EP0948330A4 - Antagonistes du recepteur d'il-8 - Google Patents

Antagonistes du recepteur d'il-8

Info

Publication number
EP0948330A4
EP0948330A4 EP97937142A EP97937142A EP0948330A4 EP 0948330 A4 EP0948330 A4 EP 0948330A4 EP 97937142 A EP97937142 A EP 97937142A EP 97937142 A EP97937142 A EP 97937142A EP 0948330 A4 EP0948330 A4 EP 0948330A4
Authority
EP
European Patent Office
Prior art keywords
receptor antagonists
antagonists
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97937142A
Other languages
German (de)
English (en)
Other versions
EP0948330A1 (fr
Inventor
Katherine L Widdowson
John Gerald Gleason
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0948330A1 publication Critical patent/EP0948330A1/fr
Publication of EP0948330A4 publication Critical patent/EP0948330A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
EP97937142A 1996-08-06 1997-08-06 Antagonistes du recepteur d'il-8 Withdrawn EP0948330A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2380296P 1996-08-06 1996-08-06
US23802P 1996-08-06
PCT/US1997/013858 WO1998005328A1 (fr) 1996-08-06 1997-08-06 Antagonistes du recepteur d'il-8

Publications (2)

Publication Number Publication Date
EP0948330A1 EP0948330A1 (fr) 1999-10-13
EP0948330A4 true EP0948330A4 (fr) 1999-12-01

Family

ID=21817284

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97937142A Withdrawn EP0948330A4 (fr) 1996-08-06 1997-08-06 Antagonistes du recepteur d'il-8

Country Status (3)

Country Link
EP (1) EP0948330A4 (fr)
JP (1) JP2002513384A (fr)
WO (1) WO1998005328A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0932405A4 (fr) 1996-06-27 2001-10-17 Smithkline Beckman Corp Antagonistes des recepteurs d'il-8
TW200418812A (en) 2002-10-29 2004-10-01 Smithkline Beecham Corp IL-8 receptor antagonists
EP1745032B1 (fr) 2004-05-12 2013-07-31 Merck Sharp & Dohme Corp. Antagonistes de chimiokines CXCR1 et CXCR2
MX2008013599A (es) 2006-04-21 2008-10-31 Smithkline Beechman Corp Antagonistas del receptor il-8.
PL2009992T3 (pl) 2006-04-21 2012-11-30 Glaxosmithkline Llc Antagoniści receptora IL-8

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05294935A (ja) * 1991-03-15 1993-11-09 Green Cross Corp:The アミノピリジン系化合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *
See also references of WO9805328A1 *

Also Published As

Publication number Publication date
JP2002513384A (ja) 2002-05-08
EP0948330A1 (fr) 1999-10-13
WO1998005328A1 (fr) 1998-02-12

Similar Documents

Publication Publication Date Title
IL127666A0 (en) IL-8 receptor antagonists
HUP9903922A3 (en) Il-8 receptor antagonists
EP0932405A4 (fr) Antagonistes des recepteurs d'il-8
ZA988100B (en) IL-8 receptor antagonists
IL131004A0 (en) Il-8 receptor antagonists
HUP0000467A3 (en) Il-8 receptor antagonists
IL128501A0 (en) IL-8 receptor antagonists
EP1000017A4 (fr) Antagonistes du recepteur il-8
EP0907362A4 (fr) Antagonistes des recepteurs d'il-8
EP1019035A4 (fr) Antagonistes du recepteur d'il-8
EP0920417A4 (fr) Antagonistes du recepteur de l'il-8
IL131005A0 (en) Il-8 receptor antagonists
HK1028730A1 (en) Il-8 receptor antagonists
EP0923373A4 (fr) Antagonistes du recepteur d'il-8
EP0971908A4 (fr) Antagoniste de recepteurs d'il-8
EP0957907A4 (fr) Antagonistes du recepteur de l'il-8
EP0939634A4 (fr) Antagonistes du recepteur il-8
EP0934066A4 (fr) Antagonistes du recepteur de l'interleukine-8 (il-8)
EP0920253A4 (fr) Antagonistes du recepteur il-8
EP1039903A4 (fr) Antagonistes des recepteurs de l'interleukine-8
EP1047424A4 (fr) Antagonistes des recepteurs il-8
EP0948330A4 (fr) Antagonistes du recepteur d'il-8
PL346178A1 (en) Il-8 receptor antagonists
HUP9903949A3 (en) Il-8 receptor antagonists
HUP9904303A3 (en) Il-8 receptor antagonists

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19990127

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

R17P Request for examination filed (corrected)

Effective date: 19990127

A4 Supplementary search report drawn up and despatched

Effective date: 19991015

AK Designated contracting states

Kind code of ref document: A4

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RIC1 Information provided on ipc code assigned before grant

Free format text: 6A 61K 31/44 A, 6A 61K 31/445 B, 6A 61K 31/495 B, 6A 61K 31/505 B, 6A 61K 31/535 B, 6C 07D 211/56 B, 6C 07D 213/84 B, 6C 07D 213/86 B, 6C 07D 213/88 B, 6C 07D 251/32 B, 6C 07D 213/74 B, 6C 07D 235/06 B, 6C 07D 223/16 B, 6C 07D 333/54 B

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20000204