EP1115412A4 - Neuroimmunophilins for selective neuronal radioprotection - Google Patents

Neuroimmunophilins for selective neuronal radioprotection

Info

Publication number
EP1115412A4
EP1115412A4 EP98948530A EP98948530A EP1115412A4 EP 1115412 A4 EP1115412 A4 EP 1115412A4 EP 98948530 A EP98948530 A EP 98948530A EP 98948530 A EP98948530 A EP 98948530A EP 1115412 A4 EP1115412 A4 EP 1115412A4
Authority
EP
European Patent Office
Prior art keywords
neuroimmunophilins
radioprotection
selective neuronal
neuronal
selective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98948530A
Other languages
German (de)
French (fr)
Other versions
EP1115412A1 (en
Inventor
Marcus Keep
Eskil Elmer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1115412A1 publication Critical patent/EP1115412A1/en
Publication of EP1115412A4 publication Critical patent/EP1115412A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EP98948530A 1998-09-23 1998-09-23 Neuroimmunophilins for selective neuronal radioprotection Withdrawn EP1115412A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/020040 WO2000016794A1 (en) 1998-09-23 1998-09-23 Neuroimmunophilins for selective neuronal radioprotection

Publications (2)

Publication Number Publication Date
EP1115412A1 EP1115412A1 (en) 2001-07-18
EP1115412A4 true EP1115412A4 (en) 2004-12-15

Family

ID=22267931

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98948530A Withdrawn EP1115412A4 (en) 1998-09-23 1998-09-23 Neuroimmunophilins for selective neuronal radioprotection

Country Status (10)

Country Link
EP (1) EP1115412A4 (en)
JP (1) JP2002526453A (en)
CN (1) CN1322136A (en)
AP (1) AP2001002113A0 (en)
AU (1) AU766095B2 (en)
BR (1) BR9816047A (en)
CA (1) CA2345378A1 (en)
HK (1) HK1040617A1 (en)
IL (1) IL142120A0 (en)
WO (1) WO2000016794A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK286421B6 (en) * 2000-10-31 2008-09-05 Pharma Mar, S. A. Formulation of kahalalide F, kit, reconstituted and diluted solution comprising formulation and use
WO2005103255A1 (en) * 2004-03-25 2005-11-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Formylpeptide receptor (fpr) as a target for anti-malignant glioma therapy
US11745029B2 (en) 2018-05-30 2023-09-05 Zap Surgical Systems, Inc. Radiosurgical neuromodulation close to critical structures

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022104A1 (en) * 1995-01-20 1996-07-25 Elmer Eskil Treatment of cerebral ischemia and cerebral damage with neuroprotective agent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3089350B2 (en) * 1995-11-20 2000-09-18 ギルフォード ファーマシューティカルズ インコーポレイテッド Inhibitors of cyclophilin rotamase activity

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022104A1 (en) * 1995-01-20 1996-07-25 Elmer Eskil Treatment of cerebral ischemia and cerebral damage with neuroprotective agent

Also Published As

Publication number Publication date
AU9508198A (en) 2000-04-10
JP2002526453A (en) 2002-08-20
IL142120A0 (en) 2002-03-10
HK1040617A1 (en) 2002-06-21
AU766095B2 (en) 2003-10-09
AP2001002113A0 (en) 2001-06-30
BR9816047A (en) 2003-01-07
WO2000016794A1 (en) 2000-03-30
CN1322136A (en) 2001-11-14
EP1115412A1 (en) 2001-07-18
CA2345378A1 (en) 2000-03-30

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20010417

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RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61P 39/00 B

Ipc: 7A 61K 38/12 B

Ipc: 7A 61K 38/00 A

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20060619