EP1059901B1 - Device for treatment of erectile dysfunction - Google Patents
Device for treatment of erectile dysfunction Download PDFInfo
- Publication number
- EP1059901B1 EP1059901B1 EP99909813A EP99909813A EP1059901B1 EP 1059901 B1 EP1059901 B1 EP 1059901B1 EP 99909813 A EP99909813 A EP 99909813A EP 99909813 A EP99909813 A EP 99909813A EP 1059901 B1 EP1059901 B1 EP 1059901B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- vessel
- pumping
- suction chamber
- vacuum chamber
- vacuum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/41—Devices for promoting penis erection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
- A61F5/41—Devices for promoting penis erection
- A61F2005/412—Devices for promoting penis erection by vacuum means
Definitions
- This invention relates to a device for the treatment of erectile dysfunction or for penile exercise in the human male.
- a device (10,100) for the treatment of erectile dysfunction or for penile exercise comprising: a vessel (12) having an outer surface which is substantially cylindrical for at least part of its length, the vessel (12) defining a vacuum chamber, and having a mouth opening (12,4) leading into the vacuum chamber (14), the vacuum chamber (14) being shaped and dimensioned to accommodate a human penis in an erect state; and pumping means (50); characterised in that the pumping means comprises an annular pumping member (16) mounted on and extending concentrically around the cylindrical portion of the outer surface of the vessel (12) intermediate the ends thereof so that an annular suction chamber (20) is defined between the outer surface of the vessel (12) and the pumping member (16), the pumping member (16) and vessel (12) being slidingly displaceable relative to one another which relative displacement changes the volume of the suction chamber (20); at least one pumping passage (28) extending from the vacuum chamber (14), at a position intermediate the ends thereof, to the suction chamber (20);
- the device may include a seal means positioned in the vicinity of the mouth opening and configured sealingly to engage with an outer surface of a human penis inserted in the vacuum chamber.
- the pumping means By arranging the pumping means such that the volume of the pumping chamber increases when the pumping member is displaced towards the mouth of the vessel the primary loads applied to the device, in use, are towards a user's body which helps to minimize any discomfort the user may experience.
- the pumping vessel may have a cylindrical wall and the or each pumping passage may extend through the wall and have a mouth opening into the suction chamber, the first one way valve means being in the form of at least one elastically deformable band extending around the cylindrical wall to cover the or each mouth.
- the second one way valve means may include an O-ring configured to provide an air tight seal between the pumping member and the vessel when being displaced relative to one another to increase the volume of the pumping chamber and to permit air to be discharged through the at least one exhaust passage when the pumping member and the vessel are being displaced relative to one another to decrease the volume of the pumping chamber.
- the pressure in the vacuum chamber not decrease below a predetermined minimum pressure, typically of the order of -0.57 bar.
- a predetermined minimum pressure typically of the order of -0.57 bar.
- the device may include vacuum restriction means for restricting the vacuum which can be drawn in the vacuum chamber.
- the vacuum restriction means may include a stroke limiting member positioned in the suction chamber to restrict the stroke through which the pumping member is displaceable relative to the vessel.
- the seal means may include a sealing constriction ring which is readily dismountably mounted on the vessel in the vicinity of the mouth opening, the constriction ring including a generally ring-shaped body having a circumferentially extending engagement formation for releasable sealing engagement with the vessel in the vicinity of the mouth opening and a constriction ring opening configured sealingly to abut against the outer surface of a human penis.
- the body of the constriction ring may be formed of a unitary moulding of an elastomeric material.
- the elastomeric material may be a silicone rubber and have a hardness of 50 A Shore.
- the size of the constriction ring opening will depend on the intended application. Hence, where intended for use in the treatment of erectile dysfunction the opening will be sufficiently small to inhibit blood flow from the penis once an erection is attained in order to maintain the erection. In contrast, when the device is intended to be used for penile exercise the opening will be sufficiently small to seal against a surface of the penis and sufficiently large to permit blood to drain from the erect penis.
