EP0865279A4 - Hemoregulatory compounds - Google Patents

Hemoregulatory compounds

Info

Publication number
EP0865279A4
EP0865279A4 EP96941338A EP96941338A EP0865279A4 EP 0865279 A4 EP0865279 A4 EP 0865279A4 EP 96941338 A EP96941338 A EP 96941338A EP 96941338 A EP96941338 A EP 96941338A EP 0865279 A4 EP0865279 A4 EP 0865279A4
Authority
EP
European Patent Office
Prior art keywords
hemoregulatory
compounds
hemoregulatory compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP96941338A
Other languages
German (de)
French (fr)
Other versions
EP0865279A1 (en
Inventor
Pradip Kumar Bhatnagar
Dirk Andries Heerding
Michael Hartmann
Johann Hiebl
Peter Kremminger
Franz Rovenszky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Austria GmbH
SmithKline Beecham Corp
Original Assignee
Nycomed Austria GmbH
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Austria GmbH, SmithKline Beecham Corp filed Critical Nycomed Austria GmbH
Publication of EP0865279A1 publication Critical patent/EP0865279A1/en
Publication of EP0865279A4 publication Critical patent/EP0865279A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
EP96941338A 1995-11-13 1996-11-12 Hemoregulatory compounds Withdrawn EP0865279A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US663895P 1995-11-13 1995-11-13
US664395P 1995-11-13 1995-11-13
US6643P 1995-11-13
US6638P 1995-11-13
US1553696P 1996-04-17 1996-04-17
US15536P 1996-04-17
PCT/US1996/018053 WO1997017963A1 (en) 1995-11-13 1996-11-12 Hemoregulatory compounds

Publications (2)

Publication Number Publication Date
EP0865279A1 EP0865279A1 (en) 1998-09-23
EP0865279A4 true EP0865279A4 (en) 1999-03-03

Family

ID=27358160

Family Applications (1)

Application Number Title Priority Date Filing Date
EP96941338A Withdrawn EP0865279A4 (en) 1995-11-13 1996-11-12 Hemoregulatory compounds

Country Status (3)

Country Link
EP (1) EP0865279A4 (en)
JP (1) JP2000500455A (en)
WO (1) WO1997017963A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6114357A (en) * 1995-11-13 2000-09-05 Smithkline Beecham Corporation Hemoregulatory compounds
US7018642B2 (en) 2001-04-27 2006-03-28 The Procter & Gamble Company Compounds, compositions, and methods for controlling biofilms
MX2012010574A (en) * 2010-03-12 2012-10-09 Procter & Gamble Liquid detergent compositions comprising ph tuneable amido-gellants, and processes for making.
AR080507A1 (en) * 2010-03-12 2012-04-11 Procter & Gamble COMPOSITIONS OF LIQUID DETERGENTS THAT INCLUDE A DIAMID GELIFIER AND PROCESSES TO PREPARE THEM

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
ACTA POL. PHARM. (1968), 25(4), 367-73 CODEN: APPHAX *
BIOORG. MED. CHEM. (1996), 4(7), 1121-1128; ISSN: 0968-0896 *
CHEMICAL ABSTRACTS 13TH COLLECTIVE CHEMICAL SUBSTANCE INDEX., COLUMBUS US, pages 219, XP002088705 *
CHEMICAL ABSTRACTS 1972-1976 COLLECTIVE CHEMICAL SUBSTANCE INDEX., COLUMBUS US, XP002088704 *
CHEMICAL ABSTRACTS, vol. 125, no. 19, 4 November 1996, Columbus, Ohio, US; abstract no. 248409d, HOPKINS, R. BRUCE ET AL: "Synthesis and structure of chiral macrocycles containing 2,2'-bipyridine subunits" XP002088709 *
CHEMICAL ABSTRACTS, vol. 70, no. 19, 12 May 1969, Columbus, Ohio, US; abstract no. 87512k, MOLL, MARIA: "Synthesis of quinaldine derivatives. I. N,N'- polymethylenebis(quinaldamides) and -(4-hydroxyquinaldamides)" XP002088706 *
CHEMICAL ABSTRACTS, vol. 84, no. 24, 14 June 1976, Columbus, Ohio, US; abstract no. 173113b, JUN, MOO-JIN ET AL: "Stereochemistry of complexes of multidentate ligands. IV. Stereoselective cobalt(III) ion complexes of 1,7-bis(2-S-pyrrolidyl)- 2,6-diazaheptane" XP002088708 *
CHEMICAL ABSTRACTS, vol. 89, no. 17, 23 October 1978, Columbus, Ohio, US; abstract no. 146722w, BARNES, D. J. ET AL: "Synthesis of novel bis(amides) by means of triphenyl phosphite intermediates" XP002088707 *
J. CHEM. ENG. DATA (1978), 23(4), 349-50 CODEN: JCEAAX;ISSN: 0021-9568 *
J. COORD. CHEM. (1975), 5(1), 1-11 CODEN: JCCMBQ *
See also references of WO9717963A1 *

Also Published As

Publication number Publication date
EP0865279A1 (en) 1998-09-23
WO1997017963A1 (en) 1997-05-22
JP2000500455A (en) 2000-01-18

Similar Documents

Publication Publication Date Title
GB9508810D0 (en) Compounds
GB9500691D0 (en) Compounds
GB9504910D0 (en) Compounds
EP0873117A4 (en) Hemoregulatory compounds
EP0866700A4 (en) Hemoregulatory compounds
EP0869793A4 (en) Hemoregulatory compounds
EP0861076A4 (en) Hemoregulatory compounds
EP0874638A4 (en) Hemoregulatory compounds
EP0861029A4 (en) Hemoregulatory compounds
EP0866698A4 (en) Hemoregulatory compounds
EP0865279A4 (en) Hemoregulatory compounds
EP0861078A4 (en) Hemoregulatory compounds
EP0861255A4 (en) Hemoregulatory compounds
EP0861030A4 (en) Hemoregulatory compounds
GB9515930D0 (en) Anti-trichomonal compounds
EP0861254A4 (en) Hemoregulatory compounds
EP1021443A4 (en) Hemoregulatory compounds
EP0877611A4 (en) Hemoregulatory compounds
EP0861080A4 (en) Hemoregulatory compounds
GB9504948D0 (en) Compounds
GB9502540D0 (en) Compounds
EP0777665A4 (en) Hemoregulatory compounds
ZA969523B (en) Hemoregulatory compounds.
GB9504801D0 (en) Compounds
GB9502983D0 (en) Compounds

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19980518

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): BE CH DE ES FR GB IT LI NL

RHK1 Main classification (correction)

Ipc: C07D213/81

A4 Supplementary search report drawn up and despatched
AK Designated contracting states

Kind code of ref document: A4

Designated state(s): BE CH DE ES FR GB IT LI NL

17Q First examination report despatched

Effective date: 19990729

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20030602