EP1214445A4 - Compositions pour la detection de l'activite enzymatique dans des echantillons biologiques et leurs procedes d'utilisations - Google Patents
Compositions pour la detection de l'activite enzymatique dans des echantillons biologiques et leurs procedes d'utilisationsInfo
- Publication number
- EP1214445A4 EP1214445A4 EP00961782A EP00961782A EP1214445A4 EP 1214445 A4 EP1214445 A4 EP 1214445A4 EP 00961782 A EP00961782 A EP 00961782A EP 00961782 A EP00961782 A EP 00961782A EP 1214445 A4 EP1214445 A4 EP 1214445A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- detection
- methods
- enzyme activity
- biological samples
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/394,019 US6936687B1 (en) | 1997-02-20 | 1999-09-10 | Compositions for the detection of enzyme activity in biological samples and methods of use thereof |
US394019 | 1999-09-10 | ||
PCT/US2000/024882 WO2001018238A1 (fr) | 1999-09-10 | 2000-09-11 | Compositions pour la detection de l'activite enzymatique dans des echantillons biologiques et leurs procedes d'utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1214445A1 EP1214445A1 (fr) | 2002-06-19 |
EP1214445A4 true EP1214445A4 (fr) | 2007-01-24 |
Family
ID=23557207
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00961782A Withdrawn EP1214445A4 (fr) | 1999-09-10 | 2000-09-11 | Compositions pour la detection de l'activite enzymatique dans des echantillons biologiques et leurs procedes d'utilisations |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1214445A4 (fr) |
JP (1) | JP2003508080A (fr) |
AU (1) | AU7368800A (fr) |
CA (1) | CA2384021A1 (fr) |
WO (1) | WO2001018238A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6893868B2 (en) | 1997-02-20 | 2005-05-17 | Onco Immunin, Inc. | Homo-doubly labeled compositions for the detection of enzyme activity in biological samples |
US7312302B2 (en) | 1997-02-20 | 2007-12-25 | Oncolmmunin, Inc. | Compositions for the detection of enzyme activity in biological samples and methods of use thereof |
US6037137A (en) | 1997-02-20 | 2000-03-14 | Oncoimmunin, Inc. | Fluorogenic peptides for the detection of protease activity |
AU2002336421A1 (en) * | 2001-08-31 | 2003-04-14 | The Government Of The United States Of America, Asrepresented By The Secretary Of The Department Of | Measurements of multiple molecules using a cryoarray |
GB0200479D0 (en) * | 2002-01-09 | 2002-02-27 | Medical Res Council | Fluorogenic protease substrates |
US7927871B2 (en) | 2002-01-29 | 2011-04-19 | Oncoimmunin, Inc. | Visualization and quantitation of cellular cytotoxicity using cell-permeable fluorogenic protease substrates and caspase activity indicator markers |
GB0311948D0 (en) * | 2003-05-23 | 2003-06-25 | Stockport Innovation Ltd | Light emitting probes |
JP5397229B2 (ja) * | 2008-02-22 | 2014-01-22 | 和光純薬工業株式会社 | β−グルカン及び/又はエンドトキシン測定用基質並びに測定方法 |
JP2015502365A (ja) * | 2011-12-12 | 2015-01-22 | オンコイミューニン,インコーポレイティド | オリゴヌクレオチドのイン−ビボ送達 |
WO2023032995A1 (fr) | 2021-08-31 | 2023-03-09 | 富士フイルム株式会社 | Composé et biomatériau marqué l'utilisant |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998037226A1 (fr) * | 1997-02-20 | 1998-08-27 | Oncoimmunin, Inc. | Compositions de detection de l'activite enzymatique dans des echantillons biologiques et procedes d'utilisation de telles compositions |
WO2000004914A1 (fr) * | 1998-07-21 | 2000-02-03 | Cytovia, Inc. | Nouveaux colorants fluorescents et leurs applications dans des methodes de criblage par fluorescence de cellules entieres pour des caspases, peptidases, proteases et autres enzymes ainsi que procedes de leur utilisation |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5723288A (en) * | 1994-05-06 | 1998-03-03 | The University Of North Carolina At Chapel Hill | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor |
US5804395A (en) * | 1995-12-01 | 1998-09-08 | The United States Of America As Represented By The Secretary Of The Navy | Fluorescence polarization assays of enzymes and substrates therefore |
-
2000
- 2000-09-11 CA CA002384021A patent/CA2384021A1/fr not_active Abandoned
- 2000-09-11 JP JP2001521773A patent/JP2003508080A/ja active Pending
- 2000-09-11 AU AU73688/00A patent/AU7368800A/en not_active Abandoned
- 2000-09-11 EP EP00961782A patent/EP1214445A4/fr not_active Withdrawn
- 2000-09-11 WO PCT/US2000/024882 patent/WO2001018238A1/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998037226A1 (fr) * | 1997-02-20 | 1998-08-27 | Oncoimmunin, Inc. | Compositions de detection de l'activite enzymatique dans des echantillons biologiques et procedes d'utilisation de telles compositions |
WO2000004914A1 (fr) * | 1998-07-21 | 2000-02-03 | Cytovia, Inc. | Nouveaux colorants fluorescents et leurs applications dans des methodes de criblage par fluorescence de cellules entieres pour des caspases, peptidases, proteases et autres enzymes ainsi que procedes de leur utilisation |
Non-Patent Citations (4)
Title |
---|
MATAYOSHI E D ET AL: "NOVEL FLUOROGENIC SUBSTRATES FOR ASSAYING RETROVIRAL PROTEASES BY RESONANCE ENERGY TRANSFER", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 24, 23 February 1990 (1990-02-23), pages 954 - 958, XP002056345, ISSN: 0036-8075 * |
See also references of WO0118238A1 * |
TOTH M V ET AL: "A SIMPLE CONTINUOUS FLUOROMETRIC ASSAY FOR HIV PROTEASE", INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, MUNKSGAARD, COPENHAGEN, DK, vol. 36, no. 6, 1990, pages 544 - 550, XP001160870, ISSN: 0367-8377 * |
WANG G T ET AL: "A continuous fluorescence assay of renin activity.", ANALYTICAL BIOCHEMISTRY. 1 MAY 1993, vol. 210, no. 2, 1 May 1993 (1993-05-01), pages 351 - 359, XP002406820, ISSN: 0003-2697 * |
Also Published As
Publication number | Publication date |
---|---|
AU7368800A (en) | 2001-04-10 |
EP1214445A1 (fr) | 2002-06-19 |
JP2003508080A (ja) | 2003-03-04 |
WO2001018238A1 (fr) | 2001-03-15 |
CA2384021A1 (fr) | 2001-03-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020410 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20061228 |
|
17Q | First examination report despatched |
Effective date: 20080226 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20080909 |