- the constriction ring opening may have a diameter of between 13 and 24 mm.
- the device may include a plurality of interchangeable sealing constriction rings each having a constriction ring opening of a different size.
- reference numeral 10 generally indicates a device in accordance with the invention for use in the treatment of erectile dysfunction or for penile exercise.
- the device 10 includes a hollow generally cigar shaped vessel 12 defining an elongate primary or vacuum chamber 14 ( Figure 3).
- the device 10 further includes pumping means, generally indicated by reference numeral 50 for pumping air out of the vacuum chamber 14.
- the vessel 12 has a generally cylindrical wall 13.
- the pumping means 50 includes a cylindrical pumping member or sleeve 16 which is mounted on and slidingly displaceable relative to the vessel 12 in the directions of the arrows 18, 22 ( Figures 2 and 3). Referring, in particular, to Figure 3 the vessel 12 and the sleeve 16 are configured so that, together, they form an annular secondary or suction chamber 20. As is also evident from Figure 3, displacement of the pumping member in the direction of the arrow 22 will increase the volume of the suction chamber 20 and displacement in the direction of the arrow 18 will decrease the volume of the suction chamber 20.
- the pumping means 50 further includes sealing means in the form of a pair of O-rings 24, 26, described in further detail below, and pumping passages 28 in the wall 13 of the vessel 12 which provide a flow path for air to flow from the vacuum chamber 14 to the suction chamber 20.
- Four pumping passages 28 are provided, arranged in diametrically opposed pairs.
- the pumping means 50 includes upper exhaust passages, described in further detail below, indicated by the dotted lines 29 in Figure 3 which allow air in the suction chamber 20 to be discharged to atmosphere when the pumping member 16 is moved in the direction of the arrow 18.
- the pumping means 50 further includes one way valve means in the form of a flat rubber band 32, described in further detail below, extending around the cylindrical vessel 12 to cover the pumping passages 28.
- the vessel 12 has an open bottom end or mouth opening 12.4 (Figure 2) which leads into an end of the vacuum chamber 14. Seal means in the form of a sealing constriction ring 34 is mounted on the vessel 12 in the vicinity of the mouth opening 12.4, as described in further detail below.
- the cylindrical vessel 12 has a closed dome-shaped upper end 12.1 and a lower shoulder 12.2 adjacent the opening 12.4 with a narrower cylindrical part 12.3 extending from it and defining the opening 12.4.
- the sleeve 16 comprises a top part 16.1 and a bottom part 16.2 which are screw-threadedly joined by complementary screw threads generally indicated by reference numeral 16.3 with a lower portion of the upper part 16.1 overlapping an upper portion of the lower part 16.2 at the screw threads 16.3.
- the upper part 16.1 has an upper inwardly directed collar 16.4 with a tapered upper face 16.5.
- the lower part 16.2 has a complementary tapered lower face 16.6.
- the lower part 16.2 has a circumferentially extending inwardly directed recess 16.7 and the O-ring 26 is positioned in the recess 16.7.
- the O-ring 26 is configured so that it sealingly and slidingly abuts the wall 13 of the cylindrical vessel 12 to provide an airtight seal between the vessel 12 and the pumping member or sleeve 16.
- a collar 12.7 projects outwardly from the wall 13 below the inwardly directed collar 16.4 of the sleeve 16.
- the exhaust passages 29 are formed by spaced recesses in the collar 12.7.
- a second outwardly projecting collar 12.8 is located below the collar 12.7 and the wall 13 of the vessel 12 between the collars 12.7 and 12.8 is recessed.
- the collar 12.7 projects slightly further from the wall 13 of the vessel 12 than does the collar 12.8 as can be seen, in particular, in Figure 3. This allows the sleeve 16 to slide smoothly over the collar 12.7 which thus acts as a guide for accurate "centering" of the sleeve 16.
