EP1212341A4 - Polynucleotides and polypeptides encoded thereby distantly homologous to heparanase - Google Patents
Polynucleotides and polypeptides encoded thereby distantly homologous to heparanaseInfo
- Publication number
- EP1212341A4 EP1212341A4 EP00937164A EP00937164A EP1212341A4 EP 1212341 A4 EP1212341 A4 EP 1212341A4 EP 00937164 A EP00937164 A EP 00937164A EP 00937164 A EP00937164 A EP 00937164A EP 1212341 A4 EP1212341 A4 EP 1212341A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- heparanase
- polynucleotides
- polypeptides encoded
- distantly homologous
- distantly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102100024025 Heparanase Human genes 0.000 title 1
- 108010037536 heparanase Proteins 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01166—Heparanase (3.2.1.166)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14080199P | 1999-06-25 | 1999-06-25 | |
US140801P | 1999-06-25 | ||
PCT/IL2000/000358 WO2001000643A2 (en) | 1999-06-25 | 2000-06-19 | Polynucleotides and polypeptides encoded thereby distantly homologous to heparanase |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1212341A1 EP1212341A1 (en) | 2002-06-12 |
EP1212341A4 true EP1212341A4 (en) | 2002-11-27 |
Family
ID=22492846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00937164A Withdrawn EP1212341A4 (en) | 1999-06-25 | 2000-06-19 | Polynucleotides and polypeptides encoded thereby distantly homologous to heparanase |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP1212341A4 (en) |
JP (1) | JP2003503070A (en) |
KR (1) | KR20020028906A (en) |
CN (1) | CN1370178A (en) |
AU (1) | AU777343B2 (en) |
CA (1) | CA2377498A1 (en) |
HU (1) | HUP0300901A2 (en) |
IL (1) | IL146527A0 (en) |
MX (1) | MXPA01011708A (en) |
NO (1) | NO20015526L (en) |
PL (1) | PL362599A1 (en) |
WO (1) | WO2001000643A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000052178A1 (en) * | 1999-03-01 | 2000-09-08 | Insight Strategy & Marketing Ltd. | Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells |
EP1214423A1 (en) * | 1999-09-23 | 2002-06-19 | MERCK PATENT GmbH | Heparanase-2, a member of the heparanase protein family |
WO2001046392A2 (en) * | 1999-12-22 | 2001-06-28 | Oxford Glycosciences (Uk) Ltd. | Homologues of human heparanase and splice variants thereof |
JP2003518381A (en) * | 1999-12-23 | 2003-06-10 | シエーリング アクチエンゲゼルシャフト | Human heparanase-related polypeptides and nucleic acids |
GB0014447D0 (en) * | 2000-06-13 | 2000-08-09 | Smithkline Beecham Plc | Novel compounds |
WO2002004645A2 (en) * | 2000-07-12 | 2002-01-17 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | A second human heparanase, and splice variants thereof, with a predominant expression in skeletal muscle, heart and pancreas |
IL162276A0 (en) * | 2004-06-01 | 2005-11-20 | Hadasit Med Res Service | Nucleic acid molecules as heparanase potent inhibitors, compositions and methods of use thereof |
FI20085308A0 (en) * | 2008-04-11 | 2008-04-11 | Polysackaridforskning I Uppsal | Heparanase-free non-human mammals |
JP5622451B2 (en) * | 2010-06-21 | 2014-11-12 | 小川香料株式会社 | Tea extract |
JP6321506B2 (en) * | 2014-09-22 | 2018-05-09 | 株式会社 資生堂 | Whitening method with heparanase inhibitor and method for evaluating substances having whitening effect |
BR112018015164A2 (en) * | 2016-01-26 | 2018-12-26 | Nissan Chemical Corp | single stranded oligonucleotide |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999021975A1 (en) * | 1997-10-28 | 1999-05-06 | The Australian National University | Isolated nucleic acid molecule encoding mammalian endoglucuronidase and uses therefor |
WO1999057153A1 (en) * | 1998-05-01 | 1999-11-11 | Insight Strategy & Marketing Ltd. | Heparanase specific molecular probes and their use in research and medical applications |
-
2000
- 2000-06-19 CN CN00809505A patent/CN1370178A/en active Pending
- 2000-06-19 CA CA002377498A patent/CA2377498A1/en not_active Abandoned
- 2000-06-19 AU AU52448/00A patent/AU777343B2/en not_active Ceased
- 2000-06-19 IL IL14652700A patent/IL146527A0/en unknown
- 2000-06-19 JP JP2001507050A patent/JP2003503070A/en active Pending
- 2000-06-19 KR KR1020017016406A patent/KR20020028906A/en not_active Application Discontinuation
- 2000-06-19 MX MXPA01011708A patent/MXPA01011708A/en not_active Application Discontinuation
- 2000-06-19 WO PCT/IL2000/000358 patent/WO2001000643A2/en not_active Application Discontinuation
- 2000-06-19 PL PL00362599A patent/PL362599A1/en unknown
- 2000-06-19 EP EP00937164A patent/EP1212341A4/en not_active Withdrawn
- 2000-06-19 HU HU0300901A patent/HUP0300901A2/en unknown
-
2001
- 2001-11-12 NO NO20015526A patent/NO20015526L/en not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999021975A1 (en) * | 1997-10-28 | 1999-05-06 | The Australian National University | Isolated nucleic acid molecule encoding mammalian endoglucuronidase and uses therefor |
WO1999057153A1 (en) * | 1998-05-01 | 1999-11-11 | Insight Strategy & Marketing Ltd. | Heparanase specific molecular probes and their use in research and medical applications |
Non-Patent Citations (2)
Title |
---|
DATABASE EMBL [online] 28 October 1998 (1998-10-28), "qg97h02.x1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE:1843155 3', mRNA sequence", XP002215097, Database accession no. AI222323 * |
VLODAVSKY I ET AL: "Expression of heparanase by platelets and circulating cells of the immune system: Possible involvement in diapedesis and extravasation.", INVASION & METASTASIS, vol. 12, no. 2, 1992, pages 112 - 127, XP001106180, ISSN: 0251-1789 * |
Also Published As
Publication number | Publication date |
---|---|
AU777343B2 (en) | 2004-10-14 |
WO2001000643A2 (en) | 2001-01-04 |
IL146527A0 (en) | 2002-07-25 |
JP2003503070A (en) | 2003-01-28 |
NO20015526L (en) | 2001-12-18 |
MXPA01011708A (en) | 2003-09-10 |
AU5244800A (en) | 2001-01-31 |
NO20015526D0 (en) | 2001-11-12 |
PL362599A1 (en) | 2004-11-02 |
WO2001000643A3 (en) | 2005-02-24 |
CA2377498A1 (en) | 2001-01-04 |
KR20020028906A (en) | 2002-04-17 |
HUP0300901A2 (en) | 2003-07-28 |
CN1370178A (en) | 2002-09-18 |
EP1212341A1 (en) | 2002-06-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20011130 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20021016 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
D17D | Deferred search report published (deleted) | ||
17Q | First examination report despatched |
Effective date: 20051116 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: INSIGHT BIOPHARMACEUTICALS LTD. |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20061031 |