EP1259236A4 - Inhibiteurs de tyrosine-kinase - Google Patents
Inhibiteurs de tyrosine-kinaseInfo
- Publication number
- EP1259236A4 EP1259236A4 EP01914424A EP01914424A EP1259236A4 EP 1259236 A4 EP1259236 A4 EP 1259236A4 EP 01914424 A EP01914424 A EP 01914424A EP 01914424 A EP01914424 A EP 01914424A EP 1259236 A4 EP1259236 A4 EP 1259236A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- tyrosine kinase
- kinase inhibitors
- inhibitors
- tyrosine
- kinase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18502400P | 2000-02-25 | 2000-02-25 | |
US185024P | 2000-02-25 | ||
PCT/US2001/005567 WO2001062252A1 (fr) | 2000-02-25 | 2001-02-21 | Inhibiteurs de tyrosine-kinase |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1259236A1 EP1259236A1 (fr) | 2002-11-27 |
EP1259236A4 true EP1259236A4 (fr) | 2004-11-03 |
Family
ID=22679242
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01914424A Withdrawn EP1259236A4 (fr) | 2000-02-25 | 2001-02-21 | Inhibiteurs de tyrosine-kinase |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1259236A4 (fr) |
JP (1) | JP2003523390A (fr) |
AU (1) | AU778417B2 (fr) |
CA (1) | CA2400923A1 (fr) |
WO (1) | WO2001062252A1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL150388A0 (en) | 1999-12-24 | 2002-12-01 | Aventis Pharma Ltd | Azaindoles |
AU2001293233A1 (en) | 2000-09-01 | 2002-03-13 | Chiron Corporation | Aza heterocyclic derivatives and their therapeutic use |
EP1650203B1 (fr) | 2000-09-11 | 2008-02-20 | Novartis Vaccines and Diagnostics, Inc. | Procédé de pröparation des dérivés quinéolinone benzimidazol-2-yliques. |
GB0115109D0 (en) | 2001-06-21 | 2001-08-15 | Aventis Pharma Ltd | Chemical compounds |
JP2005506366A (ja) * | 2001-10-25 | 2005-03-03 | ノバルティス アクチエンゲゼルシャフト | 選択的シクロオキシゲナーゼ−2阻害剤を含む組合せ剤 |
US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
US6797825B2 (en) | 2001-12-13 | 2004-09-28 | Abbott Laboratories | Protein kinase inhibitors |
US6822097B1 (en) | 2002-02-07 | 2004-11-23 | Amgen, Inc. | Compounds and methods of uses |
AU2003288899B2 (en) | 2002-08-23 | 2009-09-03 | Novartis Vaccines And Diagnostics, Inc. | Benzimidazole quinolinones and uses thereof |
US20060228331A1 (en) | 2003-10-10 | 2006-10-12 | Novo Nordisk A/S | IL-21 Derivatives and variants |
MXPA06004199A (es) * | 2003-10-17 | 2006-06-28 | Novo Nordisk As | Terapia en combinacion. |
JP4890255B2 (ja) | 2003-11-07 | 2012-03-07 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 改良された薬物特性を有するキノリノン化合物の薬学的に受容可能な塩 |
WO2006071035A1 (fr) * | 2004-12-31 | 2006-07-06 | Lg Life Sciences, Ltd. | Nouveaux derives de ([1,3]thiazolo[5,4-b]pyridin-2-yl)-2-carboxamide |
PL2301546T3 (pl) | 2005-01-27 | 2015-03-31 | Novartis Ag | Leczenie guzów z przerzutami |
JP5545925B2 (ja) | 2005-05-17 | 2014-07-09 | ノバルティス アーゲー | ヘテロ環化合物の合成方法 |
GB0614471D0 (en) | 2006-07-20 | 2006-08-30 | Syngenta Ltd | Herbicidal Compounds |
JP2011513488A (ja) * | 2008-03-10 | 2011-04-28 | サノフィ−アベンティス | 眼関連障害の治療 |
AU2014205483B2 (en) | 2013-01-10 | 2017-11-30 | Gilead Sciences, Inc. | Non-selective kinase inhibitors |
CN111743901B (zh) | 2013-10-11 | 2023-09-12 | 普尔莫凯恩股份有限公司 | 喷雾干燥制剂 |
KR102543227B1 (ko) | 2016-10-27 | 2023-06-13 | 풀모킨 인코포레이티드 | 폐고혈압을 치료하기 위한 병용 요법 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001062251A1 (fr) * | 2000-02-25 | 2001-08-30 | Merck & Co., Inc. | Inhibiteurs de tyrosine kinase |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG64322A1 (en) * | 1991-05-10 | 1999-04-27 | Rhone Poulenc Rorer Int | Bis mono and bicyclic aryl and heteroaryl compounds which inhibit egf and/or pdgf receptor tyrosine kinase |
US6162804A (en) * | 1997-09-26 | 2000-12-19 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
-
2001
- 2001-02-21 EP EP01914424A patent/EP1259236A4/fr not_active Withdrawn
- 2001-02-21 WO PCT/US2001/005567 patent/WO2001062252A1/fr active IP Right Grant
- 2001-02-21 AU AU39814/01A patent/AU778417B2/en not_active Ceased
- 2001-02-21 CA CA002400923A patent/CA2400923A1/fr not_active Abandoned
- 2001-02-21 JP JP2001561318A patent/JP2003523390A/ja not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001062251A1 (fr) * | 2000-02-25 | 2001-08-30 | Merck & Co., Inc. | Inhibiteurs de tyrosine kinase |
Non-Patent Citations (2)
Title |
---|
No further relevant documents disclosed * |
See also references of WO0162252A1 * |
Also Published As
Publication number | Publication date |
---|---|
WO2001062252A1 (fr) | 2001-08-30 |
JP2003523390A (ja) | 2003-08-05 |
CA2400923A1 (fr) | 2001-08-30 |
AU3981401A (en) | 2001-09-03 |
AU778417B2 (en) | 2004-12-02 |
EP1259236A1 (fr) | 2002-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020925 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Free format text: AL PAYMENT 20020925;LT PAYMENT 20020925;LV PAYMENT 20020925;MK PAYMENT 20020925;RO PAYMENT 20020925;SI PAYMENT 20020925 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20040921 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7C 07D 519/00 B Ipc: 7A 61K 31/4355 A Ipc: 7C 07D 209:00 J Ipc: 7A 61K 31/437 B Ipc: 7A 61P 35/00 B Ipc: 7A 61K 31/4375 B Ipc: 7C 07D 471/04 B Ipc: 7A 61K 31/4365 B Ipc: 7C 07D 471/04 J Ipc: 7C 07D 221:00 J |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: HUNGATE, RANDALL, W. Inventor name: HARTMAN, GEORGE, D. Inventor name: FRALEY, MARK, E. |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/4355 20060101AFI20070227BHEP Ipc: C07D 221/00 20060101ALN20070227BHEP Ipc: A61P 35/00 20060101ALI20070227BHEP Ipc: A61K 31/4365 20060101ALI20070227BHEP Ipc: A61K 31/437 20060101ALI20070227BHEP Ipc: C07D 471/04 20060101ALI20070227BHEP Ipc: C07D 519/00 20060101ALI20070227BHEP Ipc: A61K 31/4375 20060101ALI20070227BHEP Ipc: C07D 209/00 20060101ALN20070227BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20070724 |