- the collars 12.7, 12.8 define between them an annular cavity 16.8 and the O-ring 24 is positioned in the cavity 12.8.
- the O-ring 24 has a diameter which is selected so that it abuts slidingly and sealingly against the inside face of the sleeve 16.
- a further recessed portion 38 in the wall 13 of the vessel 12 is provided below the collar 12.8 and the pumping passages 28 extend through the wall 13 of the vessel 12 in the recessed portion 38.
- the rubber band 32 is located in the recessed portion 38 and covers the pumping passages 28.
- a vacuum relief hole 17 is provided in the top part 16.1 of the sleeve 16 adjacent the upper O-ring 24 to release vacuum when the sleeve 16 is in its lowest position.
- a circumferentially extending rubber stop member 23 is provided above the collar 12.7 to dampen the sound of the sleeve when it is reciprocated.
- the O-ring 24 is displaced upwardly so that it abuts against the collar 12.7 and is clear of the collar 12.8.
- the volume of the exhaust chamber 20 is reduced and air in the exhaust chamber is driven past the O-ring 24 and the collar 12.8 and out through the exhaust passages 29.
- the O-ring 24 is displaced downwardly and abuts sealingly against the collar 12.8 thereby forming an airtight seal between the sleeve 16 and the vessel 12.
- the volume of the exhaust chamber 20 is increased so that air is sucked via the pumping passages 28, under and past the rubber band 32, which acts as a one way valve by allowing air flow from the vacuum chamber 14 to the suction chamber 20 but preventing air flow in the opposite direction.
- air is again exhausted via the exhaust openings 29.
- the O-ring 24 hence functions as a one way valve. In this way by reciprocating movement of the sleeve 16, air is drawn out of the vacuum chamber 14 thereby, when the mouth is closed, incrementally reducing the pressure in the vacuum chamber 14. It will be appreciated that if desired the O-ring 26 can function as a one way valve in addition to the O-ring 24.
- the constriction ring 34 comprises a body of rubber, e.g. silicone rubber.
- the ring 34 includes a central opening 34.1 surrounded by a tubular central portion or collar 34.2, a circumferentially extending upwardly directed ring-shaped formation or skirt 34.3 and a flat annular connecting web or recessed portion 34.4 between the collar 34.2 and the ring-shaped formation 34.3.
- the ring-shaped formation has an inner surface or wall 34.5.
- the outside diameter of the constriction ring 34 is about 58 mm.
- the diameter of the wall 34.5 is about 47 mm.
- the opening 34.1 has a diameter of 13 to 24 mm.
- the flaccid penis of a user (not shown) is drawn into the vessel 12 of the device 10 through the opening 34.1 of the constriction ring 34 by operating the sleeve 16 to reduce the air pressure in the pumping chamber 14 the penis is drawn into the vessel 12 and by virtue of the reduced pressure in the vacuum chamber 14 blood is drawn into the penis to achieve an erection of the penis in the vacuum chamber 14.
- the constriction ring 34 seats sealingly around the penis.
- the pumping action causes a pressure drop in the vacuum chamber 14 to about -0.4 bar. This is sufficient to draw the penis into the vessel 12 and to draw blood into the penis to cause an erection.
- the skirt 34.2 is deformed by the drawing of the penis into the opening 34.1 thereby causing the seal-penis contact area to be increased by the draping of the skirt 34.2 onto the penis, collar-fashion.
- the vessel 12 is simply disengaged from the constriction ring 34 which remains in place on the erect penis.
- the diameter of the opening 34.1 is selected by a user of the device 10 so that blood flow from the penis is constricted.
- the diameter of the opening 34.1 is selected by a user so that the constriction ring engages sealingly with the penis during the pumping action so that an erection is achieved but not so that blood flow from the penis is constricted when the vacuum is relieved.
- blood flow from the penis relaxes the erection.
- the vessel 12 is provided with a removable vacuum gauge for measuring the vacuum inside the vessel 12. Once a user is familiar with the use of the device, the vacuum gauge may be removed.
