EP1165111A4 - Method for pr-39 peptide regulated stimulation of angiogenesis - Google Patents

Method for pr-39 peptide regulated stimulation of angiogenesis

Info

Publication number
EP1165111A4
EP1165111A4 EP00919442A EP00919442A EP1165111A4 EP 1165111 A4 EP1165111 A4 EP 1165111A4 EP 00919442 A EP00919442 A EP 00919442A EP 00919442 A EP00919442 A EP 00919442A EP 1165111 A4 EP1165111 A4 EP 1165111A4
Authority
EP
European Patent Office
Prior art keywords
angiogenesis
peptide regulated
regulated stimulation
stimulation
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00919442A
Other languages
German (de)
French (fr)
Other versions
EP1165111A1 (en
Inventor
Michael Simons
Youhe Gao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beth Israel Deaconess Medical Center Inc
Original Assignee
Beth Israel Deaconess Medical Center Inc
Beth Israel Hospital Association
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/276,868 external-priority patent/US7202217B1/en
Application filed by Beth Israel Deaconess Medical Center Inc, Beth Israel Hospital Association filed Critical Beth Israel Deaconess Medical Center Inc
Publication of EP1165111A1 publication Critical patent/EP1165111A1/en
Publication of EP1165111A4 publication Critical patent/EP1165111A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
EP00919442A 1999-03-26 2000-03-16 Method for pr-39 peptide regulated stimulation of angiogenesis Withdrawn EP1165111A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/276,868 US7202217B1 (en) 1998-10-13 1999-03-26 Method for PR-39 peptide regulated stimulation of angiogenesis
US276868 1999-03-26
PCT/US2000/007050 WO2000057895A1 (en) 1999-03-26 2000-03-16 Method for pr-39 peptide regulated stimulation of angiogenesis

Publications (2)

Publication Number Publication Date
EP1165111A1 EP1165111A1 (en) 2002-01-02
EP1165111A4 true EP1165111A4 (en) 2004-11-03

Family

ID=23058406

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00919442A Withdrawn EP1165111A4 (en) 1999-03-26 2000-03-16 Method for pr-39 peptide regulated stimulation of angiogenesis

Country Status (4)

Country Link
EP (1) EP1165111A4 (en)
AU (1) AU4013200A (en)
CA (1) CA2368638A1 (en)
WO (1) WO2000057895A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6748258B1 (en) 1999-11-05 2004-06-08 Scimed Life Systems, Inc. Method and devices for heart treatment
US6676679B1 (en) 1999-11-05 2004-01-13 Boston Scientific Corporation Method and apparatus for recurrent demand injury in stimulating angiogenesis
CA2397955A1 (en) * 1999-12-29 2001-07-05 Beth Israel Deaconess Medical Center Method for pr-39 peptide mediated selective inhibition of i.kappa.b.alpha. degradation
EP1267729A2 (en) 2000-03-23 2003-01-02 SciMed Life Systems, Inc. Pressure sensor for therapeutic delivery device and method
US7214223B2 (en) 2000-03-24 2007-05-08 Boston Scientific Scimed, Inc. Photoatherolytic catheter apparatus and method
WO2002000278A2 (en) 2000-06-26 2002-01-03 Microheart, Inc. Method and apparatus for treating ischemic tissue
EP1313327A1 (en) 2001-11-14 2003-05-21 Deutsche Thomson-Brandt Gmbh Digital video recorder and methods for digital recording
SE0300207D0 (en) * 2003-01-29 2003-01-29 Karolinska Innovations Ab New use and composition
ES2426441T3 (en) 2004-10-18 2013-10-23 Basf Beauty Care Solutions France S.A.S. Oligopeptides and their use in cosmetics
US7939499B2 (en) 2005-05-03 2011-05-10 Trustees Of Dartmouth College Method for increasing cardiac mass and performance

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996009322A2 (en) * 1994-09-22 1996-03-28 Children's Medical Center Corporation Synducin mediated modulation of tissue repair
WO1996032129A1 (en) * 1995-04-10 1996-10-17 Kansas State University Research Foundation Synthetic peptides that inhibit leukocyte superoxide anion production and/or attract leukocytes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996009322A2 (en) * 1994-09-22 1996-03-28 Children's Medical Center Corporation Synducin mediated modulation of tissue repair
WO1996032129A1 (en) * 1995-04-10 1996-10-17 Kansas State University Research Foundation Synthetic peptides that inhibit leukocyte superoxide anion production and/or attract leukocytes

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
GAO Y ET AL: "Inhibition of ubiquitin-proteasome pathway-mediated I-kappaBalpha degradation by a naturally occuring antibacterial peptide", JOURNAL OF CLINICAL INVESTIGATION, NEW YORK, NY, US, vol. 106, no. 3, August 2000 (2000-08-01), pages 439 - 448, XP002180614, ISSN: 0021-9738 *
GAO Y ET AL: "PR39 INTERACTS WITH PROTEASOME AND MODULATES HIF-1ALPHA LEVEL IN ECV CELLS", MOLECULAR BIOLOGY OF THE CELL, BETHESDA, MD, US, vol. 9, no. SUPPL, November 1998 (1998-11-01), pages 123A, XP008033931, ISSN: 1059-1524 *
LI J ET AL: "CARDIAC-SPECIFIC OVEREXPRESSION OF PR-39 INDUCES ANGIOGENESIS, MYOCARDIAL HYPERTROPHY AND INCREASED MICROVASCULAR REACTIVITY", CIRCULATION, AMERICAN HEART ASSOCIATION, DALLAS, TX, US, vol. 98, no. 17, October 1998 (1998-10-01), pages 1794, XP002929855, ISSN: 0009-7322 *
LI J ET AL: "MACROPHAGE-DEPENDENT REGULATION OF SYNDECAN GENE EXPRESSION", CIRCULATION RESEARCH, GRUNE AND STRATTON, BALTIMORE, US, vol. 81, no. 5, November 1997 (1997-11-01), pages 785 - 796, XP008033955, ISSN: 0009-7330 *
LI J ET AL: "PR39, a peptide regulator of angiogenesis", NATURE MEDICINE, NATURE AMERICA, NEW YORK, US, vol. 6, no. 1, January 2000 (2000-01-01), pages 49 - 55, XP002968105, ISSN: 1078-8956 *
See also references of WO0057895A1 *

Also Published As

Publication number Publication date
WO2000057895A1 (en) 2000-10-05
AU4013200A (en) 2000-10-16
CA2368638A1 (en) 2000-10-05
EP1165111A1 (en) 2002-01-02

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Legal Events

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RTI1 Title (correction)

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