EP1012334A4 - Compositions et procedes permettant de determiner la sensibilite et la resistance vis-a-vis de medicaments antiviraux, et criblage de medicaments antiviraux - Google Patents
Compositions et procedes permettant de determiner la sensibilite et la resistance vis-a-vis de medicaments antiviraux, et criblage de medicaments antivirauxInfo
- Publication number
- EP1012334A4 EP1012334A4 EP98940779A EP98940779A EP1012334A4 EP 1012334 A4 EP1012334 A4 EP 1012334A4 EP 98940779 A EP98940779 A EP 98940779A EP 98940779 A EP98940779 A EP 98940779A EP 1012334 A4 EP1012334 A4 EP 1012334A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- viral drug
- compositions
- resistance
- methods
- determining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
- C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90350797A | 1997-07-30 | 1997-07-30 | |
US903507 | 1997-07-30 | ||
PCT/US1998/015967 WO1999006597A1 (fr) | 1997-07-30 | 1998-07-30 | Compositions et procedes permettant de determiner la sensibilite et la resistance vis-a-vis de medicaments antiviraux, et criblage de medicaments antiviraux |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1012334A1 EP1012334A1 (fr) | 2000-06-28 |
EP1012334A4 true EP1012334A4 (fr) | 2004-12-29 |
Family
ID=25417619
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP98940779A Withdrawn EP1012334A4 (fr) | 1997-07-30 | 1998-07-30 | Compositions et procedes permettant de determiner la sensibilite et la resistance vis-a-vis de medicaments antiviraux, et criblage de medicaments antiviraux |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1012334A4 (fr) |
JP (1) | JP2001512036A (fr) |
KR (1) | KR20010022420A (fr) |
AU (1) | AU8897698A (fr) |
CA (1) | CA2298102A1 (fr) |
WO (1) | WO1999006597A1 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6242187B1 (en) | 1996-01-29 | 2001-06-05 | Virologic, Inc. | Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening |
KR100537153B1 (ko) * | 1996-01-29 | 2006-12-15 | 바이럴러직, 인코퍼레이티드 | 항바이러스약품감수성및내성그리고항바이러스약물의스크리닝을결정하는방법및조성물 |
US20030028011A1 (en) * | 1997-07-30 | 2003-02-06 | Parkin Neil T. | Compositions and methods for determining susceptibility of hepatitis C virus to anti-viral drugs |
WO2001007646A2 (fr) * | 1999-07-21 | 2001-02-01 | Martin Heinkelein | Procede de quantification de l'effet antiviral de principes actifs antiviraux |
DE60140211D1 (de) * | 2000-06-08 | 2009-11-26 | Virco Bvba | Verfahren um die resistenz gegen ein therapeutisches agenz vorherzusagen unter verwendung neuronaler netze |
AU2003218111B8 (en) * | 2002-03-11 | 2008-11-20 | Lab 21 Limited | Methods and compositions for identifying and characterizing hepatitis C |
EP1454988A1 (fr) * | 2003-03-03 | 2004-09-08 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Pseudo-particules du flavivirus infectieuses contenant des protéines prM-E d'enveloppe |
EP2527474A1 (fr) | 2006-10-20 | 2012-11-28 | Innogenetics N.V. | Méthodologie d'analyse des variations de séquence dans la zone génomique HCV NS3/4A |
US20090325145A1 (en) | 2006-10-20 | 2009-12-31 | Erwin Sablon | Methodology for analysis of sequence variations within the hcv ns5b genomic region |
CN104039984A (zh) * | 2011-12-02 | 2014-09-10 | 美国控股实验室公司 | 用于hcv抑制剂抗性亚群表型检测的方法 |
CN113299340B (zh) * | 2021-06-09 | 2023-06-30 | 四川大学华西医院 | 靶标试验药物的筛选方法、靶标试验药物筛选器 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0291893A1 (fr) * | 1987-05-19 | 1988-11-23 | The Du Pont Merck Pharmaceutical Company | Lignes de cellules humaines stables exprimant un produit de gène indicateur sous des contrôles génétiques specifiques à un virus |
WO1994008002A2 (fr) * | 1992-09-28 | 1994-04-14 | Chiron Corporation | Procedes et compositions de regulation de la translation de proteines hcv |
