EP1206477A4 - Cloning of the streptomyces avermitilis genes for glycosylation of avermectin aglycones - Google Patents
Cloning of the streptomyces avermitilis genes for glycosylation of avermectin aglyconesInfo
- Publication number
- EP1206477A4 EP1206477A4 EP00950713A EP00950713A EP1206477A4 EP 1206477 A4 EP1206477 A4 EP 1206477A4 EP 00950713 A EP00950713 A EP 00950713A EP 00950713 A EP00950713 A EP 00950713A EP 1206477 A4 EP1206477 A4 EP 1206477A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- glycosylation
- cloning
- streptomyces avermitilis
- avermectin aglycones
- avermitilis genes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14669999P | 1999-07-30 | 1999-07-30 | |
US146699P | 1999-07-30 | ||
PCT/US2000/020331 WO2001009155A1 (en) | 1999-07-30 | 2000-07-26 | Cloning of the streptomyces avermitilis genes for glycosylation of avermectin aglycones |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1206477A1 EP1206477A1 (en) | 2002-05-22 |
EP1206477A4 true EP1206477A4 (en) | 2004-11-24 |
Family
ID=22518585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00950713A Withdrawn EP1206477A4 (en) | 1999-07-30 | 2000-07-26 | Cloning of the streptomyces avermitilis genes for glycosylation of avermectin aglycones |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1206477A4 (en) |
JP (1) | JP2003506022A (en) |
CA (1) | CA2380639A1 (en) |
WO (1) | WO2001009155A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000245457A (en) * | 1999-02-24 | 2000-09-12 | Kitasato Inst:The | Avermectin aglycon synthetase |
US20030171562A1 (en) * | 2001-04-26 | 2003-09-11 | Farnet Chris M. | Genes and proteins for the biosynthesis of polyketides |
EP1524318A1 (en) * | 2001-04-26 | 2005-04-20 | Ecopia Biosciences Inc. | Genes and proteins for the biosynthesis of polyketides |
US7630836B2 (en) | 2001-05-30 | 2009-12-08 | The Kitasato Institute | Polynucleotides |
EP1477563A3 (en) | 2003-05-16 | 2004-11-24 | Wyeth | Cloning genes from streptomyces cyaneogriseus subsp.noncyanogenus for biosynthesis of antibiotics and methods of use |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0391594A2 (en) * | 1989-03-31 | 1990-10-10 | Merck & Co. Inc. | Cloning genes from streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6822696A (en) * | 1995-08-30 | 1997-03-19 | Novartis Ag | Staurosporin biosynthesis gene clusters |
-
2000
- 2000-07-26 CA CA002380639A patent/CA2380639A1/en not_active Abandoned
- 2000-07-26 JP JP2001513962A patent/JP2003506022A/en not_active Withdrawn
- 2000-07-26 EP EP00950713A patent/EP1206477A4/en not_active Withdrawn
- 2000-07-26 WO PCT/US2000/020331 patent/WO2001009155A1/en not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0391594A2 (en) * | 1989-03-31 | 1990-10-10 | Merck & Co. Inc. | Cloning genes from streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
Non-Patent Citations (5)
Title |
---|
DATABASE EMBL 10 February 1999 (1999-02-10), "Streptomyces cyanogenus landomycin biosynthetic gene cluster, complete sequence", XP002298610, Database accession no. AF080235 * |
MACNEIL D J ET AL: "ANALYSIS OF STREPTOMYCES AVERMITILIS GENES REQUIRED FOR AVERMECTIN BIOSYNTHESIS UTILIZING A NOVEL INTEGRATION VECTOR", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 111, no. 1, 1992, pages 61 - 68, XP001180832, ISSN: 0378-1119 * |
OCCI J L ET AL: "CLONING AND SEQUENCING A 5.2 KB REGION FROM STREPTOMYCES-AVERMITILIS INVOLVED IN GLYCOSYLATION OF AVERMECTIN", ABSTRACTS OF THE ANNUAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 90, 1990, 90TH ANNUAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY 1990, ANAHEIM, CALIFORNIA, USA, MAY 13-, pages 268, XP008036043, ISSN: 0094-8519 * |
SCHULMAN M D ET AL: "PURIFICATION AND IDENTIFICATION OF D-TDP-OLEANDROSE THE PRECURSOR OF THE OLEANDROSE UNITS OF THE AVERMECTINS", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 265, no. 28, 1990, pages 16965 - 16970, XP002298197, ISSN: 0021-9258 * |
See also references of WO0109155A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP2003506022A (en) | 2003-02-18 |
WO2001009155A1 (en) | 2001-02-08 |
CA2380639A1 (en) | 2001-02-08 |
EP1206477A1 (en) | 2002-05-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020228 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20041013 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: 7C 12R 1:465 J Ipc: 7C 12N 9/00 J Ipc: 7C 12N 9/00 A Ipc: 7C 12N 15/52 B |
|
17Q | First examination report despatched |
Effective date: 20050307 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20050920 |