EP1061866A4 - Bone xenografts - Google Patents

Bone xenografts

Info

Publication number
EP1061866A4
EP1061866A4 EP99913897A EP99913897A EP1061866A4 EP 1061866 A4 EP1061866 A4 EP 1061866A4 EP 99913897 A EP99913897 A EP 99913897A EP 99913897 A EP99913897 A EP 99913897A EP 1061866 A4 EP1061866 A4 EP 1061866A4
Authority
EP
European Patent Office
Prior art keywords
bone xenografts
xenografts
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99913897A
Other languages
German (de)
French (fr)
Other versions
EP1061866A1 (en
Inventor
Kevin R Stone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crosscart Inc
Original Assignee
Crosscart Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crosscart Inc filed Critical Crosscart Inc
Publication of EP1061866A1 publication Critical patent/EP1061866A1/en
Publication of EP1061866A4 publication Critical patent/EP1061866A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A61L2/204—Formaldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A61L2/206—Ethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
EP99913897A 1998-03-16 1999-03-15 Bone xenografts Withdrawn EP1061866A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7813998P 1998-03-16 1998-03-16
US78139P 1998-03-16
US10075598P 1998-09-17 1998-09-17
US100755P 1998-09-17
PCT/US1999/005661 WO1999047080A1 (en) 1998-03-16 1999-03-15 Bone xenografts

Publications (2)

Publication Number Publication Date
EP1061866A1 EP1061866A1 (en) 2000-12-27
EP1061866A4 true EP1061866A4 (en) 2003-07-16

Family

ID=26760147

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99913897A Withdrawn EP1061866A4 (en) 1998-03-16 1999-03-15 Bone xenografts

Country Status (5)

Country Link
EP (1) EP1061866A4 (en)
JP (1) JP2002506677A (en)
AU (1) AU755316B2 (en)
CA (1) CA2323866A1 (en)
WO (1) WO1999047080A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6231608B1 (en) * 1995-06-07 2001-05-15 Crosscart, Inc. Aldehyde and glycosidase-treated soft and bone tissue xenografts
US6652818B1 (en) 1998-11-13 2003-11-25 Regeneration Technologies, Inc. Implant sterilization apparatus
US6482584B1 (en) 1998-11-13 2002-11-19 Regeneration Technologies, Inc. Cyclic implant perfusion cleaning and passivation process
US6613278B1 (en) 1998-11-13 2003-09-02 Regeneration Technologies, Inc. Tissue pooling process
US20030039678A1 (en) * 1998-03-16 2003-02-27 Stone Kevin R. Xenograft bone matrix for orthopedic applications
AU756366B2 (en) * 1998-04-02 2003-01-09 Crosscart, Inc. Bone xenografts
US20030068815A1 (en) * 1999-02-11 2003-04-10 Stone Kevin R. Sterilized xenograft tissue
JP4444918B2 (en) * 2003-05-15 2010-03-31 学校法人早稲田大学 Decellularization method and biological tissue processing apparatus
WO2005089411A2 (en) 2004-03-17 2005-09-29 Revivicor, Inc. Tissue products from animals lacking functional alpha 1,3 galactosyl transferase
US7648676B2 (en) 2004-04-20 2010-01-19 Rti Biologics, Inc. Process and apparatus for treating implants comprising soft tissue
DE102004036881A1 (en) * 2004-07-22 2006-02-16 Ossacur Ag Bioresorbable material for filling bone defects
DE102004036882A1 (en) * 2004-07-22 2006-02-16 Ossacur Ag Bioresorbable material for filling bone defects
US9061075B2 (en) 2005-12-14 2015-06-23 The Invention Science Fund I, Llc Bone delivery device
US8278094B2 (en) 2005-12-14 2012-10-02 The Invention Science Fund I, Llc Bone semi-permeable device
US8354258B2 (en) 2005-12-14 2013-01-15 The Invention Science Fund I, Llc Diatom device
US9005944B2 (en) 2005-12-14 2015-04-14 The Invention Science Fund I, Llc Bone cell delivery device
US8900865B2 (en) 2005-12-14 2014-12-02 The Invention Science Fund I, Llc Blood brain barrier device
US8367384B2 (en) 2005-12-14 2013-02-05 The Invention Science Fund I, Llc Bone semi-permeable device
US7855062B2 (en) 2005-12-14 2010-12-21 The Invention Science Fund I, Llc Bone cell delivery device
US20100191346A1 (en) * 2007-04-16 2010-07-29 Stephen Bloor Bone implant
US8551749B2 (en) 2009-04-23 2013-10-08 The Invention Science Fund I, Llc Device including bone cage and method for treatment of disease in a subject
AU2012355463C1 (en) 2011-12-20 2016-09-22 Lifecell Corporation Sheet tissue products
EP2793965B1 (en) 2011-12-20 2019-02-20 LifeCell Corporation Flowable tissue products
EP3461508A1 (en) 2012-01-24 2019-04-03 LifeCell Corporation Elongated tissue matrices
TR202009080A2 (en) * 2020-06-11 2021-12-21 Univ Yildiz Teknik Production of xenograft from animal bone.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2175507A (en) * 1985-05-29 1986-12-03 American Hospital Supply Corp Bone-grafting material
US5314476A (en) * 1992-02-04 1994-05-24 Osteotech, Inc. Demineralized bone particles and flowable osteogenic composition containing same
US5333626A (en) * 1991-12-31 1994-08-02 Cryolife, Inc. Preparation of bone for transplantation
WO1996012509A1 (en) * 1994-10-24 1996-05-02 Giuseppe Oliva Process for inactivating and eliminating the organic matrix from animal bone for heterotopic xenografts
WO1999044533A1 (en) * 1998-03-06 1999-09-10 Crosscart, Inc. Soft tissue xenografts

