EP0868209A1 - Melange de ciment pour os - Google Patents

Melange de ciment pour os

Info

Publication number
EP0868209A1
EP0868209A1 EP96941128A EP96941128A EP0868209A1 EP 0868209 A1 EP0868209 A1 EP 0868209A1 EP 96941128 A EP96941128 A EP 96941128A EP 96941128 A EP96941128 A EP 96941128A EP 0868209 A1 EP0868209 A1 EP 0868209A1
Authority
EP
European Patent Office
Prior art keywords
shaft
mixing
chamber
handle
cement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96941128A
Other languages
German (de)
English (en)
Inventor
Neil David Watkins
John Robert Naybour
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DePuy International Ltd
Original Assignee
DePuy International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DePuy International Ltd filed Critical DePuy International Ltd
Publication of EP0868209A1 publication Critical patent/EP0868209A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/712—Feed mechanisms for feeding fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50—Mixing liquids with solids
    • B01F23/565—Mixing liquids with solids by introducing liquids in solid material, e.g. to obtain slurries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/40—Mixers with shaking, oscillating, or vibrating mechanisms with an axially oscillating rotary stirrer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7173—Feed mechanisms characterised by the means for feeding the components to the mixer using gravity, e.g. from a hopper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7173—Feed mechanisms characterised by the means for feeding the components to the mixer using gravity, e.g. from a hopper
    • B01F35/71731—Feed mechanisms characterised by the means for feeding the components to the mixer using gravity, e.g. from a hopper using a hopper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/718—Feed mechanisms characterised by the means for feeding the components to the mixer using vacuum, under pressure in a closed receptacle or circuit system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/71805—Feed mechanisms characterised by the means for feeding the components to the mixer using valves, gates, orifices or openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/75425—Discharge mechanisms characterised by the means for discharging the components from the mixer using pistons or plungers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/20—Mixing of ingredients for bone cement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/05—Stirrers
    • B01F27/11—Stirrers characterised by the configuration of the stirrers
    • B01F27/112—Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/70—Mixers specially adapted for working at sub- or super-atmospheric pressure, e.g. combined with de-foaming
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/32005—Type of drive
    • B01F35/3202—Hand driven
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms

Definitions

  • This invention relates to a device for mixing bone cement.
  • Bone cement is generally supplied as two separately packaged reactive components which are mixed to form a cement.
  • the cement is malleable initially after mixing, but hardens as the components react together.
  • the cement can be worked into contact with the bone to which is to be secured when still malleable, for example by injection using a syringe into a bone cavity.
  • the cement components generally comprise a powder and a liquid.
  • a cement might comprise liquid methyl methacrylate monomer and poly(methyl methacrylate) and/or styrene methyl methacrylate copolymer in powder form.
  • Other combinations of liquid monomeric species with powders comprising one or more different types of polymer can be used.
  • Thorough mixing of the components is essential in order for the bond provided by the cement to have optimum strength and life.
  • Mixing of the components generally involves adding the components sequentially to a mixing chamber. This results in one of the components resting or "floating" on the other component. Mixing then requires relative vertical movement of the cement components so that there is a substantially constant distribution of powder and liquid throughout the depth of the chamber, before powder and liquid are mixed intimately together.
  • the mixing of the components should of course take place under sterile conditions, and preferably under conditions which minimise air bubbles or other voids m the mixed cement .
  • O-A-93/22041 discloses a device for mixing bone cement which includes a lid having an aperture in it which can receive an agitator rod.
  • the rod can be attached to an agitator which can be moved axially within a mixing chamber (provided by a syringe body) to cause cement components withm the chamber to mix.
  • the rod has a handle at its outer end by which the rod can be gripped to move the agitator axially in the chamber
  • the present invention provides a device for mixing bone cement m which the mixing member can be manipulated on a shaft by means of a handle with a lateral grip portion for moving the mixing member up and down to distribute bone cement components evenly throughout the depth of the mixing chamber, and a formation on the grip portion which facilitates rotation of the mixing member
  • the invention provides a device for mixing bone cement which comprises
  • a handle for the mixing memoer having a grip portion extending laterally of the said shaft and a formation on the grip portion of the handle spaced apart from the shaft.
  • the device of the present invention facilitates thorough mixing of bone cement components in a mixing chamber, by an initial mixing step which involves axial movement of the mixing member in the mixing chamber, with or without a simultaneous rotatory component of motion This can make the distribution of bone cement components, added sequentially to the chamber so that they are arranged in layers, relatively uniform throughout the depth of the chamber
  • the rotation of the mixing member facilitated by the formation on the grip portion can ensure thorough mixing of the cement components with uniform dispersion of a particulate component through the other component or components, for example of a particulate component m a liquid component.
  • the handle has two (or more) grip portions, extending laterally of the shaft on opposite sides thereof.
  • the provision of two or more grip portions spaced apart around the shaft enables the handle to be gripped so as to move the mixing member axially, with or without a rotatory component of motion, within the mixing chamber without large transverse forces applied thereto.
  • the formation that s provided on the grip portion of the handle spaced apart from the shaft is a protrusion that can be gripped by the user of the device to cause the grip portion to rotate around the axis provided by the shaft.
  • the protrusion extends from the grip portion of the handle in a direction generally parallel to the axis of shaft. It need not extend precisely parallel to the shaft: for example the angle between the axis of the shaft and the axis of the protrusion might be as much as 15°, 25° or more.
  • the protrusion is able to rotate on the grip portion of the handle.
  • the formation might be for example a recess by which the grip portion can be gripped conveniently to cause it to rotate.
  • the mixing member includes at least one laterally extending paddle located at or towards the end of the mixing member in the mixing chamber.
  • the design of the paddles should generally be such that, on rotation of the mixing member, substantially all of the cement components are contacted and moved, and thereby mixed.
  • such spaced apart paddles are offset relative to one another around the shaft of the mixing member.
  • At least one of the paddles can be non-planar when viewed in a direction parallel to the shaft so that, when the mixing member is moved axially, the paddle imparts a lateral movement to cement that it contacts. This can facilitate thorough mixing of the cement components m the first, axial movement phase of using the device.
  • the paddles can be provided as separate members that are individually attached to a shaft extending throughout the mixing chamber.
  • two or more paddles may be connected or otherwise attached to one another (for example by being formed as a single article by moulding) , and then connected to the shaft which need not then extend throughout the mixing chamber
  • the paddles can be formed with the shaft, for example by a moulding operation.
  • the device of the invention includes a lid on the mixing chamber, having an aperture m it through which the shaft of the mixing member extends.
  • the lid can include an appropriate seal between it and the shaft to minimise leakage of cement components through the aperture.
  • the seal might be provided by a gasket (for example formed from a material with elastomer properties such as natural rubber, nitrile rubber, or a silicone rubber) m the aperture which engages the shaft with a snug sliding fit
  • the mixing chamber can have a port which can be connected to an appropriate extractor, for example a vacuum pump, by which vapours can be removed from the chamber, minimising hazards to the operator of the device.
