EP0900282A4 - Ob receptor isoforms and nucleic acids encoding them - Google Patents

Ob receptor isoforms and nucleic acids encoding them

Info

Publication number
EP0900282A4
EP0900282A4 EP97922646A EP97922646A EP0900282A4 EP 0900282 A4 EP0900282 A4 EP 0900282A4 EP 97922646 A EP97922646 A EP 97922646A EP 97922646 A EP97922646 A EP 97922646A EP 0900282 A4 EP0900282 A4 EP 0900282A4
Authority
EP
European Patent Office
Prior art keywords
nucleic acids
acids encoding
receptor isoforms
isoforms
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97922646A
Other languages
German (de)
French (fr)
Other versions
EP0900282A1 (en
Inventor
C Thomas Caskey
John W Hess
Patricia Hey
Michael S Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9610995.4A external-priority patent/GB9610995D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP0900282A1 publication Critical patent/EP0900282A1/en
Publication of EP0900282A4 publication Critical patent/EP0900282A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP97922646A 1996-05-06 1997-05-02 Ob receptor isoforms and nucleic acids encoding them Withdrawn EP0900282A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1689996P 1996-05-06 1996-05-06
US16899P 1996-05-06
GBGB9610995.4A GB9610995D0 (en) 1996-05-24 1996-05-24 OB Receptor isoforms and nucleic acids encoding them
GB9610995 1996-05-24
PCT/US1997/007521 WO1997042340A1 (en) 1996-05-06 1997-05-02 Ob receptor isoforms and nucleic acids encoding them

Publications (2)

Publication Number Publication Date
EP0900282A1 EP0900282A1 (en) 1999-03-10
EP0900282A4 true EP0900282A4 (en) 2001-04-11

Family

ID=26309397

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97922646A Withdrawn EP0900282A4 (en) 1996-05-06 1997-05-02 Ob receptor isoforms and nucleic acids encoding them

Country Status (4)

Country Link
EP (1) EP0900282A4 (en)
JP (1) JP2000512486A (en)
CA (1) CA2253832A1 (en)
WO (1) WO1997042340A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) * 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US7063958B1 (en) 1996-01-16 2006-06-20 The Rockefeller University Nucleic acids db, the receptor for leptin
US7084252B1 (en) 1996-01-16 2006-08-01 The Rockefeller University DB, the receptor for leptin
US7148004B1 (en) 1997-01-16 2006-12-12 The Rockefeller University Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight
US7619079B2 (en) 1996-02-14 2009-11-17 The Rockefeller University Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof
US6770444B2 (en) 1998-07-16 2004-08-03 Synaptic Pharmaceutical Corporation Methods of identifying or screening for agents that binds the Ob-Re

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997031015A1 (en) * 1996-02-22 1997-08-28 Merck & Co., Inc. Rat ob receptors and nucleotides encoding them
WO1997041217A1 (en) * 1996-04-30 1997-11-06 Otsuka Pharmaceutical Co., Ltd. ob PROTEIN RECEPTOR GENES AND USE OF THE SAME

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228839A1 (en) * 1992-08-29 1994-03-03 Behringwerke Ag Methods for the detection and determination of mediators
US5643748A (en) * 1994-09-14 1997-07-01 Progenitor, Inc. HU-B1.219, a novel human hematopoietin receptor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997031015A1 (en) * 1996-02-22 1997-08-28 Merck & Co., Inc. Rat ob receptors and nucleotides encoding them
WO1997041217A1 (en) * 1996-04-30 1997-11-06 Otsuka Pharmaceutical Co., Ltd. ob PROTEIN RECEPTOR GENES AND USE OF THE SAME

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"LEPTIN RECEPTOR MISSENSE MUTATION IN THE FATTY ZUCKER RAT", NATURE GENETICS,US,NEW YORK, NY, vol. 13, no. 1, 1 May 1995 (1995-05-01), pages 18 - 19, XP000611494, ISSN: 1061-4036 *
See also references of WO9742340A1 *
TAKASHI MURAKAMI ET AL: "CLONING OF RAT OBESE CDNA AND ITS EXPRESSION IN OBESE RATS", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,US,ACADEMIC PRESS INC. ORLANDO, FL, vol. 209, no. 3, 26 April 1995 (1995-04-26), pages 944 - 952, XP000602094, ISSN: 0006-291X *
WANG M. ET AL.: "A novel leptin receptor isoform in rat", FEBS LETTERS, vol. 392, August 1996 (1996-08-01), pages 87 - 90, XP000973254 *

Also Published As

Publication number Publication date
WO1997042340A1 (en) 1997-11-13
CA2253832A1 (en) 1997-11-13
JP2000512486A (en) 2000-09-26
EP0900282A1 (en) 1999-03-10

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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A4 Supplementary search report drawn up and despatched

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