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4400833A (en) 1981-06-10 1983-08-30 Kurland Kenneth Z Means and method of implanting bioprosthetics
SE446372B (en) 1983-02-03 1986-09-08 Medinvent Sa BLOODKERL PROTES FOR USE AS SHUNT BETWEEN BLOODKERL
US4755593A (en) 1985-07-24 1988-07-05 Lauren Mark D Novel biomaterial of cross-linked peritoneal tissue
US4885585A (en) 1986-12-23 1989-12-05 Analog Devices, Inc. Ramp generator reset circuit
US5071741A (en) 1988-04-18 1991-12-10 Cryolife, Inc. Cryoprotective agent and its use in cryopreservation of cellular matter
US5171660A (en) 1989-04-26 1992-12-15 Cryolife, Inc. Process of revitalizing cells and tissue prior to cryopreservation
US5131850A (en) 1989-11-03 1992-07-21 Cryolife, Inc. Method for cryopreserving musculoskeletal tissues
US5192312A (en) * 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
US5160313A (en) 1991-05-14 1992-11-03 Cryolife, Inc. Process for preparing tissue for transplantation
US5411504A (en) * 1993-08-02 1995-05-02 Vilas; John W. Drill jig for animal prosthesis insertion
US5516532A (en) * 1994-08-05 1996-05-14 Children's Medical Center Corporation Injectable non-immunogenic cartilage and bone preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2175507A (en) * 1985-05-29 1986-12-03 American Hospital Supply Corp Bone-grafting material
US5333626A (en) * 1991-12-31 1994-08-02 Cryolife, Inc. Preparation of bone for transplantation
US5314476A (en) * 1992-02-04 1994-05-24 Osteotech, Inc. Demineralized bone particles and flowable osteogenic composition containing same
WO1996012509A1 (en) * 1994-10-24 1996-05-02 Giuseppe Oliva Process for inactivating and eliminating the organic matrix from animal bone for heterotopic xenografts
WO1999044533A1 (en) * 1998-03-06 1999-09-10 Crosscart, Inc. Soft tissue xenografts

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GALILI U ET AL: "HIGH-AFFINITY ANTI-GAL IMMUNOGLOBULIN G IN CHRONIC REJECTION OF XENOGRAFTS", XENOTRANSPLANTATION, MUNKSGAARD, DE, vol. 4, no. 3, August 1997 (1997-08-01), pages 127 - 131, XP009009159, ISSN: 0908-665X *
GALILI U ET AL: "PORCINE AND BOVINE CARTILAGE TRANSPLANTS IN CYNOMOLGUS MONKEY II. CHANGES IN ANTI-GAL RESPONSE DURING CHRONIC REJECTION", TRANSPLANTATION, WILLIAMS AND WILKINS, BALTIMORE, MD, US, vol. 63, no. 5, 15 March 1997 (1997-03-15), pages 646 - 651, XP009009157, ISSN: 0041-1337 *
See also references of WO9947080A1 *

Also Published As

Publication number Publication date
JP2002506677A (en) 2002-03-05
AU755316B2 (en) 2002-12-12
AU3186899A (en) 1999-10-11
WO1999047080A1 (en) 1999-09-23
EP1061866A1 (en) 2000-12-27
CA2323866A1 (en) 1999-09-23

Similar Documents

Publication Publication Date Title
EP1059891A4 (en) Soft tissue xenografts
EP1061866A4 (en) Bone xenografts
GB9807302D0 (en) Endoscope
AU141585S (en) Toothbrush
AU138441S (en) Toothbrush
EP1025776A4 (en) Toothbrush
AU136220S (en) Toothbrush
AU142196S (en) Tissue
GB2339924B (en) Endoscope
AU142195S (en) Tissue
GB9802248D0 (en) Toothbrush
AU140956S (en) Tissue
AU137971S (en) Implant
GB9812066D0 (en) Prosthesis construction
EP1140120A4 (en) Human brainiac-5
EP1077258A4 (en) Human hrpi
AU142197S (en) Tissue
GB2336524B (en) Toothbrush
GB9826207D0 (en) Bone conditions
GB9819875D0 (en) Prosthesis
EG21375A (en) Artificial musscles
SG74098A1 (en) Cartilage implant
CA82929S (en) Toothbrush
CA85138S (en) Toothbrush
CA83201S (en) Toothbrush

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20000925

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

A4 Supplementary search report drawn up and despatched

Effective date: 20030602

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61L 27/00 B

Ipc: 7A 61F 2/28 A

17Q First examination report despatched

Effective date: 20031202

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20040615