EP1071327A4 - Fragments auto-antigenes, methodes et dosages - Google Patents
Fragments auto-antigenes, methodes et dosagesInfo
- Publication number
- EP1071327A4 EP1071327A4 EP99919952A EP99919952A EP1071327A4 EP 1071327 A4 EP1071327 A4 EP 1071327A4 EP 99919952 A EP99919952 A EP 99919952A EP 99919952 A EP99919952 A EP 99919952A EP 1071327 A4 EP1071327 A4 EP 1071327A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- assays
- methods
- autoantigenic fragments
- autoantigenic
- fragments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96436—Granzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Rheumatology (AREA)
- Pathology (AREA)
- Transplantation (AREA)
- Rehabilitation Therapy (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8264398P | 1998-04-22 | 1998-04-22 | |
US82643P | 1998-04-22 | ||
PCT/US1999/008774 WO1999053757A1 (fr) | 1998-04-22 | 1999-04-22 | Fragments auto-antigenes, methodes et dosages |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1071327A1 EP1071327A1 (fr) | 2001-01-31 |
EP1071327A4 true EP1071327A4 (fr) | 2004-09-29 |
Family
ID=22172472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99919952A Withdrawn EP1071327A4 (fr) | 1998-04-22 | 1999-04-22 | Fragments auto-antigenes, methodes et dosages |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1071327A4 (fr) |
JP (1) | JP2002511494A (fr) |
AU (1) | AU3755199A (fr) |
CA (1) | CA2329495A1 (fr) |
WO (1) | WO1999053757A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0126144D0 (en) * | 2001-10-31 | 2002-01-02 | Syngenta Ltd | Pesticidal formulations |
WO2004073739A1 (fr) * | 2003-02-21 | 2004-09-02 | Medvet Science Pty. Ltd. | Procede de diagnostic et de traitement |
CA2940579A1 (fr) | 2014-03-13 | 2015-09-17 | Universitaet Basel | Ligands glucidiques qui se lient aux anticorps igm contre la glycoproteine associee a la myeline |
AU2016323377B2 (en) | 2015-09-16 | 2021-04-15 | Universität Basel | Carbohydrate ligands that bind to antibodies against glycoepitopes of glycosphingolipids |
-
1999
- 1999-04-22 CA CA002329495A patent/CA2329495A1/fr not_active Abandoned
- 1999-04-22 EP EP99919952A patent/EP1071327A4/fr not_active Withdrawn
- 1999-04-22 WO PCT/US1999/008774 patent/WO1999053757A1/fr not_active Application Discontinuation
- 1999-04-22 AU AU37551/99A patent/AU3755199A/en not_active Abandoned
- 1999-04-22 JP JP2000544185A patent/JP2002511494A/ja not_active Withdrawn
Non-Patent Citations (4)
Title |
---|
ANDRADE F ET AL: "Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis.", IMMUNITY. APR 1998, vol. 8, no. 4, 1 April 1998 (1998-04-01), pages 451 - 460, XP002290799, ISSN: 1074-7613 * |
FROELICH CHRISTOPHER J ET AL: "Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 227, no. 3, 1996, pages 658 - 665, XP002290801, ISSN: 0006-291X * |
See also references of WO9953757A1 * |
SONG QIZHONG ET AL: "Interleukin-1-beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 184, no. 2, 1996, pages 619 - 626, XP002290800, ISSN: 0022-1007 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999053757A1 (fr) | 1999-10-28 |
AU3755199A (en) | 1999-11-08 |
CA2329495A1 (fr) | 1999-10-28 |
EP1071327A1 (fr) | 2001-01-31 |
JP2002511494A (ja) | 2002-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20001122 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
AX | Request for extension of the european patent |
Free format text: AL PAYMENT 20001122;LT PAYMENT 20001122;LV PAYMENT 20001122;MK PAYMENT 20001122;RO PAYMENT 20001122;SI PAYMENT 20001122 |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20040816 |
|
17Q | First examination report despatched |
Effective date: 20041004 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: MERCK FROSST CANADA LTD. Owner name: JOHNS HOPKINS UNIVERSITY Owner name: MERCK & CO., INC. (A NEW JERSEY CORP.) |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20061005 |