EP0944362A1 - Systeme et procede pour mesures hemodynamiques non invasives dans des pontages en hemodialyse - Google Patents

Systeme et procede pour mesures hemodynamiques non invasives dans des pontages en hemodialyse

Info

Publication number
EP0944362A1
EP0944362A1 EP97913824A EP97913824A EP0944362A1 EP 0944362 A1 EP0944362 A1 EP 0944362A1 EP 97913824 A EP97913824 A EP 97913824A EP 97913824 A EP97913824 A EP 97913824A EP 0944362 A1 EP0944362 A1 EP 0944362A1
Authority
EP
European Patent Office
Prior art keywords
time
hematocrit
blood flow
measuring
period
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97913824A
Other languages
German (de)
English (en)
Other versions
EP0944362A4 (fr
Inventor
Robert R. Steuer
David R. Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
In-Line Diagnostics Corp
Original Assignee
In-Line Diagnostics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by In-Line Diagnostics Corp filed Critical In-Line Diagnostics Corp
Publication of EP0944362A1 publication Critical patent/EP0944362A1/fr
Publication of EP0944362A4 publication Critical patent/EP0944362A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14535—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring haematocrit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6866—Extracorporeal blood circuits, e.g. dialysis circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1613—Profiling or modelling of patient or predicted treatment evolution or outcome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3607—Regulation parameters
    • A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
    • A61M1/361—Physical characteristics of the blood, e.g. haematocrit, urea before treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3607—Regulation parameters
    • A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
    • A61M1/3612—Physical characteristics of the blood, e.g. haematocrit, urea after treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3613—Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3655—Arterio-venous shunts or fistulae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3656—Monitoring patency or flow at connection sites; Detecting disconnections
    • A61M1/3658—Indicating the amount of purified blood recirculating in the fistula or shunt
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3643—Priming, rinsing before or after use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3663—Flow rate transducers; Flow integrators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/207—Blood composition characteristics hematocrit

Abstract

On évalue quantitativement la recirculation d'accès dans un pontage au moyen d'un procédé selon lequel on injecte à un patient une solution de référence, telle qu'une solution saline, qui se mêle à l'écoulement sanguin en amont du pontage. Au niveau d'un point de la ligne d'accès, on effectue une mesure photométrique de la variation temporelle de l'hématocrite (delta H). Un circuit électronique (150) reçoit des signaux du détecteur (100), compare l'aire d'intégration par rapport au temps du delta H de la solution de référence s'écoulant initialement à travers le pontage, à celle de la solution en recirculation, et produit un affichage de cette recirculation (152).
EP97913824A 1996-10-23 1997-10-22 Systeme et procede pour mesures hemodynamiques non invasives dans des pontages en hemodialyse Withdrawn EP0944362A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2958796P 1996-10-23 1996-10-23
US29587P 1996-10-23
PCT/US1997/019511 WO1998017193A1 (fr) 1996-10-23 1997-10-22 Systeme et procede pour mesures hemodynamiques non invasives dans des pontages en hemodialyse

Publications (2)

Publication Number Publication Date
EP0944362A1 true EP0944362A1 (fr) 1999-09-29
EP0944362A4 EP0944362A4 (fr) 2001-11-21

Family

ID=21849818

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97913824A Withdrawn EP0944362A4 (fr) 1996-10-23 1997-10-22 Systeme et procede pour mesures hemodynamiques non invasives dans des pontages en hemodialyse

Country Status (6)

Country Link
EP (1) EP0944362A4 (fr)
JP (1) JP3622984B2 (fr)
KR (1) KR100498628B1 (fr)
AU (1) AU5092098A (fr)
CA (1) CA2268519A1 (fr)
WO (1) WO1998017193A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153109A (en) 1994-09-16 2000-11-28 Transonic Systmes, Inc. Method and apparatus to measure blood flow rate in hemodialysis shunts
US6514419B2 (en) 1994-09-16 2003-02-04 Transonic Systems, Inc. Method to measure blood flow and recirculation in hemodialysis shunts
US6648845B1 (en) * 1998-01-07 2003-11-18 Fresenius Medical Care North America Method and apparatus for determining hemodialysis parameters
US6868739B1 (en) 1999-10-19 2005-03-22 Transonic Systems, Inc. Method and apparatus to measure blood flow by an introduced volume change
DE10259437B3 (de) 2002-12-19 2004-09-16 Fresenius Medical Care Deutschland Gmbh Verfahren und Vorrichtung zur Bestimmung des Blutflusses in einer blutführenden Leitung
JP4909982B2 (ja) * 2005-03-07 2012-04-04 トランソニック システムズ、インコーポレイテッド 心拍出量を決定するためのシステム
JP4573231B2 (ja) * 2006-11-01 2010-11-04 日機装株式会社 血液浄化装置
JP4573860B2 (ja) * 2007-08-22 2010-11-04 日機装株式会社 血液浄化装置
DE102010015664A1 (de) * 2010-04-20 2011-10-20 Up-Med Gmbh Verfahren und Vorrichtung zur Bestimmung des Fistelflusses einer Fistel für die Dialysebehandlung
DE102013103335A1 (de) * 2013-04-03 2014-10-09 B. Braun Avitum Ag System zur Erfassung eines Zustands einer Dialysatorvorrichtung, und hierfür verwendbare Sensorvorrichtung
JP6559484B2 (ja) * 2015-07-06 2019-08-14 日機装株式会社 血液浄化装置及びその血液浄化装置によるアクセス血管の流量算出方法
JP7061509B2 (ja) * 2018-04-26 2022-04-28 日機装株式会社 血液浄化装置
US11389576B2 (en) * 2018-12-03 2022-07-19 Fresenius Medical Care Holdings, Inc. Determination of patient blood volume at start of a dialysis treatment

