EP0880351A4 - Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials - Google Patents

Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials

Info

Publication number
EP0880351A4
EP0880351A4 EP96906426A EP96906426A EP0880351A4 EP 0880351 A4 EP0880351 A4 EP 0880351A4 EP 96906426 A EP96906426 A EP 96906426A EP 96906426 A EP96906426 A EP 96906426A EP 0880351 A4 EP0880351 A4 EP 0880351A4
Authority
EP
European Patent Office
Prior art keywords
antimicrobials
ophthalmic
quaternary ammonium
ammonium compounds
polymeric quaternary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96906426A
Other languages
German (de)
French (fr)
Other versions
EP0880351A1 (en
Inventor
Evan P Kyba
Joonsup Park
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of EP0880351A1 publication Critical patent/EP0880351A1/en
Publication of EP0880351A4 publication Critical patent/EP0880351A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/74—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C215/90—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with quaternised amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62—Quaternary ammonium compounds
    • C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
EP96906426A 1996-02-14 1996-02-14 Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials Withdrawn EP0880351A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/001975 WO1997029741A1 (en) 1996-02-14 1996-02-14 Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials

Publications (2)

Publication Number Publication Date
EP0880351A1 EP0880351A1 (en) 1998-12-02
EP0880351A4 true EP0880351A4 (en) 2003-01-08

Family

ID=22254716

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96906426A Withdrawn EP0880351A4 (en) 1996-02-14 1996-02-14 Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials

Country Status (4)

Country Link
EP (1) EP0880351A4 (en)
JP (1) JP2000505486A (en)
AU (1) AU712908B2 (en)
WO (1) WO1997029741A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106561631B (en) * 2016-10-13 2020-12-11 刘鹏飞 Saliva preserving fluid and preparation method and application thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4407791A (en) * 1981-09-28 1983-10-04 Alcon Laboratories, Inc. Ophthalmic solutions
US4525346A (en) * 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
EP0384666A2 (en) * 1989-02-21 1990-08-29 BAUSCH & LOMB INCORPORATED Method and composition for cleaning and disinfecting contact lenses
EP0456467A2 (en) * 1990-05-09 1991-11-13 Alcon Laboratories, Inc. Contact lens cleaning and disinfecting with combinations of polymeric quaternary ammonium compounds and enzymes
US5591426A (en) * 1993-07-02 1997-01-07 Bausch & Lomb Incorporated Ophthalmic solution for artificial tears
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3874870A (en) * 1973-12-18 1975-04-01 Mill Master Onyx Corp Microbiocidal polymeric quarternary ammonium compounds
US4025653A (en) * 1975-04-07 1977-05-24 Millmaster Onyx Corporation Microbiocidal polymeric quaternary ammonium compounds
US4089977A (en) * 1976-11-24 1978-05-16 Kewanee Industries Polymeric anti-microbial agent
US4444750A (en) * 1980-11-17 1984-04-24 Millmaster Onyx Group, Inc. Method of conditioning hair

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4407791A (en) * 1981-09-28 1983-10-04 Alcon Laboratories, Inc. Ophthalmic solutions
US4525346A (en) * 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
EP0384666A2 (en) * 1989-02-21 1990-08-29 BAUSCH & LOMB INCORPORATED Method and composition for cleaning and disinfecting contact lenses
US5096607A (en) * 1989-02-21 1992-03-17 Bausch & Lomb Incorporated Method for cleaning and disinfecting contact lenses
US5096607B1 (en) * 1989-02-21 1998-10-27 Bausch & Lomb Method for cleaning and disinfecting contact lenses
US5096607C2 (en) * 1989-02-21 2002-08-20 Bausch & Lomb Method for cleaning and disinfecting contact lenses
EP0456467A2 (en) * 1990-05-09 1991-11-13 Alcon Laboratories, Inc. Contact lens cleaning and disinfecting with combinations of polymeric quaternary ammonium compounds and enzymes
US5591426A (en) * 1993-07-02 1997-01-07 Bausch & Lomb Incorporated Ophthalmic solution for artificial tears
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GOOD, R ET AL: "Colorimetric Determination of a Polymeric Quaternary Ammonium Animicrobial Preservative in an Ophthalmic Solution", J ASSOC OFF ANAL CHEM, 1987, pages 979 - 980, XP008004682 *
See also references of WO9729741A1 *

Also Published As

Publication number Publication date
JP2000505486A (en) 2000-05-09
AU4980896A (en) 1997-09-02
EP0880351A1 (en) 1998-12-02
AU712908B2 (en) 1999-11-18
WO1997029741A1 (en) 1997-08-21

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