EP1198468A4 - Proteines d'enveloppe virale stabilisee et utilisations - Google Patents
Proteines d'enveloppe virale stabilisee et utilisationsInfo
- Publication number
- EP1198468A4 EP1198468A4 EP00944801A EP00944801A EP1198468A4 EP 1198468 A4 EP1198468 A4 EP 1198468A4 EP 00944801 A EP00944801 A EP 00944801A EP 00944801 A EP00944801 A EP 00944801A EP 1198468 A4 EP1198468 A4 EP 1198468A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- envelope proteins
- viral envelope
- stabilized viral
- stabilized
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108010003533 Viral Envelope Proteins Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US340992 | 1989-04-20 | ||
US34099299A | 1999-06-25 | 1999-06-25 | |
PCT/US2000/017267 WO2001000648A1 (fr) | 1999-06-25 | 2000-06-23 | Proteines d'enveloppe virale stabilisee et utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1198468A1 EP1198468A1 (fr) | 2002-04-24 |
EP1198468A4 true EP1198468A4 (fr) | 2003-07-30 |
Family
ID=23335807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00944801A Withdrawn EP1198468A4 (fr) | 1999-06-25 | 2000-06-23 | Proteines d'enveloppe virale stabilisee et utilisations |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1198468A4 (fr) |
JP (1) | JP2003509013A (fr) |
AU (1) | AU782123B2 (fr) |
CA (1) | CA2370517A1 (fr) |
HK (1) | HK1046911A1 (fr) |
WO (1) | WO2001000648A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6710173B1 (en) | 1999-06-25 | 2004-03-23 | Progenics Pharmaceuticals, Inc. | Stabilized viral envelope proteins and uses thereof |
JP2005502350A (ja) * | 2001-09-06 | 2005-01-27 | プロジェニクス・ファーマスーティカルズ・インコーポレイテッド | ヒト免疫不全ウイルスエンベロープ糖タンパク質変異体およびその使用 |
EP1463521A4 (fr) * | 2001-12-17 | 2009-06-24 | Us Gov Health & Human Serv | Inhibiteur de gp41 |
CA2481980A1 (fr) * | 2002-04-05 | 2003-10-23 | Progenics Pharmaceuticals, Inc. | Glycoproteines de l'enveloppe du virus d'immunodeficience humaine liees a des particules, compositions et procedes associes |
AU2004247146A1 (en) * | 2003-06-12 | 2004-12-23 | Vaxgen, Inc. | HIV-1 envelope glycoproteins having unusual disulfide structure |
KR100560468B1 (ko) | 2003-09-16 | 2006-03-13 | 삼성에스디아이 주식회사 | 화상 표시 장치와 그 표시 패널 |
CN101366205B (zh) * | 2006-03-17 | 2012-04-04 | 华为技术有限公司 | 一种在基于ofdma的通信系统中实现软切换的方法及装置 |
EP2073840A4 (fr) | 2006-10-23 | 2010-10-27 | Progenics Pharm Inc | Polypeptides d'enveloppe gp140 modifiés en provenance d'isolats du vih-1, compositions, complexes trimériques et utilisations de ceux-ci |
US20150183835A1 (en) * | 2012-06-18 | 2015-07-02 | Novartis Ag | Stabilized gp120 |
MX2021004273A (es) | 2018-10-17 | 2021-12-10 | Glaxosmithkline Biologicals Sa | Proteinas de citomegalovirus modificadas y complejos estabilizados. |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5886163A (en) * | 1993-03-26 | 1999-03-23 | Progenics Pharmaceuticals, Inc. | HIV-1 antigens, antibody compositions related thereto, and therapeutic and prophylactic uses thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05506669A (ja) * | 1990-09-25 | 1993-09-30 | ペプテック (ユーケイ) リミテッド | エイズ治療法及びワクチン |
-
2000
- 2000-06-23 WO PCT/US2000/017267 patent/WO2001000648A1/fr active IP Right Grant
- 2000-06-23 JP JP2001507055A patent/JP2003509013A/ja active Pending
- 2000-06-23 CA CA002370517A patent/CA2370517A1/fr not_active Abandoned
- 2000-06-23 EP EP00944801A patent/EP1198468A4/fr not_active Withdrawn
- 2000-06-23 AU AU58842/00A patent/AU782123B2/en not_active Ceased
-
2002
- 2002-10-23 HK HK02107688.0A patent/HK1046911A1/zh unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5886163A (en) * | 1993-03-26 | 1999-03-23 | Progenics Pharmaceuticals, Inc. | HIV-1 antigens, antibody compositions related thereto, and therapeutic and prophylactic uses thereof |
Non-Patent Citations (7)
Title |
---|
BINLEY J M ET AL: "A RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 ENVELOPE GLYCOPROTEIN COMPLEX STABILIZED BY AN INTERMOLECULAR DISULFIDE BOND BETWEEN THE GP120 AND GP41 SUBUNITS IS AN ANTIGENIC MIMIC OF THE TRIMERIC VIRION-ASSOCIATED STRUCTURE", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 74, no. 2, January 2000 (2000-01-01), pages 627 - 643, XP002939087, ISSN: 0022-538X * |
BURTON DENNIS R ET AL: "Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody.", SCIENCE (WASHINGTON D C), vol. 266, no. 5187, 1994, pages 1024 - 1027, XP001147878, ISSN: 0036-8075 * |
FARZAN M ET AL: "Stabilization of human immunodeficiency virus type 1 envelope glycoprotei trimers by disulfide bonds introduced into the gp41 glycoprotein ectodomain", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 72, no. 9, September 1998 (1998-09-01), pages 7620 - 7625, XP002097559, ISSN: 0022-538X * |
LABRANCHE C C ET AL: "Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus.", JOURNAL OF VIROLOGY. UNITED STATES NOV 1994, vol. 68, no. 11, November 1994 (1994-11-01), pages 7665 - 7667, XP009010815, ISSN: 0022-538X * |
LABRANCHE CELIA C ET AL: "Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus.", JOURNAL OF VIROLOGY, vol. 68, no. 9, 1994, pages 5509 - 5522, XP009010814, ISSN: 0022-538X * |
See also references of WO0100648A1 * |
TRKOLA ALEXANDRA ET AL: "Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp 120 glycoprotein of human immunodeficiency virus type 1.", JOURNAL OF VIROLOGY, vol. 70, no. 2, 1996, pages 1100 - 1108, XP002241179, ISSN: 0022-538X * |
Also Published As
Publication number | Publication date |
---|---|
EP1198468A1 (fr) | 2002-04-24 |
CA2370517A1 (fr) | 2001-01-04 |
WO2001000648A1 (fr) | 2001-01-04 |
HK1046911A1 (zh) | 2003-01-30 |
AU782123B2 (en) | 2005-07-07 |
JP2003509013A (ja) | 2003-03-11 |
AU5884200A (en) | 2001-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020125 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: BINLEY, JAMES, M. Inventor name: MOORE, JOHN, P., DEPT OF MICROBIOLOGY AND IMMUNOL Inventor name: SCHUELKE, NORBERT Inventor name: MADDON, PAUL, J. Inventor name: OLSON, WILLIAM, C. |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20030611 |
|
17Q | First examination report despatched |
Effective date: 20051219 |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1046911 Country of ref document: HK |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20120503 |