- reference numeral 100 refers generally to another device in accordance with the invention for use in the treatment of erectile dysfunction or for penile exercise. Unless otherwise indicated, the same reference numerals used above are used to designate similar parts.
- the vessel 12 is formed in two parts 102 and 104 which are screw-threadedly connected together.
- the part 102 defines an annular shoulder 106, the O-ring 24 being held captive between the shoulder 106 and the collar 12.7.
- a seal 108 is provided between the two parts 102, 104.
- the shoulder 106 functions in the same manner as the collar 12.8 of Figures 1 to 3 such that the O-ring 24 cooperates with the shoulder 106 to form a non-return or one way valve means.
- the O-ring 26 is held captive between the lower part 16.2 and an annular insert 110 which is sandwiched between the upper part 16.1 and the lower part 16.2 when they are screwed together. If desired, the lower part 16.2 and insert 110 can be configured such that the O-ring 26 also functions as a non-return valve.
- the device 100 includes vacuum restriction means, generally indicated by reference numeral 112 for restricting the vacuum which can be drawn in the vacuum chamber 14.
- vacuum restriction means 112 for restricting the vacuum which can be drawn in the vacuum chamber 14. It will be appreciated that, in use, air will be drawn from the vacuum chamber 14 into the suction chamber 20 only when the pressure in the suction chamber 24 is below that in the vacuum chamber 14. Accordingly, by limiting the maximum vacuum which can be drawn in the suction chamber 20 the maximum vacuum which can be drawn in the vacuum chamber 14 is also limited.
- the vacuum restriction means 112 includes a stoke limiting member 114 which is positioned in the suction chamber 20 and is designed to limit the maximum stroke of the pumping member or sleeve 16 relative to the vessel 12. It is hence a relatively simple matter to calculate the stroke volume of the sleeve 16 and hence the maximum vacuum which can be drawn.
- a further difference between the device 100 and the device 10 is that, in the case of the device 100 the pumping member or sleeve 16 is moved closer towards the mouth 12.4 and is arranged that at the extremities of its stroke it does not protrude beyond the ends of the vessel 12. This reduces the risk that an article of clothing or a body part may be caught between the sleeve 16 and the vessel 12.
- the diameter of the outer surface of the sleeve 16 increases towards the mouth 12.4.
- the maximum effort applied to the sleeve 16 is when it is being displaced in the direction of arrow 22. Accordingly this gentle taper of the sleeve 16 reduces the risk that a user's hand will slip on the sleeve 16.
- a further difference between the device 100 and the device 10 is that, in the case of the device 100, the sealing constriction ring 34 is provided with a pair of annular ribs or gripping formations 34.6 which assist in removing the ring 34 on the vessel 12.
- the device 100 will be used in substantially the identical fashion to the device 10.
- the Applicant believes that it is an advantage of the invention as illustrated that the device due to its size, form and simplicity of use can be easily used in an intimate situation. It is a particular advantage that the pumping vessel is easily detached from the constriction ring leaving the constriction ring in place.
- the sealing ring may be removably attached to the device to form a unit for ease of use.
Landscapes
- Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Nursing (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- External Artificial Organs (AREA)
- Load-Engaging Elements For Cranes (AREA)
Abstract
Description
Claims (11)
- A device (10,100) for the treatment of erectile dysfunction or for penile exercise, the device comprising:a vessel (12) having an outer surface which is substantially cylindrical for at least part of its length, the vessel (12) defining a vacuum chamber, and having a mouth opening (12,4) leading into the vacuum chamber (14), the vacuum chamber (14) being shaped and dimensioned to accommodate a human penis in an erect state; andpumping means (50); characterised in that the pumping means comprisesan annular pumping member (16) mounted on and extending concentrically around the cylindrical portion of the outer surface of the vessel (12) intermediate the ends thereof so that an annular suction chamber (20) is defined between the outer surface of the vessel (12) and the pumping member (16), the pumping member (16) and vessel (12) being slidingly displaceable relative to one another which relative displacement changes the volume of the suction chamber (20);at least one pumping passage (28) extending from the vacuum chamber (14), at a position intermediate the ends thereof, to the suction chamber (20);at least one exhaust passage (29) extending from the suction chamber (20);first one way valve means (32) which permits fluid flow from the vacuum chamber (14) to the suction chamber (20) via the, or each, pumping passage (28); andsecond one way valve mens which permits fluid to be discharged from the suction chamber (20) via the or each exhaust passage (29) to atmosphere.
