EP0922052A4 - Ratten-spezifische ob-rezeptoren und nukleotide, welche für diese kodieren - Google Patents

Ratten-spezifische ob-rezeptoren und nukleotide, welche für diese kodieren

Info

Publication number
EP0922052A4
EP0922052A4 EP97905980A EP97905980A EP0922052A4 EP 0922052 A4 EP0922052 A4 EP 0922052A4 EP 97905980 A EP97905980 A EP 97905980A EP 97905980 A EP97905980 A EP 97905980A EP 0922052 A4 EP0922052 A4 EP 0922052A4
Authority
EP
European Patent Office
Prior art keywords
receptors
nucleotides encoding
rat obesity
obesity
rat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97905980A
Other languages
English (en)
French (fr)
Other versions
EP0922052A1 (de
Inventor
John W Hess
C Thomas Caskey
Qingyun Liu
Michael S Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9608473.6A external-priority patent/GB9608473D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP0922052A1 publication Critical patent/EP0922052A1/de
Publication of EP0922052A4 publication Critical patent/EP0922052A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP97905980A 1996-02-22 1997-02-18 Ratten-spezifische ob-rezeptoren und nukleotide, welche für diese kodieren Withdrawn EP0922052A4 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US9040596P 1996-02-22 1996-02-22
US90405P 1996-02-22
US1396996P 1996-03-22 1996-03-22
US13969P 1996-03-22
GBGB9608473.6A GB9608473D0 (en) 1996-04-25 1996-04-25 Rat OB receptors and nucleotides encoding them
GB9608473 1996-04-25
PCT/US1997/002397 WO1997031015A1 (en) 1996-02-22 1997-02-18 Rat ob receptors and nucleotides encoding them

Publications (2)

Publication Number Publication Date
EP0922052A1 EP0922052A1 (de) 1999-06-16
EP0922052A4 true EP0922052A4 (de) 2001-08-01

Family

ID=27268258

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97905980A Withdrawn EP0922052A4 (de) 1996-02-22 1997-02-18 Ratten-spezifische ob-rezeptoren und nukleotide, welche für diese kodieren

Country Status (4)

Country Link
EP (1) EP0922052A4 (de)
JP (1) JP2002515739A (de)
CA (1) CA2246226A1 (de)
WO (1) WO1997031015A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US7063958B1 (en) 1996-01-16 2006-06-20 The Rockefeller University Nucleic acids db, the receptor for leptin
US7148004B1 (en) 1997-01-16 2006-12-12 The Rockefeller University Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight
US7084252B1 (en) 1996-01-16 2006-08-01 The Rockefeller University DB, the receptor for leptin
US7619079B2 (en) 1996-02-14 2009-11-17 The Rockefeller University Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof
CA2253832A1 (en) * 1996-05-06 1997-11-13 Merck & Co., Inc. Ob receptor isoforms and nucleic acids encoding them
US6258944B1 (en) * 1996-05-06 2001-07-10 Merck & Co., Inc. OB receptor isoforms and nucleic acids encoding them

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHUA S C ET AL: "PHENOTYPES OF MOUSE DIABETES AND RAT FATTY DUE TO MUTATIONS IN THE OB (LEPTIN) RECEPTOR", SCIENCE,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,,US, vol. 271, 16 February 1996 (1996-02-16), pages 994 - 996, XP000941868, ISSN: 0036-8075 *
IIDA M ET AL: "SUBSTITUTION AT CODON 269 (GLUTANINE PROLINE) OF THE LEPTIN RECEPTOR (OB-R) CDNA IS THE ONLY MUTATION FOUND IN THE ZUCKER FATTY (FA/FA) RAT", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,US,ACADEMIC PRESS INC. ORLANDO, FL, vol. 224, no. 2, 16 July 1996 (1996-07-16), pages 597 - 604, XP002029745, ISSN: 0006-291X *
PHILLIPS ET AL.: "Leptin receptor missense mutation in the fatty Zucker rat", NATURE GENETICS, 13 May 1996 (1996-05-13), pages 18-19, XP000611494 *
See also references of WO9731015A1 *
STEPHENS ET AL.: "The role of neuropeptide Y in the antiobesity action of the obese gene product", NATURE, vol. 377, 12 October 1995 (1995-10-12), pages 530 - 532, XP000999194 *

Also Published As

Publication number Publication date
WO1997031015A1 (en) 1997-08-28
JP2002515739A (ja) 2002-05-28
EP0922052A1 (de) 1999-06-16
CA2246226A1 (en) 1997-08-28

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Legal Events

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