EP1194171A2 - Materiaux hydrogels produisant du monoxyde d'azote - Google Patents
Materiaux hydrogels produisant du monoxyde d'azoteInfo
- Publication number
- EP1194171A2 EP1194171A2 EP00959750A EP00959750A EP1194171A2 EP 1194171 A2 EP1194171 A2 EP 1194171A2 EP 00959750 A EP00959750 A EP 00959750A EP 00959750 A EP00959750 A EP 00959750A EP 1194171 A2 EP1194171 A2 EP 1194171A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- macromer
- regions
- region
- tissue
- macromer composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Medicinal Preparation (AREA)
- Colloid Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15205499P | 1999-09-02 | 1999-09-02 | |
US152054P | 1999-09-02 | ||
PCT/US2000/024058 WO2001015738A2 (fr) | 1999-09-02 | 2000-09-01 | Materiaux hydrogels produisant du monoxyde d'azote |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1194171A2 true EP1194171A2 (fr) | 2002-04-10 |
Family
ID=22541347
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00959750A Withdrawn EP1194171A2 (fr) | 1999-09-02 | 2000-09-01 | Materiaux hydrogels produisant du monoxyde d'azote |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1194171A2 (fr) |
AU (1) | AU7101600A (fr) |
CA (1) | CA2353531A1 (fr) |
CZ (1) | CZ20011899A3 (fr) |
IL (1) | IL143305A0 (fr) |
MX (1) | MXPA01005338A (fr) |
WO (1) | WO2001015738A2 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7052711B2 (en) | 1999-09-02 | 2006-05-30 | Rice University | Nitric oxide-producing hydrogel materials |
US7279176B1 (en) | 1999-09-02 | 2007-10-09 | Rice University | Nitric oxide-producing hydrogel materials |
WO2001087312A1 (fr) * | 2000-05-18 | 2001-11-22 | Genetix Pharmaceuticals, Inc. | Utilisation de polymeres polyethyleneglycols (peg) dans la stimulation de l'angiogenese |
JP4841066B2 (ja) * | 2000-09-01 | 2011-12-21 | ライスユニバーシティ | 酸化窒素生成ヒドロゲル物質 |
CA2833997C (fr) | 2001-09-05 | 2017-09-26 | Geno Llc | Methode et appareil de production d'oxyde nitrique |
WO2003092700A1 (fr) | 2002-04-29 | 2003-11-13 | Gmp Oxycell, Inc. | Inositol pyrophosphates et procede d'utilisation desdits composes |
CA2487720A1 (fr) * | 2002-06-03 | 2003-12-11 | Alnis Biosciences, Inc. | Agent therapeutique contenant des nanoarticles polymeriques |
US7618594B2 (en) | 2004-08-18 | 2009-11-17 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
AU2005277397B2 (en) | 2004-08-18 | 2011-08-25 | VERO Biotech LLC. | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
EP3556401A1 (fr) | 2005-05-27 | 2019-10-23 | The University of North Carolina at Chapel Hill | Particules libérant de l'oxyde nitrique pour thérapie à base d'oxyde nitrique et applications biomédicales |
JP5575489B2 (ja) | 2007-03-23 | 2014-08-20 | ゲノ エルエルシー | 二酸化窒素(no2)から酸化窒素(no)への変換 |
AU2009209181B2 (en) | 2008-01-28 | 2014-01-16 | VERO Biotech LLC. | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
US8607785B2 (en) | 2008-08-21 | 2013-12-17 | Geno Llc | Systems and devices for generating nitric oxide |
US8613958B2 (en) | 2009-06-22 | 2013-12-24 | Geno Llc | Nitric oxide therapies |
WO2011022652A1 (fr) | 2009-08-21 | 2011-02-24 | Novan, Inc. | Gels topiques |
BR112012003804B1 (pt) | 2009-08-21 | 2019-02-19 | Novan, Inc. | Curativo para ferimentos, método para formar um curativo para ferimentos, e, kit de curativo para ferimento |
AU2010321707B2 (en) | 2009-11-20 | 2016-03-17 | VERO Biotech LLC. | Nitric oxide delivery system |
US8591876B2 (en) | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
WO2012118829A2 (fr) | 2011-02-28 | 2012-09-07 | Novan, Inc. | Xérogels libérant de l'oxyde nitrique modifiés par des groupements s-nitrosothiols tertiaires et procédés d'utilisation associés |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5797887A (en) * | 1996-08-27 | 1998-08-25 | Novovasc Llc | Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5910316A (en) * | 1992-08-24 | 1999-06-08 | The United States Of America, As Represented By The Department Of Health And Human Services | Use of nitric oxide-releasing agents to treat impotency |
US5691423A (en) * | 1992-08-24 | 1997-11-25 | The United States Of America As Represented By The Department Of Health And Human Services | Polysaccharide-bound nitric oxide-nucleophile adducts |
HUP9801673A1 (hu) * | 1998-07-24 | 2000-08-28 | CYCLOLAB, Ciklodextrin Kutató-Fejlesztő Kft. | Helyi vérbőséget fokozó gyógyszerkészítmények előállítása és alkalmazása |
-
2000
- 2000-09-01 EP EP00959750A patent/EP1194171A2/fr not_active Withdrawn
- 2000-09-01 CA CA002353531A patent/CA2353531A1/fr not_active Abandoned
- 2000-09-01 IL IL14330500A patent/IL143305A0/xx unknown
- 2000-09-01 AU AU71016/00A patent/AU7101600A/en not_active Abandoned
- 2000-09-01 MX MXPA01005338A patent/MXPA01005338A/es unknown
- 2000-09-01 WO PCT/US2000/024058 patent/WO2001015738A2/fr not_active Application Discontinuation
- 2000-09-01 CZ CZ20011899A patent/CZ20011899A3/cs unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5797887A (en) * | 1996-08-27 | 1998-08-25 | Novovasc Llc | Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation |
Also Published As
Publication number | Publication date |
---|---|
WO2001015738A3 (fr) | 2002-01-31 |
IL143305A0 (en) | 2002-04-21 |
AU7101600A (en) | 2001-03-26 |
CZ20011899A3 (cs) | 2001-11-14 |
CA2353531A1 (fr) | 2001-03-08 |
MXPA01005338A (es) | 2003-07-14 |
WO2001015738A2 (fr) | 2001-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20010906 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT |
|
AX | Request for extension of the european patent |
Free format text: AL PAYMENT 20010601;LT PAYMENT 20010601;LV PAYMENT 20010601;MK PAYMENT 20010601;RO PAYMENT 20010601;SI PAYMENT 20010601 |
|
17Q | First examination report despatched |
Effective date: 20030708 |
|
17Q | First examination report despatched |
Effective date: 20030708 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20071120 |