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0416808A1 (fr) * 1989-09-01 1991-03-13 Ash Medical System, Incorporated Dispositif de mesure du débit dans une conduite
EP0532432A1 (fr) * 1991-09-10 1993-03-17 Hospal Industrie Rein artificiel
US5312550A (en) * 1992-04-27 1994-05-17 Hester Robert L Method for detecting undesired dialysis recirculation
US5453576A (en) * 1994-10-24 1995-09-26 Transonic Systems Inc. Cardiovascular measurements by sound velocity dilution
EP0693297A1 (fr) * 1994-07-18 1996-01-24 BELLCO S.p.A. Appareil de dialyse
WO1996008305A1 (fr) * 1994-09-16 1996-03-21 Transonic Systems, Inc. Methode de mesure du debit sanguin dans les pontages en hemodialyse
US5510717A (en) * 1992-09-30 1996-04-23 Cobe Laboratories, Inc. Differential conductivity recirculation monitor

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Publication number Priority date Publication date Assignee Title
JPS56104646A (en) * 1980-01-25 1981-08-20 Minolta Camera Kk Optical analyzer for forming ratio of element contained in organism
US5351686A (en) 1990-10-06 1994-10-04 In-Line Diagnostics Corporation Disposable extracorporeal conduit for blood constituent monitoring
US5372136A (en) 1990-10-06 1994-12-13 Noninvasive Medical Technology Corporation System and method for noninvasive hematocrit monitoring
CA2124808A1 (fr) * 1992-10-13 1994-04-28 Vernon H. Troutner Module d'echantillonnage de fluides
EP0847768B1 (fr) * 1992-10-13 2001-09-19 Baxter International Inc. Système de surveillance de l'hémodialyse pour appareils de dialyse
US5507723A (en) * 1994-05-24 1996-04-16 Baxter International, Inc. Method and system for optimizing dialysis clearance

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0416808A1 (fr) * 1989-09-01 1991-03-13 Ash Medical System, Incorporated Dispositif de mesure du débit dans une conduite
EP0532432A1 (fr) * 1991-09-10 1993-03-17 Hospal Industrie Rein artificiel
US5312550A (en) * 1992-04-27 1994-05-17 Hester Robert L Method for detecting undesired dialysis recirculation
US5312550B1 (en) * 1992-04-27 1996-04-23 Robert L Hester Method for detecting undesired dialysis recirculation
US5510717A (en) * 1992-09-30 1996-04-23 Cobe Laboratories, Inc. Differential conductivity recirculation monitor
EP0693297A1 (fr) * 1994-07-18 1996-01-24 BELLCO S.p.A. Appareil de dialyse
WO1996008305A1 (fr) * 1994-09-16 1996-03-21 Transonic Systems, Inc. Methode de mesure du debit sanguin dans les pontages en hemodialyse
US5453576A (en) * 1994-10-24 1995-09-26 Transonic Systems Inc. Cardiovascular measurements by sound velocity dilution

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DEPNER T A ET AL: "CLINICAL MEASUREMENT OF BLOOD FLOW IN HEMODIALYSIS ACCESS FISTULAE AND GRAFTS BY ULTRASOUND DILUTION" ASAIO JOURNAL,US,J.B.LIPPINCOTT CO.,HAGERSTOWN,MD, vol. 41, no. 3, 1 July 1995 (1995-07-01), pages 745-749, XP000542960 ISSN: 1058-2916 *
DEPNER T A ET AL: "HEMODIALYSIS ACCESS RECIRCULATION MEASURED BY ULTRASOUND DILUTION" ASAIO JOURNAL,US,J.B.LIPPINCOTT CO.,HAGERSTOWN,MD, vol. 41, no. 3, 1 July 1995 (1995-07-01), pages 749-753, XP000542961 ISSN: 1058-2916 *
See also references of WO9817193A1 *
SHERMAN R A ET AL: "RATE-RELATED RECIRCULATION: THE EFFECT OF ALTERING BLOOD FLOW ON DIALYZER RECIRCULATION" AMERICAN JOURNAL OF KIDNEY DISEASES, vol. 17, no. 2, 1991, pages 170-173, XP000949035 *

Also Published As

Publication number Publication date
AU5092098A (en) 1998-05-15
CA2268519A1 (fr) 1998-04-30
JP2001506873A (ja) 2001-05-29
KR20000052728A (ko) 2000-08-25
KR100498628B1 (ko) 2005-07-01
WO1998017193A1 (fr) 1998-04-30
JP3622984B2 (ja) 2005-02-23
EP0944362A4 (fr) 2001-11-21

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