WO1995022622A1 (fr) * | 1994-02-18 | 1995-08-24 | University Of Washington | Procedes et compositions de criblage de medicaments anti-sida |
WO1997027480A1 (fr) * | 1996-01-26 | 1997-07-31 | Virco N.V. | Procede pour gerer la chimiotherapie de patients seropositifs vih sur la base de la sensibilite medicamenteuse phenotypique de souches humaines du vih |
WO1997027319A1 (fr) * | 1996-01-29 | 1997-07-31 | Virologic, Inc. | Compositions et procedes pour determiner la sensibilite et la resistance vis-a-vis de medicaments antiviraux et criblage de medicaments antiviraux |
-
1998
- 1998-07-30 EP EP98940779A patent/EP1012334A4/fr not_active Withdrawn
- 1998-07-30 AU AU88976/98A patent/AU8897698A/en not_active Abandoned
- 1998-07-30 JP JP2000505336A patent/JP2001512036A/ja not_active Withdrawn
- 1998-07-30 WO PCT/US1998/015967 patent/WO1999006597A1/fr not_active Application Discontinuation
- 1998-07-30 KR KR1020007001002A patent/KR20010022420A/ko not_active Application Discontinuation
- 1998-07-30 CA CA002298102A patent/CA2298102A1/fr not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0291893A1 (fr) * | 1987-05-19 | 1988-11-23 | The Du Pont Merck Pharmaceutical Company | Lignes de cellules humaines stables exprimant un produit de gène indicateur sous des contrôles génétiques specifiques à un virus |
WO1994008002A2 (fr) * | 1992-09-28 | 1994-04-14 | Chiron Corporation | Procedes et compositions de regulation de la translation de proteines hcv |
WO1995022622A1 (fr) * | 1994-02-18 | 1995-08-24 | University Of Washington | Procedes et compositions de criblage de medicaments anti-sida |
WO1997027480A1 (fr) * | 1996-01-26 | 1997-07-31 | Virco N.V. | Procede pour gerer la chimiotherapie de patients seropositifs vih sur la base de la sensibilite medicamenteuse phenotypique de souches humaines du vih |
WO1997027319A1 (fr) * | 1996-01-29 | 1997-07-31 | Virologic, Inc. | Compositions et procedes pour determiner la sensibilite et la resistance vis-a-vis de medicaments antiviraux et criblage de medicaments antiviraux |
Non-Patent Citations (4)
Title |
---|
ENOMOTO N ET AL: "Hepatitis C virus quasispecies populations during chronic hepatitis C infection", TRENDS IN MICROBIOLOGY 1995 UNITED KINGDOM, vol. 3, no. 11, 1995, pages 445 - 447, XP002284841, ISSN: 0966-842X * |
HAHM BUMSUK ET AL: "Generation of a novel poliovirus with a requirement of hepatitis C virus protease NS3 activity", VIROLOGY, vol. 226, no. 2, 1996, pages 318 - 326, XP002284878, ISSN: 0042-6822 * |
See also references of WO9906597A1 * |
STRAIR R K ET AL: "RECOMBINANT RETROVIRAL SYSTEMS FOR THE ANALYSIS OF DRUG RESISTANT HIV", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 21, no. 20, 1993, pages 4836 - 4842, XP002924448, ISSN: 0305-1048 * |
Also Published As
Publication number | Publication date |
---|---|
KR20010022420A (ko) | 2001-03-15 |
CA2298102A1 (fr) | 1999-02-11 |
AU8897698A (en) | 1999-02-22 |
EP1012334A1 (fr) | 2000-06-28 |
WO1999006597A1 (fr) | 1999-02-11 |
JP2001512036A (ja) | 2001-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20000228 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: PARKIN, NEIL, T. Inventor name: WHITCOMB, JEANNETTE, M. Inventor name: CAPON, DANIEL, J. |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20041111 |
|
17Q | First examination report despatched |
Effective date: 20050622 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: MONOGRAM BIOSCIENCES, INC. |
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17Q | First examination report despatched |
Effective date: 20050622 |
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REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1025362 Country of ref document: HK |
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18D | Application deemed to be withdrawn |
Effective date: 20090324 |