EP1180058A1 - Combinations of gaba analogs and tricyclic compounds to treat depression - Google Patents
Combinations of gaba analogs and tricyclic compounds to treat depressionInfo
- Publication number
- EP1180058A1 EP1180058A1 EP00913490A EP00913490A EP1180058A1 EP 1180058 A1 EP1180058 A1 EP 1180058A1 EP 00913490 A EP00913490 A EP 00913490A EP 00913490 A EP00913490 A EP 00913490A EP 1180058 A1 EP1180058 A1 EP 1180058A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- formula
- gabapentin
- hydrogen
- composition
- gaba analog
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/415—1,2-Diazoles
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Definitions
- the invention includes treating depression with a compound of Formula II.
- R ⁇ is a straight or branched alkyl of from 1 to 6 carbon atoms, phenyl, or
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Description
Claims
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12857199P | 1999-04-09 | 1999-04-09 | |
US128571P | 1999-04-09 | ||
PCT/US2000/003983 WO2000061234A1 (en) | 1999-04-09 | 2000-02-16 | Combinations of gaba analogs and tricyclic compounds to treat depression |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1180058A1 true EP1180058A1 (en) | 2002-02-20 |
Family
ID=22435960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00913490A Withdrawn EP1180058A1 (en) | 1999-04-09 | 2000-02-16 | Combinations of gaba analogs and tricyclic compounds to treat depression |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1180058A1 (en) |
JP (1) | JP2002541224A (en) |
KR (1) | KR20010108466A (en) |
AU (1) | AU3492900A (en) |
CA (1) | CA2367494A1 (en) |
HU (1) | HUP0200733A3 (en) |
IL (1) | IL145736A0 (en) |
NZ (1) | NZ514401A (en) |
TR (1) | TR200102850T2 (en) |
WO (1) | WO2000061234A1 (en) |
ZA (1) | ZA200108259B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100491282B1 (en) | 1996-07-24 | 2005-05-24 | 워너-램버트 캄파니 엘엘씨 | Isobutylgaba and Its Derivatives for the Treatment of Pain |
EP1471909A4 (en) * | 2002-01-16 | 2007-07-25 | Endo Pharmaceuticals Inc | Pharmaceutical composition and method for treating disorders of the central nervous system |
RU2006107534A (en) * | 2003-09-12 | 2007-09-20 | Уорнер-Ламберт Компани Ллс (Us) | COMBINATION INCLUDING ALPHA-2-DELTA-LIGAND AND AND SSRI AND / OR SNRI FOR THE TREATMENT OF DEPRESSION AND ANXIETY DISORDER |
CN1849153A (en) * | 2003-09-12 | 2006-10-18 | 辉瑞大药厂 | Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2410821A1 (en) * | 1974-03-07 | 1975-09-18 | Hoechst Ag | PHARMACEUTICAL COMBINATION PREPARATIONS WITH PSYCHOTROPIC EFFECT AND METHOD FOR THEIR PRODUCTION |
FR2453643A2 (en) * | 1977-06-24 | 1980-11-07 | Synthelabo | PHARMACEUTICAL COMPOSITIONS ACTIVE ON THE CENTRAL NERVOUS SYSTEM |
US5025035A (en) * | 1990-10-12 | 1991-06-18 | Warner-Lambert Company | Method of treating depression |
AU9137091A (en) * | 1990-11-27 | 1992-06-25 | Northwestern University | Gaba and l-glutamic acid analogs for antiseizure treatment |
EP0726073A3 (en) * | 1995-02-10 | 1998-07-08 | Eduardo Samuel Bleiweiss | Pharmaceutical compositions containing at least one of haloperidol, imipramine or trifluoroperazine |
-
2000
- 2000-02-16 TR TR2001/02850T patent/TR200102850T2/en unknown
- 2000-02-16 EP EP00913490A patent/EP1180058A1/en not_active Withdrawn
- 2000-02-16 KR KR1020017012788A patent/KR20010108466A/en not_active Application Discontinuation
- 2000-02-16 IL IL14573600A patent/IL145736A0/en unknown
- 2000-02-16 AU AU34929/00A patent/AU3492900A/en not_active Abandoned
- 2000-02-16 NZ NZ514401A patent/NZ514401A/en unknown
- 2000-02-16 HU HU0200733A patent/HUP0200733A3/en unknown
- 2000-02-16 WO PCT/US2000/003983 patent/WO2000061234A1/en not_active Application Discontinuation
- 2000-02-16 JP JP2000610562A patent/JP2002541224A/en active Pending
- 2000-02-16 CA CA002367494A patent/CA2367494A1/en not_active Abandoned
-
2001
- 2001-10-08 ZA ZA200108259A patent/ZA200108259B/en unknown
Non-Patent Citations (1)
Title |
---|
See references of WO0061234A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU3492900A (en) | 2000-11-14 |
HUP0200733A2 (en) | 2002-07-29 |
NZ514401A (en) | 2003-10-31 |
TR200102850T2 (en) | 2002-03-21 |
JP2002541224A (en) | 2002-12-03 |
WO2000061234A1 (en) | 2000-10-19 |
KR20010108466A (en) | 2001-12-07 |
HUP0200733A3 (en) | 2003-04-28 |
CA2367494A1 (en) | 2000-10-19 |
IL145736A0 (en) | 2002-07-25 |
ZA200108259B (en) | 2003-03-26 |
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