EP1210088A4 - 2-amino-benzoxazinones for the treatment of herpes simplex virus - Google Patents

2-amino-benzoxazinones for the treatment of herpes simplex virus

Info

Publication number
EP1210088A4
EP1210088A4 EP00948615A EP00948615A EP1210088A4 EP 1210088 A4 EP1210088 A4 EP 1210088A4 EP 00948615 A EP00948615 A EP 00948615A EP 00948615 A EP00948615 A EP 00948615A EP 1210088 A4 EP1210088 A4 EP 1210088A4
Authority
EP
European Patent Office
Prior art keywords
benzoxazinones
amino
treatment
herpes simplex
simplex virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00948615A
Other languages
German (de)
French (fr)
Other versions
EP1210088A1 (en
Inventor
Masashi Kawanishi
Wataru Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
GD Searle LLC
Original Assignee
Asahi Kasei Kogyo KK
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Kogyo KK, GD Searle LLC filed Critical Asahi Kasei Kogyo KK
Publication of EP1210088A1 publication Critical patent/EP1210088A1/en
Publication of EP1210088A4 publication Critical patent/EP1210088A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
EP00948615A 1999-07-12 2000-07-11 2-amino-benzoxazinones for the treatment of herpes simplex virus Withdrawn EP1210088A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14295699P 1999-07-12 1999-07-12
US142956P 1999-07-12
PCT/US2000/018817 WO2001003697A1 (en) 1999-07-12 2000-07-11 2-amino-benzoxazinones for the treatment of herpes simplex virus

Publications (2)

Publication Number Publication Date
EP1210088A1 EP1210088A1 (en) 2002-06-05
EP1210088A4 true EP1210088A4 (en) 2003-03-12

Family

ID=22501956

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00948615A Withdrawn EP1210088A4 (en) 1999-07-12 2000-07-11 2-amino-benzoxazinones for the treatment of herpes simplex virus

Country Status (11)

Country Link
EP (1) EP1210088A4 (en)
JP (1) JP2003504334A (en)
KR (1) KR20020046273A (en)
CN (1) CN1481245A (en)
AU (2) AU774370B2 (en)
BR (1) BR0012380A (en)
CA (1) CA2378014A1 (en)
HK (1) HK1046862A1 (en)
MX (1) MXPA02000485A (en)
WO (1) WO2001003697A1 (en)
ZA (1) ZA200200311B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2066662T3 (en) * 2006-09-21 2013-05-31 Kyorin Seiyaku Kk Serine hydrolase inhibitors
EP4144336A1 (en) * 2021-05-14 2023-03-08 The Procter & Gamble Company Wet wipes with a cellulosic substrate and gentle lotion

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996037485A1 (en) * 1995-05-24 1996-11-28 G.D. Searle & Co. 2-amino-benzoxazinones for the treatment of viral infections

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996037485A1 (en) * 1995-05-24 1996-11-28 G.D. Searle & Co. 2-amino-benzoxazinones for the treatment of viral infections

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ABOOD, NORMAN A. ET AL: "Inhibition of human cytomegalovirus protease by benzoxazinones and evidence of antiviral activity in cell culture", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (1997), 7(16), 2105-2108, XP004136393 *
PARLOW, JOHN J. ET AL: "Solution-phase parallel synthesis of a benzoxazinone library using complementary molecular reactivity and molecular recognition (CMR/R) purification technology", TETRAHEDRON (1998), 54(16), 4013-4031, XP004162177 *
See also references of WO0103697A1 *

Also Published As

Publication number Publication date
AU2004203884A1 (en) 2004-09-09
AU6208900A (en) 2001-01-30
CA2378014A1 (en) 2001-01-18
KR20020046273A (en) 2002-06-20
CN1481245A (en) 2004-03-10
HK1046862A1 (en) 2003-01-30
BR0012380A (en) 2002-08-27
EP1210088A1 (en) 2002-06-05
MXPA02000485A (en) 2004-09-10
JP2003504334A (en) 2003-02-04
ZA200200311B (en) 2003-01-14
WO2001003697A1 (en) 2001-01-18
AU774370B2 (en) 2004-06-24

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