  • an appropriate extractor for example a vacuum pump
  • the port can conveniently be provided in the lid of the chamber
  • Appropriate filters can be provided to control the extraction of particulate material from the mixing chamber when connected to the extractor.
  • components of the device such as the mixing chamber and the mixing member are formed from polymeric materials. It can be preferred to form the mixing chamber from a translucent or more preferably a transparent material, such as a polyester or a polycarbonate. This has the advantage of enabling the mixing process to be observed visually.
  • the handle and the paddles on the mixing member can be formed from a polyolefin such as a polyethylene or a polypropylene, preferably by a moulding process.
  • the shaft of the mixing member can also be formed from a polymeric material although use of a metal (for example aluminium or an alloy thereof) can be preferred because of the greater rigidity that can be available from it.
  • the shaft of the mixing member is hollow. This can enable bone cement components to be mixed in the chamber can be introduced into the chamber through the shaft.
  • An appropriate port can be provided in the handle if necessary if the handle s provided on the top of the shaft .
  • the mixing chamber includes a piston which can be moved axially through the chamber to extrude mixed cement from the chamber as from a syringe.
  • the chamber is arranged so that the mixed cement is extruded through the end thereof through which the shaft of the mixing member extends.
  • the mixing member may be removable from withm the mixing chamber so that the cement can be extruded from the chamber through the aperture previously occupied by the shaft.
  • An appropriate slot can be provided for this purpose at the end of the mixing chamber to which the lid is attached.
  • the mixing member can be removed from the mixing chamber together with an end cap through which it extends, and a nozzle can be positioned on the chamber for extrusion of the mixed cement .
  • the piston can be restrained from axial movement with the chamber until it is required to extrude the cement from the chamber, for example by means of a pm which extends across the chamber to tie the piston to the chamber walls .
  • a port in the cap for connection to an extractor can facilitate extrusion of cement with minimum air or other voids in it, by maintaining the chamber at reduced pressure during the extrusion step.
  • the piston preferably has associated with it a device for ensuring that cement is not retained in a nozzle extending from the outlet of the mixing chamber, of the kind disclosed in EP-A-10858 .
  • Figure 1 is an sectional elevation of one embodiment of the device.
  • Figure 2 is an isometric view of a number of components of the device.
  • Figure 1 shows a cylindrical body 1 defining a mixing chamber 3.
  • the chamber 3 is sealed at its lower end by the head of a piston element 5.
  • a nitrile rubber "0" ring 7 seals the gap between the wall of the cylinder 1 and the piston head 5.
  • the other end of the chamber is sealed by a lid 9 which surrounds the end portion 11 of the cylinder 1.
  • the lid 9 is provided with a port 13 allowing access to the chamber 3.
  • the lid 9 is also provided with a central aperture which receives an axially extending shaft 15 of the mixing member.
  • the shaft is sealed relative to the lid by means of an "0" ring 17.
  • the shaft 15 provides a mounting for a series of radially extending paddle elements 19. These extend over substantially the full width of the chamber 3.
  • the paddles consist of stem - 7 - portions 21 and head portions extending substantially parallel to the axis of the shaft 23.
  • the shaft 15 is connected to a handle 25 which provides two laterally extending grip portions 27 each provided with indents 29 which receive the fingers of the operator in use. These grip portions 27 facilitate axial movement of the shaft and mounted paddle elements relative to the cylinder in a reciprocating style motion.
  • the handle 25 is also provided with an additional formation 31 which facilitates rotation of the shaft 15 and stirrer elements mounted thereon.
  • a collar 33 mounted on a shaft and the head surface 35 of the piston 5 control the position of the mixing elements when fully inserted into the chamber.
  • the abutment of a further collar surface 37 with the top of the lid restrains the mixing unit relative to the chamber in the fully retracted position.
  • the piston head 5 and bottom walls of the cylinder 1 are provided with a through bore 39 which facilitates the insertion of a pin, 39, to fixedly locate the piston relative to the cylinder during the mixing stage.
  • the shaft 15 is hollow and is provided with a series of radially extending apertures 41 which are connected via the shaft to an inlet 43.
  • the piston head 5 is fixedly located by a p 39 relative to the bottom end of the cylinder 1.
  • the solid component, commonly in powder form, of the cement to be mixed is then placed in the cylinder.
  • the mixing unit mounted on the head can then be engaged with the cylinder and the lid secured to give a good seal.
  • the liquid component of the system can then readily be introduced by means of the hopper 43 down through the shaft 15 and out through apertures 41 into contact with the powder material already in the chamber.
  • the break off plug 44 provided on the hopper 43 can then be used to seal the inlet in the handle prior to mixing.
  • Axial motion of the mixing unit in a reciprocating manner causes the liquid and powder components to mix together.
  • By rotating the mixing unit by handle 31 intimate mixing of the powder and liquid to give the desired cement can be effected.
  • Vapours produced during the mixing process can readily be extracted from the system by means of port 13 which can be connected to a vacuum pump for instance.
  • the extent and progress of the mixing stage can be observed.
  • the mixing unit can be removed and an application head 50 attached to the cylinder.
  • an application head 50 attached to the cylinder.
  • the piston 5 can then be axially advanced along the cylinder 1 causing the cement to extrude through the applicator to the desired location.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Prostheses (AREA)