- A device (10,100) according to claim 1, wherein the or each pumping passage (28) is positioned and the pumping member (16) is arranged so that displacement of the pumping member (16) towards the mouth (12,4) of the vessel (12) increases the volume of the suction chamber (20) and causes air to flow from the vacuum chamber (14) through the or each pumping passage (28) into the suction chamber (20) and displacement of the pumping member (16) away from the mouth (12,4) of the vessel (12) decreases the volume of the suction chamber (20) and causes air to be discharged from the suction chamber (20) through the exhaust passage (29) to atmosphere.
- A device according to claim 1 or claim 2, wherein the vessel (12) has a cylindrical wall (13) and the or each pumping passage (28) extends through the wall (13) and has a mouth opening into the suction chamber (20), the first one way valve means being in the form of at least one elastically deformable band (32) extending around the cylindrical wall (13) to cover the or each mouth.
- A device according to any of the preceding claims, wherein the second one way valve means includes an O-ring (24) configured to provide an air tight seal between the pumping member (16) and the vessel (12) when being displaced relative to one another to increase the volume of the suction chamber (20) and to permit air to be discharged through the at least one exhaust passage (29) when the pumping member (16) and the vessel (12) are being displaced relative to one another to decrease the volume of the suction chamber (20).
- A device according to any of the preceding claims, wherein it includes vacuum restriction means (112) for restricting the vacuum which can be drawn in the vacuum chamber (14).
- A device according to claim 5, wherein the vacuum restriction means includes a stroke limiting member (114) positioned in the suction chamber (20) to restrict the stroke through which the pumping member 16) is displaceable relative to the vessel (12).
- A device according to any of the preceding claims, wherein at the extremities of its stroke, the pumping member (16) does not protrude beyond the ends of the vessel (12).
- A device according to any of the preceding claims, wherein it includes seal means positioned in the vicinity of the mouth opening (12,4) and configured sealingly to engage with an outer surface of a human penis inserted into the vacuum chamber (14).
- A device according to claim 8, wherein the seal means includes a sealing constriction ring (34) which is dismountably mounted on the vessel (12) in the vicinity of the mouth opening (12,4), the constriction ring (34) including a generally ring-shaped body having a circumferentially extending engagement formation (34.3) for releasable sealing engagement with a vessel (12) in the vicinity of the mouth opening (12,4) and a constriction ring opening (34.1) configured sealingly to abut against the outer surface of a human penis.
- A device according to claim 9, wherein the body is formed of a unitary moulding of an elastomeric material.
