated polypeptides and uses related thereto

Info

Publication number
EP1299327A4
EP1299327A4 EP01939871A EP01939871A EP1299327A4 EP 1299327 A4 EP1299327 A4 EP 1299327A4 EP 01939871 A EP01939871 A EP 01939871A EP 01939871 A EP01939871 A EP 01939871A EP 1299327 A4 EP1299327 A4 EP 1299327A4
Authority
EP
European Patent Office
Prior art keywords
uses related
phosphorylated polypeptides
phosphorylated
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01939871A
Other languages
German (de)
French (fr)
Other versions
EP1299327A2 (en
Inventor
Sidney Pestka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pestka Biomedical Laboratories Inc
Original Assignee
Pestka Biomedical Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pestka Biomedical Laboratories Inc filed Critical Pestka Biomedical Laboratories Inc
Publication of EP1299327A2 publication Critical patent/EP1299327A2/en
Publication of EP1299327A4 publication Critical patent/EP1299327A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP01939871A 2000-05-31 2001-05-31 Phosphorylated polypeptides and uses related thereto Withdrawn EP1299327A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US20824000P 2000-05-31 2000-05-31
US208240P 2000-05-31
US25529900P 2000-12-13 2000-12-13
US255299P 2000-12-13
PCT/US2001/017935 WO2001092469A2 (en) 2000-05-31 2001-05-31 Phosphorylated polypeptides and uses related thereto

Publications (2)

Publication Number Publication Date
EP1299327A2 EP1299327A2 (en) 2003-04-09
EP1299327A4 true EP1299327A4 (en) 2005-03-02

Family

ID=26903029

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01939871A Withdrawn EP1299327A4 (en) 2000-05-31 2001-05-31 Phosphorylated polypeptides and uses related thereto

Country Status (5)

Country Link
EP (1) EP1299327A4 (en)
JP (1) JP2003534790A (en)
AU (2) AU2001265343B2 (en)
CA (1) CA2410754A1 (en)
WO (1) WO2001092469A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050064507A1 (en) * 2003-09-11 2005-03-24 James Stephen Shaw Determining kinase specificity
JP5344391B2 (en) * 2009-02-23 2013-11-20 国立大学法人北陸先端科学技術大学院大学 Molecular model of protein molecule and method for producing the same
CN105188728B (en) 2013-05-07 2021-11-09 默克专利股份有限公司 Peptides and peptide-active substance conjugates for renal targeting

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0372707A2 (en) * 1988-10-28 1990-06-13 Pestka Biomedical Laboratories, Inc. Modified proteins, modified interferons, alphas and beta, phosphorylated proteins and analogues, DNA sequences, applications and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923802A (en) * 1985-06-13 1990-05-08 Immunex Corporation Peptide substrates for the detection, characterization and purification of protein kinase C
US5986061A (en) * 1988-10-28 1999-11-16 Pbl Biomedical Laboratories Phosphorylated fusion proteins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0372707A2 (en) * 1988-10-28 1990-06-13 Pestka Biomedical Laboratories, Inc. Modified proteins, modified interferons, alphas and beta, phosphorylated proteins and analogues, DNA sequences, applications and uses thereof

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
FRYXELL D ET AL: "Genetic construction of a phosphorylation site in ricin A chain: Specific radiolabeling of recombinant proteins for localization and degradation studies", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 210, no. 2, 1995, pages 253 - 259, XP002310942, ISSN: 0006-291X *
KEMP B E ET AL: "ROLE OF MULTIPLE BASIC RESIDUES IN DETERMINING THE SUBSTRATE SPECIFICITY OF CYCLIC AMP DEPENDENT PROTEIN KINASE", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 252, no. 14, 1977, pages 4888 - 4894, XP002310943, ISSN: 0021-9258 *
LIN L ET AL: "Construction of Phosphorylatable Chimeric Monoclonal Antibody CC49 with a Casein Kinase I Recognition Site", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, US, vol. 15, no. 1, February 1999 (1999-02-01), pages 83 - 91, XP004441745, ISSN: 1046-5928 *
LIN L ET AL: "CONSTRUCTION OF PHOSPHORYLATABLE CHIMERIC MONOCLONAL ANTIBODY CC49", INTERNATIONAL JOURNAL OF ONCOLOGY, EDITORIAL ACADEMY OF THE INTERNATIONAL JOURNAL OF ONCOLOGY,, GR, vol. 13, no. 1, July 1998 (1998-07-01), pages 115 - 120, XP009023663, ISSN: 1019-6439 *
LIN L ET AL: "CONSTRUCTION OF PHOSPHORYLATABLE MONOCLONAL ANTIBODY CC49 WITH A CASEIN KINASE II RECOGNITION SITE", ANTICANCER RESEARCH, HELENIC ANTICANCER INSTITUTE, ATHENS,, GR, vol. 18, no. 6A, November 1998 (1998-11-01), pages 3971 - 3978, XP009023665, ISSN: 0250-7005 *
LIN L ET AL: "CONSTRUCTION OF PHOSPHORYLATABLE MONOCLONAL ANTIBODY TO A TUMOR-ASSOCIATED ANTIGEN", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 56, no. 18, 15 September 1996 (1996-09-15), pages 4250 - 4254, XP001156392, ISSN: 0008-5472 *
MOHANRAJ D ET AL: "Expression and radiolabeling of recombinant proteins containing a phosphorylation motif", PROTEIN EXPRESSION AND PURIFICATION, vol. 8, no. 2, 1996, pages 175 - 182, XP002310941, ISSN: 1046-5928 *
PESTKA S ET AL: "Introduction of Protein Kinase Recognition Sites into Proteins: A Review of Their Preparation, Advantages, and Applications", PROTEIN EXPRESSION AND PURIFICATION, ACADEMIC PRESS, SAN DIEGO, CA, US, vol. 17, no. 2, November 1999 (1999-11-01), pages 203 - 214, XP004441603, ISSN: 1046-5928 *
PESTKA S ET AL: "Use of phosphorylation site tags in proteins", METHODS IN ENZYMOLOGY 2000 UNITED STATES, vol. 327, 17 October 2000 (2000-10-17), pages 594 - 613, XP001157109, ISSN: 0076-6879 *
WU J ET AL: "IDENTIFYING SUBSTRATE MOTIFS OF PROTEIN KINASES BY A RANDOM LIBRARY APPROACH", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, PA, US, vol. 33, 1994, pages 14825 - 14833, XP000952722, ISSN: 0006-2960 *

Also Published As

Publication number Publication date
CA2410754A1 (en) 2001-12-06
AU2001265343B2 (en) 2006-08-03
EP1299327A2 (en) 2003-04-09
JP2003534790A (en) 2003-11-25
WO2001092469A2 (en) 2001-12-06
AU6534301A (en) 2001-12-11
WO2001092469A3 (en) 2002-05-16

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Legal Events

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Owner name: PBL BIOMEDICAL LABORATORIES

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: PESTKA BIOMEDICAL LABORATORIES, INC.

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 12N 15/10 B

Ipc: 7C 07K 1/13 B

Ipc: 7G 01N 33/534 B

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