EP1224265A4 - Novel human potassium channel subunit - Google Patents
Novel human potassium channel subunitInfo
- Publication number
- EP1224265A4 EP1224265A4 EP00968933A EP00968933A EP1224265A4 EP 1224265 A4 EP1224265 A4 EP 1224265A4 EP 00968933 A EP00968933 A EP 00968933A EP 00968933 A EP00968933 A EP 00968933A EP 1224265 A4 EP1224265 A4 EP 1224265A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- potassium channel
- novel human
- channel subunit
- human potassium
- subunit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15878199P | 1999-10-12 | 1999-10-12 | |
US158781P | 1999-10-12 | ||
PCT/US2000/028014 WO2001027246A1 (en) | 1999-10-12 | 2000-10-10 | Novel human potassium channel subunit |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1224265A1 EP1224265A1 (en) | 2002-07-24 |
EP1224265A4 true EP1224265A4 (en) | 2004-11-24 |
Family
ID=22569684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00968933A Withdrawn EP1224265A4 (en) | 1999-10-12 | 2000-10-10 | Novel human potassium channel subunit |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1224265A4 (en) |
JP (1) | JP2003511065A (en) |
CA (1) | CA2387237A1 (en) |
WO (1) | WO2001027246A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE452988T1 (en) * | 1999-04-15 | 2010-01-15 | Univ Utah Res Found | MINK-ASSOCIATED GENES, FORMATION OF POTASSIUM CHANNELS AND ASSOCIATION TO CARDIAC ARRHYTMIA |
US6864364B1 (en) | 1999-04-15 | 2005-03-08 | University Of Utah Research Foundation | MinK-related genes, formation of potassium channels and association with cardiac arrhythmia |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000063434A1 (en) * | 1999-04-15 | 2000-10-26 | University Of Utah Research Foundation | MinK-RELATED GENES, FORMATION OF POTASSIUM CHANNELS AND ASSOCIATION WITH CARDIAC ARRHYTHMIA |
WO2002022875A2 (en) * | 2000-09-11 | 2002-03-21 | Yale University | Polymorphisms associated with cardiac arrythmia |
-
2000
- 2000-10-10 WO PCT/US2000/028014 patent/WO2001027246A1/en not_active Application Discontinuation
- 2000-10-10 EP EP00968933A patent/EP1224265A4/en not_active Withdrawn
- 2000-10-10 JP JP2001530451A patent/JP2003511065A/en not_active Withdrawn
- 2000-10-10 CA CA002387237A patent/CA2387237A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000063434A1 (en) * | 1999-04-15 | 2000-10-26 | University Of Utah Research Foundation | MinK-RELATED GENES, FORMATION OF POTASSIUM CHANNELS AND ASSOCIATION WITH CARDIAC ARRHYTHMIA |
WO2002022875A2 (en) * | 2000-09-11 | 2002-03-21 | Yale University | Polymorphisms associated with cardiac arrythmia |
Non-Patent Citations (11)
Title |
---|
ABBOTT GEOFFREY W ET AL: "Disease-associated mutations in KCNE potassium channel subunits (MiRPs) reveal promiscuous disruption of multiple currents and conservation of mechanism", FASEB JOURNAL, vol. 16, no. 3, March 2002 (2002-03-01), pages 390 - 400, XP002297389, ISSN: 0892-6638 * |
DATABASE GENEBANK 13 May 1998 (1998-05-13), "Homo sapiens genomic DNA, chromosome 21q22.1, segment 23/28, complete sequence", XP002297394, retrieved from GENEBANK Database accession no. AP000052 * |
DATABASE GENEBANK 29 April 1999 (1999-04-29), ABBOTT, G.W. ET AL.: "Rattus norvegicus minK-related peptide 1 mRNA, complete cds", XP002297393, retrieved from GENEBANK Database accession no. AF071003 * |
DATABASE GENEBANK 29 April 1999 (1999-04-29), ABBOTT, G.W.ET AL.: "Homo sapiens minK-related peptide 1 mRNA, complete cds", XP002297392, retrieved from GENEBANK Database accession no. AF071002 * |
DATABASE UNIPROT 30 May 2000 (2000-05-30), "Potassium voltage-gated channel subfamily E member 2 (Minimum potassium ion channel-related peptide 1) (Potassium channel beta subunit MiRP1) (MinK-related peptide 1)", XP002297395, retrieved from UNIPROT Database accession no. Q9Y6J6 * |
DATABASE UNIPROT 30 May 2000 (2000-05-30), "Potassium voltage-gated channel subfamily E member 2 (Minimum potassium ion channel-related peptide 1) (Potassium channel beta subunit MiRP1) (MinK-related peptide 1)", XP002297396, retrieved from UNIPROT Database accession no. Q9WTW0 * |
ISBRANDT DIRK ET AL: "Identification and functional characterization of a novel KCNE2 (MiRP1) mutation that alters HERG channel kinetics", JOURNAL OF MOLECULAR MEDICINE (BERLIN), vol. 80, no. 8, August 2002 (2002-08-01), pages 524 - 532, XP002297390, ISSN: 0946-2716 * |
See also references of WO0127246A1 * |
TINEL N ET AL: "M-type KCNQ2-KCNQ3 potassium channels are modulated by the KCNE2 subunit", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 480, no. 2-3, 1 September 2000 (2000-09-01), pages 137 - 141, XP004337508, ISSN: 0014-5793 * |
TINEL NORBERT ET AL: "KCNE2 confers background current characteristics to the cardiac KCNQ1 potassium channel", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, vol. 19, no. 23, 1 December 2000 (2000-12-01), pages 6326 - 6330, XP002297388, ISSN: 0261-4189 * |
YU H ET AL: "MinK-related peptide 1: A beta subunit for the HCN ion channel subunit family enhances expression and speeds activation.", CIRCULATION RESEARCH. 22 JUN 2001, vol. 88, no. 12, 22 June 2001 (2001-06-22), pages E84 - E87, XP002297391, ISSN: 1524-4571 * |
Also Published As
Publication number | Publication date |
---|---|
JP2003511065A (en) | 2003-03-25 |
EP1224265A1 (en) | 2002-07-24 |
WO2001027246A1 (en) | 2001-04-19 |
CA2387237A1 (en) | 2001-04-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020513 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20041008 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20060919 |