EP1214079A4 - MEDICINES FOR TREATING FRACTURES - Google Patents

MEDICINES FOR TREATING FRACTURES

Info

Publication number
EP1214079A4
EP1214079A4 EP00952791A EP00952791A EP1214079A4 EP 1214079 A4 EP1214079 A4 EP 1214079A4 EP 00952791 A EP00952791 A EP 00952791A EP 00952791 A EP00952791 A EP 00952791A EP 1214079 A4 EP1214079 A4 EP 1214079A4
Authority
EP
European Patent Office
Prior art keywords
drug
treating fractures
fractures
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00952791A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1214079A1 (en
Inventor
David G Little
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Royal Alexandra Hospital for Children
Original Assignee
Royal Alexandra Hospital for Children
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Royal Alexandra Hospital for Children filed Critical Royal Alexandra Hospital for Children
Publication of EP1214079A1 publication Critical patent/EP1214079A1/en
Publication of EP1214079A4 publication Critical patent/EP1214079A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP00952791A 1999-08-19 2000-08-17 MEDICINES FOR TREATING FRACTURES Withdrawn EP1214079A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPQ232599 1999-08-19
AUPQ2325A AUPQ232599A0 (en) 1999-08-19 1999-08-19 Drug for treating fractures
PCT/AU2000/000982 WO2001013922A1 (en) 1999-08-19 2000-08-17 Drug for treating fractures

Publications (2)

Publication Number Publication Date
EP1214079A1 EP1214079A1 (en) 2002-06-19
EP1214079A4 true EP1214079A4 (en) 2004-03-24

Family

ID=3816500

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00952791A Withdrawn EP1214079A4 (en) 1999-08-19 2000-08-17 MEDICINES FOR TREATING FRACTURES

Country Status (16)

Country Link
EP (1) EP1214079A4 (no)
JP (1) JP2003507426A (no)
KR (1) KR20020027562A (no)
CN (1) CN100345548C (no)
AU (1) AUPQ232599A0 (no)
BR (1) BR0013416A (no)
CA (1) CA2381302A1 (no)
HK (1) HK1048441B (no)
HU (1) HUP0202396A3 (no)
IL (1) IL148166A0 (no)
NO (1) NO20020784L (no)
NZ (1) NZ517538A (no)
PL (1) PL353485A1 (no)
SK (1) SK2382002A3 (no)
WO (1) WO2001013922A1 (no)
ZA (1) ZA200202160B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ527351A (en) 2001-02-06 2005-01-28 Royal Alexandra Hosp Children Use of bisphosphonate for the treatment of osteonecrosis and for the management of patients at risk of developing ostenonecrosis
WO2002080933A1 (en) * 2001-04-03 2002-10-17 The Royal Alexandra Hospital For Children A drug for use in bone grafting
AUPR553701A0 (en) * 2001-06-07 2001-07-12 Royal Alexandra Hospital For Children, The A device for the delivery of a drug to a fractured bone
EP1508343B1 (en) * 2003-08-21 2015-11-04 AddBIO AB Bisphosponate coated implant device and method therefor
RU2326695C2 (ru) * 2003-09-19 2008-06-20 Пфайзер Продактс Инк. Фармацевтические композиции и способы, включающие комбинации 2-алкилиденовых производных 9-нор-витамина d и бисфосфоната
ITMI20040218A1 (it) * 2004-02-10 2004-05-10 Abiogen Pharma Spa Uso di neridronato sodico per promuovere la neoformazione ossea
ITMI20040641A1 (it) * 2004-03-31 2004-06-30 Tb Technology S R L Composizioni bioadesive bifunzionali per implantologia orale
AR048742A1 (es) * 2004-12-22 2006-05-24 Gador Sa Sistema de aplicacion de medicamentos intra-oral
JP5426168B2 (ja) * 2005-10-27 2014-02-26 トーメン メディカル アーゲー 歯科インプラント及びその製造方法
US8882740B2 (en) 2009-12-23 2014-11-11 Stryker Trauma Gmbh Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530360A (en) * 1981-11-19 1985-07-23 Duarte Luiz R Method for healing bone fractures with ultrasound
EP0600834A1 (en) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing
WO1994014455A1 (en) * 1992-12-23 1994-07-07 Merck & Co., Inc. Bisphosphonate/estrogen therapy for treating and preventing bone loss
WO1995030421A1 (en) * 1994-05-04 1995-11-16 Ciba-Geigy Ag Use of certain methanebisphosphonic acid derivatives to prevent prosthesis loosening and prosthesis migration