- A device according to claim 9 or claim 10, wherein the constriction ring opening (34,1) has a diameter of between 12 and 24 mm.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ZA9801789 | 1998-03-03 | ||
ZA981789 | 1998-03-03 | ||
PCT/US1999/004736 WO1999044550A1 (en) | 1998-03-03 | 1999-03-03 | Device for treatment of erectile dysfunction |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1059901A1 EP1059901A1 (en) | 2000-12-20 |
EP1059901A4 EP1059901A4 (en) | 2001-07-04 |
EP1059901B1 true EP1059901B1 (en) | 2004-07-21 |
Family
ID=25586885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99909813A Expired - Lifetime EP1059901B1 (en) | 1998-03-03 | 1999-03-03 | Device for treatment of erectile dysfunction |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1059901B1 (en) |
JP (1) | JP2002505154A (en) |
CN (1) | CN1291874A (en) |
AT (1) | ATE271363T1 (en) |
AU (1) | AU2893699A (en) |
DE (1) | DE69918809T2 (en) |
WO (1) | WO1999044550A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6705987B2 (en) | 2002-04-17 | 2004-03-16 | Endocare, Inc. | Penile seal and constriction ring |
GB2417686B (en) * | 2004-09-03 | 2009-08-12 | John Oakes | Pump for assisting penis erection adapted for use underwater |
GB0922259D0 (en) * | 2009-12-21 | 2010-02-03 | Oakes John | Constriction ring |
KR101677355B1 (en) * | 2011-09-08 | 2016-11-17 | 로널드 앨런 브라운 | Apparatus and method for facilitating male orgasm |
US11432929B2 (en) | 2015-12-31 | 2022-09-06 | Menova International, Inc. | Prosthesis for improved penis function |
US9504573B1 (en) * | 2015-12-31 | 2016-11-29 | James J. Elist | Prosthesis for improved penis function |
JP7358399B2 (en) * | 2018-05-22 | 2023-10-10 | バーネット-ジョーンズ,ロドニー | stimulation therapy device |
CN109549834B (en) * | 2019-01-14 | 2023-12-19 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | Soaking device for soaking affected parts of human or animals |
CN215535475U (en) * | 2021-01-15 | 2022-01-18 | 深圳光点科技有限公司 | Erection aid for male |
KR200496586Y1 (en) | 2021-03-19 | 2023-03-08 | 이동희 | Medical manual type vacuum pressure generator |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH347300A (en) * | 1957-02-22 | 1960-06-30 | Meldi Giuseppe | Device to combat impotence |
US4753227A (en) * | 1987-06-22 | 1988-06-28 | Yanuck Jr Rudolph R | Erection device and method |
US5095895A (en) * | 1990-05-11 | 1992-03-17 | Dacomed Corporation | Negative pressure erection apparatus |
DE4344686C2 (en) * | 1993-12-27 | 1996-10-31 | Temple Cornell De | Erection aid |
US5624378A (en) * | 1994-08-31 | 1997-04-29 | Osbon Medical Systems, Inc. | Pumpless vacuum generation for augmenting male potency |
WO1997025007A1 (en) * | 1996-01-11 | 1997-07-17 | Vollrath Andrew J | Non-invasive penile erection device |
US5782621A (en) * | 1996-04-22 | 1998-07-21 | Mission Pharmacal Company | Manual pump with inherent vacuum limit |
US5836864A (en) * | 1996-08-07 | 1998-11-17 | Clark, Jr.; Roland T. | Penile lengthening traction device |
-
1999
- 1999-03-03 DE DE69918809T patent/DE69918809T2/en not_active Expired - Lifetime
- 1999-03-03 EP EP99909813A patent/EP1059901B1/en not_active Expired - Lifetime
- 1999-03-03 AT AT99909813T patent/ATE271363T1/en not_active IP Right Cessation
- 1999-03-03 CN CN99803562A patent/CN1291874A/en active Pending
- 1999-03-03 WO PCT/US1999/004736 patent/WO1999044550A1/en active IP Right Grant
- 1999-03-03 JP JP2000534157A patent/JP2002505154A/en active Pending
- 1999-03-03 AU AU28936/99A patent/AU2893699A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1999044550A1 (en) | 1999-09-10 |
DE69918809D1 (en) | 2004-08-26 |
CN1291874A (en) | 2001-04-18 |
DE69918809T2 (en) | 2005-07-21 |
EP1059901A4 (en) | 2001-07-04 |
AU2893699A (en) | 1999-09-20 |
EP1059901A1 (en) | 2000-12-20 |
JP2002505154A (en) | 2002-02-19 |
ATE271363T1 (en) | 2004-08-15 |
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