Abstract

Un dispositif permettant de mélanger un ciment pour os comprend une chambre de mélange comportant un couvercle; un élément mélangeur fixé sur un arbre sortant de la chambre par un orifice du couvercle, qui permet (i) de déplacer axialement l'élément à l'intérieur de la chambre et (ii) de le faire tourner autour de l'axe constitué par l'arbre; et un manche destiné à l'élément mélangeur, qui comporte une partie poignée dirigée latéralement par rapport à l'arbre et une formation disposée sur la partie poignée, à distance de l'arbre. La formation peut être une saillie partant de la partie poignée du manche selon une direction généralement parallèle à l'axe de l'arbre, que l'utilisateur du dispositif peut tenir pour faire tourner la partie poignée autour de l'axe.
EP96941128A 1995-12-09 1996-12-05 Melange de ciment pour os Withdrawn EP0868209A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9525209.4A GB9525209D0 (en) 1995-12-09 1995-12-09 Mixing bone cement
GB9525209 1995-12-09
PCT/GB1996/002997 WO1997021485A1 (fr) 1995-12-09 1996-12-05 Melange de ciment pour os

Publications (1)

Publication Number Publication Date
EP0868209A1 true EP0868209A1 (fr) 1998-10-07

Family

ID=10785186

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96941128A Withdrawn EP0868209A1 (fr) 1995-12-09 1996-12-05 Melange de ciment pour os

Country Status (5)

Country Link
EP (1) EP0868209A1 (fr)
AU (1) AU1037797A (fr)
GB (1) GB9525209D0 (fr)
WO (1) WO1997021485A1 (fr)
ZA (1) ZA9610169B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10856923B2 (en) 2018-01-22 2020-12-08 Warsaw Orthopedic, Inc. Manual mixer

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4159202B2 (ja) 1998-12-21 2008-10-01 日本特殊陶業株式会社 リン酸カルシウム系セメント用混練器具及びリン酸カルシウム系セメント混練物の調製方法
US6689823B1 (en) 1999-03-31 2004-02-10 The Brigham And Women's Hospital, Inc. Nanocomposite surgical materials and method of producing them
JP2001104324A (ja) 1999-10-06 2001-04-17 Ngk Spark Plug Co Ltd 薬剤押出用補助器具及びそれを用いた薬剤の押出方法
EP1090609A1 (fr) 1999-10-07 2001-04-11 NGK Spark Plug Company Limited Dispositif et procédé pour préparer du ciment à base de phosphate de calcium
US20020191487A1 (en) 2000-10-25 2002-12-19 Kyphon Inc. Systems and methods for mixing and transferring flowable materials
GB0218310D0 (en) * 2002-08-07 2002-09-11 Depuy Int Ltd An instrument for preparing a bone cement material
US20040267272A1 (en) 2003-05-12 2004-12-30 Henniges Bruce D Bone cement mixing and delivery system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3358971A (en) * 1965-06-21 1967-12-19 Whip Mix Corp Investment mixer
IT1169505B (it) * 1983-02-24 1987-06-03 Luciano Occelli Procedimento ed apparecchio per la mescolazione sotto vuoto di impasti per uso odontotecnico,orafo o simile
US4676655A (en) * 1985-11-18 1987-06-30 Isidore Handler Plunger type cartridge mixer for fluent materials
DE3708803A1 (de) * 1987-03-18 1988-09-29 Fischbach A Kunststoff Kg Mischvorrichtung fuer pastoese mehrkomponenten-massen
DE4243877C2 (de) * 1992-12-23 1997-03-20 Volkmar Dipl Ing Dr Me Jansson Verfahren und Vorrichtung zum Anmischen von Knochenzement

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO9721485A1 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10856923B2 (en) 2018-01-22 2020-12-08 Warsaw Orthopedic, Inc. Manual mixer
US11896276B2 (en) 2018-01-22 2024-02-13 Medtronic Holding Company Sàrl Method of using manual mixer

Also Published As

Publication number Publication date
WO1997021485A1 (fr) 1997-06-19
GB9525209D0 (en) 1996-02-07
ZA9610169B (en) 1997-06-23
AU1037797A (en) 1997-07-03

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