EP1221961A4 - Induction d'une forte reponse immunitaire a un auto-antigene associe aux tumeurs - Google Patents
Induction d'une forte reponse immunitaire a un auto-antigene associe aux tumeursInfo
- Publication number
- EP1221961A4 EP1221961A4 EP00970926A EP00970926A EP1221961A4 EP 1221961 A4 EP1221961 A4 EP 1221961A4 EP 00970926 A EP00970926 A EP 00970926A EP 00970926 A EP00970926 A EP 00970926A EP 1221961 A4 EP1221961 A4 EP 1221961A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- induction
- self
- immune response
- associated antigen
- tumor associated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 230000028993 immune response Effects 0.000 title 1
- 230000006698 induction Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00119—Melanoma antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
- C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
- C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15915399P | 1999-10-13 | 1999-10-13 | |
US159153P | 1999-10-13 | ||
PCT/US2000/028517 WO2001026672A1 (fr) | 1999-10-13 | 2000-10-13 | Induction d'une forte reponse immunitaire a un auto-antigene associe aux tumeurs |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1221961A1 EP1221961A1 (fr) | 2002-07-17 |
EP1221961A4 true EP1221961A4 (fr) | 2004-03-31 |
Family
ID=22571310
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00970926A Withdrawn EP1221961A4 (fr) | 1999-10-13 | 2000-10-13 | Induction d'une forte reponse immunitaire a un auto-antigene associe aux tumeurs |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1221961A4 (fr) |
JP (1) | JP2003514774A (fr) |
AU (1) | AU8024100A (fr) |
CA (1) | CA2385186A1 (fr) |
WO (1) | WO2001026672A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1287831B1 (fr) * | 2001-09-03 | 2006-11-22 | Bio Life Science Forschungs- und Entwicklungsges.m.b.H. | Mimotopes d'antigènes et vaccin contre des maladies cancéreuses |
AU2004312411B8 (en) | 2003-12-31 | 2011-11-24 | Schering-Plough Pty. Limited | Neutralizing epitope-based growth enhancing vaccine |
CA2594276A1 (fr) | 2004-12-30 | 2006-07-13 | Schering-Plough Ltd. | Vaccins favorisant la croissance a base d'epitopes neutralisants |
WO2011009090A1 (fr) | 2009-07-16 | 2011-01-20 | Xoma Technology Ltd. | Anticorps dirigés contre lantigène de poids moléculaire élevé associé au mélanome |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0759442A1 (fr) * | 1987-09-10 | 1997-02-26 | Oncogen Limited Partnership | Immunothérapie pour les tumeurs par utilisation d'anticorps anti-idiotypiques |
WO1997023237A1 (fr) * | 1995-12-22 | 1997-07-03 | Immunomedics, Inc. | Utilisation d'immunoconjugues pour accroitre l'efficacite des vaccins multietapes stimulant les reactions immunitaires en cascade |
US5780029A (en) * | 1989-11-14 | 1998-07-14 | New York Medical College | Antidiotypic monoclonal antibodies for treatment of melanoma |
WO2000038515A1 (fr) * | 1998-12-24 | 2000-07-06 | New York Medical College | Mimetiques peptidiques utiles pour traiter des maladies |
-
2000
- 2000-10-13 JP JP2001529734A patent/JP2003514774A/ja active Pending
- 2000-10-13 EP EP00970926A patent/EP1221961A4/fr not_active Withdrawn
- 2000-10-13 CA CA002385186A patent/CA2385186A1/fr not_active Abandoned
- 2000-10-13 WO PCT/US2000/028517 patent/WO2001026672A1/fr active Application Filing
- 2000-10-13 AU AU80241/00A patent/AU8024100A/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0759442A1 (fr) * | 1987-09-10 | 1997-02-26 | Oncogen Limited Partnership | Immunothérapie pour les tumeurs par utilisation d'anticorps anti-idiotypiques |
US5780029A (en) * | 1989-11-14 | 1998-07-14 | New York Medical College | Antidiotypic monoclonal antibodies for treatment of melanoma |
WO1997023237A1 (fr) * | 1995-12-22 | 1997-07-03 | Immunomedics, Inc. | Utilisation d'immunoconjugues pour accroitre l'efficacite des vaccins multietapes stimulant les reactions immunitaires en cascade |
WO2000038515A1 (fr) * | 1998-12-24 | 2000-07-06 | New York Medical College | Mimetiques peptidiques utiles pour traiter des maladies |
Non-Patent Citations (7)
Title |
---|
DURRANT L G ET AL: "Development of second generation monoclonal antibodies recognising Lewis-y!b antigen by anti-idiotypic immunisation", HYBRIDOMA, vol. 12, no. 6, 1993, pages 647 - 660, XP008005496, ISSN: 0272-457X * |
DYALL R ET AL: "HETEROCLITIC IMMUNIZATION INDUCES TUMOR IMMUNITY", JOURNAL OF EXPERIMENTAL MEDICINE, TOKYO, JP, vol. 188, no. 9, 2 November 1998 (1998-11-02), pages 1553 - 1561, XP002947142, ISSN: 0022-1007 * |
FERRONE SOLDANO: "Active specific immunotherapy of human melanoma with mouse anti-idiotypic (anti-id) monoclonal antibodies (MAB)", MEDICAL INTELLIGENCE UNIT;IMMUNOTHERAPY OF MALIGNANT MELANOMA, 1996, Chapman and Hall, Inc., 29 West 35th Street, New York, New York, USA; Chapman and Hall Ltd., 2-6 Boundary Row, London SE1 8HN, England, pages 73 - 95, XP009024959, ISBN: 0-412-10491-1 * |
PARKHURST M R ET AL: "Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD.: 1950) UNITED STATES 15 SEP 1996, vol. 157, no. 6, 15 September 1996 (1996-09-15), pages 2539 - 2548, XP002096010, ISSN: 0022-1767 * |
ROSENBERG S A ET AL: "Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma", NATURE MEDICINE, NATURE PUBLISHING, CO, US, vol. 4, no. 3, 1 March 1998 (1998-03-01), pages 321 - 327, XP002091661, ISSN: 1078-8956 * |
See also references of WO0126672A1 * |
WANG X ET AL: "IMMUNOTHERAPY OF MELANOMA: PEPTIDE MIMICS OF A HUMAN HIGH MOLECULARWEIGHT-MELANOMA ASSOCIATED ANTIGEN", MEDICINA, BUENOS AIRES, AR, vol. 60, no. SUPPL 2, August 2000 (2000-08-01), pages 48 - 50, XP001053496, ISSN: 0025-7680 * |
Also Published As
Publication number | Publication date |
---|---|
JP2003514774A (ja) | 2003-04-22 |
WO2001026672A9 (fr) | 2002-08-01 |
EP1221961A1 (fr) | 2002-07-17 |
WO2001026672A1 (fr) | 2001-04-19 |
AU8024100A (en) | 2001-04-23 |
CA2385186A1 (fr) | 2001-04-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020422 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20040213 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7A 61K 31/70 B Ipc: 7A 61K 39/40 B Ipc: 7A 61K 39/00 B Ipc: 7C 07K 16/42 B Ipc: 7A 61K 39/44 B Ipc: 7A 01N 43/04 B Ipc: 7A 61K 39/42 B Ipc: 7A 61K 38/00 A Ipc: 7A 61K 39/395 B Ipc: 7C 07K 7/08 B |
|
17Q | First examination report despatched |
Effective date: 20051019 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20080501 |