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2112515C1 (ru) * 1991-12-17 1998-06-10 Проктер энд Гэмбл Фармасьютикалз, Инк. Способ лечения остеопороза
AU670337B2 (en) * 1992-11-30 1996-07-11 Novartis Ag Use of certain methanebisphosphonic acid derivatives in fracture healing
US5403829A (en) * 1993-03-24 1995-04-04 Leiras Oy Use of bisphosphonates in endo-osteal bone surgery
US5646134A (en) * 1994-04-21 1997-07-08 Merck & Co., Inc. Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices
US5616571A (en) * 1995-06-06 1997-04-01 Merck & Co., Inc. Bisphosphonates prevent bone loss associated with immunosuppressive therapy
AU703887B2 (en) * 1995-06-06 1999-04-01 Merck & Co., Inc. Bisphosphonate therapy for bone loss associated with rheumatoid arthritis
US5853759A (en) * 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
GB9613722D0 (en) * 1996-06-28 1996-08-28 Univ Liverpool Chemical compounds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4530360A (en) * 1981-11-19 1985-07-23 Duarte Luiz R Method for healing bone fractures with ultrasound
EP0600834A1 (en) * 1992-11-30 1994-06-08 Ciba-Geigy Ag Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing
WO1994014455A1 (en) * 1992-12-23 1994-07-07 Merck & Co., Inc. Bisphosphonate/estrogen therapy for treating and preventing bone loss
WO1995030421A1 (en) * 1994-05-04 1995-11-16 Ciba-Geigy Ag Use of certain methanebisphosphonic acid derivatives to prevent prosthesis loosening and prosthesis migration

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DENISSEN H ET AL: "CERAMIC HYDROXYAPATITE IMPLANTS FOR THE RELEASE OF BIPHOSPHONATE", BONE AND MINERAL, SHANNON, IE, vol. 25, no. 2, 1994, pages 123 - 134, XP001015353 *
ECK J. ET AL: "Diagnosis and Treatment of Common Metabolic Spinal Disorders in the Geriatric Population", SOUTHERN MEDICAL JOURNAL, vol. 91, no. 12, 1998, pages 1089 - 1097, XP002906300 *
SABOKBAR A. ET AL: "Bisphosphonates in bone cement inhibit PMMA particle induced bone resorption", ANNALS OF RHEUMATIC DISEASES, vol. 57, no. 10, 1998, pages 614 - 618, XP002953301, DOI: 10.1136/ard.57.10.614 *
See also references of WO0113922A1 *

Also Published As

Publication number Publication date
ZA200202160B (en) 2003-08-27
PL353485A1 (en) 2003-11-17
WO2001013922A1 (en) 2001-03-01
HK1048441B (zh) 2008-02-22
HUP0202396A3 (en) 2005-02-28
CN100345548C (zh) 2007-10-31
EP1214079A1 (en) 2002-06-19
KR20020027562A (ko) 2002-04-13
CN1370071A (zh) 2002-09-18
SK2382002A3 (en) 2002-09-10
NZ517538A (en) 2003-07-25
CA2381302A1 (en) 2001-03-01
AUPQ232599A0 (en) 1999-09-09
NO20020784D0 (no) 2002-02-18
IL148166A0 (en) 2002-09-12
HK1048441A1 (en) 2003-04-04
BR0013416A (pt) 2002-04-30
JP2003507426A (ja) 2003-02-25
HUP0202396A2 (hu) 2002-11-28
NO20020784L (no) 2002-02-18

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Legal Events

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Effective date: 20020314

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A4 Supplementary search report drawn up and despatched

Effective date: 20040205

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Ipc: 7A 61K 19/00 B

Ipc: 7A 61K 31/663 A

Ipc: 7A 61K 31/675 B

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Effective date: 20041008

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Effective date: 20080903