EP1012155A4 - Human uncoupling protein 3 - Google Patents

Human uncoupling protein 3

Info

Publication number
EP1012155A4
EP1012155A4 EP19980923517 EP98923517A EP1012155A4 EP 1012155 A4 EP1012155 A4 EP 1012155A4 EP 19980923517 EP19980923517 EP 19980923517 EP 98923517 A EP98923517 A EP 98923517A EP 1012155 A4 EP1012155 A4 EP 1012155A4
Authority
EP
European Patent Office
Prior art keywords
uncoupling protein
human uncoupling
human
protein
uncoupling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19980923517
Other languages
German (de)
French (fr)
Other versions
EP1012155A1 (en
Inventor
Qingyun Liu
Fang Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9716886.8A external-priority patent/GB9716886D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1012155A1 publication Critical patent/EP1012155A1/en
Publication of EP1012155A4 publication Critical patent/EP1012155A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
EP19980923517 1997-05-20 1998-05-19 Human uncoupling protein 3 Withdrawn EP1012155A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US4717997P 1997-05-20 1997-05-20
GB9716886 1997-08-08
GBGB9716886.8A GB9716886D0 (en) 1997-08-08 1997-08-08 Human uncoupling protein 3
US6914197P 1997-12-09 1997-12-09
US69141P 1997-12-09
PCT/US1998/010215 WO1998052958A1 (en) 1997-05-20 1998-05-19 Human uncoupling protein 3
US47179P 2008-04-23

Publications (2)

Publication Number Publication Date
EP1012155A1 EP1012155A1 (en) 2000-06-28
EP1012155A4 true EP1012155A4 (en) 2002-11-04

Family

ID=27268968

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19980923517 Withdrawn EP1012155A4 (en) 1997-05-20 1998-05-19 Human uncoupling protein 3

Country Status (4)

Country Link
EP (1) EP1012155A4 (en)
JP (1) JP2002502240A (en)
CA (1) CA2289945A1 (en)
WO (1) WO1998052958A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2288901A1 (en) 1997-05-07 1998-11-12 Novartis Ag Uncoupling protein homologue: ucp 3
AU6041399A (en) 1998-09-22 2000-04-10 Genentech Inc. Ucp4
ATE492640T1 (en) 1998-11-30 2011-01-15 Genentech Inc RELEASING PROTEIN 5 - UCP5
US7342102B2 (en) 1998-11-30 2008-03-11 Genentech, Inc. Uncoupling protein 5 (UCP5)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039432A1 (en) * 1997-03-05 1998-09-11 Smithkline Beecham Plc Polynucleotides and polypeptides belonging to the uncoupling proteins family
WO1998050542A1 (en) * 1997-05-07 1998-11-12 Novartis Ag Uncoupling protein homologue: ucp 3

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039432A1 (en) * 1997-03-05 1998-09-11 Smithkline Beecham Plc Polynucleotides and polypeptides belonging to the uncoupling proteins family
WO1998050542A1 (en) * 1997-05-07 1998-11-12 Novartis Ag Uncoupling protein homologue: ucp 3

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BOSS O ET AL: "UNCOUPLING PROTEIN-3: A NEW MEMBER OF THE MITOCHONDRIAL CARRIER FAMILY WITH TISSUE-SPECIFIC EXPRESSION", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 408, no. 1, 1997, pages 39 - 42, XP002067895, ISSN: 0014-5793 *
DATABASE SWALLPROT [online] XP002214359, Database accession no. p55916 *
DATABASE SWALLPROT [online] XP002214361, Database accession no. p56501 *
MATSUDA J ET AL: "Cloning of rat uncoupling protein-3 and uncoupling protein-2 cDNAs: their gene expression in rats fed high-fat diet", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 418, no. 1-2, 24 November 1997 (1997-11-24), pages 200 - 204, XP004261541, ISSN: 0014-5793 *
See also references of WO9852958A1 *
YOSHITOMI H ET AL: "Cloning of mouse uncoupling protein 3 cDNA and 5'-flanking region, and its genetic map", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 215, no. 1, July 1998 (1998-07-01), pages 77 - 84, XP004149231, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
JP2002502240A (en) 2002-01-22
CA2289945A1 (en) 1998-11-26
EP1012155A1 (en) 2000-06-28
WO1998052958A1 (en) 1998-11-26

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