EP1210360A4 - Verbindungen, die beta-strränge von peptiden nachahmen - Google Patents

Verbindungen, die beta-strränge von peptiden nachahmen

Info

Publication number
EP1210360A4
EP1210360A4 EP00959312A EP00959312A EP1210360A4 EP 1210360 A4 EP1210360 A4 EP 1210360A4 EP 00959312 A EP00959312 A EP 00959312A EP 00959312 A EP00959312 A EP 00959312A EP 1210360 A4 EP1210360 A4 EP 1210360A4
Authority
EP
European Patent Office
Prior art keywords
strands
compounds useful
mimic peptide
peptide beta
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00959312A
Other languages
English (en)
French (fr)
Other versions
EP1210360A1 (de
Inventor
James S Nowick
Santanu Maitra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Publication of EP1210360A1 publication Critical patent/EP1210360A1/de
Publication of EP1210360A4 publication Critical patent/EP1210360A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP00959312A 1999-08-23 2000-08-23 Verbindungen, die beta-strränge von peptiden nachahmen Withdrawn EP1210360A4 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US15026099P 1999-08-23 1999-08-23
US150260P 1999-08-23
US15116999P 1999-08-27 1999-08-27
US151169P 1999-08-27
US15269699P 1999-09-07 1999-09-07
US152696P 1999-09-07
PCT/US2000/023049 WO2001014412A1 (en) 1999-08-23 2000-08-23 Compounds useful to mimic peptide beta-strands

Publications (2)

Publication Number Publication Date
EP1210360A1 EP1210360A1 (de) 2002-06-05
EP1210360A4 true EP1210360A4 (de) 2005-03-02

Family

ID=27386942

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00959312A Withdrawn EP1210360A4 (de) 1999-08-23 2000-08-23 Verbindungen, die beta-strränge von peptiden nachahmen

Country Status (3)

Country Link
EP (1) EP1210360A4 (de)
AU (1) AU7065500A (de)
WO (1) WO2001014412A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4235544B2 (ja) 2001-05-31 2009-03-11 アドライフ インコーポレーティッド 欠陥折畳み蛋白質センサー方法
US20050026165A1 (en) 2001-05-31 2005-02-03 Cindy Orser Detection of conformationally altered proteins and prions
JP5048522B2 (ja) 2005-02-15 2012-10-17 エイディーライフ インコーポレイティッド 誤って折り畳まれたタンパク質およびプリオンを検出する方法
DE102005015255A1 (de) 2005-04-04 2006-10-05 Merck Patent Gmbh Acylhydrazide
EP1826199A1 (de) * 2006-02-27 2007-08-29 Technische Universität Wien Modifizierte Aminosäuren
MX2009001079A (es) 2006-07-28 2009-02-10 Adlyfe Inc Sondas de peptido para diagnosis y terapeutica.
CN103588661A (zh) * 2012-08-17 2014-02-19 北京维德维康生物技术有限公司 尼卡巴嗪半抗原和人工抗原的制备
US20240279285A1 (en) * 2021-06-17 2024-08-22 The Regents Of The University Of California Rippled Antiparallel Cross-Beta Dimers and Related Materials, Compositions and Methods

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770773A (en) * 1994-04-14 1998-06-23 Zambon Group S.P.A. Process for the preparation of 5-amino-1,3-dioxanes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013878A2 (en) * 1991-02-07 1992-08-20 Board Of Trustees Of The University Of Illinois Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
US6020331A (en) * 1995-03-24 2000-02-01 Molecumetics, Ltd. β-sheet mimetics and use thereof as protease inhibitors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770773A (en) * 1994-04-14 1998-06-23 Zambon Group S.P.A. Process for the preparation of 5-amino-1,3-dioxanes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NOWICK JS ET AL.: "A Chemical Model of a Protein beta-Sheet Dimer", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 121, 31 August 1999 (1999-08-31), pages 8409 - 8410, XP002299821 *
NOWICK JS: "Chemical Models of Protein beta-Sheets", ACCOUNTS OF CHEMICAL RESEARCH, vol. 32, 21 January 1999 (1999-01-21), pages 287 - 296, XP002299820 *
See also references of WO0114412A1 *

Also Published As

Publication number Publication date
EP1210360A1 (de) 2002-06-05
WO2001014412A1 (en) 2001-03-01
AU7065500A (en) 2001-03-19

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20020319

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: MAITRA, SANTANU

Inventor name: NOWICK, JAMES, S.

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61K 38/06 B

Ipc: 7C 07K 5/02 A

Ipc: 7C 07C 243/38 B

Ipc: 7G 01N 33/68 B

A4 Supplementary search report drawn up and despatched

Effective date: 20050114

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