EP1135023A4 - Aminobenzisoxazole compounds and libraries thereof - Google Patents

Aminobenzisoxazole compounds and libraries thereof

Info

Publication number
EP1135023A4
EP1135023A4 EP99958891A EP99958891A EP1135023A4 EP 1135023 A4 EP1135023 A4 EP 1135023A4 EP 99958891 A EP99958891 A EP 99958891A EP 99958891 A EP99958891 A EP 99958891A EP 1135023 A4 EP1135023 A4 EP 1135023A4
Authority
EP
European Patent Office
Prior art keywords
libraries
aminobenzisoxazole compounds
aminobenzisoxazole
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99958891A
Other languages
German (de)
French (fr)
Other versions
EP1135023A1 (en
Inventor
Michael Robert Wiley
Savatore Donato Lepore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of EP1135023A1 publication Critical patent/EP1135023A1/en
Publication of EP1135023A4 publication Critical patent/EP1135023A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EP99958891A 1998-11-12 1999-11-12 Aminobenzisoxazole compounds and libraries thereof Withdrawn EP1135023A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US10820898P 1998-11-12 1998-11-12
US108208P 1998-11-12
US12915199P 1999-04-14 1999-04-14
US129151P 1999-04-14
US14549299P 1999-07-22 1999-07-22
US145492P 1999-07-22
PCT/US1999/026635 WO2000027199A1 (en) 1998-11-12 1999-11-12 Aminobenzisoxazole compounds and libraries thereof

Publications (2)

Publication Number Publication Date
EP1135023A1 EP1135023A1 (en) 2001-09-26
EP1135023A4 true EP1135023A4 (en) 2003-03-05

Family

ID=27380448

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99958891A Withdrawn EP1135023A4 (en) 1998-11-12 1999-11-12 Aminobenzisoxazole compounds and libraries thereof

Country Status (3)

Country Link
EP (1) EP1135023A4 (en)
AU (1) AU1616600A (en)
WO (1) WO2000027199A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6569879B2 (en) * 2000-02-18 2003-05-27 Merck & Co., Inc. Aryloxyacetic acids for diabetes and lipid disorders
DE102005038947A1 (en) 2005-05-18 2006-11-30 Grünenthal GmbH Substituted benzo [d] isoxazol-3-yl-amine compounds and their use in medicaments
AU2020290351A1 (en) 2019-06-11 2022-02-03 Fresenius Medical Care Holdings, Inc. Systems and methods for measuring electrical characteristic of medical fluids

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0816376A1 (en) * 1996-06-25 1998-01-07 Eli Lilly And Company Trombin inhibitors as anticoagulant agents
WO1998057951A1 (en) * 1997-06-19 1998-12-23 Du Pont Pharmaceuticals Company NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS
WO2000026210A1 (en) * 1998-10-30 2000-05-11 Merck & Co., Inc. Thrombin inhibitors
WO2000027627A1 (en) * 1998-11-12 2000-05-18 Eli Lilly And Company Aryloxime linkers in the solid-phase synthesis of 3-aminobenzisoxazoles

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455274A (en) * 1992-12-09 1995-10-03 Ciba-Geigy Corporation Hydroxyamidine derivatives
ES2208690T3 (en) * 1994-08-30 2004-06-16 Sankyo Company Limited ISOXAZOL
JP2891187B2 (en) * 1995-06-22 1999-05-17 信越半導体株式会社 Wire saw device and cutting method
AU4153497A (en) * 1996-08-26 1998-03-19 Eli Lilly And Company Combinatorial process for preparing substituted thiophene libraries

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0816376A1 (en) * 1996-06-25 1998-01-07 Eli Lilly And Company Trombin inhibitors as anticoagulant agents
WO1998057951A1 (en) * 1997-06-19 1998-12-23 Du Pont Pharmaceuticals Company NOVEL GUANIDINE MIMICS AS FACTOR Xa INHIBITORS
WO2000026210A1 (en) * 1998-10-30 2000-05-11 Merck & Co., Inc. Thrombin inhibitors
WO2000027627A1 (en) * 1998-11-12 2000-05-18 Eli Lilly And Company Aryloxime linkers in the solid-phase synthesis of 3-aminobenzisoxazoles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO0027199A1 *

Also Published As

Publication number Publication date
AU1616600A (en) 2000-05-29
EP1135023A1 (en) 2001-09-26
WO2000027199A1 (en) 2000-05-18

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Legal Events

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